{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T21:58:21Z","timestamp":1788904701071,"version":"build-2803163510"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,11,13]],"date-time":"2021-11-13T00:00:00Z","timestamp":1636761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,11,13]],"date-time":"2021-11-13T00:00:00Z","timestamp":1636761600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Surg"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background\/Purpose<\/jats:title>\n                <jats:p>To investigate the clinical manifestations, treatments of retrograde intussusception and summarize the experience.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Children with retrograde intussusception treated in our hospital from January 2011 to January 2021 were retrospectively analysed. Demographics, clinical manifestations, preoperative colour Doppler ultrasound (CDU) findings, findings during surgery and follow-up results were collected.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A total of 4719 cases of intussusception were treated in our department, including 12 cases of retrograde intussusception (0.25%). There were 8 males and 4 females.The age ranged from 4.1 to 14.3\u00a0months, with an average of (8.3\u2009\u00b1\u20092.8) months.; The weight ranged from 5.5 to 12.6\u00a0kg, with an average of (9.4\u2009\u00b1\u20092.3) kg; The onset time ranged from 6 to 15\u00a0h, with an average of (10.0\u2009\u00b1\u20092.4) h. All the children received CDU examination before surgery, and in one case, the possibility of 2 intussusception masses was considered. Emergency surgical exploration was performed after the failure of air enema reduction. During the operation, multiple types of intussusception were found (coincidence of anterograde and retrograde intussusception). The pattern of anterograde intussusception was all ileo-ileo-colic variety and the retrograde intussusception was proximal sigmoid colon into descending colon. All the children were successfully reduced by manual reduction without intestinal necrosis or intestinal malformation. All children were discharged 6\u20137\u00a0days after surgery, and had no recurrence after 3\u20136\u00a0months of follow-up.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Retrograde intussusception is easily misdiagnosed before surgery. During air enema, if the intussusception mass was fixed and did not move with increasing pressure, we should be aware of the possibility of retrograde intussusception, and the enema pressure should not be too large to avoid intestinal perforation. If the intraoperative position of the intussusception mass was not consistent with that of the preoperative enema, it was recommended to use bimanual examination to explore whether there was still a mass in the abdominal cavity to avoid misdiagnosis.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12893-021-01391-0","type":"journal-article","created":{"date-parts":[[2021,11,13]],"date-time":"2021-11-13T15:02:39Z","timestamp":1636815759000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["The diagnosis and treatment of retrograde intussusception: a single-centre experience"],"prefix":"10.1186","volume":"21","author":[{"given":"Bing","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dianming","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingkun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianxi","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifan","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,11,13]]},"reference":[{"issue":"11","key":"1391_CR1","doi-asserted-by":"publisher","first-page":"e018604","DOI":"10.1136\/bmjopen-2017-018604","volume":"7","author":"WL Guo","year":"2017","unstructured":"Guo WL, Hu ZC, Tan YL, Sheng M, Wang J. Risk factors for recurrent intussusception in children: a retrospective cohort study. BMJ Open. 