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Among materials proposed for minimising this remodelling and preserving the bone, autologous dental tissue is a promising option, but more data are needed. In this context, we evaluated size and density changes using cone beam computed tomography in autologous dental material (ADM)-preserved sockets compared to controls, and assessed biological responses by histological analysis.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A split-mouth study was conducted including 22 patients, who underwent removal of \u2265\u20092 single-rooted teeth with intact sockets, assigning one socket to the experimental group which received ADM for alveolar preservation and another to the control group, which only underwent blood clot stabilisation. Cone beam computed tomography was performed postoperatively (week 0) and at weeks 8 and 16 to assess socket size and bone density. Histological analysis was carried out on trephine biopsies taken (\u00d84\u2009\u00d7\u20094.5\u00a0mm) from the experimental group.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Less horizontal shrinkage was observed in the ADM group, especially at week 16 considering the group-by-time interaction for the following variables: difference in height between the lingual and buccal alveolar crests (-1.00; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01; 95% CI: -0.28 \u2013 -1.73), and half-widths, measured as the distance from the long axis of the missing tooth to the buccal alveolar crest at 1\u00a0mm (-0.61; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01; 95% CI: -0.18 \u2013 -1.04) and at 3\u00a0mm (-0.56; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01; 95% CI: -0.15 \u2013 -0.97) below the crest, with mean decreases of 1.07 and 2.14\u00a0mm in height difference, 0.66 and 1.32\u00a0mm in half-width at 1\u00a0mm and 0.43 and 1.02\u00a0mm in half-width at 3\u00a0mm in ADM and control groups respectively. Densitometry analysis showed higher bone densities in Hounsfield units in the ADM group considering all factors analysed regardless of time point and socket third (coronal, middle, or apical). Histologically, there were no signs of inflammation or foreign body reaction, and dentin particles were surrounded by and in close contact with bone tissue.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>These results add to the evidence that dentin can be used successfully as a material for alveolar socket preservation, given its desirable mechanical and biological properties, and warrant larger studies.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12903-024-04576-0","type":"journal-article","created":{"date-parts":[[2024,7,23]],"date-time":"2024-07-23T05:01:53Z","timestamp":1721710913000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Use of autologous tooth-derived material as a graft in the post-extraction socket. 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