{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T12:46:40Z","timestamp":1793278000935,"version":"4.5.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T00:00:00Z","timestamp":1708387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T00:00:00Z","timestamp":1708387200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Oral Health"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Desmoplastic fibroma (DF) is an uncommon bone tumor that originates from the mesenchymal tissue and despite being benign, exhibits aggressive behavior locally. The following report describes the case of a 7-year-old boy with a rapidly enlarging swelling on the right side of the mandible. After a thorough clinical examination, radiographic imaging, and histopathological analysis, the diagnosis of DF was confirmed. Treatment planning was formulated considering both the tumor\u2019s tendency for local recurrence and the patient\u2019s well-being. Due to the patient\u2019s young age, segmental resection was not deemed appropriate, and an aggressive curettage and enucleation of the lesion followed by the bone graft was performed instead. The patient was kept under close follow-up for the first month of post-surgery and later reviewed after 3, 6, 9, and 12 months, respectively. Good bone healing was observed on radiographs. The patient did not show any signs of recurrence based on clinical or radiographic assessments and did not exhibit any neurosensory deficits as well.<\/jats:p>","DOI":"10.1186\/s12903-024-04018-x","type":"journal-article","created":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T08:02:34Z","timestamp":1708416154000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Unraveling the challenges in the diagnosis and management of desmoplastic fibroma of the mandible\u2013a case report"],"prefix":"10.1186","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7542-4807","authenticated-orcid":false,"given":"Humayun Kaleem","family":"Siddiqui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6002-9946","authenticated-orcid":false,"given":"Shahrukh Ali","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7519-4944","authenticated-orcid":false,"given":"Anum","family":"Aijaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8705-4727","authenticated-orcid":false,"given":"Madiha Bilal","family":"Qureshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,2,20]]},"reference":[{"key":"4018_CR1","first-page":"367","volume":"1","author":"R Langlais","year":"1995","unstructured":"Langlais R, Langland O, Nortje C. Multilocular radiolucencies. Diagn Imaging jaws. 1995;1:367\u201370.","journal-title":"Diagn Imaging jaws"},{"issue":"4","key":"4018_CR2","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1016\/0007-1226(84)90129-2","volume":"37","author":"SJ Siemssen","year":"1984","unstructured":"Siemssen SJ, Anagnostaki T. Aggressive fibromatosis (extra-abdominal desmoids) of the head and neck. Br J Plast Surg. 1984;37(4):453\u20137.","journal-title":"Br J Plast Surg"},{"issue":"1","key":"4018_CR3","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.tripleo.2005.03.034","volume":"101","author":"N Said-Al-Naief","year":"2006","unstructured":"Said-Al-Naief N, Fernandes R, Louis P, Bell W, Siegal GP. Desmoplastic fibroma of the jaw: a case report and review of literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;101(1):82\u201394.","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"4018_CR4","doi-asserted-by":"crossref","unstructured":"Jaffe H. Tumors and tumorous con-ditions of the bones and joints. Phila Lea. 1958.","DOI":"10.1097\/00001888-195901000-00023"},{"issue":"2","key":"4018_CR5","first-page":"450","volume":"4","author":"N Anand","year":"2015","unstructured":"Anand N, Kanmani R, Anandi M, Krithika C, Kannan A, Raghuram P. Desmoplastic fibroma of ramus of mandible\u2013a rare case report. Int J Med Res Health Sci. 2015;4(2):450\u20133.","journal-title":"Int J Med Res Health Sci"},{"issue":"52","key":"4018_CR6","doi-asserted-by":"publisher","first-page":"e13787","DOI":"10.1097\/MD.0000000000013787","volume":"97","author":"Y Xu","year":"2018","unstructured":"Xu Y, Wang Y, Yan J, Bai X, Xing G. Desmoplastic fibroma of the femur with atypical image findings: a case report. Medicine. 