{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T16:29:57Z","timestamp":1782750597465,"version":"3.54.5"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T00:00:00Z","timestamp":1764979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T00:00:00Z","timestamp":1767830400000},"content-version":"vor","delay-in-days":33,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Surg"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Pineoblastoma, a highly aggressive embryonal tumor predominantly affecting the pediatric population, poses significant therapeutic challenges. Current treatment modalities typically involve a combination of surgical resection, chemotherapy, and radiotherapy. While the clinical presentation of pineoblastoma is well-documented, its association with other neurological conditions, particularly Chiari malformations, remains exceedingly rare.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case report<\/jats:title>\n                    <jats:p>This report presents a unique case of a 17-year-old male patient diagnosed with both pineoblastoma and Chiari type 1.5 malformation. The patient presented with headache as the sole complaint. Neurological examination revealed nystagmus, quadriparesis, restricted ocular motility in the right eye, and cerebellar signs including a positive Romberg test, dystonia, and dysmetria. Notably, the patient had no history of radiation exposure or known genetic predisposition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This case marks the initial reported occurrence of concurrently managing a Chiari malformation while surgically removing a pineal region tumor to create a wider and safer surgical corridor. Our combined approach allowed safe and effective tumor resection while optimizing surgical exposure. It may serve as a useful reference for surgeons facing similar complex pathologies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12893-025-03403-9","type":"journal-article","created":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T04:31:36Z","timestamp":1764995496000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Concurrent surgical management of pineoblastoma and Chiari type 1.5 malformation: a case report"],"prefix":"10.1186","volume":"26","author":[{"given":"H\u00fcseyin","family":"Yi\u011fit","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulkerim","family":"G\u00f6ko\u011flu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,6]]},"reference":[{"issue":"3","key":"3403_CR1","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1007\/s11060-021-03919-z","volume":"156","author":"MJ Shepard","year":"2022","unstructured":"Shepard MJ, et al. Long term outcomes following surgery for pineal region tumors. J Neurooncol. 2022;156(3):491\u20138.","journal-title":"J Neurooncol"},{"key":"3403_CR2","doi-asserted-by":"publisher","unstructured":"Huang LT, Zhou Q, Tong X. Treatment of Pineal Region Lesions in Children. J Craniofac Surg. 2024;35(1):e60\u20136. https:\/\/doi.org\/10.1097\/SCS.0000000000009846.","DOI":"10.1097\/SCS.0000000000009846."},{"key":"3403_CR3","doi-asserted-by":"publisher","unstructured":"Muthukumar N. Hydrocephalus Associated with Posterior Fossa Tumors: How to Manage Effectively? Neurol India. 2021;69(Supplement):S342-9. https:\/\/doi.org\/10.4103\/0028-3886.332260.","DOI":"10.4103\/0028-3886.332260"},{"issue":"3","key":"3403_CR4","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/j.nec.2011.05.001","volume":"22","author":"MC Tate","year":"2011","unstructured":"Tate MC, Rutkowski MJ, Parsa AT. Contemporary management of Pineoblastoma. Neurosurg Clin N Am. 2011;22(3):409\u201312. ix.","journal-title":"Neurosurg Clin N Am"},{"issue":"2","key":"3403_CR5","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1007\/s00401-007-0243-4","volume":"114","author":"DN Louis","year":"2007","unstructured":"Louis DN, et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007;114(2):97\u2013109.","journal-title":"Acta Neuropathol"},{"key":"3403_CR6","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12144626","author":"J Sahuquillo","year":"2023","unstructured":"Sahuquillo J, et al. A critical update of the classification of Chiari and Chiari-like malformations. J Clin Med. 2023. https:\/\/doi.org\/10.3390\/jcm12144626.","journal-title":"J Clin Med"},{"key":"3403_CR7","doi-asserted-by":"publisher","unstructured":"Kim IK, Wang KC, Kim IO, Cho BK. Chiari 1.5 malformation: an advanced form of Chiari I malformation. J Korean Neurosurg Soc. 2010;48(4):375\u20139. https:\/\/doi.org\/10.3340\/jkns.2010.48.4.375.","DOI":"10.3340\/jkns.2010.48.4.375"},{"issue":"2 Suppl","key":"3403_CR8","first-page":"179","volume":"101","author":"RS Tubbs","year":"2004","unstructured":"Tubbs RS, et al. A critical analysis of the Chiari 1.5 malformation. J Neurosurg. 2004;101(2 Suppl):179\u201383.","journal-title":"J Neurosurg"},{"key":"3403_CR9","doi-asserted-by":"publisher","unstructured":"Sharma H, Treiber JM, Bauer DF. Chiari 1 and Hydrocephalus - A Review. Neurol India. 2021;69(Supplement):S362\u20136. https:\/\/doi.org\/10.4103\/0028-3886.332274.","DOI":"10.4103\/0028-3886.332274"},{"key":"3403_CR10","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13071547","author":"G Favero","year":"2021","unstructured":"Favero G, Bonomini F, Rezzani R. Pineal gland tumors: a review. Cancers (Basel). 2021. https:\/\/doi.org\/10.3390\/cancers13071547.","journal-title":"Cancers (Basel)"},{"issue":"1","key":"3403_CR11","doi-asserted-by":"publisher","first-page":"188","DOI":"10.3171\/2017.4.JNS162805","volume":"129","author":"S Matsuo","year":"2018","unstructured":"Matsuo S, et al. Prevention of postoperative visual field defect after the occipital transtentorial approach: anatomical study. J Neurosurg. 2018;129(1):188\u201397.","journal-title":"J Neurosurg"},{"issue":"S4","key":"3403_CR12","first-page":"e2021351","volume":"92","author":"S Anetsberger","year":"2022","unstructured":"Anetsberger S, et al. Interhemispheric approach. Acta Biomed Atenei Parmensis. 2022;92(S4):e2021351.","journal-title":"Acta Biomed Atenei Parmensis"},{"issue":"2","key":"3403_CR13","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1055\/a-2018-4745","volume":"85","author":"DD Dang","year":"2024","unstructured":"Dang DD, et al. Anatomical Step-by-Step dissection of midline suboccipital approaches to the fourth ventricle for trainees: surgical anatomy of the Telovelar, Transvermian, and superior transvelar Routes, surgical Principles, and illustrative cases. 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