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Information on age, sex, location of the lesion, and the histopathologic diagnosis was analyzed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Over the course of twenty-one years, 1108 specimens were analyzed where reactive soft tissue lesions, which accounted for 397 (35.8%) of all cases ranked the highest presented category, followed by inflammatory odontogenic cysts, which accounted for 213 cases (19.2%). With 208 cases, the inflammatory radicular cyst was on the top of the most common 20 lesions, followed by pyogenic granuloma (160 cases). Malignancy was found in 19 cases, with soft tissue tumors (10 cases) being the most common, followed by salivary gland (5 cases) and bone pathologies (4 cases).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>The frequency of oral and maxillofacial pathological lesions among Egyptian children increased over the years but remained consistent with global trends.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Clinical relevance<\/jats:title>\n                <jats:p>This is the first study evaluating the relative frequency of oral and maxillofacial pathological lesions among Egyptian children and provides an insight into the most commonly encountered pediatric pathologies. This may aid in the understanding of the most prevalent oral lesions that impact the pediatric population, as well as providing the key to early detection of lesions.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12903-021-02037-6","type":"journal-article","created":{"date-parts":[[2022,1,7]],"date-time":"2022-01-07T08:03:09Z","timestamp":1641542589000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["A retrospective analysis of oral and maxillofacial pathological lesions in a group of Egyptian children over 21\u00a0years"],"prefix":"10.1186","volume":"22","author":[{"given":"Mariam Mohsen","family":"Aly","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manar Abdul-Waniss Mohammed","family":"Abdul-Aziz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marwa Aly","family":"Elchaghaby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,1,7]]},"reference":[{"issue":"1","key":"2037_CR1","doi-asserted-by":"publisher","first-page":"00189","DOI":"10.15406\/jdhodt.2017.06.00189","volume":"6","author":"S Ahmed","year":"2017","unstructured":"Ahmed S, Haider SM, Bokhari S. 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