{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T01:08:29Z","timestamp":1791594509023,"version":"4.3.4"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Key research and development program of Zhejiang province","award":["2019C03010"],"award-info":[{"award-number":["2019C03010"]}]},{"name":"Zhejiang Provincial Natural Science Foundation of China","award":["LY21H160032"],"award-info":[{"award-number":["LY21H160032"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Endocr Disord"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Ovarian steroid cell tumors (SCTs), not otherwise specified (NOS), are rare, with few large studies. The purpose of this study was to analyze the clinical features, prognosis, and treatment choices for these patients of different age groups.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This was a retrospective study. We identified nine cases of ovarian steroid cell tumor, not otherwise specified, confirmed by post-operative histopathological examination, and analyzed clinical features, surgical procedures, and follow up outcomes. We also reviewed cases reports of ovarian steroid cell tumors, not otherwise specified.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A total of nine cases were included. The age range was 9\u201368 years (mean, 41.89\u2009\u00b1\u200919.72 years). Clinical features included virilization, amenorrhea, abdominal pain, vaginal bleeding, isosexual precocious puberty, Cushing\u2019s syndrome, and abnormal weight gain with elevated testosterone levels. The follow up interval ranged 5\u201353 months and no recurrence was observed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Ovarian steroid cell tumors covered all age groups, with manifestations of androgen excess. Younger patients appeared to have a more favorable prognosis, which provided more opportunities for these patients to pursue treatment options that will preserve reproductive function.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12902-022-01170-9","type":"journal-article","created":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T02:02:34Z","timestamp":1667268154000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Ovarian steroid cell tumors, not otherwise specified: analysis of nine cases with a literature review"],"prefix":"10.1186","volume":"22","author":[{"given":"Mengyan","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kechun","family":"Bao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingjia","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuhang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodong","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fenfen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,11,1]]},"reference":[{"key":"1170_CR1","doi-asserted-by":"crossref","unstructured":"Boussios S, Moschetta M, Zarkavelis G, Papadaki A, Kefas A, Tatsi K: Ovarian sex-cord stromal tumours and small cell tumours: Pathological, genetic and management aspects. Critical reviews in oncology\/hematology 2017, 120:43\u201351.","DOI":"10.1016\/j.critrevonc.2017.10.007"},{"key":"1170_CR2","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1097\/00000478-198711000-00002","volume":"11","author":"MC Hayes","year":"1987","unstructured":"Hayes MC, Scully RE. Ovarian steroid cell tumors (not otherwise specified):a clinicopathological analysis of 63 cases. Am J Surg Pathol. 1987;11:835\u201345.","journal-title":"Am J Surg Pathol"},{"key":"1170_CR3","first-page":"4375839","volume":"2019","author":"EC Tan","year":"2019","unstructured":"Tan EC, Khong CC, Bhutia K. A rare case of steroid cell tumor, not otherwise specified (NOS), of the Ovary in a Young Woman. Case Rep Obstet Gynecol. 