{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T14:01:00Z","timestamp":1793196060155,"version":"4.5.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,4,5]],"date-time":"2018-04-05T00:00:00Z","timestamp":1522886400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Oral Health"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1186\/s12903-018-0516-4","type":"journal-article","created":{"date-parts":[[2018,4,19]],"date-time":"2018-04-19T14:46:34Z","timestamp":1524149194000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":68,"title":["Consequences of early extraction of compromised first permanent molar: a systematic review"],"prefix":"10.1186","volume":"18","author":[{"given":"Afnan M.","family":"Saber","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doua H.","family":"Altoukhi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariam F.","family":"Horaib","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azza A.","family":"El-Housseiny","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Najlaa M.","family":"Alamoudi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heba J.","family":"Sabbagh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,4,5]]},"reference":[{"issue":"4","key":"516_CR1","doi-asserted-by":"publisher","first-page":"55","DOI":"10.5539\/ijb.v5n4p55","volume":"5","author":"D Ozdemir","year":"2013","unstructured":"Ozdemir D. Dental Caries : The most common disease worldwide and preventive strategies. Int J Biol. 2013;5(4):55\u201361.","journal-title":"Int J Biol"},{"key":"516_CR2","unstructured":"World Health Organization (WHO). Oral Health. World Health Organization. 2012 [Available from: http:\/\/www.who.int\/mediacentre\/factsheets\/fs318\/en\/ [Accessed 15-2-2016 2016]."},{"key":"516_CR3","unstructured":"American Dental Association (ADA). Tooth eruption. J Am Dent Assoc. 2006 [Available from: http:\/\/www.ada.org\/~\/media\/ADA\/Publications\/Files\/patient_58.ashx [Accessed 15\u20132-2016 2016]."},{"issue":"3","key":"516_CR4","first-page":"77","volume":"1","author":"M ElSheikh","year":"2015","unstructured":"ElSheikh M, Ali A. Planned extraction of first permanent molars during late childhood: a clinical note and mini-review. Dent Oral Craniofac Res. 2015;1(3):77\u201380.","journal-title":"Dent Oral Craniofac Res"},{"issue":"6","key":"516_CR5","doi-asserted-by":"publisher","first-page":"304","DOI":"10.12968\/denu.2001.28.6.304","volume":"28","author":"DS Gill","year":"2001","unstructured":"Gill DS, Lee RT, Tredwin CJ. Treatment planning for the loss of first permanent molars. Dent Update. 2001;28(6):304\u20138.","journal-title":"Dent Update"},{"issue":"5","key":"516_CR6","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1034\/j.1600-0528.2003.00016.x","volume":"31","author":"KR Ekstrand","year":"2003","unstructured":"Ekstrand KR, Christiansen J, Christiansen ME. Time and duration of eruption of first and second permanent molars: a longitudinal investigation. Community Dent Oral Epidemiol. 2003;31(5):344\u201350.","journal-title":"Community Dent Oral Epidemiol"},{"issue":"1","key":"516_CR7","first-page":"138","volume":"2","author":"AE Telli","year":"1989","unstructured":"Telli AE, Aytan S. Changes in the dental arch due to obligatory early extraction of first permanent molars. Turk Ortodonti Dergisi. 1989;2(1):138\u201343.","journal-title":"Turk Ortodonti Dergisi"},{"issue":"4","key":"516_CR8","first-page":"719","volume":"22","author":"N Mantel","year":"1959","unstructured":"Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst. 1959;22(4):719\u201348.","journal-title":"J Natl Cancer Inst"},{"issue":"7414","key":"516_CR9","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","volume":"327","author":"JP Higgins","year":"2003","unstructured":"Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557\u201360.","journal-title":"BMJ"},{"issue":"4","key":"516_CR10","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1016\/j.jclinepi.2007.11.008","volume":"61","author":"E von Elm","year":"2008","unstructured":"von Elm E, Altman DG, Egger M, Pocock SJ, Gotzsche PC, Vandenbroucke JP. The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. J Clin Epidemiol. 