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All procedures were conducted in accordance with the ethical standards of the 1964 Declaration of Helsinki and its subsequent amendments. All participants provided written informed consent prior to enrolment. Before providing consent, they received comprehensive information about the study objectives, procedures, potential risks and benefits, and were informed that they could withdraw from the study at any time without affecting their routine care.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"1823"}}