{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T13:45:09Z","timestamp":1784555109159,"version":"3.55.0"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,7,13]],"date-time":"2024-07-13T00:00:00Z","timestamp":1720828800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,7,13]],"date-time":"2024-07-13T00:00:00Z","timestamp":1720828800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100019652","name":"British University in Egypt","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100019652","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Oral Health"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>This study aimed to assess the quality of various obturation techniques to fill perforation caused by internal root resorption using Micro-computed Tomography.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Cone-beam computed tomography images of a maxillary central incisor tooth with perforating internal resorptive defect were used to create a 3D printed model of the affected tooth. The replicas were divided into four groups based on the obturation technique used. The techniques included Group 1: a polydimethylsiloxane-based sealer (GuttaFlow-2) with gutta-percha. Group 2: same as Group 1 except for using a pre-mixed Bioceramic-based sealer (NeoSEALER Flo). Group 3: the defect was filled entirely using the NeoSealer Flo Bioceramic-based sealer. Group 4: the samples were obturated using the warm vertical compaction technique with a resin-based sealer (ADSeal). The resin models were then scanned a micro-computed scanner to evaluate the percentage of voids in each group.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The results showed that NeoSEALER Flo groups had significantly the highest volume of voids while GuttaFlow-2 and warm vertical compaction groups had the lowest void volume.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>GuttaFlow-2 and warm vertical compaction techniques performed best in filling the internal resorptive defect.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12903-024-04518-w","type":"journal-article","created":{"date-parts":[[2024,7,13]],"date-time":"2024-07-13T01:01:39Z","timestamp":1720832499000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Quality of different obturation techniques to fill perforating internal root resorption: a micro-computed tomographic study"],"prefix":"10.1186","volume":"24","author":[{"given":"Shaimaa Mohamed Abu El","family":"Sadat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hooi Pin","family":"Chew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Fok","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Mohamed","family":"Elashiry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed M.","family":"ElShenawy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shehabeldin","family":"Saber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,7,13]]},"reference":[{"key":"4518_CR1","doi-asserted-by":"publisher","first-page":"4","DOI":"10.4103\/0972-0707.105290","volume":"16","author":"M Fernandes","year":"2013","unstructured":"Fernandes M, de Ataide I, Wagle R. Tooth resorption part I - pathogenesis and case series of internal resorption. J Conserv Dent. 2013;16:4\u20138.","journal-title":"J Conserv Dent"},{"key":"4518_CR2","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1016\/j.joen.2010.03.014","volume":"36","author":"S Patel","year":"2010","unstructured":"Patel S, Ricucci D, Durak C, Tay F. Internal root resorption: a review. J Endod. 2010;36:1107\u201321.","journal-title":"J Endod"},{"key":"4518_CR3","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1111\/j.1747-4477.2009.00197.x","volume":"36","author":"G Rossi-Fedele","year":"2010","unstructured":"Rossi-Fedele G, Figueiredo JA, Abbott PV. Teeth with double internal inflammatory resorption: report of two cases. Aust Endod J. 2010;36:122\u20139.","journal-title":"Aust Endod J"},{"key":"4518_CR4","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1016\/j.joen.2005.10.001","volume":"32","author":"J Collins","year":"2006","unstructured":"Collins J, Walker MP, Kulild J, Lee C. A comparison of three gutta-percha obturation techniques to replicate canal irregularities. J Endod. 2006;32:762\u20135.","journal-title":"J Endod"},{"key":"4518_CR5","doi-asserted-by":"publisher","first-page":"e28","DOI":"10.1016\/j.tripleo.2006.06.007","volume":"103","author":"J Kulild","year":"2007","unstructured":"Kulild J, Lee C, Dryden J, Collins J, Feil P. A comparison of 5 gutta-percha obturation techniques to replicate canal defects. