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The study objectives were to investigate the impact of implant position, in lateral incisors or canine positions, on peri-implant bone loss and posterior ridge resorption.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Fifty patients with mandibular two-implants were recalled and divided according to the implant position into two groups (group L: implants in lateral incisor positions and group C: implants in canine positions). The circumferential peri-implant bone level and posterior ridge resorption were assessed at implant insertion (T0), one year later (T1), and five years later (T5) using the follow-up CBCT. Data were analyzed using the Statistical Package of Social Science (SPSS) program. A Mann-Whitney test was used to compare two different groups. Paired groups were compared using the Wilcoxon signed-rank test. The threshold of significance is fixed at a 5% level (p-value).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Significant differences in the vertical bone loss between groups appeared at (T5 - T1) (Mann Whitney test, (<jats:italic>P<\/jats:italic>\u2009=\u20090.01)) and at (T5 - T0) (Mann Whitney test, (<jats:italic>P<\/jats:italic>\u2009=\u20090.005)), and a significant difference in horizontal bone loss between groups was found at (T1 - T0) (Mann Whitney test, (<jats:italic>P<\/jats:italic>\u2009=\u20090.041)) and (T5 - T1) (Mann Whitney test, (<jats:italic>P<\/jats:italic>\u2009=\u20090.041)). Also, there were significant differences over the evaluation period between groups at certain points along the ridge at M1 (Mann Whitney test, (<jats:italic>P<\/jats:italic>\u2009=\u20090.021)), M3 (Mann Whitney test, (<jats:italic>P<\/jats:italic>\u2009=\u20090.008)), and M4 (Mann Whitney test, (<jats:italic>P<\/jats:italic>\u2009=\u20090.015)).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>According to the findings of this clinical study, the placement of implants in the lateral incisor position for two implant-retained overdentures is a viable choice. In comparison to the canine position, the lateral incisor position demonstrated superior peri-implant responses, which could potentially enhance the longevity of the implants. Furthermore, the placement of implants in the lateral incisor position can promote a more even distribution of stress and help mitigate posterior ridge resorption. Conversely, implants in the canine position may cause a seesaw effect and result in greater posterior ridge resorption.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Clinical Trial Registry Number<\/jats:title>\n                <jats:p>(NCT06055842) (13\/03\/2024).<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12903-024-04871-w","type":"journal-article","created":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T17:02:44Z","timestamp":1727715764000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effect of different implant positions for two implant-retained mandibular overdenture: a retrospective 5-years radiographic evaluation of the circumferential peri-implant bone loss and posterior ridge resorptive changes"],"prefix":"10.1186","volume":"24","author":[{"given":"Khloud Ezzat","family":"Mourad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radwa Mohsen Kamal","family":"Emera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Habib","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,9,30]]},"reference":[{"issue":"2","key":"4871_CR1","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1111\/clr.12531","volume":"27","author":"JS Kern","year":"2016","unstructured":"Kern JS, Kern T, Wolfart S, Heussen N. 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Article J Dentistry. 2018;5(15):59\u201363.","journal-title":"Article J Dentistry"}],"container-title":["BMC Oral Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12903-024-04871-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12903-024-04871-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12903-024-04871-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T18:02:33Z","timestamp":1727719353000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcoralhealth.biomedcentral.com\/articles\/10.1186\/s12903-024-04871-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,30]]},"references-count":48,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["4871"],"URL":"https:\/\/doi.org\/10.1186\/s12903-024-04871-w","relation":{},"ISSN":["1472-6831"],"issn-type":[{"value":"1472-6831","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,30]]},"assertion":[{"value":"14 June 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 September 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 September 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Approval to conduct this study was given by the Institution Ethics Committee, the Faculty of Dentistry, Mansoura University, Egypt (M0108023RP) and retrospectively registered at  (NCT06055842) (13\/03\/2024). Participants\u2019 agreements were taken by signing the informed consent to undergo treatment.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not Applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Written consent was obtained from all participants.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"1161"}}