{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T08:49:43Z","timestamp":1768294183294,"version":"3.49.0"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T00:00:00Z","timestamp":1723593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T00:00:00Z","timestamp":1723593600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Urol"],"DOI":"10.1186\/s12894-024-01557-x","type":"journal-article","created":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T02:02:01Z","timestamp":1723600921000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Can the SIARI score be used at initial admission to predict testes involvement in patients with fournier\u2019s gangrene; a single-centre, retrospective study"],"prefix":"10.1186","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5132-7447","authenticated-orcid":false,"given":"Anil","family":"Erdik","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1373-5239","authenticated-orcid":false,"given":"Kemal","family":"Demirhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0824-3926","authenticated-orcid":false,"given":"Haci Ibrahim","family":"Cimen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6398-8410","authenticated-orcid":false,"given":"Yavuz Tarik","family":"Atik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0873-0000","authenticated-orcid":false,"given":"Deniz","family":"Gul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1053-3551","authenticated-orcid":false,"given":"Osman","family":"Kose","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8904-1612","authenticated-orcid":false,"given":"Hasan Salih","family":"Saglam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,8,14]]},"reference":[{"issue":"8","key":"1557_CR1","doi-asserted-by":"publisher","first-page":"1303","DOI":"10.1007\/s11255-019-02188-0","volume":"51","author":"I Selvi","year":"2019","unstructured":"Selvi I, Aykac A, Baran O, Burlukkara S, Ozok U, Sunay MM. A different perspective for morbidity related to Fournier\u2019s gangrene: which scoring system is more reliable to predict requirement of skin graft and flaps in survivors of Fournier\u2019s gangrene? Int Urol Nephrol. 2019;51(8):1303\u201311. https:\/\/doi.org\/10.1007\/s11255-019-02188-0.","journal-title":"Int Urol Nephrol"},{"key":"1557_CR2","doi-asserted-by":"publisher","unstructured":"Ozkan OF, et al. Fournier\u2019s gangrene current approaches. Int Wound J. Oct. 2016;13(5):713\u20136. https:\/\/doi.org\/10.1111\/iwj.12357.","DOI":"10.1111\/iwj.12357"},{"key":"1557_CR3","doi-asserted-by":"publisher","unstructured":"Y\u00fccel M, \u00d6zpek A, Ba\u00feak F, K\u00fdl\u00fd\u00e7 A, \u00dcnal E, Y\u00fcksekda\u00f0 S, Acar A, Ba\u00fe G. Fournier\u2019s gangrene: A retrospective analysis of 25 patients. Turkish Journal of Trauma and Emergency Surgery. 2017 Sep 1;23(5):400\u20134. https:\/\/doi.org\/10.5505\/tjtes.2017.01678.","DOI":"10.5505\/tjtes.2017.01678"},{"key":"1557_CR4","doi-asserted-by":"publisher","first-page":"23","DOI":"10.11604\/pamj.2021.38.23.25863","volume":"38","author":"F Boughanmi","year":"2021","unstructured":"Boughanmi F, Ennaceur F, Korbi I, Chaka A, Noomen F, Zouari K. Fournier\u2019s gangrene: its management remains a challenge. Pan Afr Med J. 2021;38:23. https:\/\/doi.org\/10.11604\/pamj.2021.38.23.25863.","journal-title":"Pan Afr Med J"},{"key":"1557_CR5","doi-asserted-by":"publisher","unstructured":"Wong CH, Khin LW, Heng KS, Tan KC, Low CO. The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections. Critical care medicine. 