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Some studies have recommended that an anti-M\u00fcllerian hormone (AMH) level greater than 3.8\u20135\u00a0ng\/mL can be used for diagnosing PCOS. This study aims to analyse serum AMH levels among PCOS women of reproductive age to use AMH as a biomarker predictor along with other Rotterdam criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this cross-sectional study, a total of 98 women visiting the fertility center of a private hospital in Lahore, Pakistan, were screened. Data were obtained from 51 PCOS newly diagnosed women aged 28.24\u00a0years (SD\u2009\u00b1\u20094.84\u00a0years) meeting at least two of the Rotterdam criteria and specific inclusion criteria. Baseline variables, menstrual cycle length, ovarian morphology on ultrasound, hirsutism, sex hormones, gonadotropin, and serum AMH levels were analysed during the follicular phase (1\u20135\u00a0days) of the menstrual cycle. Serum AMH was measured by an enzyme-linked immunosorbent assay.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A high serum AMH level (7.23\u2009\u00b1\u20094.67\u00a0ng\/ml) was recorded with normal sex hormone levels. Women with oligo-\/amenorrhea had a significant mean difference for luteinizing hormone (p\u2009=\u20090.02) and AMH levels (p\u2009=\u20090.03) when compared with women of normal menstrual cycle length. PCOS women with high AMH levels (\u2265\u20093.9\u00a0ng\/ml) showed a significant difference in ovarian morphology (p\u2009&lt;\u20090.05) when compared with the normal AMH group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>An elevated serum AMH level can be used as a strong predictor to reflect the certainty of PCOS diagnosis among women of reproductive age when study concurrently with the other Rotterdam criteria.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12905-022-01782-2","type":"journal-article","created":{"date-parts":[[2022,5,28]],"date-time":"2022-05-28T10:03:34Z","timestamp":1653732214000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Serum anti-M\u00fcllerian hormone as a predictor of polycystic ovarian syndrome among women of reproductive age"],"prefix":"10.1186","volume":"22","author":[{"given":"Muhammad Salman","family":"Butt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javeria","family":"Saleem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sobia","family":"Aiman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rubeena","family":"Zakar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iftikhar","family":"Sadique","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Fischer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,5,28]]},"reference":[{"issue":"6","key":"1782_CR1","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1046\/j.1365-2265.1999.00886.x","volume":"51","author":"KF Michelmore","year":"1999","unstructured":"Michelmore KF, Balen AH, Dunger DB, Vessey MP. 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All methods were performed in accordance with the Declaration of Helsinki. All the study participants\/their parents\/legal gradians provided informed consent before inclusion in the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests. FF serves on the Editorial Board of BMC Women\u2019s Health as Senior Board Member.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"199"}}