2019;2019:4375839.","journal-title":"Case Rep Obstet Gynecol"},{"key":"1170_CR4","doi-asserted-by":"crossref","unstructured":"Alves P, Sa I, Brito M, Carnide C, Moutinho O. An early diagnosis of an ovarian steroid cell tumor not otherwise specified in a woman. Case reports in obstetrics and gynecology 2019, 2019:2537480\u20132537480.","DOI":"10.1155\/2019\/2537480"},{"issue":"4","key":"1170_CR5","first-page":"443","volume":"55","author":"S Y\u0131lmaz-A\u011fladio\u011flu","year":"2013","unstructured":"Y\u0131lmaz-A\u011fladio\u011flu S, Sava\u015f-Erdeve \u015e, Boduro\u011flu E, \u00d6nder A, Karaman \u0130, \u00c7etinkaya S, Aycan Z. A girl with steroid cell ovarian tumor misdiagnosed as non-classical congenital adrenal hyperplasia. Turk J Pediatr. 2013;55(4):443\u20136.","journal-title":"Turk J Pediatr"},{"issue":"8","key":"1170_CR6","doi-asserted-by":"publisher","first-page":"867","DOI":"10.3109\/01443615.2015.1022141","volume":"35","author":"T Yokozawa","year":"2015","unstructured":"Yokozawa T, Asano R, Nakamura T, Furuya M, Nagashima Y, Koyama-Sato M, Kanda Y, Hirahara F, Sakakibara H. Steroid cell tumour, not otherwise specified: Rare case with primary amenorrhoea in a 16-year-old. J Obstet gynaecology: J Inst Obstet Gynecol. 2015;35(8):867\u20138.","journal-title":"J Obstet gynaecology: J Inst Obstet Gynecol"},{"issue":"6","key":"1170_CR7","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1515\/JPEM.2000.13.6.663","volume":"13","author":"F Bas","year":"2000","unstructured":"Bas F, Saka N, Darendeliler F, Tuzlali S, Ilhan R, Bundak R, Gunoz H. Bilateral ovarian steroid cell tumor in congenital adrenal hyperplasia due to classic 11 beta-hydroxylase deficiency. J Pediatr Endocrinol metabolism: JPEM. 2000;13(6):663\u20137.","journal-title":"J Pediatr Endocrinol metabolism: JPEM"},{"issue":"2","key":"1170_CR8","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1016\/j.tjog.2013.04.037","volume":"53","author":"YJ Tai","year":"2014","unstructured":"Tai YJ, Chang WC, Kuo KT, Sheu BC. Ovarian steroid cell tumor, not otherwise specified, with virilization symptoms. Taiwan J Obstet Gynecol. 2014;53(2):260\u20132.","journal-title":"Taiwan J Obstet Gynecol"},{"key":"1170_CR9","doi-asserted-by":"crossref","unstructured":"Faten H, Dorra G, Slim C, Wajdi S, Nadia C, Kais C, Tahia B, Mohamed A: Ovarian steroid cell tumor (not otherwise specified): a case report of ovarian hyperandrogenism. Case reports in oncological medicine 2020, 2020:6970823.","DOI":"10.1155\/2020\/6970823"},{"issue":"3","key":"1170_CR10","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1016\/j.jmig.2020.08.018","volume":"28","author":"A Bercow","year":"2021","unstructured":"Bercow A, Nitecki R, Brady PC, Rauh-Hain JA. Outcomes after Fertility-sparing Surgery for Women with Ovarian Cancer: A Systematic Review of the Literature. J Minim Invasive Gynecol. 2021;28(3):527\u201336.e521.","journal-title":"J Minim Invasive Gynecol"},{"key":"1170_CR11","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1016\/S0020-7292(09)62498-X","volume":"107","author":"F Akimasa","year":"2009","unstructured":"Akimasa F, Yasuyuki H, Masanobu O, Norio K, Koutarou U, Kazuo S. P1012 An ovarian steroid cell tumor, not otherwise specified with pregnancy causing fetal 46,XX disorder of sex development. Int J Gynecol Obstet. 2009;107:697\u20137.","journal-title":"Int J Gynecol Obstet"},{"issue":"1","key":"1170_CR12","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1007\/s00404-014-3165-0","volume":"290","author":"M Oz","year":"2014","unstructured":"Oz M, Ozg\u00fc E, T\u00fcrker M, Erkaya S, G\u00fcng\u00f6r T. Steroid cell tumor of the ovary in a pregnant woman whose androgenic symptoms were masked by pregnancy. Arch Gynecol Obstet. 