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However, few studies focused on the interaction of obesity and sleep health on the female infertility risk. This study aimed to evaluate the combined impact of trouble sleeping \/ sleep duration and overweight\/obesity\/ abdominal obesity on the risk of female infertility.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>The data for this cross-sectional study was obtained from National Health and Nutritional Examination Survey, which provided information on trouble sleeping, sleep duration, overweight\/obesity, abdominal obesity, and confounding factors. Adopted weighted univariate and multivariate logistic regression models to explore the relationship between trouble sleeping, sleep duration, overweight\/obesity, abdominal obesity, and the risk of infertility, respectively, and the combined effect of trouble sleeping and overweight\/obesity, trouble sleeping and abdominal obesity, sleep duration and overweight\/obesity, sleep duration and abdominal obesity, on the female infertility risk.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>This study included a total of 1,577 women, and 191 were diagnosed with infertility. Women with infertility had a higher proportion of people with overweight\/obesity, abdominal obesity, sleep duration\u2009\u2264\u20097\u00a0h and trouble sleeping than those with non-infertility. The result indicated that trouble sleeping [odds ratio (OR)\u2009=\u20092.25, 95% confidence intervals (CI): 1.49\u20133.39], sleep duration\u2009\u2264\u20097\u00a0h (OR\u2009=\u20091.59, 95% CI: 1.03\u20132.48), and the combined impact of abdominal obesity and trouble sleeping (OR\u2009=\u20092.18, 95% CI: 1.28\u20133.72), abdominal obesity and sleep duration\u2009\u2264\u20097\u00a0h (OR\u2009=\u20092.00, 95% CI: 1.17\u20133.40), overweight\/obesity and trouble sleeping (OR\u2009=\u20092.29, 95% CI: 1.24\u20134.26), and overweight\/obesity and sleep duration\u2009\u2264\u20097\u00a0h (OR\u2009=\u20091.88, 95% CI: 1.01\u20133.49) were associated with increased odds of infertility, respectively.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>There was combined effects of trouble sleeping\/sleep duration\u2009\u2264\u20097\u00a0h and overweight\/obesity\/ abdominal obesity on increased odds of female infertility.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12905-024-03164-2","type":"journal-article","created":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T05:01:54Z","timestamp":1717218114000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Combined impact of sleep and obesity on female infertility in\u00a0the\u00a0NHANES 2017\u20132020"],"prefix":"10.1186","volume":"24","author":[{"given":"Zhe","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun-Hui","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song-Yu","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Dong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi-Ling","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,6,1]]},"reference":[{"key":"3164_CR1","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1016\/j.clinbiochem.2018.03.012","volume":"62","author":"M Vander Borght","year":"2018","unstructured":"Vander Borght M, Wyns C. 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