2004 Jul 1;32(7):1535\u201341. https:\/\/doi.org\/10.1097\/01.ccm.0000129486.35458.7d.","DOI":"10.1097\/01.ccm.0000129486.35458.7d"},{"key":"1557_CR6","doi-asserted-by":"publisher","unstructured":"Cribb BI, Wang MTM, Kulasegaran S, Gamble GD, MacCormick AD. The SIARI Score: A Novel Decision Support Tool Outperforms LRINEC Score in Necrotizing Fasciitis. World J. Surg. Oct. 2019;43(10):2393\u2013400. https:\/\/doi.org\/10.1007\/s00268-019-05061-4.","DOI":"10.1007\/s00268-019-05061-4"},{"key":"1557_CR7","doi-asserted-by":"publisher","unstructured":"Sarkis P, Farran F, Khoury R, Kamel G, Nemr E, Biajini J, Merheje S. [Fournier\u2019s gangrene: a review of the recent literature]. Prog. en Urol. J. l\u2019Association Fr. d\u2019urologie la Soc. Fr. d\u2019urologie, Feb. 2009;19(2):75\u201384. https:\/\/doi.org\/10.1016\/j.purol.2008.09.050.","DOI":"10.1016\/j.purol.2008.09.050"},{"key":"1557_CR8","doi-asserted-by":"publisher","unstructured":"Sorensen MD, et al. Fournier\u2019s Gangrene: population based epidemiology and outcomes. J Urol. May 2009;181(5):2120\u20136. https:\/\/doi.org\/10.1016\/j.juro.2009.01.034.","DOI":"10.1016\/j.juro.2009.01.034"},{"issue":"10","key":"1557_CR9","doi-asserted-by":"publisher","first-page":"1024","DOI":"10.1016\/s0210-4806(08)73982-2","volume":"32","author":"J Medina Polo","year":"2008","unstructured":"Medina Polo J, Tejido S\u00e1nchez A, de la Rosa F, Kehrmann N, Felip Santamar\u00eda MB, Alvarez, Galvis OL. [Fournier gangrene: evaluation of prognostic factors in 90 patients]. Actas Urol Esp. 2008;32(10):1024\u201330. https:\/\/doi.org\/10.1016\/s0210-4806(08)73982-2.","journal-title":"Actas Urol Esp"},{"key":"1557_CR10","doi-asserted-by":"publisher","unstructured":"Vyas HG, Kumar A, Bhandari V, Kumar N, Jain A, Kumar R. Prospective evaluation of risk factors for mortality in patients of Fournier\u2019s gangrene: A single center experience. Indian J. Urol. Jul. 2013:29(3):161\u201365. https:\/\/doi.org\/10.4103\/0970-1591.117255.","DOI":"10.4103\/0970-1591.117255"},{"key":"1557_CR11","doi-asserted-by":"publisher","first-page":"942437","DOI":"10.5402\/2012\/942437","volume":"2012","author":"MN Mallikarjuna","year":"2012","unstructured":"Mallikarjuna MN, Vijayakumar A, Patil VS, Shivswamy BS. Fournier\u2019s Gangrene: current practices. ISRN Surg. 2012;2012:942437. https:\/\/doi.org\/10.5402\/2012\/942437.","journal-title":"ISRN Surg"},{"key":"1557_CR12","doi-asserted-by":"publisher","unstructured":"Benjelloun EB, et al. Fournier\u2019s gangrene: our experience with 50 patients and analysis of factors affecting mortality. World J Emerg Surg. Apr. 2013;8(1):13. https:\/\/doi.org\/10.1186\/1749-7922-8-13.","DOI":"10.1186\/1749-7922-8-13"},{"key":"1557_CR13","doi-asserted-by":"publisher","unstructured":"Czymek R, Schmidt A, Eckmann C, Bouchard R, Wulff B, Laubert T, Limmer S, Bruch H-P, Kujath P. Fournier\u2019s gangrene: vacuum-assisted closure versus conventional dressings. Am. J. Surg. Feb. 2009;197(2):168\u201376. https:\/\/doi.org\/10.1016\/j.amjsurg.2008.07.053.","DOI":"10.1016\/j.amjsurg.2008.07.053"},{"key":"1557_CR14","doi-asserted-by":"publisher","unstructured":"Shyam DC, Rapsang AG. Fournier\u2019s gangrene. Surgeon. Aug. 2013;11(4):222\u201332. https:\/\/doi.org\/10.1016\/j.surge.2013.02.001.","DOI":"10.1016\/j.surge.2013.02.001"},{"key":"1557_CR15","doi-asserted-by":"publisher","unstructured":"Ullah S, Khan M, Jan MAU. Fournier\u2019s gangrene: a dreadful disease. Surgeon. Jun. 2009;7(3):138\u201342. https:\/\/doi.org\/10.1016\/s1479-666x(09)80036-x.","DOI":"10.1016\/s1479-666x(09)80036-x"},{"key":"1557_CR16","doi-asserted-by":"publisher","unstructured":"Rajbhandari SM, Wilson RM. Unusual infections in diabetes. Diabetes Res Clin Pract. Feb. 1998;39(2):123\u20138. https:\/\/doi.org\/10.1016\/s0168-8227(97)00125-3.","DOI":"10.1016\/s0168-8227(97)00125-3"},{"key":"1557_CR17","doi-asserted-by":"publisher","unstructured":"Nisbet AA, Thompson IM. Impact of diabetes mellitus on the presentation and outcomes of Fournier\u2019s gangrene. Urology. Nov. 