{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T11:53:22Z","timestamp":1793793202782,"version":"4.6.1"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,5,10]],"date-time":"2025-05-10T00:00:00Z","timestamp":1746835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,5,10]],"date-time":"2025-05-10T00:00:00Z","timestamp":1746835200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"the Key Research and Development Program of Hebei Province","award":["19277714D"],"award-info":[{"award-number":["19277714D"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Urol"],"DOI":"10.1186\/s12894-025-01787-7","type":"journal-article","created":{"date-parts":[[2025,5,10]],"date-time":"2025-05-10T05:37:54Z","timestamp":1746855474000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Possible iodophor-induced systemic iodine toxicity during transurethral seminal vesiculoscopy: a case report and literature review"],"prefix":"10.1186","volume":"25","author":[{"given":"Meng","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huanhuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianli","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,5,10]]},"reference":[{"issue":"2","key":"1787_CR1","first-page":"1339","volume":"14","author":"S Hu","year":"2022","unstructured":"Hu S, Lu W, Di Y, et al. Comparison of the disinfection effect of iodophor at two different temperatures on the skin of surgical field and its influence on blood pressure and heart rate of patients. Am J Transl Res. 2022;14(2):1339\u201346.","journal-title":"Am J Transl Res"},{"issue":"1","key":"1787_CR2","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1007\/s00784-021-04048-7","volume":"26","author":"L Gou","year":"2022","unstructured":"Gou L, Zhao R, Ren X, et al. Oral transmucosal absorption of iodine after intraoral Preparation with povidone-iodine prior to oral surgeries: a randomized controlled study in 12 male patients. Clin Oral Investig. 2022;26(1):705\u201311.","journal-title":"Clin Oral Investig"},{"issue":"4","key":"1787_CR3","first-page":"e24034","volume":"14","author":"P Papadopoulos","year":"2022","unstructured":"Papadopoulos P, Iordanou S, Georgiou F, et al. Povidone-Iodine-Induced acute kidney injury in a 23-Year-Old woman: the first clinical case report from the Republic of Cyprus. Cureus. 2022;14(4):e24034.","journal-title":"Cureus"},{"key":"1787_CR4","first-page":"5528210","volume":"2021","author":"Y Vercammen","year":"2021","unstructured":"Vercammen Y, Dauwe D, De Vlieger G, et al. Povidone iodine disinfection associated with hypothyroidism and potentially contributing to prolonged kidney failure. Case Rep Crit Care. 2021;2021:5528210.","journal-title":"Case Rep Crit Care"},{"key":"1787_CR5","doi-asserted-by":"crossref","unstructured":"Zellama D, Ayed S, Azzabi A, et al. Acute kidney injury due to Povidone-Iodine. Saudi J Kidney Dis Transpl. 2020 Sep-Oct;31(5):1125\u20138.","DOI":"10.4103\/1319-2442.301181"},{"issue":"34","key":"1787_CR6","doi-asserted-by":"publisher","first-page":"e34631","DOI":"10.1097\/MD.0000000000034631","volume":"102","author":"R Suzuki","year":"2023","unstructured":"Suzuki R, Suzuki S. Povidone-iodine-induced transient Triiodothyronine thyrotoxicosis in a Japanese patient with prolonged habitual gargling: A case report and literature review. Med (Baltim). 2023;102(34):e34631.","journal-title":"Med (Baltim)"},{"issue":"7","key":"1787_CR7","doi-asserted-by":"publisher","first-page":"e7693","DOI":"10.1002\/ccr3.7693","volume":"11","author":"CJ Rasner","year":"2023","unstructured":"Rasner CJ, Allen T, Kavalier M. Topical betadine exposure precipitating sterile cerebritis and systemic iodine toxicity. Clin Case Rep. 2023;11(7):e7693.","journal-title":"Clin Case Rep"},{"issue":"1","key":"1787_CR8","first-page":"26","volume":"32","author":"LG Liao","year":"2017","unstructured":"Liao LG, Li YF, Zhu T, et al. Clinical analysis of 216 cases of refractory hematospermia diagnosed and treated by seminal duct endoscopy. J Clin Urol. 2017;32(1):26\u201338. [Google Scholar].","journal-title":"J Clin Urol"},{"key":"1787_CR9","doi-asserted-by":"crossref","unstructured":"Zheng T, Zhang TB, Lv KL, et al. A comparative study on the success rates of two approaches for seminal vesiculoscopy. Am J Mens Health. 2022 Jul-Aug;16(4):15579883221115615.","DOI":"10.1177\/15579883221115615"},{"issue":"1","key":"1787_CR10","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1186\/s12894-021-00817-4","volume":"21","author":"WK Chen","year":"2021","unstructured":"Chen WK, Yu DD, Chen ZX, et al. Transurethral seminal vesiculoscopy for intractable hematospermia: experience from 144 patients. BMC Urol. 2021;21(1):48.","journal-title":"BMC Urol"},{"issue":"3","key":"1787_CR11","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1053\/ajkd.2003.50134","volume":"41","author":"S Kanakiriya","year":"2003","unstructured":"Kanakiriya S, De Chazal I, Nath KA, et al. Iodine toxicity treated with Hemodialysis and continuous venovenous hemodiafiltration. Am J Kidney Dis. 2003;41(3):702\u20138.","journal-title":"Am J Kidney Dis"},{"issue":"1","key":"1787_CR12","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/S0750-7658(02)00850-X","volume":"22","author":"G Labb\u00e9","year":"2003","unstructured":"Labb\u00e9 G, Mahul P, Morel J, et al. Intoxication \u00e0 L\u2019iode Apr\u00e8s irrigations sous-cutan\u00e9es de Povidone Iod\u00e9e [Iodine intoxication after subcutaneous irrigations of Povidone iodine]. Ann Fr Anesth Reanim. 