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This has led to an increase in the incidence of spinal metastases. The purpose of this study was to assess risk factors for wound-related complications after surgical stabilization of spinal metastases with a special focus on the effect of postoperative RT and its timing.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Patients who had been treated for metastatic spine disease by surgical stabilization followed by radiotherapy between 01\/2012 and 03\/2019 were included and a retrospective chart review was performed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Of 604 patients who underwent stabilizing surgery for spinal metastases, 237 patients (mean age 66\u00a0years, SD 11) with a mean follow-up of 11\u00a0months (SD 7) were eligible for further analysis. Forty-one patients (17.3%) had wound-related complications, 32 of them before and 9 after beginning of the RT. Revision surgery was necessary in 26 patients (11.0%). Body weight (p\u2009=\u20090.021), obesity (p\u2009=\u20090.018), ASA\u2009&gt;\u20092 (p\u2009=\u20090.001), and start of radiation therapy within 21\u00a0days after surgery (p\u2009=\u20090.047) were associated with an increased risk for wound complications. Patients with chemotherapy within 3\u00a0weeks of surgery (12%) were more likely to have a wound-related surgical revision (p\u2009=\u20090.031).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Body weight, obesity and ASA\u2009&gt;\u20092 were associated with an increased risk for wound complications. Patients with chemotherapy within 3\u00a0weeks of the surgery were more likely to have a wound-related revision surgery. Patients who had begun radiation therapy within 21\u00a0days after surgery were more likely to have a wound complication compared to patients who waited longer.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12893-021-01431-9","type":"journal-article","created":{"date-parts":[[2021,12,17]],"date-time":"2021-12-17T15:10:29Z","timestamp":1639753829000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Risk factors for wound-related complications after surgical stabilization of spinal metastases with a special focus on the effect of postoperative radiation therapy"],"prefix":"10.1186","volume":"21","author":[{"given":"Jan-Sven","family":"Jarvers","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian","family":"Lange","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Schiemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Pfr\u00e4nger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph-Eckhard","family":"Heyde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg","family":"Osterhoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,12,17]]},"reference":[{"key":"1431_CR1","doi-asserted-by":"publisher","DOI":"10.3171\/foc.2001.11.6.11","volume":"11","author":"WB Jacobs","year":"2001","unstructured":"Jacobs WB, Perrin RG. 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