2014;290(1):131\u20134.","journal-title":"Arch Gynecol Obstet"},{"key":"1170_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jare.2018.02.006","volume":"12","author":"S Boussios","year":"2018","unstructured":"Boussios S, Moschetta M, Tatsi K, Tsiouris AK, Pavlidis N. A review on pregnancy complicated by ovarian epithelial and non-epithelial malignant tumors: Diagnostic and therapeutic perspectives. J Adv Res. 2018;12:1\u20139.","journal-title":"J Adv Res"},{"issue":"3","key":"1170_CR14","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1111\/jog.12537","volume":"41","author":"S Haroon","year":"2015","unstructured":"Haroon S, Idrees R, Fatima S, Memon A, Kayani N. Ovarian steroid cell tumor, not otherwise specified: a clinicopathological and immunohistochemical experience of 12 cases. J Obstet Gynaecol Res. 2015;41(3):424\u201331.","journal-title":"J Obstet Gynaecol Res"},{"issue":"1","key":"1170_CR15","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1159\/000506044","volume":"13","author":"T Yoshimatsu","year":"2020","unstructured":"Yoshimatsu T, Nagai K, Miyawaki R, Moritani K, Ohkubo K, Kuwabara J, Tatsuta K, Kurata M, Fukushima M, Kitazawa R, et al. Malignant ovarian steroid cell tumor, not otherwise specified, causes virilization in a 4-year-old girl: a case report and literature review. Case Rep Oncol. 2020;13(1):358\u201364.","journal-title":"Case Rep Oncol"},{"issue":"6","key":"1170_CR16","doi-asserted-by":"publisher","first-page":"839","DOI":"10.3892\/mco.2016.1071","volume":"5","author":"L Qian","year":"2016","unstructured":"Qian L, Shen Z, Zhang X, Wu D, Zhou Y. Ovarian steroid cell tumor, not otherwise specified: a case report and literature review. Mol Clin Oncol. 2016;5(6):839\u201341.","journal-title":"Mol Clin Oncol"},{"issue":"7","key":"1170_CR17","doi-asserted-by":"publisher","first-page":"875","DOI":"10.4158\/EP.14.7.875","volume":"14","author":"P Gupta","year":"2008","unstructured":"Gupta P, Goyal S, Gonzalez-Mendoza LE, Noviski N, Vezmar M, Brathwaite CD, Misra M. Corticotropin-independent cushing syndrome in a child with an ovarian tumor misdiagnosed as nonclassic congenital adrenal hyperplasia. Endocr practice: official J Am Coll Endocrinol Am Association Clin Endocrinologists. 2008;14(7):875\u20139.","journal-title":"Endocr practice: official J Am Coll Endocrinol Am Association Clin Endocrinologists"},{"issue":"2","key":"1170_CR18","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1007\/s12020-009-9150-x","volume":"35","author":"P Sawathiparnich","year":"2009","unstructured":"Sawathiparnich P, Sitthinamsuwan P, Sanpakit K, Laohapensang M, Chuangsuwanich T. Cushing\u2019s syndrome caused by an ACTH-producing ovarian steroid cell tumor, NOS, in a prepubertal girl. Endocrine. 2009;35(2):132\u20135.","journal-title":"Endocrine"},{"issue":"6","key":"1170_CR19","doi-asserted-by":"publisher","first-page":"836","DOI":"10.3346\/jkms.2011.26.6.836","volume":"26","author":"SH Lee","year":"2011","unstructured":"Lee SH, Kang MS, Lee GS, Chung WY. Refractory hypertension and isosexual pseudoprecocious puberty associated with renin-secreting ovarian steroid cell tumor in a girl. J Korean Med Sci. 2011;26(6):836\u20138.","journal-title":"J Korean Med Sci"},{"issue":"1","key":"1170_CR20","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/j.jpag.2020.08.001","volume":"34","author":"EM Schnuckle","year":"2020","unstructured":"Schnuckle EM, Williamson A, Carpentieri D, Taylor S. Ovarian sex cord stromal tumor, steroid cell, NOS in an adolescent: a case report. J Pediatr Adolesc Gynecol. 