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All patients had OSA therapies around six months after confirm the\u00a0diagnosis\u00a0of\u00a0OSA. The tooth wear score and orofacial pain condition of all patients were recorded\u00a0via clinical examination. Cone beam computed tomography (CBCT) images were also taken when confirm the\u00a0diagnosis\u00a0of\u00a0OSA (<jats:italic>T<\/jats:italic><jats:sub><jats:italic>0<\/jats:italic><\/jats:sub>), 6\u00a0months after the diagnosis (<jats:italic>T<\/jats:italic><jats:sub><jats:italic>1<\/jats:italic><\/jats:sub>), and 6\u00a0months after the OSA treatment (<jats:italic>T<\/jats:italic><jats:sub><jats:italic>2<\/jats:italic><\/jats:sub>). Parameters indicating the condylar morphology and joint space were evaluated. The differences of clinical symptoms and TMJ conditions among<jats:italic>T<\/jats:italic><jats:sub><jats:italic>0<\/jats:italic><\/jats:sub><jats:italic>, T<\/jats:italic><jats:sub><jats:italic>1<\/jats:italic><\/jats:sub>and<jats:italic>T<\/jats:italic><jats:sub><jats:italic>2<\/jats:italic><\/jats:sub>time point were detected in the three groups respectively. The changes in<jats:italic>T<\/jats:italic><jats:sub><jats:italic>1<\/jats:italic><\/jats:sub><jats:italic>-T<\/jats:italic><jats:sub><jats:italic>0<\/jats:italic><\/jats:sub>and<jats:italic>T<\/jats:italic><jats:sub><jats:italic>2<\/jats:italic><\/jats:sub><jats:italic>-T<\/jats:italic><jats:sub><jats:italic>1<\/jats:italic><\/jats:sub>of all descriptions among three groups were also compared<jats:sub><jats:italic>.<\/jats:italic><\/jats:sub>The correlations between AHI and clinical symptoms were detected with Spearman correlation analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In mild group, there was no difference in all clinical symptoms and TMJ morphology among the three time points. Both in moderate and severe group, the condylar volume, superficial area, wear score, visual analogue scales (VAS), and R value (indicating condyle position) displayed significant differences among the three time points (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). From<jats:italic>T<\/jats:italic><jats:sub><jats:italic>0<\/jats:italic><\/jats:sub>to<jats:italic>T<\/jats:italic><jats:sub><jats:italic>1<\/jats:italic><\/jats:sub>, mild group displayed fewer decreases in the condylar volume and superficial area and fewer increases in wear score than that in moderate and severe group (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). From<jats:italic>T<\/jats:italic><jats:sub><jats:italic>1<\/jats:italic><\/jats:sub>to<jats:italic>T<\/jats:italic><jats:sub><jats:italic>2<\/jats:italic><\/jats:sub><jats:italic>,<\/jats:italic>there was a greatest reduction in severe group for R value, and significant difference in the description of VAS and R value were found among the three groups. AHI was negatively correlated condylar volume and condylar superficial area, and was positively correlated with tooth wear score and VAS (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Moderate to severe OSA will aggravate orofacial pain and tooth wear, affect TMJ volume and superficial area, even change the location of condyles. Appropriate OSA therapies may be effective ways to alleviate these adverse effects in long-term.<\/jats:p><\/jats:sec>","DOI":"10.1186\/s12903-023-03264-9","type":"journal-article","created":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T12:01:29Z","timestamp":1692446489000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Obstructive sleep apnea: a follow-up program in its relation to temporomandibular joint disorder, sleep bruxism and orofacial pain"],"prefix":"10.1186","volume":"23","author":[{"given":"Ruoyu","family":"Ning","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junjie","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanqin","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,8,19]]},"reference":[{"key":"3264_CR1","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.smrv.2016.07.002","volume":"34","author":"CV Senaratna","year":"2017","unstructured":"Senaratna CV, Perret JL, Lodge CJ, Lowe AJ, Campbell BE, Matheson MC, et al. 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