2002;60(5):775\u201379. https:\/\/doi.org\/10.1016\/s0090-4295(02)01951-9.","DOI":"10.1016\/s0090-4295(02)01951-9"},{"key":"1557_CR18","doi-asserted-by":"publisher","unstructured":"Sockkalingam VS, Subburayan E, Velu E, Rajashekar ST, Swamy AM. Fournier\u2019s gangrene: prospective study of 34 patients in South Indian population and treatment strategies. Pan Afr Med J. 2018;31. https:\/\/doi.org\/10.11604\/pamj.2018.31.110.15495.","DOI":"10.11604\/pamj.2018.31.110.15495"},{"key":"1557_CR19","unstructured":"Hubert J, Fournier G, Mangin P, Punga-Maole M. [Gangrene of the external genitalia]. Prog. en Urol. J. l\u2019Association Fr. d\u2019urologie la Soc. Fr. d\u2019urologie. Dec. 1995;5(6):911\u201324."},{"key":"1557_CR20","doi-asserted-by":"publisher","unstructured":"Smith GL, Bunker CB, Dinneen MD. Fournier\u2019s gangrene. Br. J. Urol. Mar. 1998;81(3):347\u201355. https:\/\/doi.org\/10.1046\/j.1464-410x.1998.00532.x.","DOI":"10.1046\/j.1464-410x.1998.00532.x"},{"key":"1557_CR21","doi-asserted-by":"crossref","unstructured":"Taviloglu K Cabioglu N, Cagatay A, Yanar H, Ertekin C, Baspinar I, Ozsut H, Guloglu R. Idiopathic necrotizing fasciitis: risk factors and strategies for management. Am. Surg. Apr. 2005;71(4):315\u201320.","DOI":"10.1177\/000313480507100408"},{"key":"1557_CR22","doi-asserted-by":"publisher","unstructured":"Ozkan OF, Alt\u00fdnl\u00fd E, Koksal N, Senger S, Celik A. Combining Flexi-Seal and negative pressure wound therapy for wound management in Fournier\u2019s gangrene. International wound journal. Jun. 2015;12(3):364\u201365. https:\/\/doi.org\/10.1111\/iwj.12103.","DOI":"10.1111\/iwj.12103"},{"key":"1557_CR23","unstructured":"Canbaz H, et al. [Fournier\u2019s gangrene: analysis of risk factors affecting the prognosis and cost of therapy in 18 cases]. Ulus travma ve acil Cerrahi Derg = Turkish J Trauma Emerg Surg TJTES. Jan. 2010;16(1):71\u20136."},{"key":"1557_CR24","doi-asserted-by":"publisher","first-page":"673121","DOI":"10.1155\/2013\/673121","volume":"2013","author":"S Aliyu","year":"2013","unstructured":"Aliyu S, G Ibrahim A, Ali N, M Waziri A. Fournier\u2019s gangrene as seen in University of Maiduguri Teaching Hospital. ISRN Urol. 2013;2013:673121. https:\/\/doi.org\/10.1155\/2013\/673121.","journal-title":"ISRN Urol"},{"issue":"1","key":"1557_CR25","doi-asserted-by":"publisher","first-page":"e0227748","DOI":"10.1371\/journal.pone.0227748","volume":"15","author":"C-T Hsiao","year":"2020","unstructured":"Hsiao C-T, Chang C-P, Huang T-Y, Chen Y-C, Fann W-C. Prospective validation of the Laboratory Risk Indicator for necrotizing Fasciitis (LRINEC) score for necrotizing Fasciitis of the extremities. PLoS ONE. 2020;15(1):e0227748. https:\/\/doi.org\/10.1371\/journal.pone.0227748.","journal-title":"PLoS ONE"},{"key":"1557_CR26","doi-asserted-by":"publisher","unstructured":"Liao C-I, Lee Y-K, Su Y-C, Chuang C-H, Wong C-H. Validation of the laboratory risk indicator for necrotizing fasciitis (LRINEC) score for early diagnosis of necrotizing fasciitis. Tzu Chi Med. J. Jun. 2012;24(2):73\u20136. https:\/\/doi.org\/10.1016\/j.tcmj.2012.02.009.","DOI":"10.1016\/j.tcmj.2012.02.009"},{"key":"1557_CR27","doi-asserted-by":"publisher","first-page":"2105","DOI":"10.2147\/IDR.S313321","volume":"14","author":"H Wu","year":"2021","unstructured":"Wu H, Liu S, Li C, Song Z. Modified Laboratory Risk Indicator for necrotizing Fasciitis (m-LRINEC) score system in diagnosing necrotizing fasciitis: a nested case-control study. Infect Drug Resist. 2021;14:2105\u201312. https:\/\/doi.org\/10.2147\/IDR.S313321.","journal-title":"Infect Drug Resist"},{"key":"1557_CR28","doi-asserted-by":"publisher","unstructured":"Kishino T et al. Jun., Usefulness of serum procalcitonin for necrotizing fasciitis as an early diagnostic tool., J. Infect. Chemother. Off. J. Japan Soc. Chemother. 