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Likewise, during the study, all adverse events were registered and followed, fulfilling the maximum premise of safeguarding the safety of patients.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Dr. Santiago Palacios. Honoraria or consultation fees and participation in a company sponsored speakeaker\u2019s bureau: Bayer Healthcare, Bioiberica, Ferrer, Exeltis, Gedeon Richter, Gynea, MSD, Novo Nordisk, Pfizer, Procare Health Iberia S.L., Serelys, Servier, Shionogi, Teva. He also is a member of the editorial board of BMC Women\u2019s Health journal.Dr. Fernando Losa. Consultant in Spain Bayer, Procare Health Iberia S.L., E-Care You.Mrs. Eva M. Soler, Dr. Marieta Ramirez and Dr. Mariella Lilue declare no competing interests. Danial Khorsandi Ph.D. Principal researcher of the Procare Health Iberia S.L. and he has financial ties with Procare Health Iberia S.L.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"58"}}