{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T03:00:31Z","timestamp":1784862031845,"version":"3.55.0"},"reference-count":60,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T00:00:00Z","timestamp":1779062400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T00:00:00Z","timestamp":1784851200000},"content-version":"vor","delay-in-days":67,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Oral Health"],"DOI":"10.1186\/s12903-026-08595-x","type":"journal-article","created":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T11:45:02Z","timestamp":1779104702000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of demineralization around orthodontic brackets bonded with different adhesive agents on fatigue-based shear bond strength: an in vitro comparative study"],"prefix":"10.1186","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-2670-5360","authenticated-orcid":false,"given":"Deniz","family":"Arslan Aydo\u011fan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8172-6043","authenticated-orcid":false,"given":"Orhan","family":"Cicek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9120-1673","authenticated-orcid":false,"given":"Mehmet","family":"Yetmez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,18]]},"reference":[{"issue":"4","key":"8595_CR1","doi-asserted-by":"publisher","first-page":"S56","DOI":"10.1016\/j.ajodo.2015.01.011","volume":"147","author":"P Gange","year":"2015","unstructured":"Gange P. The evolution of bonding in orthodontics. Am J Orthod Dentofac Orthop. 2015;147(4):S56\u201363.","journal-title":"Am J Orthod Dentofac Orthop"},{"issue":"12","key":"8595_CR2","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1016\/0002-9416(65)90203-4","volume":"51","author":"GV Newman","year":"1965","unstructured":"Newman GV. Epoxy adhesives for orthodontic attachments: progress report. Am J Orthod. 1965;51(12):901\u201312.","journal-title":"Am J Orthod"},{"issue":"6","key":"8595_CR3","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1177\/00220345550340060801","volume":"34","author":"MG Buonocore","year":"1955","unstructured":"Buonocore MG. A simple method of increasing the adhesion of acrylic filling materials to enamel surfaces. J Dent Res. 1955;34(6):849\u201353.","journal-title":"J Dent Res"},{"issue":"6","key":"8595_CR4","doi-asserted-by":"publisher","first-page":"205","DOI":"10.4236\/ojst.2018.86020","volume":"8","author":"Y Shapinko","year":"2018","unstructured":"Shapinko Y, Eleftheriadi I, Brosh T, Adler-Abramovich L, Davidovitch M, Sella-Tunis T, Sarig R, Shpack N. Evaluation of an orthodontic adhesive with combined primer and composite. Open J Stomatol. 2018;8(6):205\u201316.","journal-title":"Open J Stomatol"},{"issue":"1","key":"8595_CR5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41405-023-00181-5","volume":"10","author":"M Boudrot","year":"2024","unstructured":"Boudrot M, Fran\u00e7ois P, Abdel-Gawad S, Attal J-P, Dantagnan C-A. Shear bond strength of a RMGIC for orthodontic bracket bonding to enamel. BDJ Open. 2024;10(1):1.","journal-title":"BDJ Open"},{"issue":"1","key":"8595_CR6","first-page":"35","volume":"39","author":"S Bahrami","year":"2023","unstructured":"Bahrami S, Azarbayejani S, Kazemian M. Comparative evaluation of shear bond strength and debonding properties of GC ortho connect composite and transbond XT composite. Aust Orthod J. 2023;39(1):35\u201341.","journal-title":"Aust Orthod J"},{"issue":"1","key":"8595_CR7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.46889\/JDHOR.2025.6203","volume":"6","author":"ERN S\u00e1nchez","year":"2025","unstructured":"S\u00e1nchez ERN, Romero HAM, Rasc\u00f3n AN. Comparison of bond strength among three direct bonding systems for metal brackets in orthodontics: a systematic review and meta-analysis. J Dent Health Oral Res. 2025;6(1):1\u201322.","journal-title":"J Dent Health Oral Res"},{"key":"8595_CR8","doi-asserted-by":"publisher","unstructured":"Hu H, Li C, Li F, Chen J, Sun J, Zou S, Sandham A, Xu Q, Riley P, Ye Q. Enamel etching for bonding fixed orthodontic braces. Cochrane Database Syst Reviews. 