{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T05:38:12Z","timestamp":1794029892227,"version":"4.8.0"},"reference-count":63,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T00:00:00Z","timestamp":1754265600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T00:00:00Z","timestamp":1754265600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100007123","name":"Stanley Medical Research Institute","doi-asserted-by":"publisher","award":["07R-1888"],"award-info":[{"award-number":["07R-1888"]}],"id":[{"id":"10.13039\/100007123","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007123","name":"Stanley Medical Research Institute","doi-asserted-by":"publisher","award":["07R-1888"],"award-info":[{"award-number":["07R-1888"]}],"id":[{"id":"10.13039\/100007123","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007123","name":"Stanley Medical Research Institute","doi-asserted-by":"publisher","award":["07R-1888"],"award-info":[{"award-number":["07R-1888"]}],"id":[{"id":"10.13039\/100007123","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007123","name":"Stanley Medical Research Institute","doi-asserted-by":"publisher","award":["07R-1888"],"award-info":[{"award-number":["07R-1888"]}],"id":[{"id":"10.13039\/100007123","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Women's Health"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>While there exist safe hormonal and non-hormonal therapeutic interventions for the menopause, their efficacy profiles are not fully characterized. This study sought to use a symptom checklist to examine menopausal symptom relief associated with different treatments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      An online survey study was conducted between December 2023 and February 2024. Convenience sampling was conducted, with participants recruited via social media, email, through relevant foundations and support groups, and by word-of-mouth. Inclusion criteria were: (1)\u2009\u2265\u200918 years, (2) assigned female at birth, (3) strong comprehension of the English language, and (4) must be\n                      <jats:italic>currently<\/jats:italic>\n                      experiencing symptoms of the menopause or menopause transition. 3330 respondents consented to participate in the study and of these, 91.95% (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u20093062) who had completed at least 88% of the survey were included in the analysis. Symptom relief per treatment (transdermal hormone replacement therapy (HRT), oral HRT, vaginal HRT, antidepressants, testosterone, cognitive behavioral therapy (CBT)\/other therapy\/counseling) was assessed using the symptoms included in the Menopause-Specific Quality of Life (MENQOL) questionnaire, which measures four symptom domains: vasomotor, psychosocial, physical, and sexual.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Data from a total of 3062 respondents were included for analysis (mean age\u2009=\u200951.97, SD\u2009=\u20095.24). Treatment response rates differed significantly across the domains (vasomotor:\n                      <jats:italic>F<\/jats:italic>\n                      (5,2340)\u2009=\u2009204.93,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001, \u03b7\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.31; psychosocial:\n                      <jats:italic>F<\/jats:italic>\n                      (5,2340)\u2009=\u200975.12,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001, \u03b7\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.14; physical:\n                      <jats:italic>F<\/jats:italic>\n                      (5,2340)\u2009=\u200965.46,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001, \u03b7\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.12; sexual:\n                      <jats:italic>F<\/jats:italic>\n                      (5,2340)\u2009=\u200989.34,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001, \u03b7\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.16). Transdermal HRT performed better at reducing vasomotor symptoms relative to all other treatment options. Regarding psychosocial symptoms, CBT\/other therapy\/counseling outperformed all other treatment options. The use of transdermal HRT and testosterone was associated with greater response rates in physical symptoms relative to other treatments. Finally, vaginal HRT and testosterone were associated with significantly higher response rates in sexual symptoms in comparison to all other treatments.