{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T17:26:39Z","timestamp":1793726799323,"version":"4.6.1"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T00:00:00Z","timestamp":1739836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T00:00:00Z","timestamp":1739836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Women's Health"],"DOI":"10.1186\/s12905-025-03601-w","type":"journal-article","created":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T14:14:47Z","timestamp":1739888087000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The application of progesterone-primed ovarian stimulation protocol in patients with ovarian endometriosis combined with diminished ovarian reserve"],"prefix":"10.1186","volume":"25","author":[{"given":"Qingqing","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijuan","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaqing","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,2,18]]},"reference":[{"key":"3601_CR1","doi-asserted-by":"publisher","first-page":"e070750","DOI":"10.1136\/bmj-2022-070750","volume":"379","author":"AW Horne","year":"2022","unstructured":"Horne AW, Missmer SA. Pathophysiology, diagnosis, and management of endometriosis. BMJ. 2022;379:e070750.","journal-title":"BMJ"},{"key":"3601_CR2","doi-asserted-by":"publisher","first-page":"1020827","DOI":"10.3389\/fendo.2022.1020827","volume":"13","author":"G Bonavina","year":"2022","unstructured":"Bonavina G, Taylor HS. Endometriosis-associated infertility: from pathophysiology to tailored treatment. Front Endocrinol (Lausanne). 2022;13:1020827.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"4","key":"3601_CR3","first-page":"e38136","volume":"15","author":"C Resta","year":"2023","unstructured":"Resta C, Moustogiannis A, Chatzinikita E, Malligiannis Ntalianis D, Malligiannis Ntalianis K, Philippou A, et al. Gonadotropin-releasing hormone (GnRH)\/GnRH receptors and their role in the treatment of endometriosis. Cureus. 2023;15(4):e38136.","journal-title":"Cureus"},{"issue":"11","key":"3601_CR4","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1097\/JCMA.0000000000000177","volume":"82","author":"CM Yu","year":"2019","unstructured":"Yu CM, Dai XL, Wang YF, Gao TT, Cao F, Xia XY, et al. Progestin-primed ovarian stimulation improves the outcomes of IVF\/ICSI cycles in infertile women with diminished ovarian reserve. J Chin Med Assoc. 2019;82(11):845\u20138.","journal-title":"J Chin Med Assoc"},{"issue":"8","key":"3601_CR5","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1007\/s10815-014-0257-5","volume":"31","author":"AD Greene","year":"2014","unstructured":"Greene AD, Patounakis G, Segars JH. Genetic associations with diminished ovarian reserve: a systematic review of the literature. J Assist Reprod Genet. 2014;31(8):935\u201346.","journal-title":"J Assist Reprod Genet"},{"issue":"6","key":"3601_CR6","doi-asserted-by":"publisher","first-page":"1270","DOI":"10.1093\/humrep\/der037","volume":"26","author":"Alpha Scientists in Reproductive Me","year":"2011","unstructured":"Alpha Scientists in Reproductive Medicine and ESHRE Special Interest Group of Embryology. The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting. Hum Reprod. 2011;26(6):1270\u201383.","journal-title":"Hum Reprod"},{"issue":"6","key":"3601_CR7","doi-asserted-by":"publisher","first-page":"1155","DOI":"10.1016\/S0015-0282(00)00518-5","volume":"73","author":"DK Gardner","year":"2000","unstructured":"Gardner DK, Lane M, Stevens J, Schlenker T, Schoolcraft WB. Blastocyst score affects implantation and pregnancy outcome: towards a single blastocyst transfer. Fertil Steril. 2000;73(6):1155\u20138.","journal-title":"Fertil Steril"},{"issue":"2","key":"3601_CR8","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1093\/humupd\/dmt053","volume":"20","author":"AM Sanchez","year":"2014","unstructured":"Sanchez AM, Vigan\u00f2 P, Somigliana E, Panina-Bordignon P, Vercellini P, Candiani M. The distinguishing cellular and molecular features of the endometriotic ovarian cyst: from pathophysiology to the potential endometrioma-mediated damage to the ovary. Hum Reprod Update. 2014;20(2):217\u201330.","journal-title":"Hum Reprod Update"},{"issue":"2","key":"3601_CR9","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1016\/j.fertnstert.2019.09.031","volume":"113","author":"RM Hodgson","year":"2020","unstructured":"Hodgson RM, Lee HL, Wang R, Mol BW, Johnson N. Interventions for endometriosis-related infertility: a systematic review and network meta-analysis. Fertil Steril. 2020;113(2):374\u201382.","journal-title":"Fertil Steril"},{"issue":"7","key":"3601_CR10","doi-asserted-by":"publisher","first-page":"1786","DOI":"10.1093\/humrep\/dei002","volume":"20","author":"B Schubert","year":"2005","unstructured":"Schubert B, Canis M, Darcha C, Artonne C, Pouly JL, D\u00e9chelotte P, et al. Human ovarian tissue from cortex surrounding benign cysts: a model to study ovarian tissue cryopreservation. Hum Reprod. 