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Group A1, B1: Excavation was performed using diamond points. Group A2, B2: CDD (Sable Seek\u2122 caries indicator, Ultradent) was applied and left for 10\u00a0s, and then the cavity was rinsed and dried. For caries removal, diamond points or excavators were used. Group A3 and B3: BRIX3000 papain gel was applied with a micro-brush for 20\u00a0s and was activated for 2\u00a0min, and then the carious tissue was removed with a sharp spoon excavator. Post-excavation cavity volume analysis was performed using a 3D scanner. The time required and the verbal pain score (VPS) for pain were scored during excavation. Post-restoration evaluation was performed at 1, 3, and 6 months FDI (Federation Dentaire Internationale) criteria.\n<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Comparison of age, time and volume with study groups were made using Independent Sample\u2019 t\u2019 test and one-way analysis of variance (ANOVA) for two and more than two groups, respectively. Using Cohen\u2019s Kappa Statistics, evaluators 1 and 2 agreed on caries removal status aesthetic, functional and biological properties at different follow-ups. The chi-square test revealed that the rotary groups [A1(2.5\u2009\u00b1\u20090.4\u00a0min) B1(4.0\u2009\u00b1\u20090.4\u00a0min)] had significantly less (<jats:italic>p<\/jats:italic>\u2009=\u20090.000) mean procedural time than CDD [A2(4.5\u2009\u00b1\u20090.4\u00a0min) B2(5.7\u2009\u00b1\u20090.4\u00a0min)] and CMCR [A3(5.4\u2009\u00b1\u20090.7\u00a0min) B3(6.2\u2009\u00b1\u20090.6\u00a0min)] groups. The CMCR group showed better patient acceptance and less pain during caries excavation than the rotary and CDD groups. CMCR group showed significantly less mean caries excavated volume(<jats:italic>p<\/jats:italic>\u2009=\u20090.000). Evaluation of restoration after 1-, 3-, and 6-month intervals was acceptable for all the groups.\n<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Brix3000 helps effectively remove denatured teeth with less pain or sensitivity. The time required for caries removal was lowest in the rotary method and highest in the brix3000 group, while the volume of caries removed was the lowest for brix3000 and highest for the rotary group.\n<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12903-024-03907-5","type":"journal-article","created":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T16:02:53Z","timestamp":1706803373000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Volumetric analysis after caries excavation with caries detecting dyes and chemomechanical caries removal agents using 3D scanner-a randomised clinical trial"],"prefix":"10.1186","volume":"24","author":[{"given":"Roja","family":"Bastia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shashirekha","family":"Govind","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali A.","family":"Assiry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noura Abdulaziz","family":"Alessa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Abdul","family":"Kader","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adbul Habeeb","family":"Adil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohmed Isaqali","family":"Karobari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,2,1]]},"reference":[{"key":"3907_CR1","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1177\/10454411000110040601","volume":"11","author":"C Robinson","year":"2000","unstructured":"Robinson C, Shore R, Brookes SJ, Strafford S, Wood S, Kirkham J. 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