2013(11). https:\/\/doi.org\/10.1002\/14651858.CD005516.pub2.","DOI":"10.1002\/14651858.CD005516.pub2"},{"issue":"4","key":"8595_CR9","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/j.jdent.2011.01.010","volume":"39","author":"I S\u00e1nchez","year":"2011","unstructured":"S\u00e1nchez I, Uzc\u00e1tegui G. Fractals in dentistry. J Dent. 2011;39(4):273\u201392.","journal-title":"J Dent"},{"key":"8595_CR10","unstructured":"Powers JM, Messersmith ML. Enamel etching and bond strength. In: Orthodontic materials: scientific and clinical aspects. edn. Edited by Brantley W, Eliades T. Stuttgart, Germany: Thieme; 2001. p. 105\u2013122."},{"issue":"2","key":"8595_CR11","first-page":"43","volume":"58","author":"W Bakhadher","year":"2015","unstructured":"Bakhadher W, Halawany H, Talic N, Abraham N, Jacob V. Factors affecting the shear bond strength of orthodontic brackets - a review of in vitro studies. Acta Med. 2015;58(2):43\u20138.","journal-title":"Acta Med"},{"issue":"1","key":"8595_CR12","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/s40563-020-00129-0","volume":"8","author":"S Liu","year":"2020","unstructured":"Liu S, Zhu Y, Gegen T. Micromorphological analysis and bond strength comparison of two adhesives for different degrees of dental fluorosis. Appl Adhes Sci. 2020;8(1):6.","journal-title":"Appl Adhes Sci"},{"issue":"10","key":"8595_CR13","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.17219\/acem\/174444","volume":"33","author":"I Du\u015b-Ilnicka","year":"2024","unstructured":"Du\u015b-Ilnicka I, Jedli\u0144ski M, Padella S, Corridore D, Mazur M. Fixed appliances orthodontic therapy as a risk factor for caries development: systematic review. Adv Clin Exp Med. 2024;33(10):1153\u201361.","journal-title":"Adv Clin Exp Med"},{"key":"8595_CR14","doi-asserted-by":"publisher","unstructured":"Rosa DC, De Almeida Neves T, Azcarate-Peril A, Divaris M, Wu K, Cho D, Moss H, Paster K, Chen B, Freitas-Fernandes T. L : The bacterial microbiome and metabolome in caries progression and arrest. J Oral Microbiol. 2021;13(1886748). https:\/\/doi.org\/10.1080\/20002297.2021.1886748.","DOI":"10.1080\/20002297.2021.1886748"},{"key":"8595_CR15","doi-asserted-by":"publisher","unstructured":"Al-Blaihed D, Meligy OE, Baghlaf K, Aljawi R, Abudawood S. White spot lesions in fixed orthodontics: A literature review on etiology, prevention, and treatment. Cureus. 2024;16(7):e65679. https:\/\/doi.org\/10.7759\/cureus.65679.","DOI":"10.7759\/cureus.65679"},{"key":"8595_CR16","doi-asserted-by":"publisher","unstructured":"Marya A, Venugopal A, Karobari M, Rokaya D. White spot lesions: A serious but often ignored complication of orthodontic treatment. Open Dent J. 2022;16( e187421062202230). https:\/\/doi.org\/10.2174\/18742106-v16-e2202230.","DOI":"10.2174\/18742106-v16-e2202230"},{"key":"8595_CR17","unstructured":"Zachrisson BU, Usumez S, B\u00fcy\u00fcky\u0131lmaz T. Bonding in Orthodontics. In: Orthodontics: current principles and techniques. 6th edn. Edited by Graber LW, Vanarsdall RL, Vig KW, Huang GJ. St. Louis, MO: Elsevier Health Sciences; 2017. p. 305\u2013336."},{"key":"8595_CR18","doi-asserted-by":"publisher","first-page":"126283","DOI":"10.1016\/j.ijbiomac.2023.126283","volume":"251","author":"Y Wang","year":"2023","unstructured":"Wang Y, Xu J, Yu C, Zhou X, Chang L, Liu J, Peng Q. Prevention of bacterial biofilm formation on orthodontic brackets by non-crosslinked chitosan coating. Int J Biol Macromol. 