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;103:e28\u201332.","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"4518_CR6","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1111\/j.1600-9657.1987.tb00167.x","volume":"3","author":"FM Andreasen","year":"1987","unstructured":"Andreasen FM, Sewerin I, Mandel U, Andreasen JO. Radiographic assessment of simulated root resorption cavities. Endod Dent Traumatol. 1987;3:21\u20137.","journal-title":"Endod Dent Traumatol"},{"key":"4518_CR7","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1034\/j.1600-9657.2000.016003116.x","volume":"16","author":"F Goldberg","year":"2000","unstructured":"Goldberg F, Massone EJ, Esmoris M, Alfie D. Comparison of different techniques for obturating experimental internal resorptive cavities. Endod Dent Traumatol. 2000;16:116\u201321.","journal-title":"Endod Dent Traumatol"},{"key":"4518_CR8","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1111\/j.1600-9657.1997.tb00014.x","volume":"13","author":"MK Caliskan","year":"1997","unstructured":"Caliskan MK, Turkun M. Prognosis of permanent teeth with internal resorption: a clinical review. Endod Dent Traumatol. 1997;13:75\u201381.","journal-title":"Endod Dent Traumatol"},{"key":"4518_CR9","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1016\/S0099-2399(87)80112-7","volume":"13","author":"RL Skinner","year":"1987","unstructured":"Skinner RL, Himel VT. The sealing ability of injection-molded thermoplasticized gutta-percha with and without the use of sealers. J Endod. 1987;13:315\u20137.","journal-title":"J Endod"},{"key":"4518_CR10","doi-asserted-by":"publisher","first-page":"6757","DOI":"10.1007\/s00784-023-05288-5","volume":"27","author":"SM Saber","year":"2023","unstructured":"Saber SM, Gomaa SM, Elashiry MM, El-Banna A, Schafer E. Comparative biological properties of resin-free and resin-based calcium silicate-based endodontic repair materials on human periodontal ligament stem cells. Clin Oral Investig. 2023;27:6757\u201368.","journal-title":"Clin Oral Investig"},{"key":"4518_CR11","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1111\/iej.12843","volume":"51","author":"M Torabinejad","year":"2018","unstructured":"Torabinejad M, Parirokh M, Dummer PMH. Mineral trioxide aggregate and other bioactive endodontic cements: an updated overview - part II: other clinical applications and complications. Int Endod J. 2018;51:284\u2013317.","journal-title":"Int Endod J"},{"key":"4518_CR12","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1016\/j.sdentj.2019.11.005","volume":"32","author":"M Shalabi","year":"2020","unstructured":"Shalabi M, Saber S, Elsewify T. Influence of blood contamination on the bond strength and biointeractivity of Biodentine used as root-end filling. Saudi Dent J. 2020;32:373\u201381.","journal-title":"Saudi Dent J"},{"key":"4518_CR13","doi-asserted-by":"crossref","unstructured":"Drukteinis S, Camilleri J. Bioceramic materials in clinical endodontics. Springer; 2021.","DOI":"10.1007\/978-3-030-58170-1"},{"key":"4518_CR14","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1016\/j.joen.2009.03.006","volume":"35","author":"G Bogen","year":"2009","unstructured":"Bogen G, Kuttler S. Mineral trioxide aggregate obturation: a review and case series. J Endod. 2009;35:777\u201390.","journal-title":"J Endod"},{"key":"4518_CR15","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/j.joen.2023.10.014","volume":"50","author":"AJS Torres-Carrillo","year":"2024","unstructured":"Torres-Carrillo AJS, Assis HC, Salazar-Gamarra RE, et al. Evaluation of different techniques and materials for filling in 3-dimensional printed teeth replicas with perforating internal resorption by means of micro-computed tomography. J Endod. 2024;50:205\u201312.","journal-title":"J Endod"},{"key":"4518_CR16","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/j.joen.2013.07.007","volume":"40","author":"PF da Silveira","year":"2014","unstructured":"da Silveira PF, Vizzotto MB, Montagner F, da Silveira HL, da Silveira HE. Development of a new in vitro methodology to simulate internal root resorption. J Endod. 2014;40:211\u20136.","journal-title":"J Endod"},{"key":"4518_CR17","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/j.joen.2010.11.002","volume":"37","author":"K Kamburoglu","year":"2011","unstructured":"Kamburoglu K, Kursun S, Yuksel S, Oztas B. Observer ability to detect ex vivo simulated internal or external cervical root resorption. J Endod. 