2017;7(11):e018604.","journal-title":"BMJ Open"},{"issue":"10","key":"1391_CR2","doi-asserted-by":"publisher","first-page":"e1001330","DOI":"10.1371\/journal.pmed.1001330","volume":"9","author":"MM Patel","year":"2012","unstructured":"Patel MM, Clark AD, Sanderson CF, Tate J, Parashar UD. Removing the age restrictions for rotavirus vaccination: a benefit-risk modeling analysis. PLoS Med. 2012;9(10):e1001330.","journal-title":"PLoS Med"},{"key":"1391_CR3","doi-asserted-by":"crossref","unstructured":"Nylund CM, Denson LA, Noel JM. Bacterial enteritis as a risk factor for childhood intussusception: a retrospective cohort study. J Pediatr. 2010;156(5):761\u20135.","DOI":"10.1016\/j.jpeds.2009.11.026"},{"key":"1391_CR4","doi-asserted-by":"crossref","unstructured":"Groper MJ. Retrograde enteric intussusception. Ann Surg. 1940;112(3):344\u201351.","DOI":"10.1097\/00000658-194009000-00003"},{"issue":"699","key":"1391_CR5","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1136\/pgmj.60.699.75","volume":"60","author":"A Mitra","year":"1984","unstructured":"Mitra A, Roth RN. Retrograde ileo-ileal intussusception. Postgrad Med J. 1984;60(699):75.","journal-title":"Postgrad Med J"},{"issue":"5","key":"1391_CR6","doi-asserted-by":"publisher","first-page":"2204","DOI":"10.1007\/s00464-019-07009-0","volume":"34","author":"G Orthopoulos","year":"2020","unstructured":"Orthopoulos G, Grant HM, Sharma P, Thompson E, Romanelli JR. S054: incidence and management of jejunojejunal intussusception after Roux-en-Y gastric bypass: a large case series. Surg Endosc. 2020;34(5):2204\u201310.","journal-title":"Surg Endosc"},{"issue":"Suppl 1","key":"1391_CR7","doi-asserted-by":"publisher","first-page":"E262","DOI":"10.1055\/s-2007-966579","volume":"39","author":"L Pelosof","year":"2007","unstructured":"Pelosof L, Ringold DA, Kuo E, Bhalla S, Whinney R, Zuckerman GR. Retrograde jejunogastric intussusception caused by a migrated gastrostomy tube. Endoscopy. 2007;39(Suppl 1):E262-263.","journal-title":"Endoscopy"},{"issue":"12","key":"1391_CR8","doi-asserted-by":"publisher","first-page":"e13","DOI":"10.1016\/j.jpedsurg.2006.08.044","volume":"41","author":"CJ Humbyrd","year":"2006","unstructured":"Humbyrd CJ, Baril DT, Dolgin SE. Postoperative retrograde intussusception in an infant: a rare occurrence. J Pediatr Surg. 2006;41(12):e13\u20135.","journal-title":"J Pediatr Surg"},{"key":"1391_CR9","doi-asserted-by":"crossref","unstructured":"Maddox F. Orthograde and retrograde intussusception. Br Med J. 1954;1(4869):1022.","DOI":"10.1136\/bmj.1.4869.1022"},{"issue":"12","key":"1391_CR10","doi-asserted-by":"publisher","first-page":"1659","DOI":"10.7863\/jum.2004.23.12.1659","volume":"23","author":"A Kazez","year":"2004","unstructured":"Kazez A, Ozel SK, Kocakoc E, Kiris A. Double intussusception in a child: the triple-circle sign. J Ultrasound Med. 2004;23(12):1659\u201361.","journal-title":"J Ultrasound Med"},{"key":"1391_CR11","doi-asserted-by":"publisher","DOI":"10.1136\/bcr.08.2010.3294","author":"A Pandey","year":"2011","unstructured":"Pandey A, Rawat JD, Wakhlu A, Kureel SN, Gopal SC. Simultaneous occurrence of jejuno-jejunal and ileo-ileal intussusception in a child: a rare occurrence. BMJ Case Rep. 2011.\u00a0https:\/\/doi.org\/10.1136\/bcr.08.2010.3294.","journal-title":"Case Rep"},{"issue":"3","key":"1391_CR12","doi-asserted-by":"publisher","first-page":"261","DOI":"10.4103\/0189-6725.137338","volume":"11","author":"T Takahashi","year":"2014","unstructured":"Takahashi T, Miyano G, Kayano H, Lane GJ, Arakawa A, Yamataka A. A child with colo-colonic intussusception due to a large colonic polyp: case report and literature review. Afr J Paediatr Surg. 2014;11(3):261\u20133.","journal-title":"Afr J Paediatr Surg"},{"issue":"1","key":"1391_CR13","doi-asserted-by":"publisher","first-page":"e17","DOI":"10.1016\/j.jpedsurg.2008.10.037","volume":"44","author":"G