2005;20(7):1786\u201392.","journal-title":"Hum Reprod"},{"issue":"11","key":"3601_CR11","doi-asserted-by":"publisher","first-page":"5547","DOI":"10.1210\/jc.2019-00281","volume":"104","author":"A Takeuchi","year":"2019","unstructured":"Takeuchi A, Koga K, Satake E, Makabe T, Taguchi A, Miyashita M, et al. Endometriosis triggers excessive activation of primordial follicles via PI3K-PTEN-Akt-Foxo3 pathway. J Clin Endocrinol Metab. 2019;104(11):5547\u201354.","journal-title":"J Clin Endocrinol Metab"},{"key":"3601_CR12","doi-asserted-by":"publisher","first-page":"1397279","DOI":"10.3389\/fendo.2024.1397279","volume":"15","author":"JS Younis","year":"2024","unstructured":"Younis JS, Taylor HS. The impact of ovarian endometrioma and endometriotic cystectomy on anti-M\u00fcllerian hormone, and antral follicle count: a contemporary critical appraisal of systematic reviews. Front Endocrinol (Lausanne). 2024;15:1397279.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"1","key":"3601_CR13","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/j.rbmo.2020.09.014","volume":"42","author":"Z Tian","year":"2021","unstructured":"Tian Z, Zhang Y, Zhang C, Wang Y, Zhu HL. Antral follicle count is reduced in the presence of endometriosis: a systematic review and meta-analysis. Reprod Biomed Online. 2021;42(1):237\u201347.","journal-title":"Reprod Biomed Online"},{"issue":"1","key":"3601_CR14","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1002\/ijgo.14621","volume":"162","author":"G Riemma","year":"2023","unstructured":"Riemma G, De Franciscis P, La Verde M, Ravo M, Fumiento P, Fasulo DD, et al. Impact of the hemostatic approach after laparoscopic endometrioma excision on ovarian reserve: systematic review and network meta-analysis of randomized controlled trials. Int J Gynaecol Obstet. 2023;162(1):222\u201332.","journal-title":"Int J Gynaecol Obstet"},{"issue":"1","key":"3601_CR15","first-page":"CD004635","volume":"2006","author":"HN Sallam","year":"2006","unstructured":"Sallam HN, Garcia-Velasco JA, Dias S, Arici A. Long-term pituitary down-regulation before in vitro fertilization (IVF) for women with endometriosis. Cochrane Database Syst Rev. 2006;2006(1):CD004635.","journal-title":"Cochrane Database Syst Rev"},{"issue":"1","key":"3601_CR16","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1002\/ijgo.14690","volume":"162","author":"X Wang","year":"2023","unstructured":"Wang X, Li W, Chen X, Zhang W, Chu M, Yin S, et al. Is the long-acting gonadotropin-releasing hormone agonist long protocol better for patients with endometriosis undergoing IVF? Int J Gynaecol Obstet. 2023;162(1):325\u201332.","journal-title":"Int J Gynaecol Obstet"},{"key":"3601_CR17","doi-asserted-by":"publisher","first-page":"1232935","DOI":"10.3389\/fendo.2023.1232935","volume":"14","author":"G Lin","year":"2023","unstructured":"Lin G, Zhong X, Li S, Liu X, Xu L. The clinical value of progestin-primed ovarian stimulation protocol for women with diminished ovarian reserve undergoing IVF\/ICSI: a systematic review and meta-analysis. Front Endocrinol (Lausanne). 2023;14:1232935.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"3","key":"3601_CR18","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1097\/GCO.0000000000000710","volume":"33","author":"B Ata","year":"2021","unstructured":"Ata B, Telek SB. Assisted reproductive technology for women with endometriosis, a clinically oriented review. Curr Opin Obstet Gynecol. 2021;33(3):225\u201331.","journal-title":"Curr Opin Obstet Gynecol"},{"key":"3601_CR19","doi-asserted-by":"publisher","first-page":"702558","DOI":"10.3389\/fendo.2021.702558","volume":"12","author":"S Guan","year":"2021","unstructured":"Guan S, Feng Y, Huang Y, Huang J. Progestin-primed ovarian stimulation protocol for patients in assisted Reproductive Technology: a Meta-analysis of Randomized controlled trials. Front Endocrinol (Lausanne). 2021;12:702558.","journal-title":"Front Endocrinol (Lausanne)"},{"key":"3601_CR20","doi-asserted-by":"publisher","first-page":"801026","DOI":"10.3389\/fendo.2021.801026","volume":"12","author":"X Tu","year":"2022","unstructured":"Tu X, You B, Jing M, Lin C, Zhang R. Progestin-primed ovarian stimulation Versus mild stimulation protocol in Advanced Age Women with diminished Ovarian Reserve undergoing their first in Vitro Fertilization cycle: a retrospective cohort study. Front Endocrinol (Lausanne). 2022;12:801026.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"6","key":"3601_CR21","doi-asserted-by":"publisher","first-page":"2514","DOI":"10.1210\/jcem.87.6.8526","volume":"87","author":"D Zhao","year":"2002","unstructured":"Zhao D, Lebovic DI, Taylor RN. Long-term progestin treatment inhibits RANTES (regulated on activation, normal T cell expressed and secreted) gene expression in human endometrial stromal cells. J Clin Endocrinol Metab. 