2003;22(1):58\u201360. French.","journal-title":"Ann Fr Anesth Reanim"},{"issue":"5","key":"1787_CR13","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1016\/S0003-4975(10)61965-0","volume":"39","author":"PL Glick","year":"1985","unstructured":"Glick PL, Guglielmo BJ, Tranbaugh RF, et al. Iodine toxicity in a patient treated by continuous povidone-iodine mediastinal irrigation. Ann Thorac Surg. 1985;39(5):478\u201380.","journal-title":"Ann Thorac Surg"},{"issue":"1","key":"1787_CR14","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1177\/0310057X1103900121","volume":"39","author":"H Ramaswamykanive","year":"2011","unstructured":"Ramaswamykanive H, Nanavati Z, Mackie J, et al. Cardiovascular collapse following povidone-iodine wash. Anaesth Intensive Care. 2011;39(1):127\u201330.","journal-title":"Anaesth Intensive Care"},{"issue":"6","key":"1787_CR15","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1016\/S1053-0770(99)90130-1","volume":"13","author":"M Ryan","year":"1999","unstructured":"Ryan M, Al-Sammak Z, Phelan D. Povidone-iodine mediastinal irrigation: a cause of acute renal failure. J Cardiothorac Vasc Anesth. 1999;13(6):729\u201331.","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"1787_CR16","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/S0140-6736(76)91406-9","volume":"I","author":"J Pietsch","year":"1976","unstructured":"Pietsch J, Meakins JL. Complications of povidone-iodine absorption in topically treated burn patient. Lancet. 1976;I:280\u20132.","journal-title":"Lancet"},{"issue":"6","key":"1787_CR17","first-page":"704","volume":"120","author":"RF Dyck","year":"1979","unstructured":"Dyck RF, Bear RA, Goldstein MB, Halperin ML. Iodine\/iodide toxic reaction: case report with emphasis on the nature of the metabolic acidosis. Can Med Assoc J. 1979;120(6):704\u20136.","journal-title":"Can Med Assoc J"},{"issue":"6","key":"1787_CR18","doi-asserted-by":"publisher","first-page":"1527","DOI":"10.1002\/emp2.12192","volume":"1","author":"HY Liang","year":"2020","unstructured":"Liang HY, Cheng SC, Chang CH, et al. Hypoxia, hypotension, and bradycardia induced by povidone-iodine ingestion: A pediatric case report and literature review. J Am Coll Emerg Physicians Open. 2020;1(6):1527\u20139.","journal-title":"J Am Coll Emerg Physicians Open"},{"issue":"1","key":"1787_CR19","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1186\/s12893-023-02290-2","volume":"23","author":"RJ Yao","year":"2023","unstructured":"Yao RJ, Xiao H, Chen SS, et al. Efficacy of various surgical approaches in treating hematospermia using transurethral seminal vesiculoscopy. BMC Surg. 2023;23(1):385.","journal-title":"BMC Surg"},{"issue":"5","key":"1787_CR20","first-page":"e38648","volume":"15","author":"Y Chirumamilla","year":"2023","unstructured":"Chirumamilla Y, Palanisamy N, Ogbon EOO, et al. Unveiling of type B lactic acidosis from systemic lupus Erythematosus-Associated B-cell lymphoma: A fatal oncology emergency. Cureus. 2023;15(5):e38648.","journal-title":"Cureus"},{"key":"1787_CR21","doi-asserted-by":"publisher","first-page":"1496","DOI":"10.3390\/ph15121496","volume":"15","author":"C Zanza","year":"2022","unstructured":"Zanza C, Facelli V, Romenskaya T, et al. Lactic acidosis related to pharmacotherapy and human diseases. Pharmaceuticals (Basel). 2022;15:1496.","journal-title":"Pharmaceuticals (Basel)"},{"issue":"48","key":"1787_CR22","doi-asserted-by":"publisher","first-page":"e8879","DOI":"10.1097\/MD.0000000000008879","volume":"96","author":"CS Kim","year":"2017","unstructured":"Kim CS, Kim SS, Bae EH, Ma SK, Kim SW. Acute kidney injury due to povidone-iodine ingestion: A case report. Med (Baltim). 2017;96(48):e8879.","journal-title":"Med (Baltim)"}],"container-title":["BMC Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12894-025-01787-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12894-025-01787-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12894-025-01787-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,10]],"date-time":"2025-05-10T05:37:56Z","timestamp":1746855476000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcurol.biomedcentral.com\/articles\/10.1186\/s12894-025-01787-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,10]]},"references-count":22,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["1787"],"URL":"https:\/\/doi.org\/10.1186\/s12894-025-01787-7","relation":{},"ISSN":["1471-2490"],"issn-type":[{"value":"1471-2490","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,10]]},"assertion":[{"value":"1 August 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 April 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 May 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study has been approved by the ethics committee of the Hebei General Hospital (ethics approval no.2024022).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval and consent to participate"}},{"value":"the patient provided written informed consent for publication of this case report.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"118"}}