2023;251:126283.","journal-title":"Int J Biol Macromol"},{"issue":"2","key":"8595_CR19","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/S0889-5406(95)70075-7","volume":"108","author":"C Matasa","year":"1995","unstructured":"Matasa C. Microbial attack of orthodontic adhesives. Am J Orthod Dentofac Orthop. 1995;108(2):132\u201341.","journal-title":"Am J Orthod Dentofac Orthop"},{"issue":"2024","key":"8595_CR20","first-page":"241","volume":"26","author":"ME Helou","year":"2024","unstructured":"Helou ME, Chakar S, Nicolas E, Estephan E, Cuisinier F, Barth\u00e9lemi S. Can orthodontic adhesive systems inhibit the formation and development of white spot lesions during fixed orthodontic treatment? a systematic review. J Adhes Dent. 2024;26(2024):241\u201352.","journal-title":"J Adhes Dent"},{"issue":"19","key":"8595_CR21","doi-asserted-by":"publisher","first-page":"4280","DOI":"10.3390\/ma13194280","volume":"13","author":"O Cicek","year":"2020","unstructured":"Cicek O, Ozkalayci N, Yetmez M. Mean shearing stroke frequency of orthodontic brackets under cycling loading: an in vitro study. Materials. 2020;13(19):4280.","journal-title":"Materials"},{"issue":"2","key":"8595_CR22","doi-asserted-by":"publisher","first-page":"724","DOI":"10.3390\/ma16020724","volume":"16","author":"I Eser","year":"2023","unstructured":"Eser I, Cicek O, Ozkalayci N, Yetmez M, Erener H. Effect of different types of adhesive agents on orthodontic bracket shear bond strength: A cyclic loading study. Materials. 2023;16(2):724.","journal-title":"Materials"},{"issue":"4","key":"8595_CR23","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1016\/j.ajodo.2010.09.030","volume":"140","author":"NF Talic","year":"2011","unstructured":"Talic NF. Effect of fluoridated paste on the failure rate of precoated brackets bonded with self-etching primer: a prospective split-mouth study. Am J Orthod Dentofac Orthop. 2011;140(4):527\u201330.","journal-title":"Am J Orthod Dentofac Orthop"},{"issue":"1","key":"8595_CR24","doi-asserted-by":"publisher","first-page":"27","DOI":"10.59566\/IJBS.2011.7027","volume":"7","author":"AP Hudson","year":"2011","unstructured":"Hudson AP, Grobler SR, Harris AM. Orthodontic molar brackets: the effect of three different base designs on shear bond strength. Int J Biomed Sci. 2011;7(1):27\u201334.","journal-title":"Int J Biomed Sci"},{"issue":"1","key":"8595_CR25","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1186\/s12903-025-05515-3","volume":"25","author":"G Kazlauskait\u0117","year":"2025","unstructured":"Kazlauskait\u0117 G, Vaitiek\u016bnas R, Lopatien\u0117 K, Jutas A, Palesik B, Smailien\u0117 D. The impact of temperature on the shear bond strength of conventional multi-step and self-adhesive orthodontic adhesive systems: an in-vitro study. BMC Oral Health. 2025;25(1):189.","journal-title":"BMC Oral Health"},{"key":"8595_CR26","doi-asserted-by":"publisher","unstructured":"Joseph R, Ahmed N, Bhat KRR. Evaluation of shear bond strength of a primer incorporated orthodontic composite resin: an in-vitro study. Cureus. 2022;14(4):e24088. https:\/\/doi.org\/10.7759\/cureus.24088.","DOI":"10.7759\/cureus.24088"},{"key":"8595_CR27","unstructured":"RM D. Evaluation of the effect of different types of adhesive agents on enamel demineralization in artificial cariogenic suspension. Specialty Thesis Zonguldak, T\u00fcrkiye: Zonguldak B\u00fclent Ecevit University; 2022."