{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T19:13:27Z","timestamp":1792523607771,"version":"4.5.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Urol"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s12894-017-0304-5","type":"journal-article","created":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T07:12:34Z","timestamp":1512544354000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Emerging concepts and spectrum of renal injury following Intravesical BCG for non-muscle invasive bladder cancer"],"prefix":"10.1186","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8384-5097","authenticated-orcid":false,"given":"Azharuddin","family":"Mohammed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zubair","family":"Arastu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,12,6]]},"reference":[{"issue":"6","key":"304_CR1","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1093\/ckj\/sfv103","volume":"8","author":"BW Gillespie","year":"2015","unstructured":"Gillespie BW, Morgenstern H, Hedgeman E, et al. Nephrology care prior to end-stage renal disease and outcomes among new ESRD patients in the USA. Clin Kidney J. 2015;8(6):772\u201380.","journal-title":"Clin Kidney J"},{"issue":"10","key":"304_CR2","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/nrurol.2015.232","volume":"12","author":"I Lucca","year":"2015","unstructured":"Lucca I, Klatte T, Fajkovic H, de Martino M, Shariat SF. Gender differences in incidence and outcomes of urothelial and kidney cancer. Nat Rev Urol. 2015;12(10):585\u2013592.","journal-title":"Nat Rev Urol"},{"issue":"4","key":"304_CR3","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1038\/nrurol.2015.58","volume":"12","author":"AM Kamat","year":"2015","unstructured":"Kamat AM, Flaig TW, Grossman HB, Konety B, Lamm D, O'Donnell MA, et al. Expert consensus document: consensus statement on best practice management regarding the use of intravesical immunotherapy with BCG for bladder cancer. Nat Rev Urol. 2015;12(4):225\u201335.","journal-title":"Nat Rev Urol."},{"key":"304_CR4","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1111\/bju.12468","volume":"113","author":"GB Boustead","year":"2014","unstructured":"Boustead GB, Fowler S, Swamy R, et al. Stage, grade and pathological cancer in the UK: British Association of Urological Surgeons (BAUS) urological tumour registry. BJU Int. 2014;113:924\u201330.","journal-title":"BJU Int"},{"issue":"2","key":"304_CR5","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/S0022-5347(17)58737-6","volume":"116","author":"A Morales","year":"1976","unstructured":"Morales A, Eidinger D, Bruce AW. Intracavitary bacillus Calmette-Guerin in the treatment of superficial bladder tumors. J Urol. 1976;116(2):180\u20133.","journal-title":"J Urol"},{"issue":"Suppl 3","key":"304_CR6","doi-asserted-by":"crossref","first-page":"S86","DOI":"10.1086\/314064","volume":"31","author":"DL Lamm","year":"2000","unstructured":"Lamm DL. Efficacy and safety of bacille Calmette-Gu\u00e9rin immunotherapy in superficial bladder cancer. Clin Infect Dis. 2000;31(Suppl 3):S86\u201390.","journal-title":"Clin Infect Dis"},{"issue":"3","key":"304_CR7","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/nrurol.2014.15","volume":"11","author":"G Redelman-Sidi","year":"2014","unstructured":"Redelman-Sidi G, Glickman MS, Bochner BH. The mechanism of action of BCG therapy for bladder cancer--a current perspective. Nat Rev Urol. 2014;11(3):153\u201362.","journal-title":"Nat Rev Urol"},{"issue":"11","key":"304_CR8","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1345\/aph.19329","volume":"34","author":"H Peyri\u00e8re","year":"2000","unstructured":"Peyri\u00e8re H, Klouche K, B\u00e9raud JJ, Blayac JP, Hillaire-Buys D. Fatal systemic reaction after multiple doses of intravesical bacillus Calmette-Gu\u00e9rin for polyposis. Ann Pharmacother. 