{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T12:29:54Z","timestamp":1763468994043,"version":"3.37.3"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T00:00:00Z","timestamp":1725408000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T00:00:00Z","timestamp":1725408000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Urol"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Patients undergoing treatment for prostate cancer may develop lymphoedema of the midline region. This has a substantial impact on a patient\u2019s quality of life and its diagnosis is often delayed or missed. Therefore, the purpose of this study is to compare the characteristics of patients with leg and midline lymphoedema to patients with only leg lymphoedema.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We retrospectively collected patient-, cancer-, lymphoedema- and lymphoedema treatment-related data of 109 men with lymphoedema after treatment for prostate cancer. First, 42 characteristics were compared between both groups. Second, factors predicting presence of midline lymphoedema were explored by multivariable analyses.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The mean age of the patients with lymphoedema was 68 ( \u00b17) years and mean BMI is 28 (\u00b14) kg\/m<jats:sup>2<\/jats:sup>. Median duration of lymphoedema before the first consultation was 27 (9;55) months. Based on univariable analyses, patients with leg and midline lymphoedema had more frequently upper leg lymphoedema (89% (31\/35) vs. 69% (51\/74), <jats:italic>p<\/jats:italic>\u2009=\u20090.026), skin fibrosis (34% (12\/35) vs. 16% (12\/74), <jats:italic>p<\/jats:italic>\u2009=\u20090.034) and lymphatic reconstructive surgery (9% (3\/35) vs. 0% (0\/71), <jats:italic>p<\/jats:italic>\u2009=\u20090.020) than patients with only leg lymphoedema. Additionally, patients with leg and midline lymphoedema reported less frequently lower leg lymphoedema (77% (27\/35) vs. 95% (70\/74), <jats:italic>p<\/jats:italic>\u2009=\u20090.007). Based on the multivariable analysis, not having lower leg lymphoedema, skin fibrosis, performing self-bandaging and self-manual lymphatic drainage appear to be predictors for having midline lymphoedema.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>If patients with lymphoedema after prostate cancer do not have lower leg lymphoedema, have skin fibrosis, perform self-bandaging or self-manual lymphatic drainage, they possibly have midline lymphoedema.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12894-024-01533-5","type":"journal-article","created":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T05:02:37Z","timestamp":1725426157000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Characteristics of lymphoedema, in particular midline lymphoedema, after treatment for prostate cancer: a retrospective study"],"prefix":"10.1186","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2726-2361","authenticated-orcid":false,"given":"Charlotte","family":"Van Calster","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3157-7115","authenticated-orcid":false,"given":"Wouter","family":"Everaerts","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3617-6334","authenticated-orcid":false,"given":"Inge","family":"Geraerts","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6771-2836","authenticated-orcid":false,"given":"An","family":"De Groef","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3826-5464","authenticated-orcid":false,"given":"An-Kathleen","family":"Heroes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5719-6169","authenticated-orcid":false,"given":"Tessa","family":"De Vrieze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6044-9243","authenticated-orcid":false,"given":"Ceyhun","family":"Alar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8117-7080","authenticated-orcid":false,"given":"Nele","family":"Devoogdt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,9,4]]},"reference":[{"key":"1533_CR1","doi-asserted-by":"publisher","unstructured":"Sung H, et al. 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Sup 2021;30(12):1\u201340.","DOI":"10.12968\/bjon.2021.30.9.S18"}],"container-title":["BMC Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12894-024-01533-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12894-024-01533-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12894-024-01533-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T05:05:10Z","timestamp":1725426310000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcurol.biomedcentral.com\/articles\/10.1186\/s12894-024-01533-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,4]]},"references-count":20,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["1533"],"URL":"https:\/\/doi.org\/10.1186\/s12894-024-01533-5","relation":{},"ISSN":["1471-2490"],"issn-type":[{"type":"electronic","value":"1471-2490"}],"subject":[],"published":{"date-parts":[[2024,9,4]]},"assertion":[{"value":"17 January 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 July 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 September 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This retrospective study has obtained approval from the Ethical Committee of UZ\/ KU Leuven (S66167). Information obligation is met through UZ Leuven privacy policy, Clinical research brochure & via Mynexushealth. Data for the study was obtained from electronic patient records at UZ Leuven hospital. Conducting scientific research is deemed a task of general public interest, serving as the legal foundation for the designated role of UZ Leuven as a university hospital affiliated with KU Leuven. Since both UZ Leuven and KU Leuven fall under the same legal entity, the sharing of personal information is permitted and governed by the privacy statements of UZ Leuven. These statements explicitly inform patients that any medical information collected during their stay, consultation, or treatment may be utilized in the context of non-commercial academic scientific research without the necessity of obtaining informed consent (as per Article 9, \u00a7\u00a03 of the UZ Leuven privacy regulations for patients). , .","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"192"}}