{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T10:30:07Z","timestamp":1758709807341},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2015,4,17]],"date-time":"2015-04-17T00:00:00Z","timestamp":1429228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Women's Health"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1186\/s12905-015-0191-4","type":"journal-article","created":{"date-parts":[[2015,4,15]],"date-time":"2015-04-15T23:02:23Z","timestamp":1429138943000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["5-Aminolevulinic-acid-based fluorescence spectroscopy and conventional colposcopy for in vivo detection of cervical pre-malignancy"],"prefix":"10.1186","volume":"15","author":[{"given":"Rasa","family":"Vansevi\u010di\u016bt\u0117","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonas","family":"Venius","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga","family":"\u017dukovskaja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daiva","family":"Kanopien\u0117","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simona","family":"Letautien\u0117","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ri\u010dardas","family":"Rotomskis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,4,17]]},"reference":[{"key":"191_CR1","doi-asserted-by":"publisher","first-page":"2893","DOI":"10.1002\/ijc.25516","volume":"127","author":"J Ferlay","year":"2010","unstructured":"Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010;127:2893\u2013917.","journal-title":"Int J Cancer"},{"issue":"3","key":"191_CR2","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1093\/annonc\/mdp471","volume":"21","author":"M Arbyn","year":"2010","unstructured":"Arbyn M, Anttila A, Jordan J, Ronco G, Schenck U, Segnan N, et al. European guidelines for quality assurance in cervical cancer screening. Second edition\u2014summary document. Ann Oncol. 2010;21(3):448\u201358.","journal-title":"Ann Oncol"},{"key":"191_CR3","unstructured":"Lithuanian Cancer Registry Available from: http:\/\/www.nvi.lt\/index.php?-1413089819 ."},{"key":"191_CR4","doi-asserted-by":"publisher","first-page":"1899","DOI":"10.1002\/ijc.25525","volume":"128","author":"M Arbyn","year":"2011","unstructured":"Arbyn M, Antoine J, Magi M, Smailyte G, Stengrevics A, Suteu O, et al. Trends in cervical cancer incidence and mortality in the Baltic countries. Bulgaria and Romania Int J Cancer. 2011;128:1899\u2013907.","journal-title":"Bulgaria and Romania Int J Cancer"},{"issue":"3","key":"191_CR5","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1002\/ijc.28605","volume":"135","author":"CM Wheeler","year":"2014","unstructured":"Wheeler CM, Hunt WC, Cuzick J, Langsfeld E, Robertson M, Castle PE. New Mexico HPV Pap registry steering committee the influence of type-specific human papillomavirus infections on the detection of cervical precancer and cancer: a population-based study of opportunistic cervical screening in the united states. Int J Cancer. 2014;135(3):624\u201334.","journal-title":"Int J Cancer"},{"key":"191_CR6","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1111\/j.1601-0825.2005.01127.x","volume":"11","author":"S Nair","year":"2005","unstructured":"Nair S, Pillai MR. Human papillomavirus and disease mechanisms: relevance to oral and cervical cancers. Oral Dis. 2005;11:350\u20139.","journal-title":"Oral Dis"},{"key":"191_CR7","unstructured":"Singer A, Monaghan MJ, Quek SC. Lower Genital Tract Precancer. Colposcopy, pathology and treatment. 2nd ed. Oxford. Blacwell science; 2008."},{"key":"191_CR8","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1016\/j.bpobgyn.2011.05.005","volume":"25","author":"JHJ Tan","year":"2011","unstructured":"Tan JHJ, Wrede CDH. New technologies and advances in colposcopic assessment. Best Practice & Research Clinical Obstetrics and Gynaecology. 2011;25:667\u201377.","journal-title":"Best Practice & Research Clinical Obstetrics and Gynaecology"},{"issue":"6","key":"191_CR9","doi-asserted-by":"publisher","first-page":"1209","DOI":"10.1097\/AOG.0b013e318293ab22","volume":"121","author":"RP Bosgraaf","year":"2013","unstructured":"Bosgraaf RP, Mast PP, Struik-van der Zanden PH, Bulten J, Massuger LF, Bekkers RL. Overtreatment in a see-and-treat approach to cervical intraepithelial lesions. Obstet Gynecol. 