2000;34(11):1279\u201382.","journal-title":"Ann Pharmacother"},{"key":"304_CR9","unstructured":"Vaccineshoppe.com. TheraCys. Full Prescribing Information. [Online]. 2015. Available at: \nhttps:\/\/www.vaccineshoppe.com\/image.cfm?doc_id=12635&image_type=product_pdf"},{"issue":"2","key":"304_CR10","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1086\/344908","volume":"36","author":"OY Gonzalez","year":"2003","unstructured":"Gonzalez OY, Musher DM, Brar I, Furgeson S, Boktour MR, Septimus EJ, et al. Spectrum of bacille Calmette-Gu\u00e9rin (BCG) infection after intravesical BCG immunotherapy. Clin Infect Dis. 2003;36(2):140\u20138.","journal-title":"Clin Infect Dis"},{"key":"304_CR11","doi-asserted-by":"crossref","first-page":"71","DOI":"10.4137\/CCRep.S39904","volume":"9","author":"F Elzein","year":"2016","unstructured":"Elzein F, Albogami N, Saad M, El Tayeb N, Alghamdi A, Elyamany G. Disseminated Mycobacterium Bovis infection complicating Intravesical BCG instillation for the treatment of superficial transitional cell carcinoma of the bladder. Clin Med Insights Case Rep. 2016;9:71\u20133.","journal-title":"Clin Med Insights Case Rep"},{"key":"304_CR12","doi-asserted-by":"crossref","unstructured":"Mat O, Kada R, Phillipart P, et al. Late and reversible kidney-lung failure after intra-bladder BCG therapy. Open Journal of Nephrology. 2013:120\u20133.","DOI":"10.4236\/ojneph.2013.33022"},{"issue":"2","key":"304_CR13","first-page":"127","volume":"54","author":"T Hirayama","year":"2008","unstructured":"Hirayama T, Matsumoto K, Tsuboi T, Fujita T, Satoh T, Iwamura M, et al. Anaphylactoid purpura after intravesical therapy using bacillus Calmette-Guerin for superficial bladder cancer. Hinyokika Kiyo. 2008;54(2):127\u20139.","journal-title":"Hinyokika Kiyo."},{"issue":"4","key":"304_CR14","first-page":"281","volume":"47","author":"N Shimasaki","year":"2001","unstructured":"Shimasaki N, Yamasaki I, Kamada M, Syuin T. Two cases of successful treatments with steroid for local and systemic hypersensitivity reaction following intravesical instillation of bacillus Calmette-Guerin. Hinyokika Kiyo. 2001;47(4):281\u20134.","journal-title":"Hinyokika Kiyo"},{"issue":"3","key":"304_CR15","doi-asserted-by":"crossref","first-page":"259","DOI":"10.4103\/0970-1591.156921","volume":"31","author":"S Bhat","year":"2015","unstructured":"Bhat S, Srinivasa Y, Paul F. Asymptomatic renal BCG granulomatosis: an unusual complication of intravesical BCG therapy for carcinoma urinary bladder. Indian J Urol. 2015;31(3):259\u201361.","journal-title":"Indian J Urol"},{"issue":"3\u20134","key":"304_CR16","doi-asserted-by":"crossref","first-page":"E200","DOI":"10.5489\/cuaj.2664","volume":"9","author":"T Al-Qaoud","year":"2015","unstructured":"Al-Qaoud T, Brimo F, Aprikian AG, Andonian S. BCG-related renal granulomas managed conservatively: a case series. Can Urol Assoc J. 2015;9(3\u20134):E200\u20133.","journal-title":"Can Urol Assoc J"},{"key":"304_CR17","doi-asserted-by":"crossref","first-page":"541","DOI":"10.2169\/internalmedicine.56.7494","volume":"56","author":"H Tsukada","year":"2017","unstructured":"Tsukada H, Miyakawa H. Henoch Sch\u00f6nlein Purpura nephritis associated with Intravesical bacillus Calmette-Guerin (BCG) therapy. Intern Med. 2017;56:541\u20134.","journal-title":"Intern Med"},{"issue":"2","key":"304_CR18","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1080\/08860220601098961","volume":"29","author":"NP