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Informed consent to participate was not applicable because this study did not involve human participants, human tissue, or identifiable human data. This study did not involve human participants, human tissue, or identifiable human data; therefore, ethical approval and informed consent were not required. All experiments were conducted using commercially available human fibroblast cell lines (HFF-1, ATCC\n                      \u00ae\n                      SCRC-1041\u2122), animal-derived acellular tilapia skin obtained from a licensed seafood supplier, and standard laboratory bacterial strains (\n                      Staphylococcus aureus\n                      ATCC 25923 and\n                      Escherichia coli\n                      ATCC 25922). All procedures involving cell culture, bacterial handling, scaffold sterilization, and in vitro biological testing were performed in accordance with the institutional biosafety guidelines and standard laboratory biosafety practices of Urmia University of Medical Sciences.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"72"}}