2020;34(1):94\u20137.","journal-title":"J Pediatr Adolesc Gynecol"},{"issue":"4","key":"1170_CR21","first-page":"1434","volume":"12","author":"X Yuan","year":"2019","unstructured":"Yuan X, Sun Y, Jin Y, Chen X, Wang X, Ji T, Wang C, Dai H. Ovarian steroid cell tumor, not otherwise specified, treated with surgery: a case report and review of literature. Int J Clin Exp Pathol. 2019;12(4):1434\u20138.","journal-title":"Int J Clin Exp Pathol"},{"issue":"9","key":"1170_CR22","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.1007\/s10815-013-0051-9","volume":"30","author":"L Sielert","year":"2013","unstructured":"Sielert L, Liu C, Nagarathinam R, Craig L. Androgen-producing steroid cell ovarian tumor in a young woman and subsequent spontaneous pregnancy. J Assist Reprod Genet. 2013;30(9):1157\u201360.","journal-title":"J Assist Reprod Genet"},{"key":"1170_CR23","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1186\/1757-2215-6-53","volume":"6","author":"W Jiang","year":"2013","unstructured":"Jiang W, Tao X, Fang F, Zhang S, Xu C. Benign and malignant ovarian steroid cell tumors, not otherwise specified: case studies, comparison, and review of the literature. J ovarian Res. 2013;6:53.","journal-title":"J ovarian Res"},{"issue":"4","key":"1170_CR24","first-page":"336","volume":"10","author":"RE Santo","year":"2016","unstructured":"Santo RE, Sabino T, Agapito A. Ovarian steroid cell tumor not otherwise specified with virilizing manifestations: case report. Acta Obst\u00e9trica e Ginecol\u00f3gica Portuguesa. 2016;10(4):336\u20139.","journal-title":"Acta Obst\u00e9trica e Ginecol\u00f3gica Portuguesa"},{"issue":"5","key":"1170_CR25","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1097\/PGP.0b013e31821643a3","volume":"30","author":"X Zhang","year":"2011","unstructured":"Zhang X, Lue B. Ovarian steroid cell tumor, not otherwise specified (NOS): an unusual case with myelolipoma. Int J Gynecol pathology: official J Int Soc Gynecol Pathologists. 2011;30(5):460\u20135.","journal-title":"Int J Gynecol pathology: official J Int Soc Gynecol Pathologists"},{"issue":"3","key":"1170_CR26","doi-asserted-by":"publisher","first-page":"133","DOI":"10.5387\/fms.2019-25","volume":"65","author":"J Matsukawa","year":"2019","unstructured":"Matsukawa J, Takahashi T, Hada Y, Kameda W, Ota K, Fukase M, Takahashi K, Matsuo K, Mizunuma H, Nagase S. Successful laparoscopic resection of virilizing ovarian steroid cell tumor, not otherwise specified, in a 22-year-old woman: a case report and evaluation of the steroidogenic pathway. Fukushima J Med Sci. 2019;65(3):133\u20139.","journal-title":"Fukushima J Med Sci"},{"issue":"suppl_1","key":"1170_CR27","doi-asserted-by":"publisher","first-page":"A203","DOI":"10.1093\/ajcp\/138.suppl1.187","volume":"138","author":"RMD Arora","year":"2012","unstructured":"Arora RMD, Eble JNMD, Pierce HHP, Crispen PLMD, Desimone CPMD, Lee EYMD, Karabakhtsian RGMD. Bilateral ovarian steroid cell tumors and massive macronodular adrenocortical disease in a patient with hereditary leiomyomatosis and renal cell cancer syndrome. Am J Clin Pathol. 2012;138(suppl_1):A203.","journal-title":"Am J Clin Pathol"},{"key":"1170_CR28","doi-asserted-by":"crossref","unstructured":"Wong FCK, Chan AZ, Wong WS, Kwan AHW, Law TSM, Chung JPW, Kwok JSS, Chan AOK: Hyperandrogenism, elevated 17-hydroxyprogesterone and its urinary metabolites in a young woman with ovarian steroid cell tumor, not otherwise specified: case report and review of the literature. Case Rep Endocrinol 2019, 2019:9237459.","DOI":"10.1155\/2019\/9237459"},{"issue":"1","key":"1170_CR29","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/1472-6823-14-59","volume":"14","author":"Y Menghua","year":"2014","unstructured":"Menghua Y, Mingcai Q, Mei Z. Symptomatic Cushing syndrome and hyperandrogenemia revealing steroid cell ovarian neoplasm with late intra-abdominal metastasis. BMC Endocr disorders. 