2011;37:168\u201375.","journal-title":"J Endod"},{"key":"4518_CR18","first-page":"21","volume":"4","author":"KA Yazdi","year":"2019","unstructured":"Yazdi KA, Aminsobhani M, Alemi P. Comparing the ability of different materials and techniques in filling artificial internal resorption cavities. Eur Endod J. 2019;4:21\u20137.","journal-title":"Eur Endod J"},{"issue":"Suppl 2","key":"4518_CR19","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1111\/iej.13713","volume":"55","author":"G De-Deus","year":"2022","unstructured":"De-Deus G, Souza EM, Silva E, et al. A critical analysis of research methods and experimental models to study root canal fillings. Int Endod J. 2022;55(Suppl 2):384\u2013445.","journal-title":"Int Endod J"},{"key":"4518_CR20","doi-asserted-by":"publisher","first-page":"128","DOI":"10.4103\/0970-7212.352341","volume":"26","author":"R Basavanna","year":"2014","unstructured":"Basavanna R, Dhanya Kumar N, Pendharkar K. Effectiveness of four different gutta percha techniques in filling experimental internal resorptive lesions - an in vitro study. Endodontology. 2014;26:128\u201336.","journal-title":"Endodontology"},{"key":"4518_CR21","doi-asserted-by":"publisher","first-page":"14829","DOI":"10.1038\/s41598-023-41798-8","volume":"13","author":"S Saber","year":"2023","unstructured":"Saber S, Galal MM, Ismail AG, Hamdy TM. Thermal, chemical and physical analysis of VDW.1Seal, fill Root ST, and ADseal root canal sealers. Sci Rep. 2023;13:14829.","journal-title":"Sci Rep"},{"key":"4518_CR22","doi-asserted-by":"publisher","first-page":"2344","DOI":"10.3390\/jcm12062344","volume":"12","author":"S Saber","year":"2023","unstructured":"Saber S, Raafat S, Elashiry M, El-Banna A, Sch\u00e4fer E. Effect of different sealers on the cytocompatibility and osteogenic potential of human periodontal ligament stem cells: an in vitro study. J Clin Med. 2023;12:2344.","journal-title":"J Clin Med"},{"key":"4518_CR23","doi-asserted-by":"publisher","first-page":"8985","DOI":"10.1038\/s41598-023-36005-7","volume":"13","author":"SM Saber","year":"2023","unstructured":"Saber SM, Elashiry MM, Sadat S, Nawar NN. A microcomputed tomographic analysis of the morphological variabilities and incidence of extra canals in mandibular first molar teeth in an Egyptian subpopulation. Sci Rep. 2023;13:8985.","journal-title":"Sci Rep"},{"key":"4518_CR24","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1111\/j.1365-2591.2007.01323.x","volume":"41","author":"YL Ng","year":"2008","unstructured":"Ng YL, Mann V, Rahbaran S, Lewsey J, Gulabivala K. Outcome of primary root canal treatment: systematic review of the literature -- part 2. Influence of clinical factors. Int Endod J. 2008;41:6\u201331.","journal-title":"Int Endod J"},{"key":"4518_CR25","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1016\/j.joen.2006.02.007","volume":"32","author":"H Schilder","year":"2006","unstructured":"Schilder H. Filling root canals in three dimensions. 1967. J Endod. 2006;32:281\u201390.","journal-title":"J Endod"},{"key":"4518_CR26","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1046\/j.1365-2591.1997.00109.x","volume":"30","author":"AS McRobert","year":"1997","unstructured":"McRobert AS, Lumley PJ. An in vitro investigation of coronal leakage with three gutta-percha backfilling techniques. Int Endod J. 1997;30:413\u20137.","journal-title":"Int Endod J"},{"key":"4518_CR27","doi-asserted-by":"publisher","first-page":"e0224793","DOI":"10.1371\/journal.pone.0224793","volume":"14","author":"A\u00d6 Karatekin","year":"2019","unstructured":"Karatekin A\u00d6, Kele\u015f A, Gen\u00e7o\u011flu N. Comparison of continuous wave and cold lateral condensation filling techniques in 3D printed simulated C-shape canals instrumented with Reciproc Blue or Hyflex EDM. PLoS ONE. 2019;14:e0224793.","journal-title":"PLoS ONE"},{"key":"4518_CR28","doi-asserted-by":"publisher","first-page":"445","DOI":"10.5005\/jp-journals-10024-1870","volume":"17","author":"Y Mohammad","year":"2016","unstructured":"Mohammad Y, Alafif H, Hajeer MY, Yassin O. An evaluation of GuttaFlow2 in filling artificial internal resorption cavities: an in vitro study. J Contemp Dent Pract. 2016;17:445\u201350.","journal-title":"J Contemp Dent Pract"},{"key":"4518_CR29","doi-asserted-by":"publisher","first-page":"1030","DOI":"10.1016\/j.joen.2019.04.012","volume":"45","author":"X Zhong","year":"2019","unstructured":"Zhong X, Shen Y, Ma J, Chen WX, Haapasalo M. Quality of root filling after obturation with gutta-percha and 3 different sealers of minimally instrumented root canals of the maxillary first molar. J Endod. 