{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T17:05:27Z","timestamp":1784826327923,"version":"3.55.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T00:00:00Z","timestamp":1736294400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T00:00:00Z","timestamp":1736294400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Oral Health"],"DOI":"10.1186\/s12903-024-05400-5","type":"journal-article","created":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T13:56:16Z","timestamp":1736344576000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Microinvasive interventions in the management of proximal caries lesions in primary and permanent teeth- systematic review and meta-analysis"],"prefix":"10.1186","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9087-1453","authenticated-orcid":false,"given":"Robina","family":"Tasleem","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4017-1694","authenticated-orcid":false,"given":"Saleh Ali","family":"Alqahtani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3343-9397","authenticated-orcid":false,"given":"Naif","family":"Abogazalah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hussain","family":"Almubarak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ammara","family":"Riaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarosh Sher","family":"Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeeshan","family":"Allana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,8]]},"reference":[{"key":"5400_CR1","unstructured":"Rathee M, Sapra A. Dental Caries. [Updated 2023 Jun 21]. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2024 Jan. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK551699\/."},{"issue":"12","key":"5400_CR2","doi-asserted-by":"publisher","first-page":"7114","DOI":"10.3390\/ijerph19127114","volume":"19","author":"M Yousaf","year":"2022","unstructured":"Yousaf M, Aslam T, Saeed S, Sarfraz A, Sarfraz Z, Cherrez-Ojeda I. Individual, family, and socioeconomic contributors to dental caries in children from low- and middle- income countries. Int J Environ Res Public Health. 2022;19(12):7114. https:\/\/doi.org\/10.3390\/ijerph19127114. PMID: 35742362; PMCID: PMC9222700.","journal-title":"Int J Environ Res Public Health."},{"key":"5400_CR3","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1111\/iej.13080","volume":"52","author":"HF Duncan","year":"2019","unstructured":"Duncan HF, Galler K, Tomson PL, Simon S, El-Karim I, Kundzina R, Krastl G, Dammaschke T, Fransson H, Markvart M. European Society of Endodontology position statement: management of deep caries and the exposed pulp. Int Endodontic J. 2019;52:923\u201334.","journal-title":"Int Endodontic J."},{"issue":"1","key":"5400_CR4","first-page":"9365845","volume":"2023","author":"A Warreth","year":"2023","unstructured":"Warreth A. Dental caries and its management. Int J Dent. 2023;2023(1):9365845.","journal-title":"Int J Dent"},{"key":"5400_CR5","doi-asserted-by":"publisher","unstructured":"Tinanoff N. Dental caries. Pediatric dentistry 2019 (169\u2013179). Elsevier. https:\/\/doi.org\/10.1016\/B978-0-323-60826-8.00012-2.","DOI":"10.1016\/B978-0-323-60826-8.00012-2"},{"key":"5400_CR6","unstructured":"Lennon S, Duncan HF. Minimally invasive endodontics-pulp fact or pulp fiction? J Ir Dent Assoc. 2020;66(3):134\u201338."},{"issue":"7","key":"5400_CR7","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1111\/iej.13128","volume":"52","author":"L Bj\u00f8rndal","year":"2019","unstructured":"Bj\u00f8rndal L, Simon S, Tomson PL, Duncan HF. Management of deep caries and the exposed pulp. Int Endod J. 2019;52(7):949\u201373. https:\/\/doi.org\/10.1111\/iej.13128.","journal-title":"Int Endod J"},{"issue":"12","key":"5400_CR8","doi-asserted-by":"publisher","first-page":"147","DOI":"10.3390\/dj9120147","volume":"9","author":"H Desai","year":"2021","unstructured":"Desai H, Stewart CA, Finer Y. Minimally invasive therapies for the management of dental caries-a literature review. Dent J (Basel). 2021;9(12):147. https:\/\/doi.org\/10.3390\/dj9120147.","journal-title":"Dent J (Basel)"},{"key":"5400_CR9","doi-asserted-by":"publisher","first-page":"1623","DOI":"10.1007\/s00784-020-03201-y","volume":"24","author":"CH Splieth","year":"2020","unstructured":"Splieth CH, Kanzow P, Wiegand A, Schmoeckel J, Jablonski-Momeni A. How to intervene in the caries process: proximal caries in adolescents and adults\u2014a systematic review and meta-analysis. Clin Oral Invest. 