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The findings demonstrate differential response rates to menopausal treatments across symptom domains, underscoring the importance of a comprehensive, multidimensional approach to menopausal symptom management. Utilizing a symptom checklist can facilitate the tailoring of treatment plans for specific symptom profiles and patient needs. The outcomes of this study hold considerable implications for improving and shaping treatment guidelines for the menopause.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12905-025-03929-3","type":"journal-article","created":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T16:36:07Z","timestamp":1754325367000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Differential symptom relief profiles of menopausal therapies: an online survey study"],"prefix":"10.1186","volume":"25","author":[{"given":"Nayra A.","family":"Martin-Key","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin L.","family":"Funnell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakub","family":"Tomasik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Bahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,8,4]]},"reference":[{"issue":"9","key":"3929_CR1","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1093\/occmed\/kqy134","volume":"68","author":"C Hardy","year":"2018","unstructured":"Hardy C, Hunter MS, Griffiths A. Menopause and work: an overview of UK guidance. Occup Med. 2018;68(9):580\u20136.","journal-title":"Occup Med"},{"key":"3929_CR2","unstructured":"World Health Organization. World Health Report 2008: Women, Ageing and Health: A Framework for Action. 2008. Available from: https:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/43810\/9789241563529_eng.pdf [Accessed 24 March 2024]."},{"issue":"8","key":"3929_CR3","doi-asserted-by":"publisher","first-page":"250","DOI":"10.11124\/01938924-201513080-00018","volume":"13","author":"L Hoga","year":"2015","unstructured":"Hoga L, Rodolpho J, Gon\u00e7alves B, Quirino B. Women\u02bcs experience of menopause: a systematic review of qualitative evidence. JBI Database Syst Reviews Implement Rep. 2015;13(8):250\u2013337.","journal-title":"JBI Database Syst Reviews Implement Rep"},{"issue":"5","key":"3929_CR4","doi-asserted-by":"publisher","first-page":"874","DOI":"10.1016\/S0015-0282(01)02909-0","volume":"76","author":"MR Soules","year":"2001","unstructured":"Soules MR, Sherman S, Parrott E, Rebar R, Santoro N, Utian W, et al. Executive summary: stages of reproductive aging workshop (STRAW). Fertil Steril. 2001;76(5):874\u20138.","journal-title":"Fertil Steril"},{"issue":"10","key":"3929_CR5","doi-asserted-by":"publisher","first-page":"1038","DOI":"10.1097\/GME.0000000000000319","volume":"21","author":"JL Shifren","year":"2014","unstructured":"Shifren JL, Gass MLS. The North American menopause society recommendations for clinical care of midlife women. Menopause. 2014;21(10):1038\u201362.","journal-title":"Menopause"},{"issue":"4","key":"3929_CR6","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1001\/jamainternmed.2014.8063","volume":"175","author":"NE Avis","year":"2015","unstructured":"Avis NE, Crawford SL, Greendale G, Bromberger JT, Everson-Rose SA, Gold EB, et al. Duration of menopausal vasomotor symptoms over the menopause transition. JAMA Intern Med. 2015;175(4):531.","journal-title":"JAMA Intern Med"},{"issue":"2","key":"3929_CR7","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1111\/tog.12553","volume":"21","author":"FG Dave","year":"2019","unstructured":"Dave FG, Adedipe T, Disu S, Laiyemo R. Unscheduled bleeding with hormone replacement therapy. Obstetrician Gynaecologist. 