},{"issue":"2","key":"8595_CR28","doi-asserted-by":"publisher","first-page":"401","DOI":"10.3390\/coatings13020401","volume":"13","author":"RM Demircioglu","year":"2023","unstructured":"Demircioglu RM, Cicek O, Comert F, Erener H. Do different types of adhesive agents effect enamel demineralization for orthodontic bonding? an in vitro study. Coatings. 2023;13(2):401.","journal-title":"Coatings"},{"issue":"5","key":"8595_CR29","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1016\/j.ajodo.2019.05.011","volume":"156","author":"CI Theodorou","year":"2019","unstructured":"Theodorou CI, Kuijpers-Jagtman AM, Bronkhorst EM, Wagener FA. Optimal force magnitude for bodily orthodontic tooth movement with fixed appliances: a systematic review. Am J Orthod Dentofac Orthop. 2019;156(5):582\u201392.","journal-title":"Am J Orthod Dentofac Orthop"},{"key":"8595_CR30","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1590\/S2176-94512010000100010","volume":"15","author":"MM Farret","year":"2010","unstructured":"Farret MM, Gon\u00e7alves TS, Lima EMSd M, LMd, Oshima HMS, Kochenborger R, Freitas MPM. The influence of the methodological variables on the shear bond strength. Dent Press J Orthod. 2010;15:80\u20138.","journal-title":"Dent Press J Orthod"},{"issue":"3","key":"8595_CR31","doi-asserted-by":"publisher","first-page":"984","DOI":"10.3390\/ma16030984","volume":"16","author":"M Toz Ertop","year":"2023","unstructured":"Toz Ertop M, Cicek O, Erener H, Ozkalayci N, Demir Cicek B, Comert F. Evaluation of the demineralization development around different types of orthodontic brackets. Materials. 2023;16(3):984.","journal-title":"Materials"},{"issue":"6","key":"8595_CR32","doi-asserted-by":"publisher","first-page":"2136","DOI":"10.3390\/jcm15062136","volume":"15","author":"T Aydo\u011fan","year":"2026","unstructured":"Aydo\u011fan T, Cicek O, Yetmez M. Effect of Demineralization on Fatigue-Based Shear Bond Strength Across Different Orthodontic Brackets: An In Vitro Study. J Clin Med. 2026;15(6):2136.","journal-title":"J Clin Med"},{"issue":"1","key":"8595_CR33","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.sjdr.2014.08.001","volume":"6","author":"AK Rai","year":"2015","unstructured":"Rai AK. Evaluation of bracket failure rate in orthodontic patients bonded with and without primer. Saudi J Dent Res. 2015;6(1):48\u201353.","journal-title":"Saudi J Dent Res"},{"issue":"2","key":"8595_CR34","doi-asserted-by":"publisher","first-page":"105","DOI":"10.4103\/jispcd.jispcd_44_23","volume":"14","author":"A Kumar","year":"2024","unstructured":"Kumar A, Jain R, Aravind T. In vivo comparative assessment of bracket bond failure rates of single-component adhesives. J Int Soc Prev Community Dent. 2024;14(2):105\u201311.","journal-title":"J Int Soc Prev Community Dent"},{"key":"8595_CR35","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1093\/ejo\/cjac050","volume":"45","author":"C Dud\u00e1s","year":"2022","unstructured":"Dud\u00e1s C, Czumbel L, Kiss S, Gede N, Hegyi P, M\u00e1rtha K, Varga G. Clinical bracket failure rates between different bonding techniques: a systematic review and meta-analysis. Eur J Orthod. 2022;45:175\u201385.","journal-title":"Eur J Orthod"},{"issue":"2","key":"8595_CR36","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/j.ortho.2021.03.001","volume":"19","author":"P Daneshkazemi","year":"2021","unstructured":"Daneshkazemi P, Sadeghian S, Khodaei M. Shear bond strength of orthodontic brackets on intact and demineralized enamel after application of resin infiltrant, fluoride varnish and casein phosphopeptide-amorphous calcium phosphate remineralizing agents: in-vitro study. Int Orthod. 