{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T10:45:58Z","timestamp":1782729958336,"version":"3.54.5"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T00:00:00Z","timestamp":1782691200000},"content-version":"vor","delay-in-days":60,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Endocr Disord"],"DOI":"10.1186\/s12902-026-02243-9","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T10:13:38Z","timestamp":1777544018000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Thyroid disorders in idiopathic inflammatory myopathies: prevalence and related clinical scenarios"],"prefix":"10.1186","volume":"26","author":[{"given":"Linda","family":"Carli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Diomedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Cardelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Barsotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Fattorini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elenia","family":"Laurino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Tripoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Mosca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,30]]},"reference":[{"key":"2243_CR1","unstructured":"Endocrinol M. Thyroid diseases in elderly [Internet]. Review. 2011;36. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/22019751\/"},{"key":"2243_CR2","volume-title":"Hashimoto\u2019s Thyroiditis. Endocrinology","author":"WM Wiersinga","year":"2018","unstructured":"Wiersinga WM. Hashimoto\u2019s Thyroiditis. Endocrinology. Cham: Springer; 2018."},{"key":"2243_CR3","doi-asserted-by":"crossref","unstructured":"Knobel M. Etiopathology, clinical features, and treatment of diffuse and multinodular nontoxic goiters. J Endocrinol Invest. 2016;39:357\u201373.","DOI":"10.1007\/s40618-015-0391-7"},{"key":"2243_CR4","doi-asserted-by":"crossref","unstructured":"Antonelli A, Ferrari SM, Ragusa F, Elia G, Paparo SR, Ruffilli I, et al. Graves\u2019 disease: Epidemiology, genetic and environmental risk factors and viruses. Best Pract Res Clin Endocrinol Metab. 2020;34.","DOI":"10.1016\/j.beem.2020.101387"},{"issue":"4","key":"2243_CR5","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/S2213-8587(21)00027-9","volume":"9","author":"A Miranda-Filho","year":"2021","unstructured":"Miranda-Filho A, Lortet-Tieulent J, Bray F, Cao B, Franceschi S, Vaccarella S, et al. Thyroid cancer incidence trends by histology in 25 countries: a population-based study. Lancet Diabetes Endocrinol. 2021;9(4):225\u201334.","journal-title":"Lancet Diabetes Endocrinol"},{"key":"2243_CR6","doi-asserted-by":"crossref","unstructured":"Lichtiger A, Fadaei G, Tagoe CE. Autoimmune thyroid disease and rheumatoid arthritis: where the twain meet. Clin Rheumatol. 2024;43:895\u2013905.","DOI":"10.1007\/s10067-024-06888-6"},{"key":"2243_CR7","doi-asserted-by":"crossref","unstructured":"Watad A, Bragazzi NL, Damiani G, Nissan E, Comaneshter D, Cohen AD, et al. Dysthyroidism in dermato\/polymyositis patients: a case-control study. Eur J Clin Invest. 2021;51(5).","DOI":"10.1111\/eci.13460"},{"key":"2243_CR8","doi-asserted-by":"crossref","unstructured":"Lundberg IE, Miller FW, Tj\u00e4rnlund A, Bottai M. Diagnosis and classification of idiopathic inflammatory myopathies. J Int Med. Blackwell Publishing Ltd; 2016;280: 39\u201351.","DOI":"10.1111\/joim.12524"},{"key":"2243_CR9","doi-asserted-by":"crossref","unstructured":"Yoshida A, Li Y, Maroufy V, Kuwana M, Shaharir SS, Makol A, et al. Impaired health-related quality of life in idiopathic inflammatory myopathies: a cross-sectional analysis from the COVAD-2 e-survey. Rheumatol Adv Pract. 2024;8(2).","DOI":"10.1093\/rap\/rkae097"},{"key":"2243_CR10","unstructured":"Carli L, Tani C, Spera V, Vagelli R, Vagnani S, Mazzantini M, et al. Risk factors for osteoporosis and fragility fractures in patients with systemic lupus erythematosus."