Singh","year":"2007","unstructured":"Singh NP, Prakash A, Kubba S, Ganguli A, Agarwal SK, Dinda AK, et al. Nephrotic syndrome as a complication of intravesical BCG treatment of transitional cell carcinoma of urinary bladder. Ren Fail. 2007;29(2):227\u20139.","journal-title":"Ren Fail"},{"issue":"3","key":"304_CR19","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/S0022-5347(17)37316-0","volume":"147","author":"DL Lamm","year":"1992","unstructured":"Lamm DL, van der Meijden PM, Morales A, Brosman SA, Catalona WJ, Herr HW, et al. Incidence and treatment of complications of bacillus Calmette-Guerin intravesical therapy in superficial bladder cancer. J Urol. 1992;147(3):596\u2013600.","journal-title":"J Urol"},{"issue":"4","key":"304_CR20","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/j.urology.2011.12.024","volume":"79","author":"BT Ristau","year":"2012","unstructured":"Ristau BT, Tomaszewski JJ, Ost MC. Upper tract urothelial carcinoma: current treatment and outcomes. Urology. 2012;79(4):749\u201356.","journal-title":"Urology"},{"issue":"6","key":"304_CR21","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1159\/000168368","volume":"11","author":"A Modesto","year":"1991","unstructured":"Modesto A, Marty L, Suc JM, Kleinknecht D, de Fr\u00e9mont JF, Marsepoil T, et al. Renal complications of intravesical bacillus Calmette-Gu\u00e9rin therapy. Am J Nephrol. 1991;11(6):501\u20134.","journal-title":"Am J Nephrol"},{"issue":"4","key":"304_CR22","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1093\/ndt\/gfh688","volume":"20","author":"A Fry","year":"2005","unstructured":"Fry A, Saleemi A, Griffiths M, Farrington K. Acute renal failure following intravesical bacille Calmette-Gu\u00e9rin chemotherapy for superficial carcinoma of the bladder. Nephrol Dial Transplant. 2005;20(4):849\u201350.","journal-title":"Nephrol Dial Transplant"},{"issue":"5","key":"304_CR23","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1093\/ndt\/gfk071","volume":"21","author":"SE Kennedy","year":"2006","unstructured":"Kennedy SE, Shrikanth S, Charlesworth JA. Acute granulomatous tubulointerstitial nephritis caused by intravesical BCG. Nephrol Dial Transplant. 2006;21(5):1427\u20139.","journal-title":"Nephrol Dial Transplant"},{"issue":"3","key":"304_CR24","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1007\/s10157-007-0483-6","volume":"11","author":"MJ Manzanera Escribano","year":"2007","unstructured":"Manzanera Escribano MJ, Morales Ruiz E, Odriozola Grijalba M, Gutierrez Mart\u00ednez E, Rodriguez Antol\u00edn A, Praga TM. Acute renal failure due to interstitial nephritis after intravesical instillation of BCG. Clin Exp Nephrol. 2007;11(3):238\u201340.","journal-title":"Clin Exp Nephrol"},{"issue":"2","key":"304_CR25","first-page":"109","volume":"46","author":"N Numao","year":"2000","unstructured":"Numao N, Goto S, Suzuki S. A case of renal tuberculosis following bacillus Calmette-Guerin instillation therapy for bladder cancer. Hinyokika Kiyo. 2000;46(2):109\u201311.","journal-title":"Hinyokika Kiyo"}],"container-title":["BMC Urology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12894-017-0304-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T07:12:55Z","timestamp":1512544375000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcurol.biomedcentral.com\/articles\/10.1186\/s12894-017-0304-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["304"],"URL":"https:\/\/doi.org\/10.1186\/s12894-017-0304-5","relation":{},"ISSN":["1471-2490"],"issn-type":[{"value":"1471-2490","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12]]},"article-number":"114"}}