2008;61(4):344\u20139.","journal-title":"J Clin Epidemiol"},{"issue":"7183","key":"516_CR11","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1136\/bmj.318.7183.593","volume":"318","author":"PG Shekelle","year":"1999","unstructured":"Shekelle PG, Woolf SH, Eccles M, Grimshaw J. Clinical guidelines: developing guidelines. BMJ. 1999;318(7183):593\u20136.","journal-title":"BMJ"},{"issue":"2","key":"516_CR12","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1016\/0002-9416(62)90114-8","volume":"48","author":"DB Ast","year":"1962","unstructured":"Ast DB, Allaway N, Draker HL. The prevalence of malocclusion, related to dental caries and lost first permanent molars, in a fluoridated city and a fluoride-deficient city. Am J Orthod. 1962;48(2):106\u201313.","journal-title":"Am J Orthod"},{"issue":"1","key":"516_CR13","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.ajodo.2004.10.010","volume":"129","author":"S Ay","year":"2006","unstructured":"Ay S, Agar U, Bicakci AA, Kosger HH. Changes in mandibular third molar angle and position after unilateral mandibular first molar extraction. Am J Orthod Dentofac Orthop. 2006;129(1):36\u201341.","journal-title":"Am J Orthod Dentofac Orthop"},{"issue":"5","key":"516_CR14","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1111\/j.1365-263X.2007.00849.x","volume":"17","author":"B Jalevik","year":"2007","unstructured":"Jalevik B, Moller M. Evaluation of spontaneous space closure and development of permanent dentition after extraction of hypomineralized permanent first molars. Int J Paediatr Dent. 2007;17(5):328\u201335.","journal-title":"Int J Paediatr Dent"},{"issue":"4","key":"516_CR15","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/0300-5712(88)90026-7","volume":"16","author":"SJ Oliver","year":"1988","unstructured":"Oliver SJ, Dummer PM, Oliver RG, Hicks R, Addy M, Kingdon A, Shaw WC. The relationship between loss of first permanent molar teeth and the prevalence of caries and restorations in adjacent teeth: a study of 15-16- year-old children. J Dent. 1988;16(4):155\u20139.","journal-title":"J Dent"},{"issue":"3","key":"516_CR16","first-page":"3","volume":"8","author":"AFV R\u00e3ducanu","year":"2009","unstructured":"R\u00e3ducanu AFV, Herteliu C, R\u00e3ducanu M. Prevalence of loss of permanent first molars in a group of Romanian children and adolescents. Oral Health Dent Manag. 2009;8(3):3\u201310.","journal-title":"Oral Health Dent Manag"},{"issue":"1","key":"516_CR17","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1093\/ejo\/cjv029","volume":"38","author":"TK Teo","year":"2015","unstructured":"Teo TK, Ashley PF, Derrick D. Lower first permanent molars: developing better predictors of spontaneous space closure. Eur J Orthod. 2015;38(1):90\u20135.","journal-title":"Eur J Orthod"},{"issue":"4","key":"516_CR18","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1007\/s40368-013-0042-7","volume":"14","author":"TK Teo","year":"2013","unstructured":"Teo TK, Ashley PF, Parekh S, Noar J. The evaluation of spontaneous space closure after the extraction of first permanent molars. Eur Arch Paediatr Dent. 2013;14(4):207\u201312.","journal-title":"Eur Arch Paediatr Dent"},{"issue":"5","key":"516_CR19","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1016\/j.ajodo.2005.02.026","volume":"130","author":"I Yavuz","year":"2006","unstructured":"Yavuz I, Baydas B, Ikbal A, Dagsuyu IM, Ceylan I. Effects of early loss of permanent first molars on the development of third molars. Am J Orthod Dentofac Orthop. 2006;130(5):634\u20138.","journal-title":"Am J Orthod Dentofac Orthop"},{"issue":"6","key":"516_CR20","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1590\/S2176-94512010000600013","volume":"15","author":"D Normando","year":"2010","unstructured":"Normando D, Cavacami C. The influence of bilateral lower first permanent molar loss on dentofacial morfology \u2013 a cephalometric study. Dental Press J Orthod. 2010;15(6):100\u20136.","journal-title":"Dental Press J Orthod"},{"issue":"3","key":"516_CR21","first-page":"161","volume":"4","author":"A Rahhal","year":"2014","unstructured":"Rahhal A. Extraction timing of heavily destructed upper first permanent molars. Czas Stomatol. 2014;4(3):161\u20138.","journal-title":"Czas Stomatol"},{"issue":"9","key":"516_CR22","first-page":"330","volume":"39","author":"GJ Pell","year":"1933","unstructured":"Pell GJ, Gregory GT. Impacted mandibular third molars: classification and modified technique for removal. Dent Digest. 