},{"key":"2243_CR11","doi-asserted-by":"crossref","unstructured":"Williams GR, Bassett JHD. Thyroid diseases and bone health. J Endocrinol Invest. Springer International Publishing. 2018;41: 99\u2013109.","DOI":"10.1007\/s40618-017-0753-4"},{"key":"2243_CR12","doi-asserted-by":"crossref","unstructured":"Paschou SA, Bletsa E, Stampouloglou PK, Tsigkou V, Valatsou A, Stefanaki K, et al. Thyroid disorders and cardiovascular manifestations: an update. Endocrine. Springer. 2022;75:672\u201383.","DOI":"10.1007\/s12020-022-02982-4"},{"key":"2243_CR13","unstructured":"Barsotti S, Saponaro C, Gaggini M, Talarico R, Bianchini E, Di Lascio N, et al. Cardiometabolic risk and subclinical vascular damage assessment in idiopathic inflammatory myopathies: a challenge for the clinician. Clin Exper Rheumatol. 2019:37."},{"key":"2243_CR14","unstructured":"Lundberg IE, Tj\u00e4rnlund A, Bottai M, Werth VP, Pilkington C, de Visser M, et al. European League Against Rheumatism\/American college of rheumatology classification criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups. In: Annals of the rheumatic diseases. 2017:1955\u201364."},{"key":"2243_CR15","doi-asserted-by":"crossref","unstructured":"Lins L, Carvalho FM. SF-36 total score as a single measure of health-related quality of life: Scoping review. SAGE Open Med. SAGE Publications Ltd. 2016;4.","DOI":"10.1177\/2050312116671725"},{"key":"2243_CR16","unstructured":"Bruce B, Fries JF, Health, and quality of life outcomes the stanford health assessment questionnaire. DimensionsPractical Applications Why assess Health-Related Quality of Life with the Health Assessment Questionnaire (HAQ)? [Internet]. 2003. Available from: http:\/\/www.hqlo.com\/content\/1\/1\/20."},{"key":"2243_CR17","unstructured":"Bjelland I, Dahl AA, Haug T, Neckelmann D. The validity of the hospital anxiety and depression scale an updated literature review."},{"key":"2243_CR18","doi-asserted-by":"crossref","unstructured":"Ilsley T, Howden EJ, Clinimetrics. Functional assessment of chronic illness therapy-fatigue (FACIT-Fatigue). Australian Physiotherapy Association. J Physioth. 2023;69:273\u20134.","DOI":"10.1016\/j.jphys.2023.03.005"},{"key":"2243_CR19","doi-asserted-by":"crossref","unstructured":"Bloise FF, Cordeiro A, Ortiga-Carvalho TM. Role of thyroid hormone in skeletal muscle physiology, J Endocrinol. BioScientifica Ltd. 2018: 236; R57\u201368.","DOI":"10.1530\/JOE-16-0611"},{"key":"2243_CR20","doi-asserted-by":"crossref","unstructured":"Simonides WS, Thelen MHM, Van Der Linden G, Muller C, Van Hardeveld A. C. Mechanism of Thyroid-hormone regulated expression of the SERCA genes in skeletal muscle: implications for thermogenesis, Bioscience Reports. 2001; 21.","DOI":"10.1023\/A:1013692023449"},{"key":"2243_CR21","unstructured":"Kiss E, Jakab G, Kranias EG, Edes I. Thyroid hormone-induced alterations in phospholamban protein expression regulatory effects on sarcoplasmic reticulum Ca2\u2019 Trans Myocard Relax [Internet]. Available from: http:\/\/ahajournals.org."},{"issue":"4","key":"2243_CR22","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1016\/j.arcmed.2005.11.001","volume":"37","author":"K Charalabopoulos","year":"2006","unstructured":"Charalabopoulos K, Mittari E, Peschos D, Golias C, Charalabopoulos A, Tsanou E, et al. Rare Association of Chronic Lymphocytic Thyroiditis with Dermatomyositis. Arch Med Res. 2006;37(4):563\u20135.","journal-title":"Arch Med Res"},{"issue":"6","key":"2243_CR23","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1007\/s00431-002-0947-3","volume":"161","author":"T Go","year":"2002","unstructured":"Go T, Mitsuyoshi I. Juvenile dermatomyositis associated with subclinical hypothyroidism due to auto-immune thyroiditis. Eur J Pediatr. 2002;161(6):358\u20139.","journal-title":"Eur J Pediatr"},{"key":"2243_CR24","doi-asserted-by":"crossref","unstructured":"Jenkins RC, Weetman AP. Review disease associations with autoimmune thyroid disease. Thyroid. 