2018;97(52):e13787.","journal-title":"Medicine"},{"key":"4018_CR7","first-page":"35","volume":"4","author":"C Fletcher","year":"2002","unstructured":"Fletcher C. Pathology and genetics of tumors of soft tissue and bone. World Health Organ Classif Tumors. 2002;4:35\u201346.","journal-title":"World Health Organ Classif Tumors"},{"key":"4018_CR8","unstructured":"J. : M. \u00dcber den feineren bau und die Formen Der Krankhaften Geschw\u00fclste. Erste Lieferung Berlin: G Reimer;. 1838."},{"key":"4018_CR9","doi-asserted-by":"crossref","unstructured":"Griffith JG, Irby WB. DESMOPLASTIC, FIBROMA. REPORT OF A RARE TUMOR OF THE ORAL STRUCTURES. Oral Surg Oral Med Oral Pathol. 1965;20:269\u201375.","DOI":"10.1016\/0030-4220(65)90201-X"},{"key":"4018_CR10","unstructured":"Badger GA, Syed AA, Malby FC. Desmoplastic fibroma of the mandible. Can J Otolaryngol. 1974;3(4):605\u201310."},{"issue":"2","key":"4018_CR11","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1046\/j.1365-263x.1999.00115.x","volume":"9","author":"G Bakaeen","year":"1999","unstructured":"Bakaeen G, Rajab LD. Desmoplastic fibroma of the mandible: report of a case. Int J Pediatr Dent. 1999;9(2):117\u201321.","journal-title":"Int J Pediatr Dent"},{"issue":"4","key":"4018_CR12","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1016\/S0301-0503(76)80045-8","volume":"4","author":"L Calatrava","year":"1976","unstructured":"Calatrava L, Donado M. Desmoplastic fibroma of the mandible: case report. J Maxillofac Surg. 1976;4(4):238\u201341.","journal-title":"J Maxillofac Surg"},{"issue":"2","key":"4018_CR13","first-page":"47","volume":"36","author":"TL Green","year":"1981","unstructured":"Green TL, Gaffney E. Desmoplastic fibroma of the mandible. J oral Med. 1981;36(2):47\u20139.","journal-title":"J oral Med"},{"issue":"9","key":"4018_CR14","doi-asserted-by":"publisher","first-page":"1078","DOI":"10.1053\/joms.2001.25032","volume":"59","author":"AS Herford","year":"2001","unstructured":"Herford AS, Reder P, Ducic Y. Multifocal desmoplastic fibromas of the mandible. J oral Maxillofacial Surgery: Official J Am Association Oral Maxillofacial Surg. 2001;59(9):1078\u201381.","journal-title":"J oral Maxillofacial Surgery: Official J Am Association Oral Maxillofacial Surg"},{"issue":"2","key":"4018_CR15","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1097\/SAP.0b013e31817f020d","volume":"62","author":"H Sinno","year":"2009","unstructured":"Sinno H, Zadeh T. Desmoid tumors of the pediatric mandible: case report and review. Ann Plast Surg. 2009;62(2):213\u20139.","journal-title":"Ann Plast Surg"},{"issue":"10","key":"4018_CR16","first-page":"793","volume":"57","author":"NM Triantafyllou","year":"1972","unstructured":"Triantafyllou NM, Triantafyllou DN, Antonados DN. Desmoid tumors of the bone. Int Surg. 1972;57(10):793\u20137.","journal-title":"Int Surg"},{"issue":"3","key":"4018_CR17","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1016\/S0002-9440(10)65319-9","volume":"154","author":"JA Bridge","year":"1999","unstructured":"Bridge JA, Swarts SJ, Buresh C, Nelson M, Degenhardt JM, Spanier S, et al. Trisomies 8 and 20 characterize a subgroup of benign fibrous lesions arising in both soft tissue and bone. Am J Pathol. 1999;154(3):729\u201333.","journal-title":"Am J Pathol"},{"issue":"3","key":"4018_CR18","doi-asserted-by":"publisher","first-page":"149","DOI":"10.2334\/josnusd.47.149","volume":"47","author":"A Ikeshima","year":"2005","unstructured":"Ikeshima A, Utsunomiya T. Case report of intra-osseous fibroma: a study on odontogenic and desmoplastic fibromas with a review of the literature. J Oral Sci. 2005;47(3):149\u201357.","journal-title":"J Oral Sci"},{"issue":"6","key":"4018_CR19","doi-asserted-by":"publisher","first-page":"1247","DOI":"10.2214\/ajr.148.6.1247","volume":"148","author":"M Sundaram","year":"1987","unstructured":"Sundaram M, McGuire MH, Schajowicz F. Soft-tissue masses: histologic basis for decreased signal (short T2) on T2-weighted MR images. AJR Am J Roentgenol. 1987;148(6):1247\u201350.","journal-title":"AJR Am J Roentgenol"},{"issue":"3\u20134","key":"4018_CR20","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.jbo.2014.08.001","volume":"3","author":"S Evans","year":"2014","unstructured":"Evans S, Ramasamy A, Jeys L, Grimer R. Desmoplastic fibroma of bone: a rare bone tumour. J bone Oncol. 2014;3(3\u20134):77\u20139.","journal-title":"J bone Oncol"},{"key":"4018_CR21","doi-asserted-by":"crossref","unstructured":"Slootweg PJ, M\u00fcller H. Central fibroma of the jaw, odontogenic or desmoplastic. Oral Surg Oral Med Oral Pathol. 