1933;39(9):330\u201388.","journal-title":"Dent Digest"},{"issue":"2","key":"516_CR23","first-page":"211","volume":"45","author":"A Demirjian","year":"1973","unstructured":"Demirjian A, Goldstein H, Tanner JM. A new system of dental age assessment. Hum Biol. 1973;45(2):211\u201327.","journal-title":"Hum Biol"},{"issue":"7","key":"516_CR24","doi-asserted-by":"publisher","first-page":"E14","DOI":"10.1038\/bdj.2007.679","volume":"203","author":"S Albadri","year":"2007","unstructured":"Albadri S, Zaitoun H, McDonnell ST, Davidson LE. Extraction of first permanent molar teeth: results from three dental hospitals. Br Dent J. 2007;203(7):E14. discussion 408-9","journal-title":"Br Dent J"},{"issue":"4","key":"516_CR25","first-page":"272","volume":"16","author":"M Eichenberger","year":"2015","unstructured":"Eichenberger M, Erb J, Zwahlen M, Schatzle M. The timing of extraction of non-restorable first permanent molars: a systematic review. Eur J Paediatr Dent. 2015;16(4):272\u20138.","journal-title":"Eur J Paediatr Dent"},{"issue":"9","key":"516_CR26","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1038\/sj.bdj.4802759","volume":"131","author":"JJ Crabb","year":"1971","unstructured":"Crabb JJ, Rock WP. Treatment planning in relation to the first permanent molar. Br Dent J. 1971;131(9):396\u2013401.","journal-title":"Br Dent J"},{"issue":"3","key":"516_CR27","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1177\/0022034515615857","volume":"95","author":"K Carter","year":"2016","unstructured":"Carter K, Worthington S. Predictors of third molar impaction: a systematic review and meta-analysis. J Dent Res. 2016;95(3):267\u201376.","journal-title":"J Dent Res"},{"issue":"1","key":"516_CR28","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.sjdr.2015.04.005","volume":"7","author":"M Hatem","year":"2016","unstructured":"Hatem M, Bugaighis I, Taher EM. Pattern of third molar impaction in Libyan population: a retrospective radiographic study. Saudi J Dent Res. 2016;7(1):7\u201312.","journal-title":"Saudi J Dent Res"},{"issue":"3","key":"516_CR29","doi-asserted-by":"crossref","first-page":"e388","DOI":"10.18295\/2075-0528.1604","volume":"14","author":"SM Al-Anqudi","year":"2014","unstructured":"Al-Anqudi SM, Al-Sudairy S, Al-Hosni A, Al-Maniri A. Prevalence and pattern of third molar impaction: a retrospective study of radiographs in Oman. Sultan Qaboos Univ Med J. 2014;14(3):e388\u201392.","journal-title":"Sultan Qaboos Univ Med J"},{"issue":"3","key":"516_CR30","first-page":"195","volume":"24","author":"ES Abu Aihaija","year":"2000","unstructured":"Abu Aihaija ES, McSheny PF, Richardson AA. Cephalometric study of the effect of extraction of lower first permanent molars. J Clin Pediatr Dent. 2000;24(3):195\u20138.","journal-title":"J Clin Pediatr Dent"},{"key":"516_CR31","first-page":"1252","volume-title":"Nelson textbook of pediatrics","author":"N Tinanoff","year":"2011","unstructured":"Tinanoff N. Malocclusion. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, editors. Nelson textbook of pediatrics. 19th ed. Philadelphia: Saunders Elsevier; 2011. p. 1252.","edition":"19"},{"issue":"237","key":"516_CR32","first-page":"1","volume":"10","author":"L Dimberg","year":"2015","unstructured":"Dimberg L. Malocclusions and Quality of life. Cross-sectional and longitudinal studies in children. Swed Dent J Suppl. 2015;10(237):1\u201388.","journal-title":"Swed Dent J Suppl"}],"container-title":["BMC Oral Health"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12903-018-0516-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12903-018-0516-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12903-018-0516-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T19:47:29Z","timestamp":1751572049000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcoralhealth.biomedcentral.com\/articles\/10.1186\/s12903-018-0516-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,5]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["516"],"URL":"https:\/\/doi.org\/10.1186\/s12903-018-0516-4","relation":{},"ISSN":["1472-6831"],"issn-type":[{"value":"1472-6831","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,5]]},"assertion":[{"value":"27 November 2016","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 March 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 April 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Not applicable.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"59"}}