2002; 12.","DOI":"10.1089\/105072502320908312"},{"key":"2243_CR25","unstructured":"Paul S, Li L, Kalaga R, O\u2019dell J, Dannenbring RE, Swindells S, et al. Characterization of thyroglobulin-directed and polyreactive catalytic antibodies in autoimmune disease LinkOut-more resources other literature sources the lens-patent citations database [Internet]. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/9233652\/."},{"issue":"5","key":"2243_CR26","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1097\/MD.0b013e318156f9c2","volume":"86","author":"A Selva-O\u2019Callaghan","year":"2007","unstructured":"Selva-O\u2019Callaghan A, Redondo-Benito A, Trallero-Aragu\u00e1s E, Mart\u00ednez-G\u00f3mez X, Palou E, Vilardell-Tarres M. Clinical significance of thyroid disease in patients with inflammatory myopathy. Medicine. 2007;86(5):293\u20138.","journal-title":"Medicine"},{"issue":"8","key":"2243_CR27","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1007\/s10067-008-0904-2","volume":"27","author":"M Mosca","year":"2008","unstructured":"Mosca M, Carli L, d\u2019Ascanio A, Tani C, Talarico R, Baldini C, et al. Occurrence of organ-specific and systemic autoimmune diseases among the first- and second-degree relatives of Caucasian patients with connective tissue diseases: Report of data obtained through direct patient interviews. Clin Rheumatol. 2008;27(8):1045\u20138.","journal-title":"Clin Rheumatol"},{"issue":"6","key":"2243_CR28","doi-asserted-by":"publisher","first-page":"896","DOI":"10.1016\/j.metabol.2009.10.010","volume":"59","author":"A Antonelli","year":"2010","unstructured":"Antonelli A, Fallahi P, Mosca M, Ferrari SM, Ruffilli I, Corti A, et al. Prevalence of thyroid dysfunctions in systemic lupus erythematosus. Metabolism. 2010;59(6):896\u2013900.","journal-title":"Metabolism"},{"key":"2243_CR29","unstructured":"Danieli MG, Rossetti L, Fraticelli P, Malcangi G, Testa I, Danieli G. Autoimmune thyroid diseases in patients with undifferentiated connective tissue disease."},{"key":"2243_CR30","doi-asserted-by":"crossref","unstructured":"Liu YJ, Miao HB, Lin S, Chen Z. Association between rheumatoid arthritis and thyroid dysfunction: a meta-analysis and systematic review. Front Endocrinol. Frontiers Media. 2022;13.","DOI":"10.3389\/fendo.2022.1015516"},{"key":"2243_CR31","unstructured":"17, Gir\u00f3n-P\u00efllado M, Saavedra-Gonz\u00e1lez V, Atisha-Fregoso Y, Barraza G, et al. Autoimmune thyroid disease in primary Sjogren\u2019s syndrome real-life screening practice and clinical outcomes."},{"key":"2243_CR32","doi-asserted-by":"crossref","unstructured":"Cherim A, Petca RC, Dumitrascu MC, Petca A, Candrea E, Sandru F. Thyroid disorders in systemic sclerosis: a comprehensive review. J Clin Med. Multidisciplinary Digital Publishing Institute (MDPI). 2024;13.","DOI":"10.3390\/jcm13020415"},{"issue":"4","key":"2243_CR33","doi-asserted-by":"publisher","first-page":"594","DOI":"10.3748\/wjg.v13.i4.594","volume":"13","author":"MH Emami","year":"2007","unstructured":"Emami MH, Raisi M, Amini J, Daghaghzadeh H. Achalasia and thyroid disease. World J Gastroenterol. 2007;13(4):594\u20139.","journal-title":"World J Gastroenterol"},{"issue":"3","key":"2243_CR34","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1111\/j.1442-2050.2011.01249.x","volume":"25","author":"JD Booy","year":"2012","unstructured":"Booy JD, Takata J, Tomlinson G, Urbach DR. The prevalence of autoimmune disease in patients with esophageal achalasia. Dis Esophagus. 2012;25(3):209\u201313.","journal-title":"Dis Esophagus"},{"issue":"7","key":"2243_CR35","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1007\/s40618-014-0085-6","volume":"37","author":"M \u0130lhan","year":"2014","unstructured":"\u0130lhan M, Arabaci E, Turgut S, Karaman O, Danalioglu A, Tasan E. Esophagus motility in overt hypothyroidism. J Endocrinol Invest. 