2013;121(6):1209\u201316.","journal-title":"Obstet Gynecol"},{"issue":"7","key":"191_CR10","first-page":"1723","volume":"12","author":"A Aue-Aungkul","year":"2011","unstructured":"Aue-Aungkul A, Punyawatanasin S, Natprathan A, Srisomboon J, Kietpeerakool C. \"See and treat\" approach is appropriate in women with high-grade lesions on either cervical cytology or colposcopy. Asian Pac J Cancer Prev. 2011;12(7):1723\u20136.","journal-title":"Asian Pac J Cancer Prev"},{"key":"191_CR11","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1309\/EWYGWFRRM8798U5P","volume":"129","author":"PD Palma","year":"2008","unstructured":"Palma PD, Rossi PG, Collina G, Buccoliero AM, Ghiringhello B, Lestani M, et al. The NTCC pathology group the risk of false-positive histology according to the reason for colposcopy referral in cervical cancer screening. Am J Clin Pathol. 2008;129:75\u201380.","journal-title":"Am J Clin Pathol"},{"issue":"1","key":"191_CR12","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1097\/LGT.0b013e3181a02058","volume":"14","author":"ML Cremer","year":"2010","unstructured":"Cremer ML, Peralta EI, Dheming SG, Jimenez ME, Davis-Dao CA, Alonzo TA, et al. Digital assessment of the reproductive tract versus colposcopy for directing biopsies in women with abnormal Pap smears. Journal of Lower Genital Tract Disease. 2010;14(1):5\u201310.","journal-title":"Journal of Lower Genital Tract Disease"},{"issue":"4","key":"191_CR13","doi-asserted-by":"publisher","first-page":"1331","DOI":"10.1016\/j.ajog.2005.05.008","volume":"193","author":"RS Guido","year":"2005","unstructured":"Guido RS, Jeronimo J, Schiffman M, Solomon D. ALTS Group The distribution of neoplasia arising on the cervix: results from the ALTS trial. Am J Obstet Gynecol. 2005;193(4):1331\u20137.","journal-title":"Am J Obstet Gynecol"},{"issue":"9","key":"191_CR14","doi-asserted-by":"publisher","first-page":"744","DOI":"10.1016\/S1542-3565(04)00345-3","volume":"2","author":"TD Wang","year":"2004","unstructured":"Wang TD, Van Dam J. Optical biopsy: a new frontier in endoscopic detection and diagnosis. Clin Gastroenterol Hepatol. 2004;2(9):744\u201353.","journal-title":"Clin Gastroenterol Hepatol"},{"key":"191_CR15","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1177\/153303461101000601","volume":"10","author":"RR Alfano","year":"2011","unstructured":"Alfano RR. Advances in optical biopsy for cancer diagnosis. Technol Cancer Res Treat. 2011;10:101.","journal-title":"Technol Cancer Res Treat"},{"issue":"10","key":"191_CR16","doi-asserted-by":"publisher","first-page":"104020","DOI":"10.1088\/0957-0233\/20\/10\/104020","volume":"20","author":"B Costas","year":"2009","unstructured":"Costas B. Review of biomedical optical imaging\u2014a powerful, non-invasive, non-ionizing technology for improving in vivo diagnosis. Meas Sci Technol. 2009;20(10):104020.","journal-title":"Meas Sci Technol"},{"issue":"4","key":"191_CR17","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.mla.2008.08.002","volume":"23","author":"A Johansson","year":"2008","unstructured":"Johansson A, Kromer K, Sroka R, Stepp H. Clinical optical diagnostics: Status and perspectives. Medical Laser Application. 2008;23(4):155\u201374.","journal-title":"Medical Laser Application"},{"key":"191_CR18","volume-title":"Optin\u0117s diagnostikos technologijos (optin\u0117 biopsija) (Optical diagnostics technologies (optical biopsy))","author":"R Rotomskis","year":"2008","unstructured":"Rotomskis R, Streckyt\u0117 G, Bagdonas S, Venius J. Optin\u0117s diagnostikos technologijos (optin\u0117 biopsija) (Optical diagnostics technologies (optical biopsy)). Vilnius: Vilnius University press; 2008."},{"issue":"1","key":"191_CR19","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.copbio.2009.02.004","volume":"20","author":"JQ Brown","year":"2009","unstructured":"Brown JQ, Vishwanath K, Palmer GM, Ramanujam N. Advances in quantitative UV-visible spectroscopy for clinical and pre-clinical application in cancer. Curr Opin Biotechnol. 2009;20(1):119\u201331.","journal-title":"Curr Opin Biotechnol"},{"issue":"4","key":"191_CR20","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1593\/neo.81386","volume":"11","author":"VT Chang","year":"2009","unstructured":"Chang VT, Cartwright PS, Bean SM, Palmer GM, Bentley RC, Ramanujam N. Quantitative physiology of the precancerous cervix in vivo through optical spectroscopy. Neoplasia. 2009;11(4):325\u201332.","journal-title":"Neoplasia"},{"issue":"12","key":"191_CR21","first-page":"1219","volume":"40","author":"R Rotomskis","year":"2004","unstructured":"Rotomskis R, Streckyt\u0117 G. Fluorescencin\u0117 navik\u0173 diagnostika. (Fluorescence diagnostics of tumors.). Medicina. 