2014;14(1):59\u201372.","journal-title":"BMC Endocr disorders"},{"key":"1170_CR30","first-page":"130030","volume":"2013","author":"J Swain","year":"2013","unstructured":"Swain J, Sharma S, Prakash V, Agrawal NK, Singh SK. Steroid cell tumor: a rare cause of hirsutism in a female. Endocrinol diabetes metabolism case Rep. 2013;2013:130030.","journal-title":"Endocrinol diabetes metabolism case Rep"},{"issue":"2","key":"1170_CR31","doi-asserted-by":"publisher","first-page":"770","DOI":"10.3892\/ol.2014.2233","volume":"8","author":"K Li","year":"2014","unstructured":"Li K, Zhu F, Xiong J, Liu F. A rare occurrence of a malignant ovarian steroid cell tumor not otherwise specified: a case report and literature review. Oncol Lett. 2014;8(2):770\u20134.","journal-title":"Oncol Lett"},{"issue":"1","key":"1170_CR32","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1016\/j.ygyno.2004.12.037","volume":"97","author":"A-x Liu","year":"2005","unstructured":"Liu A-x, Sun J, Shao W-q. Jin H-m, Song W-q: Steroid cell tumors, not otherwise specified (NOS), in an accessory ovary: a case report and literature review. Gynecol Oncol. 2005;97(1):260\u20132.","journal-title":"Gynecol Oncol"},{"issue":"1","key":"1170_CR33","doi-asserted-by":"publisher","first-page":"39","DOI":"10.6118\/jmm.2014.20.1.39","volume":"20","author":"D-H Chung","year":"2014","unstructured":"Chung D-H, Lee S-H, Lee K-B. A case of ovarian steroid cell tumor, not otherwise specified, treated with surgery and gonadotropin releasing hormone agonist. J Menopausal Med. 2014;20(1):39\u201342.","journal-title":"J Menopausal Med"},{"issue":"3","key":"1170_CR34","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1080\/09513590801917106","volume":"24","author":"JW Stephens","year":"2008","unstructured":"Stephens JW, Fielding A, Verdaguer R, Freites O. A steroid-cell tumor of the ovary resulting in massive androgen excess early in the gonadol steroidogenic pathway. Gynecol endocrinology: official J Int Soc Gynecol Endocrinol. 2008;24(3):151\u20133.","journal-title":"Gynecol endocrinology: official J Int Soc Gynecol Endocrinol"},{"issue":"1","key":"1170_CR35","first-page":"10","volume":"3","author":"MA Ben Haj Hassine","year":"2015","unstructured":"Ben Haj Hassine MA, Msakni I, Siala H, Rachdi R. Laparoscopic management of an ovarian steroid cell tumor, not otherwise specified causing virilization and amenorrhea: a case report. Case Rep Clin Pathol. 2015;3(1):10\u20133.","journal-title":"Case Rep Clin Pathol"},{"issue":"3","key":"1170_CR36","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1210\/jc.2017-01977","volume":"103","author":"S Chen","year":"2018","unstructured":"Chen S, Li R, Zhang X, Lu L, Li J, Pan H, Zhu H. Combined ovarian and adrenal venous sampling in the localization of adrenocorticotropic hormone-independent ectopic Cushing syndrome. J Clin Endocrinol Metab. 2018;103(3):803\u20138.","journal-title":"J Clin Endocrinol Metab"},{"issue":"6","key":"1170_CR37","doi-asserted-by":"publisher","first-page":"412","DOI":"10.3109\/09513590.2010.495432","volume":"27","author":"M Varras","year":"2011","unstructured":"Varras M, Vasilakaki T, Skafida E, Akrivis C. Clinical, ultrasonographic, computed tomography and histopathological manifestations of ovarian steroid cell tumour, not otherwise specified: our experience of a rare case with female virilisation and review of the literature. Gynecol endocrinology: official J Int Soc Gynecol Endocrinol. 