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TUSSLP was compared with the transabdominal three-site laparoscopic pyloromyotomy (TATSLP) procedure.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Patients with HPS who underwent TUSSLP and TATSLP between January 2016 and September 2020 were assigned to group A and group B, respectively. The descriptive variables, perioperative clinical characteristics and postoperative follow-up results were retrospectively analyzed and compared between the 2 groups. The primary outcome of this study was the rate of switching to conventional pyloromyotomy.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Sixty-four patients were enrolled in this study. Of these patients, 29 (22 males, 7 females, 54.4\u2009\u00b1\u200922.6 days) who received TUSSLP were assigned to group A. The remaining 35 (28 males, 7 females, 54.5\u2009\u00b1\u200927.6 days) who received TATSLP were assigned to group B. The data of preoperative patient variables were comparable between the 2 groups (<jats:italic>P<\/jats:italic>\u2009&gt;\u20090.05). The mean operative time (ORT) was 28.1\u2009\u00b1\u20095.6\u00a0min in group A, which was not significantly different from 25.8\u2009\u00b1\u20093.1\u00a0min in group B (<jats:italic>P<\/jats:italic>\u2009=\u20090.25). The other perioperative features were not significantly different between the 2 groups (<jats:italic>P<\/jats:italic>\u2009&gt;\u20090.05). During follow-up (39.1\u2009\u00b1\u200914.7\u00a0m in group A and 35.4\u2009\u00b1\u200916.1\u00a0m in group B, <jats:italic>P<\/jats:italic>\u2009=\u20090.51), no significant difference was observed in the overall incidence of vomiting between the 2 groups (<jats:italic>P<\/jats:italic>\u2009=\u20090.26).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>TUSSLP is a feasible and reliable minimally invasive method for HPS. It has the advantages of an improved cosmetic appearance. The postoperative follow-up results of TUSSLP are comparable with those of TATSLP.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12893-022-01672-2","type":"journal-article","created":{"date-parts":[[2022,6,7]],"date-time":"2022-06-07T10:03:25Z","timestamp":1654596205000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Transumbilical single-site two incision laparoscopic pyloromyotomy for pediatric hypertrophic pyloric stenosis"],"prefix":"10.1186","volume":"22","author":[{"given":"Yi","family":"Ji","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqin","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhicheng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,6,7]]},"reference":[{"issue":"11","key":"1672_CR1","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1038\/nrgastro.2012.133","volume":"9","author":"B Peeters","year":"2012","unstructured":"Peeters B, Benninga MA, Hennekam RC. 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The study was conducted in accordance with the Declaration of Helsinki and Good Clinical Practice guidelines. Parents of the enrolled children were informed about the study upon admission and provided written informed consent.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent for publication of this study was obtained from the patients\u2019 parents. Copies of the signed informed consent forms are available for review by the Series Editor of BMC Pediatrics.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors have disclosed that they do not have any potential conflicts of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"218"}}