2014;37(7):639\u201344.","journal-title":"J Endocrinol Invest"},{"key":"2243_CR36","doi-asserted-by":"crossref","unstructured":"Cox M, Sandler RD, Matucci-Cerinic M, Hughes M. Bone health in idiopathic inflammatory myopathies. Autoimm Rev. Elsevier. 2021;20.","DOI":"10.1016\/j.autrev.2021.102782"},{"key":"2243_CR37","doi-asserted-by":"crossref","unstructured":"Vincze A, Bodoki L, Szab\u00f3 K, Nagy-Vincze M, Szalm\u00e1s O, Varga J, et al. The risk of fracture and prevalence of osteoporosis is elevated in patients with idiopathic inflammatory myopathies: Cross-sectional study from a single Hungarian center. BMC Musculoskelet Disord. 2020;21(1).","DOI":"10.1186\/s12891-020-03448-2"},{"issue":"4","key":"2243_CR38","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/j.ando.2017.11.004","volume":"80","author":"M Yazidi","year":"2019","unstructured":"Yazidi M, Chihaoui M, Oueslati H, Chaker F, Rjeb O, Rjaibi S, et al. Cardiothyreosis: Prevalence and risk factors. Ann Endocrinol (Paris). 2019;80(4):211\u20135.","journal-title":"Ann Endocrinol (Paris)"},{"issue":"1","key":"2243_CR39","doi-asserted-by":"publisher","first-page":"101732","DOI":"10.1016\/j.beem.2023.101732","volume":"37","author":"T Watt","year":"2023","unstructured":"Watt T, Christoffersen T, Brogaard MB, Bjorner JB, Bentzen J, Hahn CH, et al. Quality of life in thyroid cancer. Best Pract Res Clin Endocrinol Metab. 2023;37(1):101732.","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"2243_CR40","doi-asserted-by":"crossref","unstructured":"Uslar V, Becker C, Weyhe D, Tabriz N. Thyroid disease-specific quality of life questionnaires - a systematic review, Endocrinology, Diabetes and Metabolism. John Wiley and Sons Inc. 2022; 5.","DOI":"10.1002\/edm2.357"},{"key":"2243_CR41","doi-asserted-by":"publisher","first-page":"S27","DOI":"10.1210\/clinem\/dgac230","volume":"107","author":"A Sharma","year":"2022","unstructured":"Sharma A, Stan MN, Rootman DB. Measuring Health-Related Quality of Life in Thyroid Eye Disease. J Clin Endocrinol Metab. 2022;107:S27\u201335.","journal-title":"J Clin Endocrinol Metab"}],"container-title":["BMC Endocrine Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12902-026-02243-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12902-026-02243-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12902-026-02243-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T09:59:47Z","timestamp":1782727187000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12902-026-02243-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,30]]},"references-count":41,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["2243"],"URL":"https:\/\/doi.org\/10.1186\/s12902-026-02243-9","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-7517793\/v1","asserted-by":"object"}]},"ISSN":["1472-6823"],"issn-type":[{"value":"1472-6823","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,30]]},"assertion":[{"value":"2 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 April 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"the study was approved by the local Ethics Committee [(Comitato Etico Regionale per la Sperimentazione Clinica della Regione Toscana \u2013 AREA VASTA NORD OVEST (Regional Ethics Committee for Clinical Research of the Tuscany Region \u2013 NORTH-WEST AREA); Institute: Unit\u00e0 Sanitaria Locale Toscana Nord Ovest (Local Health Authority of North-West Tuscany)], and the committee\u2019s reference number is 20070.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"all patients provided consent for data publication.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Patient consent for publication"}},{"value":"All participants signed an informed consent prior to inclusion in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"185"}}