{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:45:19Z","timestamp":1792025119408,"version":"4.4.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,8,11]],"date-time":"2021-08-11T00:00:00Z","timestamp":1628640000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,8,11]],"date-time":"2021-08-11T00:00:00Z","timestamp":1628640000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Oral Health"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>It is well known that periodontitis can stimulate thickening of the maxillary sinus mucosa, but the association between periodontitis status and the degree of maxillary sinus mucosal thickening (maxMT) has not been reported. The objectives of this study were to investigate the effect of periodontal status of maxillary molars on the degree of maxMT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective analysis of cone-beam computed tomographic (CBCT) images of 203 periodontitis cases with maxMT. Parameters related to periodontitis in maxillary molars were measured and recorded on CBCT images. The dimension and length of the maxMT were also recorded. Multiple linear regression analysis was used to identify periodontal factors influencing the severity of maxMT, and multivariate logistic regression analysis was used to identify the odds ratio of these factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The factors affecting the degree of maxMT were mainly the amount of alveolar bone loss (ABL) and the minimum residual alveolar bone height (miniRABH). Compared to mild ABL, severe and moderate ABL were more likely to display severe maxMT. And the lower the miniRABH, the more severe the maxMT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The severity of periodontal status of maxillary molars can influence the degree of maxMT.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12903-021-01737-3","type":"journal-article","created":{"date-parts":[[2021,8,11]],"date-time":"2021-08-11T09:03:44Z","timestamp":1628672624000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Association between periodontal status and degree of maxillary sinus mucosal thickening: a retrospective CBCT study"],"prefix":"10.1186","volume":"21","author":[{"given":"Tianyi","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengquan","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,8,11]]},"reference":[{"issue":"9499","key":"1737_CR1","doi-asserted-by":"publisher","first-page":"1809","DOI":"10.1016\/S0140-6736(05)67728-8","volume":"366","author":"BL Pihlstrom","year":"2005","unstructured":"Pihlstrom BL, Michalowicz BS, Johnson NW. Periodontal diseases. The Lancet. 2005;366(9499):1809\u201320.","journal-title":"The Lancet"},{"issue":"11","key":"1737_CR2","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1177\/0022034514552491","volume":"93","author":"NJ Kassebaum","year":"2014","unstructured":"Kassebaum NJ, Bernab\u00e9 E, Dahiya M, Bhandari B, Murray CJL, Marcenes W. Global burden of severe periodontitis in 1990\u20132010. J Dent Res. 2014;93(11):1045\u201353.","journal-title":"J Dent Res"},{"issue":"7","key":"1737_CR3","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1038\/s41415-019-0794-5","volume":"227","author":"PM Preshaw","year":"2019","unstructured":"Preshaw PM, Bissett SM. Periodontitis and diabetes. Brit Dent J. 2019;227(7):577\u201384.","journal-title":"Brit Dent J"},{"issue":"3","key":"1737_CR4","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1111\/jcpe.13189","volume":"47","author":"M Sanz","year":"2020","unstructured":"Sanz M, Marco Del Castillo A, Jepsen S, Gonzalez Juanatey JR, Aiuto F, Bouchard P, Chapple I, Dietrich T, Gotsman I, Graziani F, et al. Periodontitis and cardiovascular diseases: consensus report. J Clin Periodontol. 2020;47(3):268\u201388.","journal-title":"J Clin Periodontol"},{"issue":"6","key":"1737_CR5","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1111\/idj.12186","volume":"65","author":"S Ren","year":"2015","unstructured":"Ren S, Zhao H, Liu J, Wang Q, Pan Y. Significance of maxillary sinus mucosal thickening in patients with periodontal disease. Int Dent J. 2015;65(6):303\u201310.","journal-title":"Int Dent J"},{"issue":"3","key":"1737_CR6","doi-asserted-by":"publisher","first-page":"1175","DOI":"10.1007\/s00784-017-2206-z","volume":"22","author":"AWK Yeung","year":"2018","unstructured":"Yeung AWK, Tanaka R, Khong P, von Arx T, Bornstein MM. Frequency, location, and association with dental pathology of mucous retention cysts in the maxillary sinus. A radiographic study using cone beam computed tomography (CBCT). Clin Oral Invest. 