{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T21:22:00Z","timestamp":1794345720869,"version":"4.9.0"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T00:00:00Z","timestamp":1691193600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T00:00:00Z","timestamp":1691193600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Oral Health"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>We present a case report on desquamative gingivitis diagnosed as linear IgA disease (LAD), which is a rare autoimmune bullous disease exclusively affecting the oral gingiva. The oral mucosa can be impacted by various autoimmune bullous diseases, and our report focuses on this particular manifestation of LAD.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>This patient presented with atypical symptoms, as frequent blister formation on the gingiva was the primary clinical manifestation. A combination of systemic and local treatment was administered to the patient. Following the treatment, there was a significant improvement observed in both the erythema and the bullous lesions on the gingiva.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>A more suitable local treatment strategy should be formulated for patients presenting with oral topical lesions, which clinicians can employ effectively.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12903-023-03250-1","type":"journal-article","created":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T05:01:50Z","timestamp":1691211710000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["An unusual case of linear IgA disease affecting only the oral gingiva: a case report"],"prefix":"10.1186","volume":"23","author":[{"given":"Jianing","family":"He","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4715-6120","authenticated-orcid":false,"given":"Jun","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,8,5]]},"reference":[{"issue":"4","key":"3250_CR1","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1111\/j.1834-7819.2003.tb00033.x","volume":"48","author":"NA Robinson","year":"2003","unstructured":"Robinson NA, Wray D. Desquamative gingivitis: a sign of mucocutaneous disorders\u2013a review. Aust Dent J. 2003;48(4):206\u201311.","journal-title":"Aust Dent J"},{"issue":"3","key":"3250_CR2","first-page":"184","volume":"9","author":"E Gagari","year":"2011","unstructured":"Gagari E, Damoulis PD. Desquamative gingivitis as a manifestation of chronic mucocutaneous disease. J Dtsch Dermatol Ges. 2011;9(3):184\u20138.","journal-title":"J Dtsch Dermatol Ges"},{"issue":"5","key":"3250_CR3","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1016\/j.jaad.2017.04.1140","volume":"78","author":"AD Maderal","year":"2018","unstructured":"Maderal AD, Lee SPR, Jorizzo JL. Desquamative gingivitis: diagnosis and treatment. J Am Acad Dermatol. 2018;78(5):851\u201361.","journal-title":"J Am Acad Dermatol"},{"issue":"2","key":"3250_CR4","doi-asserted-by":"publisher","first-page":"122","DOI":"10.4103\/0975-7406.129177","volume":"6","author":"S Hasan","year":"2014","unstructured":"Hasan S. Desquamative gingivitis - a clinical sign in mucous membrane pemphigoid: report of a case and review of literature. J Pharm Bioallied Sci. 2014;6(2):122\u20136.","journal-title":"J Pharm Bioallied Sci"},{"issue":"8","key":"3250_CR5","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1001\/jamadermatol.2021.0761","volume":"157","author":"T Hashimoto","year":"2021","unstructured":"Hashimoto T, Yamagami J, Zone JJ. History, diagnosis, pathogenesis, and nomenclature in sublamina densa-type linear IgA disease. JAMA Dermatol. 2021;157(8):907\u20139.","journal-title":"JAMA Dermatol"},{"issue":"6","key":"3250_CR6","first-page":"1093","volume":"21","author":"F Angiero","year":"2007","unstructured":"Angiero F, Benedicenti S, Crippa R, et al. A rare case of desquamative gingivitis due to linear IgA disease: morphological and immunofluorescence features. In Vivo. 2007;21(6):1093\u20138.","journal-title":"In Vivo"},{"issue":"2 Suppl 1","key":"3250_CR7","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1590\/abd1806-4841.2019940208","volume":"94","author":"E Vale","year":"2019","unstructured":"Vale E, Dimatos OC, Porro AM, et al. Consensus on the treatment of autoimmune bullous dermatoses: dermatitis herpetiformis and linear IgA bullous dermatosis - Brazilian Society of Dermatology. An Bras Dermatol. 2019;94(2 Suppl 1):48\u201355.","journal-title":"An Bras Dermatol"},{"issue":"4","key":"3250_CR8","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1080\/00016350152509256","volume":"59","author":"SJ Challacombe","year":"2001","unstructured":"Challacombe SJ, Setterfield J, Shirlaw P, et al. Immunodiagnosis of pemphigus and mucous membrane pemphigoid. Acta Odontol Scand. 2001;59(4):226\u201334.","journal-title":"Acta Odontol Scand"},{"issue":"2","key":"3250_CR9","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1684\/ejd.2019.3503","volume":"29","author":"T Matsumoto","year":"2019","unstructured":"Matsumoto T, Nakamura S, Ishii N, et al. Erythrodermic linear IgA\/IgG bullous dermatosis. Eur J Dermatol. 2019;29(2):220\u20131.","journal-title":"Eur J Dermatol"},{"issue":"5","key":"3250_CR10","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1111\/j.1365-2230.2007.02428.x","volume":"32","author":"A Lally","year":"2007","unstructured":"Lally A, Chamberlain A, Allen J, et al. Dermal-binding linear IgA disease: an uncommon subset of a rare immunobullous disease. Clin Exp Dermatol. 2007;32(5):493\u20138.","journal-title":"Clin Exp Dermatol"},{"issue":"8","key":"3250_CR11","doi-asserted-by":"publisher","first-page":"818","DOI":"10.3390\/medicina57080818","volume":"57","author":"L Shin","year":"2021","unstructured":"Shin L, Gardner JN, Dao HJ. Updates in the diagnosis and management of linear IgA disease: a systematic review. Medicina (Kaunas). 2021;57(8):818.","journal-title":"Medicina (Kaunas)"},{"issue":"2","key":"3250_CR12","first-page":"e136","volume":"24","author":"MJ Garcia-Pola","year":"2019","unstructured":"Garcia-Pola MJ, Rodriguez-Lopez S, Fernanz-Vigil A, et al. Oral hygiene instructions and professional control as part of the treatment of desquamative gingivitis. Systematic review. Med Oral Patol Oral Cir Bucal. 2019;24(2):e136-44.","journal-title":"Med Oral Patol Oral Cir Bucal"}],"container-title":["BMC Oral Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12903-023-03250-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12903-023-03250-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12903-023-03250-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T13:07:34Z","timestamp":1700226454000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcoralhealth.biomedcentral.com\/articles\/10.1186\/s12903-023-03250-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,5]]},"references-count":12,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,12]]}},"alternative-id":["3250"],"URL":"https:\/\/doi.org\/10.1186\/s12903-023-03250-1","relation":{},"ISSN":["1472-6831"],"issn-type":[{"value":"1472-6831","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,5]]},"assertion":[{"value":"17 October 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 July 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 August 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Informed consent about clinical management was obtained from the patient in this case. Written informed consent for publication of their details was obtained from the patient and was compliant with the hospital.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"A written informed consent for publication was obtained from the patient to publish all clinical date and any accompanying images and also a written consent to publish this information was obtained from study participant.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"All authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"541"}}