{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T02:52:01Z","timestamp":1781578321572,"version":"3.54.5"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T00:00:00Z","timestamp":1781568000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T00:00:00Z","timestamp":1781568000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100009827","name":"Alexandria University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100009827","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Oral Health"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to investigate whether the integration of functionalized carbon nanotubes (CNTs) with hydroxyapatite (HA) could create a bioactive nanocomposite capable of enhancing the early stages of osseointegration. Specifically, we investigated whether the high surface area and nanoscale structure of CNTs, combined with the osteoconductivity of 1% HA, could significantly enhance bone-to-implant contact (BIC) and new bone area (NBA) compared to traditional titanium surfaces in a mandibular model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Here we evaluated the osseointegration of titanium implant discs coated with CNTs and CNTs combined with 1% HA in a rabbit mandibular model. Thirty rabbits received uncoated, CNT-coated, or CNT- HA coated titanium discs implanted into mandibular defects. After 4 weeks, bone-to-implant contact (BIC) and new bone area (NBA) were assessed histomorphometrically.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Both CNT and CNT- HA coatings significantly increased BIC and NBA compared to uncoated implants (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05), with no significant difference between coated groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>CNT-based coatings enhance early osseointegration of titanium implants, while the addition of 1% HA does not confer additional benefit within 4 weeks, suggesting CNT coatings alone may improve implant integration effectively.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12903-026-08811-8","type":"journal-article","created":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T01:45:28Z","timestamp":1781574328000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Carbon nanotube\u2011 and hydroxyapatite\u2011coated implants: histomorphometric assessment in a rabbit model"],"prefix":"10.1186","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2675-5039","authenticated-orcid":false,"given":"Amira S.","family":"Eissa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haitham Mohammed Abou","family":"Eleneen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-7137-4230","authenticated-orcid":false,"given":"Aya S.","family":"Sedik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,16]]},"reference":[{"key":"8811_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.mser.2014.10.001","volume":"87","author":"Q Chen","year":"2015","unstructured":"Chen Q, Thouas GA. 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