2018;22(3):1175\u201383.","journal-title":"Clin Oral Invest"},{"issue":"4","key":"1737_CR7","doi-asserted-by":"publisher","first-page":"251","DOI":"10.4103\/1735-3327.261131","volume":"16","author":"V Apparaju","year":"2019","unstructured":"Apparaju V, Velamati SC, Karnati L, Salahshoor A, Nateghi F, Vaddamanu SK. Does residual bone thickness apical to periodontal defect play a major role in maxillary sinus mucous membrane thickness: a cone\u2014beam computed tomography\u2014assisted retrospective study. Dent Res J. 2019;16(4):251\u20136.","journal-title":"Dent Res J"},{"issue":"5","key":"1737_CR8","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1902\/jop.2011.110376","volume":"83","author":"S Phothikhun","year":"2012","unstructured":"Phothikhun S, Suphanantachat S, Chuenchompoonut V, Nisapakultorn K. Cone-beam computed tomographic evidence of the association between periodontal bone loss and mucosal thickening of the maxillary sinus. J Periodontol. 2012;83(5):557\u201364.","journal-title":"J Periodontol"},{"issue":"7","key":"1737_CR9","doi-asserted-by":"publisher","first-page":"1275","DOI":"10.1016\/j.joms.2015.01.039","volume":"73","author":"L Schwarz","year":"2015","unstructured":"Schwarz L, Schiebel V, Hof M, Ulm C, Watzek G, Pommer B. Risk factors of membrane perforation and postoperative complications in sinus floor elevation surgery: review of 407 augmentation procedures. J Oral Maxil Surg. 2015;73(7):1275\u201382.","journal-title":"J Oral Maxil Surg"},{"issue":"1","key":"1737_CR10","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1016\/j.tripleo.2010.02.038","volume":"110","author":"Y Manor","year":"2010","unstructured":"Manor Y, Mardinger O, Bietlitum I, Nashef A, Nissan J, Chaushu G. Late signs and symptoms of maxillary sinusitis after sinus augmentation. Oral Surg Oral Med Oral Pathol Oral Radiol Endodont. 2010;110(1):e1\u20134.","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endodont"},{"key":"1737_CR11","doi-asserted-by":"crossref","unstructured":"Qin Y, Shu G, Xu T. Evaluation of the relationship between maxillary sinus wall and maxillary canines and posterior teeth using cone-beam computed tomography. Med Sci Monitor. 2020;26:e925384.","DOI":"10.12659\/MSM.925384"},{"issue":"1","key":"1737_CR12","doi-asserted-by":"publisher","first-page":"6","DOI":"10.5577\/intdentres.2017.vol7.no1.2","volume":"7","author":"C Aktuna Belgin","year":"2017","unstructured":"Aktuna Belgin C, Adiguzel O, Bud M, Colak M, Akkus Z. Mandibular buccal bone thickness in southeastern Anatolian people: a cone-beam computed tomography study. International dental research. 2017;7(1):6.","journal-title":"International dental research"},{"issue":"6","key":"1737_CR13","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1259\/dmfr\/54316470","volume":"33","author":"K Honda","year":"2004","unstructured":"Honda K, Arai Y, Kashima M, Takano Y, Sawada K, Ejima K, Iwai K. Evaluation of the usefulness of the limited cone-beam CT (3DX) in the assessment of the thickness of the roof of the glenoid fossa of the temporomandibular joint. Dento-Maxillo-Facial Radiol. 2004;33(6):391.","journal-title":"Dento-Maxillo-Facial Radiol"},{"issue":"1","key":"1737_CR14","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1007\/s00784-018-2418-x","volume":"23","author":"U Aksoy","year":"2019","unstructured":"Aksoy U, Orhan K. Association between odontogenic conditions and maxillary sinus mucosal thickening: a retrospective CBCT study. Clin Oral Invest. 2019;23(1):123\u201331.","journal-title":"Clin Oral Invest"},{"issue":"11","key":"1737_CR15","doi-asserted-by":"publisher","first-page":"1429","DOI":"10.1002\/JPER.19-0391","volume":"91","author":"B Zhang","year":"2020","unstructured":"Zhang B, Wei Y, Cao J, Xu T, Zhen M, Yang G, Chung KH, Hu W. Association between the dimensions of the maxillary sinus membrane and molar periodontal status: a retrospective CBCT study. J Periodontol. 2020;91(11):1429\u201335.","journal-title":"J Periodontol"},{"issue":"4","key":"1737_CR16","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1007\/s00405-008-0786-6","volume":"266","author":"CA Cagici","year":"2009","unstructured":"Cagici CA, Yilmazer C, Hurcan C, Ozer C, Ozer F. Appropriate interslice gap for screening coronal paranasal sinus tomography for mucosal thickening. Eur Arch Oto-Rhino-L. 2009;266(4):519\u201325.","journal-title":"Eur Arch Oto-Rhino-L"},{"issue":"9","key":"1737_CR17","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1902\/jop.1991.62.9.570","volume":"62","author":"E Hausmann","year":"1991","unstructured":"Hausmann E, Allen K, Clerehugh V. What alveolar crest level on a bite-wing radiograph represents bone loss? J Periodontol. 