2004;40(12):1219\u201330.","journal-title":"Medicina"},{"issue":"1","key":"191_CR22","doi-asserted-by":"publisher","first-page":"50","DOI":"10.5306\/wjco.v2.i1.50","volume":"2","author":"L Quan","year":"2011","unstructured":"Quan L. Role of optical spectroscopy using endogenous contrasts in clinical cancer diagnosis. World J Clin Oncol. 2011;2(1):50\u201363.","journal-title":"World J Clin Oncol"},{"key":"191_CR23","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1039\/b305410a","volume":"126","author":"K Badizadegan","year":"2004","unstructured":"Badizadegan K, Backman V, Boone CW, Crum CP, Dasari RR, Georgakoudi I, et al. Spectroscopic diagnosis and imaging of invisible pre-cancer. Faraday Discuss. 2004;126:265\u201379.","journal-title":"Faraday Discuss"},{"issue":"6","key":"191_CR24","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1016\/S0901-5027(00)80081-8","volume":"29","author":"MA Suhr","year":"2000","unstructured":"Suhr MA, Hopper C, Jones L, George JG, Bown SG, MacRobert AJ. Optical biopsy systems for the diagnosis and monitoring of superficial cancer and precancer. Int J Oral Maxillofac Surg. 2000;29(6):453\u20137.","journal-title":"Int J Oral Maxillofac Surg"},{"key":"191_CR25","doi-asserted-by":"crossref","unstructured":"Jerjes WK, Upile T, Wong BJ, Betz CS, Sterenborg HJ, Witjes MJ, Veen van R, Biel MA, El-Naggar AK, Mosse CA, Olivo M, Richards-Kortum R. The future of medical diagnostics: review paper. Head Neck Oncol. 2011; 3:38.","DOI":"10.1186\/1758-3284-3-38"},{"key":"191_CR26","first-page":"977","volume":"6","author":"A Siero\u0144","year":"2013","unstructured":"Siero\u0144 A, Siero\u0144-Sto\u0142tny K, Kawczyk-Krupka A, Latos W, Kwiatek S, Straszak D, et al. The role of fluorescence diagnosis in clinical practice. Onco Targets Ther. 2013;6:977\u201382.","journal-title":"Onco Targets Ther"},{"key":"191_CR27","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/j.pdpdt.2009.01.006","volume":"5","author":"K Moghissi","year":"2008","unstructured":"Moghissi K, Stringer MR, Dixon K. Fluorescence photodiagnosis in clinical practice. Photodiagnosis Photodyn Ther. 2008;5:235\u20137.","journal-title":"Photodiagnosis Photodyn Ther"},{"key":"191_CR28","doi-asserted-by":"publisher","first-page":"10193","DOI":"10.1073\/pnas.91.21.10193","volume":"91","author":"N Ramanujam","year":"1994","unstructured":"Ramanujam N, Mitchell MF, Mahadevan A, Thomsen S, Silva E, Richards-Kortum RR. In vivo diagnosis of cervical intraepithelial neoplasia using 337\u00a0nm laser induced fluorescence. Proc Natl Acad Sci. 1994;91:10193\u20137.","journal-title":"Proc Natl Acad Sci"},{"key":"191_CR29","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1002\/(SICI)1096-9101(1996)19:1<63::AID-LSM8>3.0.CO;2-O","volume":"19","author":"N Ramanujam","year":"1996","unstructured":"Ramanujam N, Mitchell MF, Mahadevan A, Thomsen S, Malpica A, Wright T, et al. Spectroscopic diagnosis of cervical intraepithelial neoplasia (CIN cpb using laser induced fluorescence spectra at multiple excitation wavelenghts). Lasers Surg Med. 1996;19:63\u201374.","journal-title":"Lasers Surg Med"},{"issue":"2","key":"191_CR30","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1016\/S1368-8375(02)00036-2","volume":"39","author":"K Onizawa","year":"2003","unstructured":"Onizawa K, Okamura N, Saginoya H, Yoshida H. Characterization of autofluorescence in oral squamous cell carcinoma. Oral Oncol. 2003;39(2):150\u20136.","journal-title":"Oral Oncol"},{"issue":"4","key":"191_CR31","first-page":"763","volume":"21","author":"W Zheng","year":"2002","unstructured":"Zheng W, Soo KC, Sivanandan R, Olivo M. Detection of neoplasms in the oral cavity by digitized endoscopic imaging of 5-aminolevulinic acid-induced protoporphyrin IX fluorescence. Int J Oncol. 2002;21(4):763\u20138.","journal-title":"Int J Oncol"},{"issue":"10","key":"191_CR32","doi-asserted-by":"publisher","first-page":"2275","DOI":"10.1002\/(SICI)1097-0142(20000515)88:10<2275::AID-CNCR11>3.0.CO;2-B","volume":"88","author":"P Hillemanns","year":"2000","unstructured":"Hillemanns P, Weingandt H, Baumgartner R, Diebold J, Xiang W, Stepp H. Photodetection of cervical intraepithelial neoplasia using 5-aminolevulinic acid-induced porphyrin fluorescence. Cancer. 