2019;21(2):95\u2013101.","journal-title":"Obstetrician Gynaecologist"},{"issue":"1","key":"3929_CR8","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.maturitas.2007.06.004","volume":"58","author":"Z Kara\u00e7am","year":"2007","unstructured":"Kara\u00e7am Z, \u015eeker SE. Factors associated with menopausal symptoms and their relationship with the quality of life among Turkish women. Maturitas. 2007;58(1):75\u201382.","journal-title":"Maturitas"},{"issue":"11","key":"3929_CR9","doi-asserted-by":"publisher","first-page":"1262","DOI":"10.1097\/01.MLR.0000093479.39115.AF","volume":"41","author":"NE Avis","year":"2003","unstructured":"Avis NE, Ory M, Matthews KA, Schocken M, Bromberger J, Colvin A. Health-Related quality of life in a multiethnic sample of Middle-Aged women. Med Care. 2003;41(11):1262\u201376.","journal-title":"Med Care"},{"issue":"5","key":"3929_CR10","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1097\/gme.0b013e3181a3cdaf","volume":"16","author":"NE Avis","year":"2009","unstructured":"Avis NE, Colvin A, Bromberger JT, Hess R, Matthews KA, Ory M, et al. Change in health-related quality of life over the menopausal transition in a multiethnic cohort of middle-aged women. Menopause. 2009;16(5):860\u20139.","journal-title":"Menopause"},{"issue":"2","key":"3929_CR11","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.maturitas.2008.12.006","volume":"62","author":"RE Williams","year":"2009","unstructured":"Williams RE, Levine KB, Kalilani L, Lewis J, Clark RV. Menopause-specific questionnaire assessment in US population-based study shows negative impact on health-related quality of life. Maturitas. 2009;62(2):153\u20139.","journal-title":"Maturitas"},{"issue":"6908","key":"3929_CR12","doi-asserted-by":"publisher","first-page":"836","DOI":"10.1136\/bmj.307.6908.836","volume":"307","author":"E Daly","year":"1993","unstructured":"Daly E, Gray A, Barlow D, McPherson K, Roche M, Vessey M. Measuring the impact of menopausal symptoms on quality of life. BMJ. 1993;307(6908):836\u201340.","journal-title":"BMJ"},{"issue":"4","key":"3929_CR13","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1016\/j.mcna.2019.03.001","volume":"103","author":"CN Soares","year":"2019","unstructured":"Soares CN. Depression and menopause. Med Clin North Am. 2019;103(4):651\u201367.","journal-title":"Med Clin North Am"},{"issue":"09","key":"3929_CR14","doi-asserted-by":"publisher","first-page":"1879","DOI":"10.1017\/S003329171100016X","volume":"41","author":"JT Bromberger","year":"2011","unstructured":"Bromberger JT, Kravitz HM, Chang YF, Cyranowski JM, Brown C, Matthews KA. Major depression during and after the menopausal transition: study of women\u2019s health across the Nation (SWAN). Psychol Med. 2011;41(09):1879\u201388.","journal-title":"Psychol Med"},{"issue":"5","key":"3929_CR15","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1089\/act.2019.29241.jha","volume":"25","author":"J Hart","year":"2019","unstructured":"Hart J, Menopause. Shifting hormones linked to anxiety and depression symptoms. Altern Complement Ther. 2019;25(5):254\u20136.","journal-title":"Altern Complement Ther"},{"issue":"1\u20132","key":"3929_CR16","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/j.jad.2008.12.006","volume":"116","author":"J Usall","year":"2009","unstructured":"Usall J, Pinto-Meza A, Fern\u00e1ndez A, de Graaf R, Demyttenaere K, Alonso J, et al. Suicide ideation across reproductive life cycle of women results from a European epidemiological study. J Affect Disord. 2009;116(1\u20132):144\u20137.","journal-title":"J Affect Disord"},{"key":"3929_CR17","doi-asserted-by":"crossref","unstructured":"Caretto M, Simoncini T. Hormone replacement therapy (HRT). Endocrinology. 2020;1\u201318.","DOI":"10.1007\/978-3-030-03594-5_18-1"},{"issue":"2","key":"3929_CR18","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1067\/mob.2000.106004","volume":"183","author":"PJ Schmidt","year":"2000","unstructured":"Schmidt PJ, Nieman L, Danaceau MA, Tobin MB, Roca CA, Murphy JH, et al. Estrogen replacement in perimenopause-related depression: A preliminary report. Am J Obstet Gynecol. 