1983;56(1):61\u201370.","DOI":"10.1016\/0030-4220(83)90057-9"},{"key":"4018_CR22","unstructured":"Regezi J, Sciubba J. Odontogenic tumors, benign nonodontogenic tumors. Oral pathology: clinical pathologic correlations. 1999;3."},{"key":"4018_CR23","doi-asserted-by":"crossref","unstructured":"Depprich R, Handschel J, Sebald W, K\u00fcbler NR, W\u00fcrzler KK. Comparison of the osteogenic activity of bone morphogenetic protein (BMP) mutants. Mund- Kiefer- und Gesichtschirurgie: MKG. 2005;9(6):363\u20138.","DOI":"10.1007\/s10006-005-0644-2"},{"key":"4018_CR24","doi-asserted-by":"crossref","unstructured":"Guruprasad Y, Chauhan DS. Desmoplastic fibroma of mandible. Med J Dr DY Patil Univ. 2015;8(2):254.","DOI":"10.4103\/0975-2870.153180"},{"issue":"1","key":"4018_CR25","doi-asserted-by":"publisher","first-page":"74","DOI":"10.4103\/jiaomr.jiaomr_213_18","volume":"31","author":"S Konikoth","year":"2019","unstructured":"Konikoth S, Bose T, Anupama IV, Yogidas R. Desmoplastic fibroma of the mandible \u2013 a rare benign tumor mimicking malignancy. J Indian Acad Oral Med Radiol. 2019;31(1):74\u20138.","journal-title":"J Indian Acad Oral Med Radiol"},{"issue":"2","key":"4018_CR26","doi-asserted-by":"publisher","first-page":"1506","DOI":"10.3892\/ol.2015.4058","volume":"11","author":"J Rui","year":"2016","unstructured":"Rui J, Guan W, Gu Y, Lao J. Treatment and functional result of desmoplastic fibroma with repeated recurrences in the forearm: a case report. Oncol Lett. 2016;11(2):1506\u20138.","journal-title":"Oncol Lett"},{"issue":"2","key":"4018_CR27","doi-asserted-by":"publisher","first-page":"215","DOI":"10.3109\/17453678408992340","volume":"55","author":"N Graudal","year":"1984","unstructured":"Graudal N. Desmoplastic fibroma of bone. Case report and literature review. Acta Orthop Scand. 1984;55(2):215\u20139.","journal-title":"Acta Orthop Scand"},{"issue":"3","key":"4018_CR28","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1148\/radiology.172.3.2772196","volume":"172","author":"JR Crim","year":"1989","unstructured":"Crim JR, Gold RH, Mirra JM, Eckardt JJ, Bassett LW. Desmoplastic fibroma of bone: radiographic analysis. Radiology. 1989;172(3):827\u201332.","journal-title":"Radiology"},{"issue":"4","key":"4018_CR29","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1007\/BF02412362","volume":"23","author":"WK Taconis","year":"1994","unstructured":"Taconis WK, Sch\u00fctte HE, van der Heul RO. Desmoplastic fibroma of bone: a report of 18 cases. Skeletal Radiol. 1994;23(4):283\u20138.","journal-title":"Skeletal Radiol"},{"issue":"10","key":"4018_CR30","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.1016\/S0278-2391(96)90363-8","volume":"54","author":"KM Hopkins","year":"1996","unstructured":"Hopkins KM, Huttula CS, Kahn MA, Albright JE. Desmoplastic fibroma of the mandible: review and report of two cases. J oral Maxillofacial Surgery: Official J Am Association Oral Maxillofacial Surg. 1996;54(10):1249\u201354.","journal-title":"J oral Maxillofacial Surgery: Official J Am Association Oral Maxillofacial Surg"},{"issue":"3","key":"4018_CR31","doi-asserted-by":"publisher","first-page":"982","DOI":"10.1097\/SCS.0b013e3182101400","volume":"22","author":"P Boffano","year":"2011","unstructured":"Boffano P, Gallesio C, Barreca A, Bianchi FA, Garzino-Demo P, Roccia F. Surgical treatment of odontogenic myxoma. J Craniofac Surg. 2011;22(3):982\u20137.","journal-title":"J Craniofac Surg"},{"issue":"12","key":"4018_CR32","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1016\/j.jcms.2021.09.007","volume":"49","author":"P Boffano","year":"2021","unstructured":"Boffano P, Cavarra F, Tricarico G, Masu L, Brucoli M, Ruslin M, et al. The epidemiology and management of ameloblastomas: a European multicenter study. J Craniomaxillofac Surg. 2021;49(12):1107\u201312.","journal-title":"J Craniomaxillofac Surg"},{"issue":"1","key":"4018_CR33","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.jormas.2021.01.014","volume":"123","author":"J Richardson","year":"2022","unstructured":"Richardson J, Litman E, Stanbouly D, Lee KC, Philipone E. Aneurysmal bone cyst of the head & neck: a review of reported cases in the literature. J Stomatol Oral Maxillofac Surg. 2022;123(1):59\u201363.","journal-title":"J Stomatol Oral Maxillofac Surg"},{"key":"4018_CR34","unstructured":"Lyssy LA, Puckett Y, Oral H. 2023 Aug 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan\u2013. PMID: 32809603. Copyright \u00a9 2024, StatPearls Publishing LLC.; 2024."