2021;27(6):787\u201393. https:\/\/doi.org\/10.1016\/j.jiac.2021.01.002","DOI":"10.1016\/j.jiac.2021.01.002"},{"key":"1557_CR29","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1186\/s13017-018-0187-0","volume":"13","author":"C Wetterauer","year":"2018","unstructured":"Wetterauer C, et al. A contemporary case series of Fournier\u2019s gangrene at a Swiss tertiary care center-can scoring systems accurately predict mortality and morbidity? World J Emerg Surg. 2018;13:25. https:\/\/doi.org\/10.1186\/s13017-018-0187-0.","journal-title":"World J Emerg Surg"},{"key":"1557_CR30","doi-asserted-by":"publisher","unstructured":"Narasimhan V, Ooi G, Weidlich S, Carson P. Laboratory Risk Indicator for necrotizing Fasciitis score for early diagnosis of necrotizing fasciitis in Darwin. ANZ J Surg. Jan. 2018;88:1\u20132. https:\/\/doi.org\/10.1111\/ans.13895.","DOI":"10.1111\/ans.13895"},{"key":"1557_CR31","doi-asserted-by":"publisher","unstructured":"Bechar J, Sepehripour S, Hardwicke J, Filobbos G. Laboratory risk indicator for necrotising fasciitis (LRINEC) score for the assessment of early necrotising fasciitis: a systematic review of the literature. Ann R Coll Surg Engl. May 2017;99(5):341\u20136. https:\/\/doi.org\/10.1308\/rcsann.2017.0053.","DOI":"10.1308\/rcsann.2017.0053"},{"key":"1557_CR32","doi-asserted-by":"publisher","unstructured":"R K, Tandup C, Reddy D, Jayant D, Naik K, Sahu S, Thakur V, Khare S, Sakaray Y, Irrinki S, Kaman L. Prospective Validation and Comparison of Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) and Site Other Than Lower Limb, Immunosuppression, Age, Renal Impairment, and Inflammatory Markers (SIARI) Scoring Systems for Necrotizing Fasciitis. J. Surg. Res. Mar. 2023;283:719\u201325. https:\/\/doi.org\/10.1016\/j.jss.2022.11.001.","DOI":"10.1016\/j.jss.2022.11.001"},{"issue":"2","key":"1557_CR33","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1053\/j.jfas.2021.09.015","volume":"61","author":"A Tarricone","year":"2022","unstructured":"Tarricone A, et al. A systematic review and Meta-analysis of the effectiveness of LRINEC score for Predicting Upper and Lower Extremity necrotizing Fasciitis. J foot Ankle Surg off Publ Am Coll Foot Ankle Surg. 2022;61(2):384\u20139. https:\/\/doi.org\/10.1053\/j.jfas.2021.09.015.","journal-title":"J foot Ankle Surg off Publ Am Coll Foot Ankle Surg"}],"container-title":["BMC Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12894-024-01557-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12894-024-01557-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12894-024-01557-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T02:02:26Z","timestamp":1723600946000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcurol.biomedcentral.com\/articles\/10.1186\/s12894-024-01557-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,14]]},"references-count":33,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["1557"],"URL":"https:\/\/doi.org\/10.1186\/s12894-024-01557-x","relation":{},"ISSN":["1471-2490"],"issn-type":[{"value":"1471-2490","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,14]]},"assertion":[{"value":"4 December 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 July 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 August 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study protocol was reviewed and approved by the Institutional Review Board of Sakarya University College of Medicine (approval number: 145948-178). The need for informed consent was waived due to the retrospective design of the study. All experiments were performed in accordance with relevant guidelines and regulations.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"173"}}