2000;183(2):414\u201320.","journal-title":"Am J Obstet Gynecol"},{"issue":"6","key":"3929_CR19","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1001\/archpsyc.58.6.529","volume":"58","author":"C Soares","year":"2001","unstructured":"Soares C, Almeida OP, Joffe H, Cohen LS. Efficacy of estradiol for the treatment of depressive disorders in perimenopausal women. Arch Gen Psychiatry. 2001;58(6):529.","journal-title":"Arch Gen Psychiatry"},{"issue":"7","key":"3929_CR20","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1001\/jamapsychiatry.2015.0111","volume":"72","author":"PJ Schmidt","year":"2015","unstructured":"Schmidt PJ, Ben Dor R, Martinez PE, Guerrieri GM, Harsh VL, Thompson K, et al. Effects of estradiol withdrawal on mood in women with past perimenopausal depression. JAMA Psychiatry. 2015;72(7):714.","journal-title":"JAMA Psychiatry"},{"issue":"10","key":"3929_CR21","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1097\/GME.0000000000002407","volume":"31","author":"JL Yang","year":"2024","unstructured":"Yang JL, Hodara E, Sriprasert Intira, Shoupe D, Stanczyk FZ. Estrogen deficiency in the menopause and the role of hormone therapy: integrating the findings of basic science research with clinical trials. Menopause. 2024;31(10):926\u201339.","journal-title":"Menopause"},{"key":"3929_CR22","unstructured":"NICE, Menopause. identification and management [Internet]. NICE; 2024 [updated 2024; cited 2025 Jun 25]. Available from: https:\/\/www.nice.org.uk\/guidance\/ng23\/chapter\/recommendations"},{"issue":"2","key":"3929_CR23","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1258\/mi.2009.009021","volume":"15","author":"A Graziottin","year":"2009","unstructured":"Graziottin A, Serafini A. Depression and the menopause: why antidepressants are not enough? Menopause Int. 2009;15(2):76\u201381.","journal-title":"Menopause Int"},{"key":"3929_CR24","doi-asserted-by":"publisher","first-page":"q220","DOI":"10.1136\/bmj.q220","volume":"384","author":"S Glynne","year":"2024","unstructured":"Glynne S, Newson L. Curb antidepressant use: perimenopausal women May benefit from HRT. BMJ. 2024;384:q220.","journal-title":"BMJ"},{"issue":"1","key":"3929_CR25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s44294-023-00001-z","volume":"1","author":"NA Martin-Key","year":"2023","unstructured":"Martin-Key NA, Funnell EL, Spadaro B, Bahn S. Perceptions of healthcare provision throughout the menopause in the UK: a mixed-methods study. Npj Women\u2019s Health. 2023;1(1):1\u201310.","journal-title":"Npj Women\u2019s Health"},{"key":"3929_CR26","unstructured":"National Institute for Health and Care Excellence. Clinical knowledge summary. Hormone replacement therapy (HRT). 2022. Available from: https:\/\/cks.nice.org.uk\/topics\/menopause\/prescribing-information\/hormone-replacement-therapy-hrt\/ [Accessed 3 April 2024]."},{"key":"3929_CR27","unstructured":"British Menopause Society. Cognitive Behaviour Therapy (CBT) for Menopausal Symptoms. 2019. Available from: https:\/\/thebms.org.uk\/wp-content\/uploads\/2022\/12\/01-BMS-TfC-CBT-NOV2022-A.pdf [Accessed 25 June 2025]."},{"issue":"8","key":"3929_CR28","doi-asserted-by":"publisher","first-page":"1205","DOI":"10.1001\/jamainternmed.2016.2761","volume":"176","author":"MA Lumsden","year":"2016","unstructured":"Lumsden MA, Davies M, Sarri G, Guideline Development Group for Menopause. Diagnosis and management (NICE clinical guideline 23). Diagnosis and management of menopause: the National Institute of health and care excellence (NICE) guideline. JAMA Intern Med. 2016;176(8):1205\u20136.","journal-title":"JAMA Intern Med"},{"issue":"693","key":"3929_CR29","doi-asserted-by":"publisher","first-page":"203","DOI":"10.3399\/bjgp20X709265","volume":"70","author":"A Scott","year":"2020","unstructured":"Scott A, Newson L. Should we be prescribing testosterone to perimenopausal and menopausal women? A guide to prescribing testosterone for women in primary care. Br J Gen Pract. 2020;70(693):203\u20134.","journal-title":"Br J Gen Pract"},{"key":"3929_CR30","doi-asserted-by":"crossref","unstructured":"Islam RM, Bell RJ, Green S, Page MJ, Davis SR. Safety and efficacy of testosterone for women: a systematic review and meta-analysis of randomised controlled trial data. Lancet Diabetes Endocrinol. 