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The aim of this randomised, controlled, single-blind study was to evaluate a peri-operative physical training programme in patients undergoing oesophageal cancer resection surgery due to cancer of the oesophagus or the gastro-oesophageal junction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>One hundred patients scheduled to undergo Ivor Lewis oesophagectomy in one of five university hospitals in Sweden were randomised to a control group or intervention including respiratory muscle training, strength training, and increased physical activity before surgery and up to 3 months postoperatively. Outcome measures were physical capacity, respiratory muscle strength, spirometry, grip strength, and chest mobility. Questionnaires regarding physical activity and function, recovery, and health-related quality of life were completed at inclusion and 3 and 12 months postoperatively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We did not find significant differences between the groups in physical capacity during follow-up. However, the intervention group performed significantly better than the control group in maximal inspiratory pressure (\u039418%), maximal expiratory pressure (\u039418%), and peak expiratory flow (\u039412%) 3 months postoperatively (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Patients in the intervention group also developed fewer pulmonary complications (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.019). We did not find differences between the groups in recovery or health-related quality of life.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A peri-operative training intervention including respiratory muscle training had a positive impact on respiratory function and pulmonary complications. However, neither strength training nor increased physical activity had any effects. Thus, respiratory muscle training may be offered as a peri-operative regimen in oesophageal cancer surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration<\/jats:title>\n                    <jats:p>FoU i VGR 238,651 (Released Dec 15, 2017), Clinical Trials NCT03452319 (Released Feb 18, 2018).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12893-025-03416-4","type":"journal-article","created":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T00:45:51Z","timestamp":1765413951000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Positive effects of a perioperative training intervention in Ivor Lewis oesophageal surgery: a randomised, controlled multicentre trial"],"prefix":"10.1186","volume":"26","author":[{"given":"Monika","family":"Fagevik Ols\u00e9n","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"L\u00f6thgren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrika","family":"Tr\u00f6lle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elina","family":"Elf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophie","family":"Toomv\u00e4li-Petersson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Hermansson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Hammerlid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrika","family":"Smedh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,12,11]]},"reference":[{"key":"3416_CR1","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1002\/crt2.9","volume":"5","author":"J Persson","year":"2020","unstructured":"Persson J, Fagevik Ols\u00e9n M, Iresj\u00f6 B-M, Smedh U. 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