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Clinical evaluations were carried out for 6 postoperative weeks for the assessment of pain, Intra-fragmentary mobility, occlusion, wound healing complications, and an objective mental nerve neurosensory function. Radiographic assessment for the mean bone density was performed immediately after surgery and at 12 postoperative weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Result<\/jats:title>\n                    <jats:p>\n                      By the end of the follow-up period, all cases reported a lack of intra-fragmentary mobility, proper occlusion, a significant reduction in pain intensity scores, and proper wound healing. Objective nerve testing reported a statistically significant improvement across the clinical follow-up period in both sides; however, one patient reported Level C sensation in the 2MPs side (4.17%) at the 6th postoperative week. Both sides showed a significant increase in mean bone density at 12 weeks (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001\n                      <jats:sup>*<\/jats:sup>\n                      ), with the 3D-IMP side demonstrating a significantly higher bone density (1107.4\u2009\u00b1\u2009142.2 HU) than the 2MPs side (960.9\u2009\u00b1\u200997.58 HU).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>3D Interlocking miniplates proved to be an effective alternative to conventional miniplates for mandibular parasymphyseal fractures near the MF, offering enhanced bone healing and better neurosensory outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration<\/jats:title>\n                    <jats:p>\n                      Trial was retrospectively registered at clinicaltrials.gov [\n                      <jats:italic>NCT06939010<\/jats:italic>\n                      \/2025-4-22].\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12903-026-07799-5","type":"journal-article","created":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T08:46:44Z","timestamp":1774774004000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Three-dimensional Interlocking versus conventional miniplates for mandibular fractures fixation near the mental foramen: a split-mouth randomized clinical trial"],"prefix":"10.1186","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-8442-2810","authenticated-orcid":false,"given":"Ibrahim Mohamed","family":"Abdelhamed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed Ossama","family":"Sweedan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reem M.","family":"Ismail","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4432-9978","authenticated-orcid":false,"given":"Yehia","family":"El-Mahallawy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,29]]},"reference":[{"key":"7799_CR1","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1055\/s-0041-1735818","volume":"35","author":"K Panesar","year":"2021","unstructured":"Panesar K, Susarla SM. 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All patients signed informed consent before the start of the treatment protocol. All methods were carried out per Helsinki Declaration guidelines. The study was registered retrospectively in clinicaltrials.gov\/\n                      NCT06939010\n                      \/2025-4-22.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"709"}}