2019;7(10).","DOI":"10.1016\/S2213-8587(19)30189-5"},{"key":"3929_CR31","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.maturitas.2020.02.002","volume":"141","author":"H Hamoda","year":"2020","unstructured":"Hamoda H. Availability of menopausal hormone therapy products worldwide. Maturitas. 2020;141:87\u20138.","journal-title":"Maturitas"},{"key":"3929_CR32","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1038\/s44294-024-00045-9","volume":"2","author":"NA Martin-Key","year":"2024","unstructured":"Martin-Key NA, Funnell EL, Benacek J, Spadaro B, Bahn S. Using network analysis to understand the association between menopause and depressive symptoms. Npj Womens Health. 2024;2:41.","journal-title":"Npj Womens Health"},{"key":"3929_CR33","doi-asserted-by":"publisher","first-page":"e60434","DOI":"10.2196\/60434","volume":"8","author":"NA Martin-Key","year":"2024","unstructured":"Martin-Key NA, Funnell EL, Benacek J, Spadaro B, Bahn S. Intention to use a mental health app for menopause: health belief model approach. JMIR Form Res. 2024;8:e60434.","journal-title":"JMIR Form Res"},{"key":"3929_CR34","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1038\/s44294-023-00002-y","volume":"1","author":"NA Martin-Key","year":"2023","unstructured":"Martin-Key NA, Funnell EL, Spadaro B, Bahn S. Perceptions of healthcare provision throughout the menopause in the UK: a mixed-methods study. Npj Womens Health. 2023;1:2.","journal-title":"Npj Womens Health"},{"issue":"10","key":"3929_CR35","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1097\/GME.0000000000001424","volume":"26","author":"SR El Khoudary","year":"2019","unstructured":"El Khoudary SR, Greendale G, Crawford SL, Avis NE, Brooks MM, Thurston RC, et al. The menopause transition and women\u02bcs health at midlife. Menopause. 2019;26(10):1213\u201327.","journal-title":"Menopause"},{"issue":"3","key":"3929_CR36","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/S0378-5122(96)82006-8","volume":"24","author":"JR Hilditch","year":"1996","unstructured":"Hilditch JR, Lewis J, Peter A, van Maris B, Ross A, Franssen E, et al. A menopause-specific quality of life questionnaire: development and psychometric properties. Maturitas. 1996;24(3):161\u201375.","journal-title":"Maturitas"},{"issue":"1","key":"3929_CR37","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1007\/s11336-024-09964-7","volume":"89","author":"K Sijtsma","year":"2024","unstructured":"Sijtsma K, Ellis JL, Borsboom D. Recognize the value of the sum score, psychometrics\u2019 greatest accomplishment. Psychometrika. 2024;89(1):84\u2013117.","journal-title":"Psychometrika"},{"issue":"2","key":"3929_CR38","doi-asserted-by":"publisher","first-page":"788","DOI":"10.3758\/s13428-022-01849-w","volume":"55","author":"KF Widaman","year":"2023","unstructured":"Widaman KF, Revelle W. Thinking thrice about sum scores, and then some more about measurement and analysis. Behav Res Methods. 2023;55(2):788\u2013806.","journal-title":"Behav Res Methods"},{"issue":"6","key":"3929_CR39","doi-asserted-by":"publisher","first-page":"2233","DOI":"10.1007\/s12325-024-02787-z","volume":"41","author":"NM Schultz","year":"2024","unstructured":"Schultz NM, Morga A, Siddiqui E, Rhoten SE. Psychometric evaluation of the MENQOL instrument in women experiencing vasomotor symptoms associated with menopause. Adv Ther. 2024;41(6):2233\u201352.","journal-title":"Adv Ther"},{"issue":"3","key":"3929_CR40","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.maturitas.2004.06.015","volume":"50","author":"JE Lewis","year":"2005","unstructured":"Lewis JE, Hilditch JR, Wong CJ. Further psychometric property development of the Menopause-Specific quality of life questionnaire and development of a modified version, MENQOL-Intervention questionnaire. Maturitas. 2005;50(3):209\u201321.","journal-title":"Maturitas"},{"key":"3929_CR41","volume-title":"Statistical power analysis for the behavioral sciences","author":"J Cohen","year":"1988","unstructured":"Cohen J. Statistical power analysis for the behavioral sciences. 