{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T17:53:37Z","timestamp":1781632417675,"version":"3.54.5"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T00:00:00Z","timestamp":1769385600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T00:00:00Z","timestamp":1771286400000},"content-version":"vor","delay-in-days":22,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Clinical Research Innovation Fund of The 925th Hospital of PLA Joint Logistic Support Force","award":["YJKT2023-07"],"award-info":[{"award-number":["YJKT2023-07"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Surg"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Despite cultural preferences for organ preservation in East Asia, choledochoscopic gallbladder-preserving surgery (CGPS) remains controversial given high recurrence rates. This study objectively quantified the increased technical complexity of laparoscopic cholecystectomy (LC) for recurrent cholecystolithiasis after prior CGPS using the Tokyo Guidelines 2018 (TG18).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In this propensity-matched study (1:1,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009220) conducted between 2020 and 2025, patients requiring LC due to recurrent cholecystolithiasis after prior CGPS were compared with patients with primary cholecystolithiasis undergoing LC. Investigators matched groups for TG18 severity grading, BMI, and biliary anomalies. Two blinded surgeons assessed the intraoperative findings using TG18 Delphi scoring (7-point scale). Primary outcomes included difficulty scores, critical view of safety (CVS) achievement, and bile duct injury.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The CGPS group demonstrated significantly higher median TG18 scores (34 [IQR 30\u201339] vs. 21 [18\u201324]; adjusted mean difference: \u0394 14.0 points, 95% CI: 11.2\u201316.8;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), primarily due to fibrotic adhesions: Calot\u2019s triangle dense fibrosis (49.1% vs. 6.4%), partial scarring (21.8% vs. 0.9%), and diffuse scarring (15.5% vs. 0%; all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Surgeons achieved CVS less frequently in the CGPS group (83.6% vs. 98.2%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). TG18 scores\u2009&gt;\u200925 predicted a fivefold increased conversion risk (aOR\u2009=\u20094.9, 95% CI: 2.3\u201310.6).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Prior CGPS induces irreversible fibrosis that significantly increases reoperative difficulty (\u0394 14 TG18 points), highlighting the need for careful patient selection in organ-preserving procedures. Definitive management with primary cholecystectomy remains the gold standard.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12893-026-03525-8","type":"journal-article","created":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T04:03:42Z","timestamp":1769400222000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Laparoscopic cholecystectomy after gallbladder preservation: TG18 Delphi score quantifies surgical difficulty"],"prefix":"10.1186","volume":"26","author":[{"given":"Juxian","family":"Song","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianlong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weikun","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hulin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,1,26]]},"reference":[{"key":"3525_CR1","doi-asserted-by":"crossref","unstructured":"Brunt LM, Deziel DJ, Telem DA, Strasberg SM, Aggarwal R, Asbun H et al. 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