2021;19(2):259\u201368.","journal-title":"Int Orthod"},{"key":"8595_CR37","doi-asserted-by":"publisher","first-page":"1598515","DOI":"10.3389\/fmats.2025.1598515","volume":"12","author":"N Almosa","year":"2025","unstructured":"Almosa N, Alsaleh A, Alnowaiser A, Alhogail N, Alsuliman A, Alswailem L, Zawawi R, Habib SR. Assessment of enamel demineralization, shear bond strength, and failure mode following the use of orthodontic adhesive containing silver nanoparticles: an in-vitro study. Front Mater. 2025;12:1598515.","journal-title":"Front Mater"},{"issue":"01","key":"8595_CR38","doi-asserted-by":"publisher","first-page":"452","DOI":"10.53350\/pjmhs2023171452","volume":"17","author":"Q Khalid","year":"2023","unstructured":"Khalid Q, Rahbar MI, Chaudhry NA, Riaz A, Aziz A, Ata S. Comparison of shear bond strength of orthodontic brackets with fifth and eighth generation adhesive systems. Pak J Med Health Sci. 2023;17(01):452.","journal-title":"Pak J Med Health Sci"},{"key":"8595_CR39","volume-title":"Orthodontic applications of biomaterials: a clinical guide","author":"T Eliades","year":"2016","unstructured":"Eliades T, Brantley WA. Orthodontic applications of biomaterials: a clinical guide. Cambridge, UK: Woodhead Publishing; 2016."},{"key":"8595_CR40","doi-asserted-by":"publisher","unstructured":"Selvaraj M, Mohaideen K, Sennimalai K, Gothankar GS, Arora G. Effect of oral environment on contemporary orthodontic materials and its clinical implications. J Orthod Sci. 2023;12(1). https:\/\/doi.org\/10.4103\/jos.jos_73_22.","DOI":"10.4103\/jos.jos_73_22"},{"issue":"1","key":"8595_CR41","doi-asserted-by":"publisher","first-page":"7","DOI":"10.18231\/j.jco.2025.003","volume":"9","author":"AK Subramanian","year":"2025","unstructured":"Subramanian AK, Marrapodi MM, Ronsivalle V, Uzunc\u0131buk H, Russo D, Cicci\u00f9 M, Minervini G. Comparative analysis of orthodontic adhesives for bracket bonding reliability: A systematic review. J Contemp Orthod. 2025;9(1):7\u201320.","journal-title":"J Contemp Orthod"},{"issue":"3","key":"8595_CR42","doi-asserted-by":"publisher","first-page":"2353","DOI":"10.4103\/jpbs.jpbs_303_24","volume":"16","author":"S Chandra","year":"2024","unstructured":"Chandra S, Jha A, Asiri S, Naik A, Sharma S, Nair A, Manek P. Effect of fixed orthodontic appliances on oral microbial changes and dental caries risk in children: a 6-Month prospective study. J Pharm Bioallied Sci. 2024;16(3):2353\u20135.","journal-title":"J Pharm Bioallied Sci"},{"key":"8595_CR43","doi-asserted-by":"publisher","first-page":"780","DOI":"10.3390\/jcm10040780","volume":"10","author":"M Contaldo","year":"2021","unstructured":"Contaldo M, Lucchese A, Lajolo C, Rupe C, Di Stasio D, Romano A, Petruzzi M, Serpico R. The oral microbiota changes in orthodontic patients and effects on oral health: An overview. J Clin Med. 2021;10:780.","journal-title":"J Clin Med"},{"issue":"5","key":"8595_CR44","doi-asserted-by":"publisher","first-page":"531","DOI":"10.2319\/111422-781.1","volume":"93","author":"OGA Horan","year":"2023","unstructured":"Horan OGA, Al-Khateeb SN. Comparison of three orthodontic bonding systems in white spot lesion development: a randomized clinical trial. Angle Orthod. 2023;93(5):531\u20137.","journal-title":"Angle Orthod"},{"key":"8595_CR45","first-page":"18","volume":"2","author":"S Narendran","year":"2019","unstructured":"Narendran S, Raghunath N. Comparison of enamel demineralization around orthodontic brackets bonded with conventional etching, self-etch primer and antimicrobial monomer containing self-etch primer. Int J Adv Res Innov Ideas Educ. 2019;2:18\u201322.","journal-title":"Int J Adv Res Innov Ideas Educ"},{"issue":"3","key":"8595_CR46","doi-asserted-by":"publisher","first-page":"94","DOI":"10.18231\/j.jco.2022.018","volume":"6","author":"S Rai","year":"2022","unstructured":"Rai S, Prasad RR, Jain AK, Sahu A, Lall R, Thakur S. A comparative study of shear bond strength of four different light cure orthodontic adhesives: An in vitro study. J Contemp Orthod. 