Soccorso","year":"2009","unstructured":"Soccorso G, Puls F, Richards C, Pringle H, Nour S. A ganglioneuroma of the sigmoid colon presenting as leading point of intussusception in a child: a case report. J Pediatr Surg. 2009;44(1):e17-20.","journal-title":"J Pediatr Surg"},{"issue":"11","key":"1391_CR14","doi-asserted-by":"publisher","first-page":"1195","DOI":"10.1016\/S0022-3468(89)80119-8","volume":"24","author":"RD Fildes","year":"1989","unstructured":"Fildes RD, Springate JE, Jewett T, O\u2019Shea MM, Feld LG. Colonic intussusception secondary to a calcium phosphate bezoar in a child receiving calcium carbonat e for hyperphosphatemia. J Pediatr Surg. 1989;24(11):1195\u20137.","journal-title":"J Pediatr Surg"},{"key":"1391_CR15","doi-asserted-by":"crossref","unstructured":"Dubinsky MC, Deslandres C, Patriquin H, Seidman EG. Pneumatosis intestinalis and colocolic intussusception complicating Crohn's disease. J Pediatr Gastroenterol Nutr. 2000;30(1):96\u20138.","DOI":"10.1097\/00005176-200001000-00025"},{"issue":"2","key":"1391_CR16","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1007\/s00247-006-0381-1","volume":"37","author":"FA Justice","year":"2007","unstructured":"Justice FA, de Campo M, Liem NT, Son TN, Ninh TP, Bines JE. Accuracy of ultrasonography for the diagnosis of intussusception in infants in Vietnam. Pediatr Radiol. 2007;37(2):195\u20139.","journal-title":"Pediatr Radiol"},{"key":"1391_CR17","doi-asserted-by":"crossref","unstructured":"Takai A, Hasegawa T, Furukawa T, Tajiri T,Hosoi H.Ultrasonographic findings of multiple intussusception in an extremely preterm infant. Arch Dis Child. 2019;104(5):488.","DOI":"10.1136\/archdischild-2018-314885"},{"key":"1391_CR18","doi-asserted-by":"crossref","unstructured":"Sanders LH, Newman MA. Antegrade and retrograde stanford type A intimal intussusception. Ann Thorac Surg. 2009;87(6):2003.","DOI":"10.1016\/j.athoracsur.2008.12.015"},{"key":"1391_CR19","unstructured":"Egbuchulem KI, Lawal TA, Nweke MC, Adeoye AO. A case of compound intussusceptions in a nigerian child - a rare finding in a common disease. Ann Ib Postgrad Med. 2017;15(1):57\u201360."},{"issue":"3","key":"1391_CR20","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1007\/s00464-014-3717-1","volume":"29","author":"CH Wei","year":"2015","unstructured":"Wei CH, Fu YW, Wang NL, Du YC, Sheu JC. Laparoscopy versus open surgery for idiopathic intussusception in children. Surg Endosc. 2015;29(3):668\u201372.","journal-title":"Surg Endosc"}],"container-title":["BMC Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12893-021-01391-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12893-021-01391-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12893-021-01391-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,13]],"date-time":"2021-11-13T15:03:23Z","timestamp":1636815803000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcsurg.biomedcentral.com\/articles\/10.1186\/s12893-021-01391-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,13]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["1391"],"URL":"https:\/\/doi.org\/10.1186\/s12893-021-01391-0","relation":{},"ISSN":["1471-2482"],"issn-type":[{"value":"1471-2482","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,13]]},"assertion":[{"value":"29 May 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 October 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 November 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the Medical Ethics Committee of Fujian Maternal and Children\u2019s Hospital, and the guardian of the child was informed about specimen collection procedures, examinations and project objectives; Informed consent was obtained from the guardians of all the patients. We confirm that all methods were performed in accordance with the relevant guidelines and regulations.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"398"}}