},{"key":"4018_CR35","unstructured":"Shaw SE, Chan CH. Non-odontogenic tumors of the Jaws. 2023 Jul 25. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan\u2013. PMID: 35015466. Copyright \u00a9 2024. StatPearls Publishing LLC.; 2024."},{"issue":"2","key":"4018_CR36","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1007\/s12105-014-0561-5","volume":"9","author":"TR Woods","year":"2015","unstructured":"Woods TR, Cohen DM, Islam MN, Rawal Y, Bhattacharyya I. Desmoplastic fibroma of the mandible: a series of three cases and review of literature. Head Neck Pathol. 2015;9(2):196\u2013204.","journal-title":"Head Neck Pathol"},{"issue":"5","key":"4018_CR37","doi-asserted-by":"publisher","first-page":"1011","DOI":"10.1002\/(SICI)1097-0142(19960901)78:5<1011::AID-CNCR11>3.0.CO;2-5","volume":"78","author":"P B\u00f6hm","year":"1996","unstructured":"B\u00f6hm P, Kr\u00f6ber S, Greschniok A, Laniado M, Kaiserling E. Desmoplastic fibroma of the bone. A report of two patients, review of the literature, and therapeutic implications. Cancer. 1996;78(5):1011\u201323.","journal-title":"Cancer"},{"key":"4018_CR38","doi-asserted-by":"publisher","first-page":"40","DOI":"10.2174\/1874325001307010040","volume":"8","author":"A Nedopil","year":"2013","unstructured":"Nedopil A, Raab P, Rudert M. Desmoplastic fibroma: a case report with three years of clinical and radiographic observation and review of the literature. open Orthop J. 2013;8:40\u20136.","journal-title":"open Orthop J"},{"issue":"3","key":"4018_CR39","first-page":"e25518","volume":"12","author":"Y Safi","year":"2015","unstructured":"Safi Y, Shamloo N, Heidar H, Valizadeh S, Aghdasi MM, Eslami Manouchehri M, Desmoplastic, Fibroma. Report of a rare case in Infraorbital Rim. Iran J Radiology: Q J Published Iran Radiological Soc. 2015;12(3):e25518.","journal-title":"Iran J Radiology: Q J Published Iran Radiological Soc"},{"issue":"9","key":"4018_CR40","doi-asserted-by":"publisher","first-page":"1978","DOI":"10.1002\/1097-0142(19911101)68:9<1978::AID-CNCR2820680922>3.0.CO;2-H","volume":"68","author":"CY Inwards","year":"1991","unstructured":"Inwards CY, Unni KK, Beabout JW, Sim FH. Desmoplastic fibroma of bone. Cancer. 1991;68(9):1978\u201383.","journal-title":"Cancer"},{"issue":"2","key":"4018_CR41","first-page":"138","volume":"3","author":"AG Ayala","year":"1986","unstructured":"Ayala AG, Ro JY, Goepfert H, Cangir A, Khorsand J, Flake G. Desmoid fibromatosis: a clinicopathologic study of 25 children. Semin Diagn Pathol. 1986;3(2):138\u201350.","journal-title":"Semin Diagn Pathol"},{"issue":"11","key":"4018_CR42","doi-asserted-by":"publisher","first-page":"1370","DOI":"10.1016\/S0278-2391(96)90500-5","volume":"54","author":"S Iwai","year":"1996","unstructured":"Iwai S, Matsumoto K, Sakuda M. Desmoplastic fibroma of the mandible mimicking osteogenic sarcoma: report of a case. J oral Maxillofacial Surgery: Official J Am Association Oral Maxillofacial Surg. 1996;54(11):1370\u20133.","journal-title":"J oral Maxillofacial Surgery: Official J Am Association Oral Maxillofacial Surg"}],"container-title":["BMC Oral Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12903-024-04018-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12903-024-04018-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12903-024-04018-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T08:03:19Z","timestamp":1708416199000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcoralhealth.biomedcentral.com\/articles\/10.1186\/s12903-024-04018-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,20]]},"references-count":42,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["4018"],"URL":"https:\/\/doi.org\/10.1186\/s12903-024-04018-x","relation":{},"ISSN":["1472-6831"],"issn-type":[{"value":"1472-6831","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,20]]},"assertion":[{"value":"17 August 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 February 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 February 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient\u2019s father for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"256"}}