2022;6(3):94\u20139.","journal-title":"J Contemp Orthod"},{"key":"8595_CR47","doi-asserted-by":"publisher","first-page":"1442","DOI":"10.12688\/f1000research.141328.1","volume":"12","author":"S Tallani","year":"2023","unstructured":"Tallani S, Singla R, Singla N, Natarajan M, Kukkila J. Clinical performance of light-cured orthodontic adhesives for bonding brackets: An in-vitro study. F1000Res. 2023;12:1442.","journal-title":"F1000Res"},{"issue":"6","key":"8595_CR48","doi-asserted-by":"publisher","first-page":"2991","DOI":"10.52711\/0974-360X.2023.00494","volume":"16","author":"R Rizka Firdaus","year":"2023","unstructured":"Rizka Firdaus R, Ratna Nurlia A, Ida Bagus N. A: Comparison between shear strength in total etch and self etch adhesive material in bonding of stainless-steel brackets. Res J Pharm Technol. 2023;16(6):2991\u20138.","journal-title":"Res J Pharm Technol"},{"issue":"2","key":"8595_CR49","first-page":"000293","volume":"6","author":"A Kamboj","year":"2021","unstructured":"Kamboj A, Chopra SS, Bali A, Sharma A, Lakhani P, Singh S. Changes in enamel topography with the contemporary orthodontic adhesives: A pilot study. J Dent Sci. 2021;6(2):000293.","journal-title":"J Dent Sci"},{"issue":"2","key":"8595_CR50","doi-asserted-by":"publisher","first-page":"974","DOI":"10.4103\/jpbs.jpbs_261_23","volume":"15","author":"D Singh","year":"2023","unstructured":"Singh D, Swarup D, Kumari N, Kumar S, Priya T, Sinha R. In vitro evaluation of shear bond strength of orthodontic brackets bonded with different adhesives. J Pharm Bioallied Sci. 2023;15(2):974\u20136.","journal-title":"J Pharm Bioallied Sci"},{"issue":"7","key":"8595_CR51","first-page":"53","volume":"7","author":"C Yadala","year":"2015","unstructured":"Yadala C, Gaddam R, Arya S, Baburamreddy K, Raju VR, Varma PK. Comparison of shear bond strength of three self-etching adhesives: an in-vitro study. J Int Oral Health. 2015;7(7):53.","journal-title":"J Int Oral Health"},{"issue":"5","key":"8595_CR52","doi-asserted-by":"publisher","first-page":"1252","DOI":"10.3390\/biomedicines11051252","volume":"11","author":"V Perkovi\u0107","year":"2023","unstructured":"Perkovi\u0107 V, Ani\u010di\u0107 M\u0160, Lughi V, Pozzan L, Me\u0161trovi\u0107 S, Turco G. Correlation of shear bond strength and degree of conversion in conventional and self-adhesive systems used in orthodontic bonding procedures. Biomedicines. 2023;11(5):1252.","journal-title":"Biomedicines"},{"issue":"6","key":"8595_CR53","doi-asserted-by":"publisher","first-page":"3987","DOI":"10.1007\/s00784-020-03729-z","volume":"25","author":"U Ok","year":"2021","unstructured":"Ok U, Aksakalli S, Eren E, Kechagia N. Single-component orthodontic adhesives: comparison of the clinical and in vitro performance. Clin Oral Investig. 2021;25(6):3987\u201399.","journal-title":"Clin Oral Investig"},{"key":"8595_CR54","doi-asserted-by":"publisher","DOI":"10.1007\/s00056-025-00612-y","author":"M El Helou","year":"2025","unstructured":"El Helou M, Canamas E, Nicolas E, Gravier A, Estephan E, Cuisinier F, Barthelemi S. Comparative in vitro study of bond strength of two-step orthodontic bonding systems. Fortschr der Kieferorthop\u00e4die\/Journal Orofac Orthop. 2025. https:\/\/doi.org\/10.1007\/s00056-025-00612-y.","journal-title":"Fortschr der Kieferorthop\u00e4die\/Journal Orofac Orthop"},{"issue":"2","key":"8595_CR55","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1016\/j.ortho.2020.01.010","volume":"18","author":"HB Bilen","year":"2020","unstructured":"Bilen HB, \u00c7okako\u011flu S. Effects of one-step orthodontic adhesive on microleakage and bracket bond strength: An in vitro comparative study. Int Orthod. 