2020;24:1623\u201336.","journal-title":"Clin Oral Invest"},{"key":"5400_CR10","doi-asserted-by":"publisher","first-page":"241","DOI":"10.22271\/oral.2023.v9.i3d.1812","volume":"9","author":"YM Valdes","year":"2023","unstructured":"Valdes YM, Cepeda SE, Moyeda AL, Ibarra KI, Zu\u00f1iga LM, Lopez JF. Minimally invasive treatments for pediatric dentistry. Int J Appl Dent Sci. 2023;9:241\u20134.","journal-title":"Int J Appl Dent Sci"},{"key":"5400_CR11","unstructured":"American Dental Association. Dental Radiographic examinations: recommendations for patient selection and limiting Radiation exposure. Chicago: US Department of Health and Human Services; 2024."},{"key":"5400_CR12","doi-asserted-by":"publisher","first-page":"l4898","DOI":"10.1136\/bmj.l4898","volume":"366","author":"JAC Sterne","year":"2019","unstructured":"Sterne JAC, Savovi\u0107 J, Page MJ, Elbers RG, Blencowe NS, Boutron I, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ. 2019;366:l4898.","journal-title":"BMJ"},{"key":"5400_CR13","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1007\/s00784-017-2135-x","volume":"22","author":"RA Arthur","year":"2018","unstructured":"Arthur RA, Zenkner JE, d\u2019Ornellas Pereira J\u00fanior JC, Correia RT, Alves LS, Maltz M. Proximal carious lesions infiltration\u2014a 3-year follow-up study of a randomized controlled clinical trial. Clin Oral Invest. 2018;22:469\u201374.","journal-title":"Clin Oral Invest"},{"issue":"3","key":"5400_CR14","first-page":"195","volume":"40","author":"SM Bagher","year":"2018","unstructured":"Bagher SM, Hegazi FM, Finkelman M, Ramesh A, Gowharji N, Swee G, Felemban O, Loo CY. Radiographic effectiveness of resin infiltration in arresting incipient proximal enamel lesions in primary molars. Pediatr Dentistry. 2018;40(3):195\u2013200.","journal-title":"Pediatr Dentistry"},{"issue":"1","key":"5400_CR15","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1111\/ipd.13011","volume":"33","author":"Y Treeratweerapong","year":"2023","unstructured":"Treeratweerapong Y, Nakornchai S, Jirarattanasopha V. Effectiveness of applying proximal enamel caries with fluoride-releasing sealant and fluoride varnish on caries progression in permanent teeth: a 12-month split-mouth randomized clinical trial. Int J Pediatr Dent. 2023;33(1):30\u20139.","journal-title":"Int J Pediatr Dent"},{"issue":"3","key":"5400_CR16","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1177\/2380084417699400","volume":"2","author":"LA Foster Page","year":"2017","unstructured":"Foster Page LA, Beckett D, Ahmadi R, et al. Resin Infiltration of Caries in primary molars in a community setting: 24-Month Randomized Controlled Trial findings. JDR Clin Translational Res. 2017;2(3):287\u201394.","journal-title":"JDR Clin Translational Res"},{"issue":"2","key":"5400_CR17","first-page":"110","volume":"15","author":"CS Sarti","year":"2020","unstructured":"Sarti CS, Vizzotto MB, Filgueiras LV, Bonif\u00e1cio CC, Rodrigues JA. Two-year split-mouth randomized controlled clinical trial on the progression of proximal carious lesions on primary molars after resin infiltration. Pediatr Dent. 2020;15(2):110\u20135.","journal-title":"Pediatr Dent"},{"issue":"90","key":"5400_CR18","doi-asserted-by":"publisher","first-page":"103184","DOI":"10.1016\/j.jdent.2019.103184","volume":"1","author":"RC Jorge","year":"2019","unstructured":"Jorge RC, Ammari MM, Soviero VM, Souza IP. Randomized controlled clinical trial of resin infiltration in primary molars: 2 years follow-up. J Dent. 2019;1(90):103184.","journal-title":"J Dent"},{"issue":"7","key":"5400_CR19","doi-asserted-by":"publisher","first-page":"1164","DOI":"10.3390\/children10071164","volume":"10","author":"JA Khan","year":"2023","unstructured":"Khan JA, Alamoudi NM, El-Ashiry EA, Felemban OM, Bagher SM. Effect of Light- Curable Resin-Modified Glass Ionomer Varnish on Non-Cavitated Proximal Caries Lesions in Primary Molars: A Randomized Controlled Trial. Children. 