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Clinical information and biochemical indicators of patients were collected from the inpatient electronic medical record system and analyzed retrospectively. Fundus photography, nerve conduction testing, and sensory threshold measurement were all conducted on the subjects. We measured the pulse wave velocity on both sides of the arm and ankle, then averaged the results. The enrolled cases were divided into two groups based on the baPWV: Group 1 (&lt;the reference cutoff value, n\u2009=\u2009160) and Group 2 (\u2265\u2009the reference cutoff value, n\u2009=\u2009162). The association between associated factors and baPWV abnormalities was investigated using a logistic regression model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Group 2 had higher Systolic Blood Pressure(SBP), Diastolic Blood Pressure (DBP), duration of diabetes, Fasting Plasma Glucose (FPG), Blood Urea Nitrogen (BUN) and Serum Uric Acid (SUA) than group 1 (all p\u2009&lt;\u20090.05). The prevalence of diabetic retinopathy, peripheral neuropathy and nephropathy in group 2 was higher compared to group 1 (p\u2009&lt;\u20090.05). After classifying subjects according to the presence or absence of diabetic complications, we found that the baPWV of the Diabetic Peripheral Neuropathy (DPN) group and Diabetic Nephropathy (DN) group was noticeably higher than that of non-DPN group and non-DN group, respectively (both p\u2009&lt;\u20090.05). The baPWV increased with the aggravation of Diabetic Retinopathy (DR) (p\u2009&lt;\u20090.05). Multivariate logistic regression analysis showed that DBP (OR 1.039, 95%CI 1.010\u20131.068 p\u2009=\u20090.008), duration of diabetes (OR 1.059, 95%CI 1.017\u20131.103 p\u2009=\u20090.006), FPG (OR 1.104, 95%CI 1.025\u20131.188 p\u2009=\u20090.009) and BUN (OR 1.128, 95%CI 1.001\u20131.270 p\u2009=\u20090.048) were all independently and positively associated with baPWV.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The baPWV is strongly associated with microvascular complications of T2DM. The DBP, duration of diabetes, FPG, and BUN were all independent associated factors of baPWV.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12902-023-01355-w","type":"journal-article","created":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T01:01:48Z","timestamp":1683162108000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Association between brachial-ankle pulse wave velocity and microvascular complications in type 2 diabetes mellitus"],"prefix":"10.1186","volume":"23","author":[{"given":"Yifei","family":"Pei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Shu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuting","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,5,4]]},"reference":[{"key":"1355_CR1","doi-asserted-by":"publisher","first-page":"107843","DOI":"10.1016\/j.diabres.2019.107843","volume":"157","author":"P Saeedi","year":"2019","unstructured":"Saeedi P, Petersohn I, Salpea P, Malanda B, Karuranga S, Unwin N, Colagiuri S, Guariguata L, Motala AA, Ogurtsova K et al: Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9(th) edition. 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Written informed consent of the subject and oral informed consent of the illiterate subject approved by the Ethics Committee of the Third Affiliated Hospital of Nanchang University were obtained after the study was explained to the subject in detail. All experiments and methods were carried out in accordance with the Declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"98"}}