{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T09:50:46Z","timestamp":1785837046553,"version":"3.56.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,1,23]],"date-time":"2020-01-23T00:00:00Z","timestamp":1579737600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,23]],"date-time":"2020-01-23T00:00:00Z","timestamp":1579737600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Oral Health"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>The purpose of this research was to investigate the effects of disinfection and three different sterilization methods on the dimensional changes and mechanical properties of three-dimensional (3D) printed surgical guide for implant therapy. The objective was to assess the effects of sterilization procedures in 3D printed drill guide templates with destructive and non-destructive material testing.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Fifteen identical drill guide templates were produced using a 3D printer. The surgical guides were classified into five groups: three controls, three disinfected (4% Gigasept\u00ae, 60\u2009min), three plasma sterilized, three autoclave sterilized (+\u20091\u2009bar, 121\u2009\u00b0C, 20\u2009min), and three autoclave sterilized (+\u20092\u2009bar, 134\u2009\u00b0C, 10\u2009min).<\/jats:p>\n                <jats:p>The templates were digitalized with a Steinbichler SCAN ST 3D scanner. Length was measured under an SZX16 stereomicroscope. A scanning electron microscope was used to study the surface morphology of the drill templates. The hardness, and flexural and compressive strength were measured to assess any changes in the physical characteristics of the material caused by sterilization. The drill guide templates were also examined with a Dage XiDAT 6600 X-ray. During the X-ray examinations, the following parameters were used: 100\u2009kV voltage, 128 AVG averaging, 0.8\u2009W power. One-way analysis of variance (ANOVA) was used to detect the difference between groups.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Evaluation of the hardness measurements of the various specimens shows that the hardness of the material was not changed by the plasma sterilization (<jats:italic>p<\/jats:italic>\u00a0=\u20090.0680), steam sterilization on 121\u2009\u00b0C (<jats:italic>p<\/jats:italic>\u00a0=\u20090.6033) or disinfection process (<jats:italic>p<\/jats:italic>\u00a0=\u20090.1399). The statistical analysis revealed significant difference in hardness strength of the autoclave sterilized (134\u2009\u00b0C) specimens (<jats:italic>p<\/jats:italic>\u00a0=\u20090.0002). There was no significant difference between the goups regarding the scanning electron microscopic and stereomicroscopic examinations. There was no significant difference regarding the X-ray visibility of the templates to the effect of the disinfection (<jats:italic>p<\/jats:italic>\u00a0=\u20090.7844), plasma sterilization (<jats:italic>p<\/jats:italic>\u00a0=\u20090.4091) and steam sterilization on 121\u2009\u00b0C (<jats:italic>p<\/jats:italic>\u00a0=\u20090.9277) and steam sterilization on 131\u2009\u00b0C (<jats:italic>p<\/jats:italic>\u00a0=\u20090.093). The effect of the sterilization was the same in case of both flexural and compressive strength of the material.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Our findings indicate that plasma sterilization and steam sterilization at 121\u2009\u00b0C were both suitable for sterilizing the tested 3D printed surgical guides.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12903-020-1005-0","type":"journal-article","created":{"date-parts":[[2020,1,23]],"date-time":"2020-01-23T16:02:42Z","timestamp":1579795362000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":79,"title":["Effects of disinfection and sterilization on the dimensional changes and mechanical properties of 3D printed surgical guides for implant therapy \u2013 pilot study"],"prefix":"10.1186","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4084-6556","authenticated-orcid":false,"given":"Gr\u00e9ta","family":"T\u00f6r\u00f6k","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e9ter","family":"Gombocz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eszter","family":"Bogn\u00e1r","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e9ter","family":"Nagy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elek","family":"Dinya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Kisp\u00e9lyi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e9ter","family":"Hermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,1,23]]},"reference":[{"key":"1005_CR1","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1007\/s13191-011-0104-7","volume":"12","author":"E Moslehifard","year":"2012","unstructured":"Moslehifard E, Nokar S. 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Ethics approval is not required for in vitro testing at Semmelweis University. Ethics approval is only required for animal and human clinical research. The name of the IRB is Semmelweis University Regional and Institutional Committee of Science and Research Ethics. The relevant legislation is Goverment Decree 235\/2009 \u2013 on rules of authorization of medical research involving human subjects, clinical study of investigational medicinal products intended for human use, and clinical investigation of medical devices intended for human use and the Act CLIV\/1997 \u2013 on healthcare.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"19"}}