{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T09:07:42Z","timestamp":1792919262781,"version":"4.5.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,7,3]],"date-time":"2020-07-03T00:00:00Z","timestamp":1593734400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,7,3]],"date-time":"2020-07-03T00:00:00Z","timestamp":1593734400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Oral Health"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The aim of this study was to evaluate chemosensory function and oral disorders in patients with primary Sj\u00f6gren\u2019s syndrome (pSS) and to compare these findings with those of age- and gender-matched healthy controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This comparative cross-sectional study included 58 patients with primary Sj\u00f6gren\u2019s syndrome (pSS) and 55 age- and gender-matched healthy controls. Olfactory and gustatory function, burning sensations in the tongue (BST) and halitosis were assessed. Oral health-related quality of life (OHRQoL) was evaluated using the short-form Oral Health Impact Profile (OHIP-14).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Patients with pSS had significantly lower self-reported visual analogue scale (VAS) smell score (8.6\u2009\u00b1\u20092.2 vs. 9.6\u2009\u00b1\u20090.7,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.016) and VAS taste score (8.5\u00a0\u00b1 2.1 vs.\u00a09.5\u2009\u00b1\u20090.7,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.014) than healthy controls. A greater proportion of patients with pSS had anosmia (3.8% vs. 0.0%) or hyposmia (36.5% vs. 13.2%) and ageusia for basic tastes: sweetness (34.0% vs. 7.5%), sourness (10.6% vs. 0.0), saltiness (10.0% vs. 5.7%) or bitterness (19.1% vs. 1.9%) as evaluated using Sniffin Sticks test and taste stripts, respectively. A higher proportion of pSS patients complained of dysgeusia (52.6% vs. 9.4%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001) and BST (45.6% vs. 0.0%, p\u2009&lt;\u20090.0001), while similar number of patients with pSS and controls reported halitosis (31.6% vs. 28.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.434). The mean OHIP-14 score was significantly higher in patients with pSS (6.8\u2009\u00b1\u20097.0 vs. 2.3\u2009\u00b1\u20098.5,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) indicating patients\u2019 poorer OHRQoL compared with controls.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The majority of patients with pSS had impaired chemosensory function and indicators of oral health in comparison with the age- and gender-matched healthy controls. Further studies of oral hygiene habits and dietary intake of these patients are needed to ensure better management of oral health problems in patients with pSS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12903-020-01169-5","type":"journal-article","created":{"date-parts":[[2020,7,3]],"date-time":"2020-07-03T05:05:05Z","timestamp":1593752705000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Chemosensory dysfunction, Oral disorders and Oral health-related quality of life in patients with primary Sj\u00f6gren\u2019s syndrome: comparative cross-sectional study"],"prefix":"10.1186","volume":"20","author":[{"given":"Mirjana","family":"\u0160ijan Gobelji\u0107","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vera","family":"Mili\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2279-9197","authenticated-orcid":false,"given":"Nada","family":"Pejnovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nemanja","family":"Damjanov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,7,3]]},"reference":[{"key":"1169_CR1","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S0140-6736(05)66990-5","volume":"366","author":"RI Fox","year":"2005","unstructured":"Fox RI. 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