2011;27(6):412\u20138.","journal-title":"Gynecol endocrinology: official J Int Soc Gynecol Endocrinol"},{"issue":"37","key":"1170_CR38","doi-asserted-by":"publisher","first-page":"e7998","DOI":"10.1097\/MD.0000000000007998","volume":"96","author":"L Zang","year":"2017","unstructured":"Zang L, Ye M, Yang G, Li J, Liu M, Du J, Gu W, Jin N, Yang L, Ba J, et al. Accessory ovarian steroid cell tumor producing testosterone and cortisol: a case report. Medicine. 2017;96(37):e7998.","journal-title":"Medicine"},{"issue":"6","key":"1170_CR39","doi-asserted-by":"publisher","first-page":"534","DOI":"10.5468\/ogs.2014.57.6.534","volume":"57","author":"JS Kim","year":"2014","unstructured":"Kim JS, Park SN, Kim BR. Recurrent ovarian steroid cell tumor, not otherwise specified managed with debulking surgery, radiofrequency ablation, and adjuvant chemotherapy. Obstet Gynecol Sci. 2014;57(6):534\u20138.","journal-title":"Obstet Gynecol Sci"},{"issue":"2","key":"1170_CR40","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1006\/gyno.1999.5549","volume":"75","author":"MB Reedy","year":"1999","unstructured":"Reedy MB, Richards WE, Ueland F, Uy K, Lee EY, Bryant C, van Nagell JR Jr. Ovarian steroid cell tumors, not otherwise specified: a case report and literature review. Gynecol Oncol. 1999;75(2):293\u20137.","journal-title":"Gynecol Oncol"},{"key":"1170_CR41","doi-asserted-by":"crossref","unstructured":"Lee J, John VS, Liang SX, D\u2019Agostino CA, Menzin AW: Metastatic malignant ovarian steroid cell tumor: a case report and review of the literature. Case reports in obstetrics and gynecology 2016, 2016:6184573.","DOI":"10.1155\/2016\/6184573"},{"issue":"3","key":"1170_CR42","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/S0720-048X(96)01133-3","volume":"26","author":"PH Wang","year":"1998","unstructured":"Wang PH, Chao HT, Lee RC, Lai CR, Lee WL, Kwok CF, Yuan CC, Ng HT. Steroid cell tumors of the ovary: clinical, ultrasonic, and MRI diagnosis - a case report. Eur J Radiol. 1998;26(3):269\u201373.","journal-title":"Eur J Radiol"},{"key":"1170_CR43","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.gore.2019.07.006","volume":"29","author":"T Nakasone","year":"2019","unstructured":"Nakasone T, Nakamoto T, Matsuzaki A, Nakagami H, Aoki Y. Direct evidence on the efficacy of GnRH agonist in recurrent steroid cell tumor-not otherwise specified. Gynecologic Oncol Rep. 2019;29:73\u20135.","journal-title":"Gynecologic Oncol Rep"},{"issue":"1","key":"1170_CR44","doi-asserted-by":"publisher","first-page":"50","DOI":"10.5468\/OGS.2013.56.1.50","volume":"56","author":"YJ Chun","year":"2013","unstructured":"Chun YJ, Choi HJ, Lee HN, Cho S, Choi JH. An asymptomatic ovarian steroid cell tumor with complete cystic morphology: a case report. Obstet Gynecol Sci. 2013;56(1):50\u20135.","journal-title":"Obstet Gynecol Sci"},{"issue":"1","key":"1170_CR45","doi-asserted-by":"publisher","first-page":"142","DOI":"10.3349\/ymj.2007.48.1.142","volume":"48","author":"YT Kim","year":"2007","unstructured":"Kim YT, Kim SW, Yoon BS, Kim SH, Kim JH, Kim JW, Cho NH. An ovarian steroid cell tumor causing virilization and massive ascites. Yonsei Med J. 2007;48(1):142\u20136.","journal-title":"Yonsei Med J"},{"issue":"Suppl 1","key":"1170_CR46","doi-asserted-by":"publisher","first-page":"262","DOI":"10.4103\/2230-8210.119596","volume":"17","author":"SMA Cooray","year":"2013","unstructured":"Cooray SMA, Bulugahapitiya UDS, Samarasinghe K, Samarathunga P. Steroid cell tumor not otherwise specified of bilateral ovaries: a rare cause of post menopausal virilization. Indian J Endocrinol Metabol. 