2023;10(7):1164.","journal-title":"Children"},{"issue":"13","key":"5400_CR20","doi-asserted-by":"publisher","first-page":"1497","DOI":"10.1177\/0022034519876853","volume":"98","author":"MC Peters","year":"2019","unstructured":"Peters MC, Hopkins AR Jr, Zhu L, Yu Q. Efficacy of proximal resin infiltration on caries inhibition: results from a 3-year randomized controlled clinical trial. J Dent Res. 2019;98(13):1497\u2013502.","journal-title":"J Dent Res"},{"issue":"3","key":"5400_CR21","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1159\/000503053","volume":"29","author":"S Arslan","year":"2020","unstructured":"Arslan S, Kaplan MH. The effect of resin infiltration on the progression of proximal caries lesions: a randomized clinical trial. Med Principles Pract. 2020;29(3):238\u201343.","journal-title":"Med Principles Pract."},{"issue":"93","key":"5400_CR22","doi-asserted-by":"publisher","first-page":"103277","DOI":"10.1016\/j.jdent.2020.103277","volume":"1","author":"S Paris","year":"2020","unstructured":"Paris S, Bitter K, Krois J, Meyer-L\u00fcckel H. Seven-year-efficacy of proximal caries infiltration\u2013Randomized clinical trial. Journal of dentistry. 2020;1(93):103277.","journal-title":"Journal of dentistry"},{"issue":"5","key":"5400_CR23","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1177\/0022034516629116","volume":"95","author":"H Meyer-Lueckel","year":"2016","unstructured":"Meyer-Lueckel H, Balbach A, Schikowsky C, Bitter K, Paris S. Pragmatic RCT on the efficacy of proximal caries infiltration. J Dent Res. 2016;95(5):531\u20136.","journal-title":"J Dent Res"},{"key":"5400_CR24","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.jdent.2018.09.005","volume":"79","author":"MC Peters","year":"2018","unstructured":"Peters MC, Hopkins AR Jr, Yu Q. Resin infiltration: an effective adjunct strategy for managing high caries risk-A within-person randomized controlled clinical trial. J Centistry. 2018;79:24\u201330.","journal-title":"J Centistry"},{"issue":"4","key":"5400_CR25","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1159\/000470851","volume":"51","author":"CP Basili","year":"2017","unstructured":"Basili CP, Emilson CG, Corvalan GC, et al. Preventive and therapeutic proximal sealing: a 3.5-Year randomized controlled clinical Trial Follow-Up. Caries Res. 2017;51(4):387\u201393.","journal-title":"Caries Res"},{"issue":"1","key":"5400_CR26","doi-asserted-by":"publisher","first-page":"53","DOI":"10.5005\/jp-journals-10005-1579","volume":"12","author":"V Manoharan","year":"2019","unstructured":"Manoharan V, Kumar SA, Arumugam SB, Anand V, Krishnamoorthy S, Methippara JJ. Is resin infiltration a microinvasive approach to white lesions of calcified tooth structures? A systemic review. Int J Clin Pediatr Dentistry. 2019;12(1):53.","journal-title":"Int J Clin Pediatr Dentistry"},{"key":"5400_CR27","doi-asserted-by":"crossref","unstructured":"Krois J, Goestemeyer G, Reda S, Schwendicke F. Sealing or infiltrating proximal carious lesions. J Dent. 2018;74:15\u201322.","DOI":"10.1016\/j.jdent.2018.04.026"},{"key":"5400_CR28","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.jdent.2018.04.026","volume":"74","author":"YM Valdes","year":"2018","unstructured":"Valdes YM, Cepeda SE, Moyeda AL, Ibarra KI, Zu\u00f1iga LM, Lopez JF. Minimally invasive treatments for pediatric dentistry. Int J Appl Dent Sci. 2023;9:241\u20134.","journal-title":"J Dent"},{"key":"5400_CR29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12903-020-01364-4","volume":"21","author":"Y Chen","year":"2021","unstructured":"Chen Y, Chen D, Lin H. Infiltration and sealing for managing non-cavitated proximal lesions: a systematic review and meta-analysis. BMC Oral Health. 2021;21:1\u201321. https:\/\/doi.org\/10.1186\/s12903-020-01364-4.","journal-title":"BMC Oral Health"}],"container-title":["BMC Oral Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12903-024-05400-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12903-024-05400-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12903-024-05400-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T14:02:24Z","timestamp":1736344944000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcoralhealth.biomedcentral.com\/articles\/10.1186\/s12903-024-05400-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,8]]},"references-count":29,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["5400"],"URL":"https:\/\/doi.org\/10.1186\/s12903-024-05400-5","relation":{},"ISSN":["1472-6831"],"issn-type":[{"value":"1472-6831","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,8]]},"assertion":[{"value":"7 August 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"48"}}