{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:04:46Z","timestamp":1792800286160,"version":"4.5.0"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,10,19]],"date-time":"2024-10-19T00:00:00Z","timestamp":1729296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,10,19]],"date-time":"2024-10-19T00:00:00Z","timestamp":1729296000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Misr International University","id":[{"id":"https:\/\/ror.org\/030vg1t69","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Oral Health"],"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n The current trial evaluated the midfacial gingival margin changes, volumetric, radiographic and clinical alterations 1-year following immediate implant placement with customized healing abutment (IIP\u2009+\u2009CHA) either solely, or in combination with xenograft (IIP\u2009+\u2009Bonegraft) or with connective tissue grafting (IIP\u2009+\u2009CTG) at sites with thin labial bone in the esthetic zone.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Thirty-nine non-restorable maxillary teeth indicated for extraction in the esthetic zone were included. Participants were randomly assigned into three equal group; IIP\u2009+\u2009Bonegraft (Control), IIP\u2009+\u2009CTG and IIP\u2009+\u2009CHA. Midfacial gingival margin changes(mm) as primary outcome, labial soft tissue contour change(mm), interdental tissue height changes and total volume(mm\n 3<\/jats:sup>\n ) were assessed. Amount of bone labial to the implant and crestal bone level changes were also recorded. All outcomes were measured 1-year post-operative.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The midfacial gingival margin changes demonstrated a significant difference (\n P<\/jats:italic>\n \u2009\u2264\u20090.05) between the groups showing -0.98, -0.74 and -1.54\u00a0mm in sites treated with IIP\u2009+\u2009Bone graft, IIP\u2009+\u2009CTG and IIP\u2009+\u2009CHA respectively after1-year. While labial soft tissue contour change (mm), total volume (mm\n 3<\/jats:sup>\n ) and distal interdental tissue height changes (mm) revealed a significant difference after one-year between the studied groups, yet mesial interdental tissue height changes showed no difference (\n P<\/jats:italic>\n \u2009>\u20090.05). Both IIP\u2009+\u2009Bone graft and IIP\u2009+\u2009CHA groups revealed a significant positive correlation between the total volume loss (mm\n 3<\/jats:sup>\n ) after 1 year and mid-facial gingival margin changes (\n P<\/jats:italic>\n \u2009\u2264\u20090.05). However, no significant correlation was observed in the IIP\u2009+\u2009CTG group (\n P<\/jats:italic>\n \u2009=\u20090.63). CBCT measurements showed a significant difference in crestal bone changes between the three groups (\n P<\/jats:italic>\n \u2009\u2264\u20090.05), yet, there was no significant difference regarding mean amount of bone labial to the implant(\n P<\/jats:italic>\n \u2009>\u20090.05).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n This investigation suggests that the mere presence of CTG simultaneous with IIP in the anterior maxilla reduced the midfacial gingival margin alterations (mm), besides, CTG decreased the overall volume loss (mm\n 3<\/jats:sup>\n ) by 5-folds compared to the other studied groups after one year. Meanwhile, using CHA alone with IIP failed to maintain the peri-implant soft tissues contour.\n <\/jats:p>\n <\/jats:sec>\n \n Trial registration<\/jats:title>\n The current trial was retrospectively registered at Clinical trials.gov (ID: NCT05975515, Date: 27-July-2023).<\/jats:p>\n <\/jats:sec>","DOI":"10.1186\/s12903-024-04845-y","type":"journal-article","created":{"date-parts":[[2024,10,19]],"date-time":"2024-10-19T10:02:04Z","timestamp":1729332124000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Effect of soft tissue volume on midfacial gingival margin alterations following immediate implant placement in the esthetic zone: a 1-year randomized clinical and volumetric trial"],"prefix":"10.1186","volume":"24","author":[{"given":"Ahmed Ibrahim Aboul","family":"Fettouh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noha Ayman","family":"Ghallab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled Abdel","family":"Ghaffar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azza Ezz","family":"Elarab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nourhan Gamal","family":"Abdel-Aziz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nael Adel","family":"Mina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nesma Mohamed","family":"Shemais","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omnia Aboul","family":"Dahab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,10,19]]},"reference":[{"issue":"Suppl","key":"4845_CR1","first-page":"216","volume":"29","author":"D Morton","year":"2014","unstructured":"Morton D, Chen ST, Martin WC, Levine RA, Buser D. 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J Clin Periodontol. 2018;45(2):253\u201364.","journal-title":"J Clin Periodontol"}],"container-title":["BMC Oral Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12903-024-04845-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12903-024-04845-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12903-024-04845-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T14:04:12Z","timestamp":1729519452000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcoralhealth.biomedcentral.com\/articles\/10.1186\/s12903-024-04845-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,19]]},"references-count":43,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["4845"],"URL":"https:\/\/doi.org\/10.1186\/s12903-024-04845-y","relation":{},"ISSN":["1472-6831"],"issn-type":[{"value":"1472-6831","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,19]]},"assertion":[{"value":"17 July 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 September 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 October 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study protocol was carried out in accordance with the Declaration of Helsinki principles of 1975, as revised in 2013, and approved by approved by the Research Ethics Committee, Faculty of Dentistry, Cairo University (No 16\u20131-22). Written informed consent was obtained from all individuals included in the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}],"article-number":"1256"}}