2013;17(Suppl 1):262\u20134.","journal-title":"Indian J Endocrinol Metabol"},{"issue":"5","key":"1170_CR47","doi-asserted-by":"publisher","first-page":"347","DOI":"10.3109\/09513599809012837","volume":"12","author":"G Faraj","year":"1998","unstructured":"Faraj G, Di Gregorio S, Misiunas A, Faure EN, Villabrile P, Stringa I, Petroff N, Bur G. Virilizing ovarian tumor of cell tumor type not otherwise specified: a case report. Gynecol endocrinology: official J Int Soc Gynecol Endocrinol. 1998;12(5):347\u201352.","journal-title":"Gynecol endocrinology: official J Int Soc Gynecol Endocrinol"},{"issue":"3","key":"1170_CR48","doi-asserted-by":"publisher","first-page":"107","DOI":"10.4197\/Med.18-3.8","volume":"18","author":"LS Abdullah","year":"2011","unstructured":"Abdullah LS. Ovarian steroid cell tumor, NOS presenting with massive ascites and elevated CA-125. JKAU Med Sci. 2011;18(3):107\u201314.","journal-title":"JKAU Med Sci"},{"issue":"4 Pt 2","key":"1170_CR49","first-page":"661","volume":"92","author":"CA Brewer","year":"1998","unstructured":"Brewer CA, Shevlin D. Encouraging response of an advanced steroid-cell tumor to GnRH agonist therapy. Obstet Gynecol. 1998;92(4 Pt 2):661\u20133.","journal-title":"Obstet Gynecol"},{"issue":"1","key":"1170_CR50","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1186\/s13256-016-1061-x","volume":"10","author":"R Sedhom","year":"2016","unstructured":"Sedhom R, Hu S, Ohri A, Infantino D, Lubitz S. Symptomatic Cushing\u2019s syndrome and hyperandrogenemia in a steroid cell ovarian neoplasm: a case report. J Med Case Rep. 2016;10(1):278.","journal-title":"J Med Case Rep"},{"issue":"6","key":"1170_CR51","doi-asserted-by":"publisher","first-page":"1468","DOI":"10.1093\/humrep\/17.6.1468","volume":"17","author":"JW Stephens","year":"2002","unstructured":"Stephens JW, Katz JR, McDermott N, MacLean AB, Bouloux PM. An unusual steroid-producing ovarian tumour: case report. Hum Reprod (Oxford England). 2002;17(6):1468\u201371.","journal-title":"Hum Reprod (Oxford England)"},{"key":"1170_CR52","doi-asserted-by":"crossref","unstructured":"Singh P, Deleon F, Anderson R. Steroid cell ovarian neoplasm, not otherwise specified: a case report and review of the literature. Case reports in obstetrics and gynecology 2012, 2012:253152.","DOI":"10.1155\/2012\/253152"},{"issue":"12","key":"1170_CR53","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1097\/00007611-200093120-00012","volume":"93","author":"JL Powell","year":"2000","unstructured":"Powell JL, Dulaney DP, Shiro BC. Androgen-secreting steroid cell tumor of the ovary. South Med J. 2000;93(12):1201\u20134.","journal-title":"South Med J"}],"container-title":["BMC Endocrine Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12902-022-01170-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12902-022-01170-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12902-022-01170-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T03:04:29Z","timestamp":1667271869000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcendocrdisord.biomedcentral.com\/articles\/10.1186\/s12902-022-01170-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,1]]},"references-count":53,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["1170"],"URL":"https:\/\/doi.org\/10.1186\/s12902-022-01170-9","relation":{},"ISSN":["1472-6823"],"issn-type":[{"value":"1472-6823","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,1]]},"assertion":[{"value":"10 April 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 September 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 November 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was approved by Ethics Committee of Women\u2019s Hospital, School of Medicine, Zhejiang University (IRB-20210092-R).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no conflicts of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"265"}}