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First, rheological properties of commercial and modified adhesives were evaluated. The effect of remineralization\/hardness and microtensile bond-strength (MTBs) of those samples that mimicked the rheological properties of commercial adhesives were evaluated using Vickers hardness tester and universal testing machine respectively. Scanning-Electron microscope was used to visualize failed samples of MTBs and remineralization samples. Both evaluations were carried out at 1-,3 and 6-month intervals, samples being stored in stimulated salivary fluid during each time interval.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Addition of nanoparticles altered the rheological properties. With increase in the weight percentage of nanoparticles in commercial adhesive, there was significant increase in degree of conversion, viscosity and sedimentation rate (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). The 0.2 and 0.5 wgt% groups closely mimicked the properties of commercial adhesive and were evaluated for remineralization and MTBs. After 6\u00a0months, 0.2wgt% group showed increased MTBs (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05) and 0.5wgt% group increased remineralization\/hardness (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The complex of PAMAM-MBG-Universal adhesive can remineralize the demineralised CAD thereby improving its bond-strength when evaluated for up to 6-months.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12903-023-03536-4","type":"journal-article","created":{"date-parts":[[2023,10,28]],"date-time":"2023-10-28T07:02:37Z","timestamp":1698476557000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Evaluating the effect of poly (amidoamine) treated bioactive glass nanoparticle incorporated in universal adhesive on bonding to artificially induced caries affected dentin"],"prefix":"10.1186","volume":"23","author":[{"given":"Akhil C.","family":"Rao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vijay Venkatesh","family":"Kondas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vidyashree","family":"Nandini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravi","family":"Kirana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pradeep Kumar","family":"Yadalam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajalakshmanan","family":"Eswaramoorthy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,10,28]]},"reference":[{"issue":"1","key":"3536_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.11138\/ads\/2017.8.1.001","volume":"8","author":"E Sofan","year":"2017","unstructured":"Sofan E, Sofan A, Palaia G, Tenore G, Romeo U, Migliau G. 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The need for written informed consent was waived by the research committee of institutional ethics committee, SRM Medical College hospital and Research Centre, Chennai, as this study was an in vitro model study. All the experimental protocols were approved by the proceeding of institutional ethics committee, SRM Medical College hospital and Research Centre with ethics clearance number 1797\/IEC\/2019.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"810"}}