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Informed consent was obtained from all participants after explaining the study objectives and procedures prior to their enrollment. This trial was retrospectively registered on ClinicalTrials.gov due to an administrative oversight; however, the protocol and primary outcomes were fully pre-defined and approved by the ethics committee prior to patient enrollment [#NCT07106307 (07\/12\/2025)].","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval and Consent to Participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"1164"}}