2019;45:1030\u20135.","journal-title":"J Endod"},{"key":"4518_CR30","doi-asserted-by":"publisher","first-page":"e566","DOI":"10.4317\/jced.59387","volume":"14","author":"CF Girelli","year":"2022","unstructured":"Girelli CF, Lacerda MF, Lemos CA, et al. The thermoplastic techniques or single-cone technique on the quality of root canal filling with tricalcium silicate-based sealer: an integrative review. J Clin Exp Dent. 2022;14:e566\u201372.","journal-title":"J Clin Exp Dent"},{"key":"4518_CR31","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/j.joen.2023.10.014","volume":"50","author":"AJS Torres-Carrillo","year":"2024","unstructured":"Torres-Carrillo AJS, Assis HC, Salazar-Gamarra RE, Teodosio LM, Silva-Sousa AC, Mazzi-Chaves JF, Ferreira-Soares PB, Sousa-Neto MD, Lopes-Olh\u00ea FC. Evaluation of different techniques and materials for filling in 3-dimensional printed teeth replicas with Perforating Internal Resorption by means of Micro-computed Tomography. J Endod. 2024;50:205\u201312.","journal-title":"J Endod"},{"key":"4518_CR32","doi-asserted-by":"crossref","unstructured":"\u00d6zer SY, \u00d6zkan HD, Oyucu \u0130. Evaluation of different Root Canal Obturation techniques in Internal Root Resorption of three-dimensional printed teeth manufactured using Computer Software. 3D print addit manuf. 202;9:503\u201310.","DOI":"10.1089\/3dp.2021.0012"},{"key":"4518_CR33","unstructured":"Sharki AM, Ali AH. Three-dimensional measurement of Obturation Quality of Bioceramic materials in filling Artificial Internal Root Resorption cavities using different obturation techniques: an in Vitro comparative study. J Endod. 2024:S0099-2399(24)00226-7."},{"key":"4518_CR34","doi-asserted-by":"publisher","first-page":"2407","DOI":"10.1007\/s00784-023-04884-9","volume":"27","author":"C Kooanantkul","year":"2023","unstructured":"Kooanantkul C, Shelton RM, Camilleri J. Comparison of obturation quality in natural and replica teeth root-filled using different sealers and techniques. Clin Oral Investig. 2023;27:2407\u201317.","journal-title":"Clin Oral Investig"},{"key":"4518_CR35","first-page":"497","volume":"110","author":"MF Haridy","year":"2022","unstructured":"Haridy MF, Ahmed HS, Kataia MM, et al. Fracture resistance of root canal-treated molars restored with ceramic overlays with\/without different resin composite base materials: an in vitro study. Odont. 2022;110:497\u2013507.","journal-title":"Odont"},{"key":"4518_CR36","doi-asserted-by":"publisher","first-page":"836","DOI":"10.1111\/j.1365-2591.2008.01434.x","volume":"41","author":"N Gencoglu","year":"2008","unstructured":"Gencoglu N, Yildirim T, Garip Y, Karagenc B, Yilmaz H. Effectiveness of different gutta-percha techniques when filling experimental internal resorptive cavities. Int Endod J. 2008;41:836\u201342.","journal-title":"Int Endod J"},{"key":"4518_CR37","unstructured":"Alemam S, Abuelsadat S, Saber S, Elsewify T. (2020). Accuracy, sensitivity and specificity of three imaging modalities in detection of separated intracanal instruments. Italian Endod J 2020;34:97\u2013103."}],"container-title":["BMC Oral Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12903-024-04518-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12903-024-04518-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12903-024-04518-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,13]],"date-time":"2024-07-13T01:01:45Z","timestamp":1720832505000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcoralhealth.biomedcentral.com\/articles\/10.1186\/s12903-024-04518-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,13]]},"references-count":37,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["4518"],"URL":"https:\/\/doi.org\/10.1186\/s12903-024-04518-w","relation":{},"ISSN":["1472-6831"],"issn-type":[{"value":"1472-6831","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,13]]},"assertion":[{"value":"26 April 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 June 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 July 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"This study has been approved by the research ethics committee of Ain Shams University (Cairo, Egypt) under approval no. FDASU-REC PC 112353.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"<!--Emphasis Type='Bold' removed-->Ethics approval and consent to participate"}}],"article-number":"784"}}