2002;87(6):2514\u20139.","journal-title":"J Clin Endocrinol Metab"},{"key":"3601_CR22","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/j.ejogrb.2022.08.001","volume":"276","author":"J Yu","year":"2022","unstructured":"Yu J, Zhu D, Zeng C, Zhang Y, Yang H, Xu Y. MicroRNA expression profiles in the granulosa cells of infertile patients undergoing progestin primed ovarian stimulation. Eur J Obstet Gynecol Reprod Biol. 2022;276:228\u201335.","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"3601_CR23","doi-asserted-by":"publisher","first-page":"798434","DOI":"10.3389\/fendo.2022.798434","volume":"13","author":"AM Yang","year":"2022","unstructured":"Yang AM, Feng TF, Han Y, Zhao ZM, Wang W, Wang YZ, et al. Progestin-primed ovarian stimulation protocol for patients with Endometrioma. Front Endocrinol (Lausanne). 2022;13:798434.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"1","key":"3601_CR24","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1186\/s13048-020-00620-z","volume":"13","author":"E Mathieu d\u2019Argent","year":"2020","unstructured":"Mathieu d\u2019Argent E, Ferrier C, Zacharopoulou C, Ahdad-Yata N, Boudy AS, Cantalloube A, et al. Outcomes of fertility preservation in women with endometriosis: comparison of progestin-primed ovarian stimulation versus antagonist protocols. J Ovarian Res. 2020;13(1):18.","journal-title":"J Ovarian Res"},{"key":"3601_CR25","doi-asserted-by":"publisher","first-page":"5459","DOI":"10.2147\/DDDT.S263138","volume":"14","author":"Z Liang","year":"2020","unstructured":"Liang Z, Wang Y, Kuang Y. Live-birth outcomes and congenital malformations after Progestin-primed ovarian stimulation in maternal endometriosis. Drug Des Devel Ther. 2020;14:5459\u201367.","journal-title":"Drug Des Devel Ther"},{"issue":"1","key":"3601_CR26","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1186\/s12978-023-01671-3","volume":"20","author":"J Li","year":"2023","unstructured":"Li J, Li Y, Li M, Zhao X, Zheng W, Zhang J, et al. Analysis of cumulative live birth rate outcomes of three ovarian stimulation protocols in patients after laparoscopic cystectomy of ovarial endometrioma: a retrospective cohort study. Reprod Health. 2023;20(1):126.","journal-title":"Reprod Health"},{"key":"3601_CR27","doi-asserted-by":"publisher","first-page":"1461132","DOI":"10.3389\/fcell.2024.1461132","volume":"12","author":"I Iavarone","year":"2024","unstructured":"Iavarone I, Mele D, Caprio F, Andreoli G, Vastarella MG, de Franciscis P, et al. Obesity may impair response to ovarian stimulation. A retrospective observational study on oocyte quality. Front Cell Dev Biol. 2024;12:1461132.","journal-title":"Front Cell Dev Biol"},{"issue":"9","key":"3601_CR28","doi-asserted-by":"publisher","first-page":"2053","DOI":"10.1093\/humrep\/deae154","volume":"39","author":"A Morimoto","year":"2024","unstructured":"Morimoto A, Rose RD, Smith KM, Dinh DT, Umehara T, Winstanley YE, et al. Granulosa cell metabolism at ovulation correlates with oocyte competence and is disrupted by obesity and aging. Hum Reprod. 2024;39(9):2053\u201366.","journal-title":"Hum Reprod"}],"container-title":["BMC Women's Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12905-025-03601-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12905-025-03601-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12905-025-03601-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T14:14:49Z","timestamp":1739888089000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcwomenshealth.biomedcentral.com\/articles\/10.1186\/s12905-025-03601-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,18]]},"references-count":28,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["3601"],"URL":"https:\/\/doi.org\/10.1186\/s12905-025-03601-w","relation":{},"ISSN":["1472-6874"],"issn-type":[{"value":"1472-6874","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,18]]},"assertion":[{"value":"1 January 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 February 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 February 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The patients were given informed consent about the above treatment and the study was approved by the Reproductive Medicine Ethics Committee of Xuzhou Central Hospital. All methods were carried out in accordance with relevant guidelines and regulations. None of the authors has any commercial associations or financial disclosures that might pose or create a conflict of interest with information presented in this article. No external funding was received.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"70"}}