1991;62(9):570\u20132.","journal-title":"J Periodontol"},{"key":"1737_CR18","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1111\/j.1600-051X.1975.tb01734.x","volume":"2","author":"S Hamp","year":"1975","unstructured":"Hamp S, Nyman S, Lindhe J. Periodontal treatment of multirooted teeth. Results after 5 years. J Clin Periodontol. 1975;2:126\u201335.","journal-title":"J Clin Periodontol"},{"issue":"3","key":"1737_CR19","first-page":"145","volume":"19","author":"J Zhu","year":"2016","unstructured":"Zhu J, Ouyang XY. Assessing maxillary molar furcation involvement by cone beam computed tomography. Chin J Dent Res. 2016;19(3):145.","journal-title":"Chin J Dent Res"},{"issue":"3","key":"1737_CR20","doi-asserted-by":"publisher","first-page":"e80","DOI":"10.1016\/j.tripleo.2009.10.031","volume":"109","author":"J Vallo","year":"2010","unstructured":"Vallo J, Suominen-Taipale L, Huumonen S, Soikkonen K, Norblad A. Prevalence of mucosal abnormalities of the maxillary sinus and their relationship to dental disease in panoramic radiography: results from the Health 2000 Health Examination Survey. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109(3):e80\u20137.","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"issue":"1","key":"1737_CR21","doi-asserted-by":"publisher","first-page":"23","DOI":"10.5051\/jpis.2011.41.1.23","volume":"41","author":"J Yoo","year":"2011","unstructured":"Yoo J, Pi S, Kim Y, Jeong S, You H. Healing pattern of the mucous membrane after tooth extraction in the maxillary sinus. J Period Implant Sci. 2011;41(1):23.","journal-title":"J Period Implant Sci"},{"issue":"1","key":"1737_CR22","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1111\/prd.12323","volume":"82","author":"PI Eke","year":"2000","unstructured":"Eke PI, Borgnakke WS, Genco RJ. Recent epidemiologic trends in periodontitis in the USA. Periodontol. 2000;82(1):257\u201367.","journal-title":"Periodontol"},{"key":"1737_CR23","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2015\/615486","volume":"2015","author":"SA Hienz","year":"2015","unstructured":"Hienz SA, Paliwal S, Ivanovski S. Mechanisms of bone resorption in periodontitis. J Immunol Res. 2015;2015:1\u201310.","journal-title":"J Immunol Res"},{"issue":"2","key":"1737_CR24","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1046\/j.0143-2885.2001.00524.x","volume":"35","author":"CHJ Hauman","year":"2002","unstructured":"Hauman CHJ, Chandler NP, Tong DC. Endodontic implications of the maxillary sinus: a review. Int Endod J. 2002;35(2):127\u201341.","journal-title":"Int Endod J"},{"issue":"6","key":"1737_CR25","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1902\/jop.1996.67.6.608","volume":"67","author":"I Brook","year":"1996","unstructured":"Brook I, Frazier EH, Gher ME. Microbiology of periapical abscesses and associated maxillary sinusitis. J Periodontol. 1996;67(6):608\u201310.","journal-title":"J Periodontol"}],"container-title":["BMC Oral Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12903-021-01737-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12903-021-01737-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12903-021-01737-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,6]],"date-time":"2023-01-06T22:59:50Z","timestamp":1673045990000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcoralhealth.biomedcentral.com\/articles\/10.1186\/s12903-021-01737-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,11]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["1737"],"URL":"https:\/\/doi.org\/10.1186\/s12903-021-01737-3","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-208842\/v1","asserted-by":"object"}]},"ISSN":["1472-6831"],"issn-type":[{"value":"1472-6831","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,11]]},"assertion":[{"value":"4 February 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 July 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 August 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Ethical approval was obtained from the Scientific Research Committee of Changsha Stomatological Hospital (CKY2020-0605). This clinical study was a retrospective study and only clinical data and imaging data of patients were collected. There was no intervention in the treatment plan of patients, no risk to the physiology of patients, no disclosure of personal privacy, and exemption from informed consent was approved by Ethics Committee of Scientific Research Department of Changsha Stomatological Hospital.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declares no conflict of interest related to this study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"392"}}