{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T04:19:29Z","timestamp":1772165969201,"version":"3.50.1"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T00:00:00Z","timestamp":1678406400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T00:00:00Z","timestamp":1678406400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Women's Health"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Delayed-onset postpartum preeclampsia (PET) is defined as a new diagnosis of preeclampsia presenting 48\u00a0h to 6\u00a0weeks postpartum. This disorder is infrequent and associated with a higher incidence of complications as compared to antepartum PET. There seems to be a need to further characterize this disorder. The aim of the study was to investigate the difference of maternal heart rate in women with delayed onset postpartum preeclampsia as compared to healthy controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The medical files of all women who were readmitted with delayed onset postpartum preeclampsia during 2014\u20132020 were reviewed. Data on maternal physiological characteristics were compared to healthy control group of women at the same post-partum day, with uncomplicated pregnancies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Included 45 women with the diagnosis of delayed onset of preeclampsia at 6.3\u2009\u00b1\u20092.86 post-partum day. As compared to controls (n\u2009=\u200949), women with delayed post-partum were older, 34.6\u2009\u00b1\u20095.4 vs. 32.3\u2009\u00b1\u20094.7\u00a0years,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003. There were no differences between groups regarding maternal gravidity, parity, BMI (kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ) or Hb level at delivery day. Women with delayed post-partum preeclampsia had lower mean pulse rate as compared to controls, 58\u2009\u00b1\u200915\u00a0bpm vs. 83\u2009\u00b1\u200911.6\u00a0bpm, respectively, P\u2009&lt;\u20090.0001. Only 17% of the women in the delayed onset group had pulse rate above 70\u00a0bpm as compared to 83% in the control group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Maternal low heart rate in cases with delayed onset of post-partum preeclampsia is an important clinical characteristic that may reflect baroreceptors response to maternal hypertension.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12905-023-02233-2","type":"journal-article","created":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T21:02:53Z","timestamp":1678395773000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Changes in maternal heart rate in delayed post-partum preeclampsia"],"prefix":"10.1186","volume":"23","author":[{"given":"Dorit","family":"Ravid","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michal","family":"Ovadia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aula","family":"Asali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shlomo","family":"Nisim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sivan Farladansky","family":"Gershnabel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tal","family":"Biron-Shental","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omer","family":"Weitzner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,3,10]]},"reference":[{"key":"2233_CR1","doi-asserted-by":"publisher","first-page":"338.e1","DOI":"10.1016\/j.ajog.2013.11.004","volume":"210","author":"CA Bigelow","year":"2014","unstructured":"Bigelow CA, Pereira GA, Warmsley A, et al. Risk factors for new-onset late postpartum preeclampsia in women without a history of preeclampsia. Am J Obstet Gynecol. 2014;210:338.e1-338.e8. https:\/\/doi.org\/10.1016\/j.ajog.2013.11.004.","journal-title":"Am J Obstet Gynecol"},{"key":"2233_CR2","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1097\/OGX.0000000000000424","volume":"72","author":"KJ Sharma","year":"2017","unstructured":"Sharma KJ, Kilpatrick SJ. Postpartum hypertension: etiology, diagnosis, and management. Obstet Gynecol Surv. 2017;72:248\u201352. https:\/\/doi.org\/10.1097\/OGX.0000000000000424.","journal-title":"Obstet Gynecol Surv"},{"key":"2233_CR3","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1097\/AOG.0000000000003099","volume":"133","author":"T Wen","year":"2019","unstructured":"Wen T, Wright JD, Goffman D, et al. Hypertensive postpartum admissions among women without a history of hypertension or preeclampsia. Obstet Gynecol. 2019;133:712\u20139. https:\/\/doi.org\/10.1097\/AOG.0000000000003099.","journal-title":"Obstet Gynecol"},{"key":"2233_CR4","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1097\/AOG.0000000000003508","volume":"134","author":"EK Redman","year":"2019","unstructured":"Redman EK, Hauspurg A, Hubel CA, et al. Clinical course, associated factors, and blood pressure profile of delayed-onset postpartum preeclampsia. Obstet Gynecol. 2019;134:995\u20131001. https:\/\/doi.org\/10.1097\/AOG.0000000000003508.","journal-title":"Obstet Gynecol"},{"key":"2233_CR5","doi-asserted-by":"publisher","first-page":"1102","DOI":"10.1097\/AOG.0b013e318231934c","volume":"118","author":"Z Al-Safi","year":"2011","unstructured":"Al-Safi Z, Imudia AN, Filetti LC, et al. Delayed postpartum preeclampsia and eclampsia: demographics, clinical course, and complications. Obstet Gynecol. 2011;118:1102\u20137. https:\/\/doi.org\/10.1097\/AOG.0b013e318231934c.","journal-title":"Obstet Gynecol"},{"key":"2233_CR6","doi-asserted-by":"publisher","first-page":"1627","DOI":"10.1152\/ajpheart.00966.2001","volume":"283","author":"LA Simmons","year":"2002","unstructured":"Simmons LA, Gillin AG, Jeremy RW. Structural and functional changes in left ventricle during normotensive and preeclamptic pregnancy. Am J Physiol - Hear Circ Physiol. 2002;283:1627\u201333. https:\/\/doi.org\/10.1152\/ajpheart.00966.2001.","journal-title":"Am J Physiol - Hear Circ Physiol"},{"key":"2233_CR7","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2016-217964","author":"A Hosokawa","year":"2017","unstructured":"Hosokawa A, Umazume T, Yamada T, Minakami H. Maternal bradycardia occurring prior to onset of HELLP syndrome in women with pre-eclampsia. 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All experimental protocols were approved by Meir Medical Center Human Investigation ethics Committee. All methods were carried out in accordance with relevant guidelines and regulations. Informed consent was not obtained from subjects due to the study nature.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"99"}}