2020;18(2):366\u201373.","journal-title":"Int Orthod"},{"issue":"14","key":"8595_CR56","doi-asserted-by":"publisher","first-page":"4892","DOI":"10.3390\/jcm14144892","volume":"14","author":"F Uslu","year":"2025","unstructured":"Uslu F, Gunes TE, Akin M, Akman H. A Comparison of the Effectiveness of Combined Primer and Adhesive Systems in Orthodontic Bonding: An In Vitro Study. J Clin Med. 2025;14(14):4892.","journal-title":"J Clin Med"},{"key":"8595_CR57","unstructured":"Tur\u011fut A. Clinical evaluation of one-step orthodontic adhesive without primer for bonding of metal brackets in terms of white spot lesion formation and bond strength. Specialty Thesis Denizli, T\u00fcrkiye: Pamukkale University; 2020."},{"issue":"5","key":"8595_CR58","doi-asserted-by":"publisher","first-page":"766","DOI":"10.2319\/120816-880.1","volume":"87","author":"SM Wilson","year":"2017","unstructured":"Wilson SM, Lien W, Lee DP, Dunn WJ. Confocal microscope analysis of depth of etch between self-limiting and traditional etchant systems. Angle Orthod. 2017;87(5):766\u201373.","journal-title":"Angle Orthod"},{"issue":"7","key":"8595_CR59","doi-asserted-by":"publisher","first-page":"2567","DOI":"10.1002\/jemt.24111","volume":"85","author":"J Rodr\u00edguez-Ch\u00e1vez","year":"2022","unstructured":"Rodr\u00edguez-Ch\u00e1vez J, Arenas-Alatorre J, Flores-Ruiz H, Aguilar-P\u00e9rez F, Flores-Ledesma A, Moreno-Vargas Y, Pesqueira-Melgarejo R. Correlation between dental enamel chemical composition and bracket debonding, comparing adhesive systems through a scanning electron microscope. Microsc Res Tech. 2022;85(7):2567\u201378.","journal-title":"Microsc Res Tech"},{"issue":"2","key":"8595_CR60","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1111\/ocr.12602","volume":"26","author":"D Alvarez","year":"2023","unstructured":"Alvarez D, Barmak AB, Rossouw PE, Michelogiannakis D. Comparison of shear bond strength of orthodontic brackets bonded to human teeth with and without fluorotic enamel: A systematic review and meta-analysis of experimental in vitro studies. Orthod Craniofac Res. 2023;26(2):141\u201350.","journal-title":"Orthod Craniofac Res"}],"container-title":["BMC Oral Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12903-026-08595-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12903-026-08595-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12903-026-08595-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T02:01:51Z","timestamp":1784858511000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12903-026-08595-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,18]]},"references-count":60,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["8595"],"URL":"https:\/\/doi.org\/10.1186\/s12903-026-08595-x","relation":{},"ISSN":["1472-6831"],"issn-type":[{"value":"1472-6831","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,18]]},"assertion":[{"value":"27 January 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This study was conducted in accordance with the Declaration of Helsinki and was approved by the Zonguldak B\u00fclent Ecevit University Non-Interventional Clinical Research Ethics Committee (approval date: 31 May 2023; approval no: 2023\/11\u201314). Written informed consent for orthodontic treatment was obtained from all patients prior to treatment initiation. As the study involved anonymized extracted teeth collected as part of routine clinical care, no additional informed consent was required for the purposes of this study.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"1343"}}