2000;88(10):2275\u201382.","journal-title":"Cancer"},{"issue":"2","key":"191_CR33","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/j.pdpdt.2006.10.003","volume":"4","author":"P Collinet","year":"2007","unstructured":"Collinet P, Jouve E, Regis C, Farine MO, Vinatier D, Cosson M, et al. Fluorescence diagnosis of cervical squamous intraepithelial lesions: A clinical feasibility study. Photodiagn Photodyn Ther. 2007;4(2):112\u20136.","journal-title":"Photodiagn Photodyn Ther"},{"issue":"2","key":"191_CR34","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1117\/1.1463045","volume":"7","author":"A Bogaards","year":"2002","unstructured":"Bogaards A, Aalders MC, Zeyl CC, de Blok S, Dannecker C, Hillemanns P, et al. Localization and staging of cervical intraepithelial neoplasia using double ratio fluorescence imaging. J Biomed Opt. 2002;7(2):215\u201320.","journal-title":"J Biomed Opt"},{"key":"191_CR35","unstructured":"Vansevi\u010di\u016bt\u0117 R, \u017dukovskaja O, Venius J. Comparison of 5-aminolevulinic acid based fluorescence diagnostics with histology in the detection of cervical neoplasia. Medical Physics in the Baltic States: proceedings of the 11th international conference on medical physics. 2013; 11:12-4."},{"key":"191_CR36","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1562\/0031-8655(2000)071<0730:APISTC>2.0.CO;2","volume":"71","author":"C Brookner","year":"2000","unstructured":"Brookner C, Follen M, Boiko I, Galvan J, Thomsen S, Malpica A, et al. Tissue slices autofluorescence patterns in fresh cervical tissue. Photochem Photobiol. 2000;71:730\u20136.","journal-title":"Photochem Photobiol"},{"key":"191_CR37","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1562\/0031-8655(2001)0730636AMOFCT2.0.CO2","volume":"73","author":"R Drezek","year":"2001","unstructured":"Drezek R, Brookner C, Pavlova I, Boiko I, Malpica A, Lotan R, et al. Autofluorescence microscopy of fresh cervical tissue sections reveals alterations in tissue biochemistry with dysplasia. Photochem Photobiol. 2001;73:636\u201341.","journal-title":"Photochem Photobiol"},{"key":"191_CR38","doi-asserted-by":"crossref","unstructured":"Richards-Kortum R, Drezek R, Basen-Enquist K, Cantor SB, Utzinger U, Brookner C, Follen M. Cervical dysplasia diagnosis with fluorescence spectroscopy. Handbook of biomedical fluorescence. CRC Press; 2003. p. 265-313.","DOI":"10.1201\/9780203912096-9"},{"key":"191_CR39","first-page":"83","volume":"29","author":"CM Florkowski","year":"2008","unstructured":"Florkowski CM. Sensitivity, specificity, receiver-operating characteristic (ROC) curves and likelihood ratios: communicating the performance of diagnostic tests. Clin Biochem Rev. 2008;29:83\u20137.","journal-title":"Clin Biochem Rev"},{"key":"191_CR40","first-page":"7","volume":"644","author":"AK Akobeng","year":"2007","unstructured":"Akobeng AK. Understanding diagnostic tests 3: receiver operating characteristic curves. Acta Pediatrica. 2007;644:7.","journal-title":"Acta Pediatrica"},{"issue":"12","key":"191_CR41","first-page":"1664","volume":"15","author":"VV Sapozhnikova","year":"2005","unstructured":"Sapozhnikova VV, Shakhova NM, Kamensky VA, Petrova SA, Snopova LB, Kuranov RV. Capabilities of fluorescence spectroscopy using 5-ALA and optical coherence tomography for diagnosis of neoplastic processes in the uterine cervix and vulva. Laser Phys. 2005;15(12):1664\u201373.","journal-title":"Laser Phys"}],"container-title":["BMC Women's Health"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12905-015-0191-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12905-015-0191-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12905-015-0191-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12905-015-0191-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,23]],"date-time":"2019-08-23T14:28:12Z","timestamp":1566570492000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcwomenshealth.biomedcentral.com\/articles\/10.1186\/s12905-015-0191-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,17]]},"references-count":41,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["191"],"URL":"https:\/\/doi.org\/10.1186\/s12905-015-0191-4","relation":{},"ISSN":["1472-6874"],"issn-type":[{"value":"1472-6874","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,17]]},"assertion":[{"value":"11 November 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 March 2015","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 April 2015","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"35"}}