2nd ed. New York: Academic; 1988.","edition":"2"},{"issue":"4","key":"3929_CR42","doi-asserted-by":"publisher","first-page":"497","DOI":"10.3109\/13697137.2010.549974","volume":"14","author":"O Duffy","year":"2011","unstructured":"Duffy O, Iversen L, Hannaford PC. The menopause it\u2019s somewhere between a taboo and a joke. A focus group study. Climacteric. 2011;14(4):497\u2013505.","journal-title":"Climacteric"},{"issue":"2","key":"3929_CR43","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1097\/gme.0b013e3181c6b26f","volume":"17","author":"A Hyde","year":"2010","unstructured":"Hyde A, Nee J, Drennan J, Butler M, Howlett E. Hormone therapy and the medical encounter. Menopause. 2010;17(2):344\u201350.","journal-title":"Menopause"},{"key":"3929_CR44","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1111\/j.2044-8287.1996.tb00496.x","volume":"1","author":"MS Hunter","year":"1996","unstructured":"Hunter MS, Liao K-M. Evaluation of a four-session cognitive-behavioral intervention for menopausal hot flushes. Br J Health Psychol. 1996;1:113\u201325.","journal-title":"Br J Health Psychol"},{"issue":"1","key":"3929_CR45","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.maturitas.2013.09.013","volume":"77","author":"E Stefanopoulou","year":"2014","unstructured":"Stefanopoulou E, Hunter MS. Telephone-guided Self-Help cognitive behavioural therapy for menopausal symptoms. Maturitas. 2014;77(1):73\u20137.","journal-title":"Maturitas"},{"issue":"5","key":"3929_CR46","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1097\/GME.0000000000001048","volume":"25","author":"C Hardy","year":"2018","unstructured":"Hardy C, Griffiths A, Norton S, Hunter MS. Self-help cognitive behavior therapy for working women with problematic hot flushes and night sweats (MENOS@Work): a multicenter randomized controlled trial. Menopause. 2018;25(5):508\u201319.","journal-title":"Menopause"},{"issue":"5","key":"3929_CR47","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1002\/pon.1414","volume":"18","author":"MS Hunter","year":"2009","unstructured":"Hunter MS, Coventry S, Hamed H, Fentiman I, Grunfeld EA. Evaluation of a group cognitive behavioural intervention for women suffering from menopausal symptoms following breast cancer treatment. Psycho-oncology. 2009;18(5):560\u20133.","journal-title":"Psycho-oncology"},{"issue":"7","key":"3929_CR48","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1097\/gme.0b013e31823fe835","volume":"19","author":"B Ayers","year":"2012","unstructured":"Ayers B, Smith M, Hellier J, Mann E, Hunter MS. Effectiveness of group and self-help cognitive behavior therapy in reducing problematic menopausal hot flushes and night sweats (MENOS 2). Menopause: J North Am Menopause Soc. 2012;19(7):749\u201359.","journal-title":"Menopause: J North Am Menopause Soc"},{"key":"3929_CR49","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1016\/j.jad.2024.02.048","volume":"352","author":"A Spector","year":"2024","unstructured":"Spector A, Li Z, He L, Badawy Y, Desai R. The effectiveness of psychosocial interventions on non-physiological symptoms of menopause: A systematic review and meta-analysis. J Affect Disord. 2024;352:460\u201372.","journal-title":"J Affect Disord"},{"issue":"4","key":"3929_CR50","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1017\/S1352465812000677","volume":"41","author":"J Balabanovic","year":"2012","unstructured":"Balabanovic J, Ayers B, Hunter MS. Cognitive behaviour therapy for menopausal hot flushes and night sweats: A qualitative analysis of women\u2019s experiences of group and Self-Help CBT. Behav Cogn Psychother. 2012;41(4):441\u201357.","journal-title":"Behav Cogn Psychother"},{"key":"3929_CR51","doi-asserted-by":"crossref","unstructured":"Knowles SE, Toms G, Sanders C, Bee P, Lovell K, Rennick-Egglestone S et al. Qualitative Meta-Synthesis of User Experience of Computerised Therapy for Depression and Anxiety. Harris F, editor. PLoS ONE. 2014;9(1):e84323.","DOI":"10.1371\/journal.pone.0084323"},{"issue":"2","key":"3929_CR52","doi-asserted-by":"publisher","first-page":"412","DOI":"10.3390\/jcm13020412","volume":"13","author":"JH Kim","year":"2024","unstructured":"Kim JH, Yu HJ. The effectiveness of cognitive behavioral therapy on depression and sleep problems for climacteric women: A systematic review and Meta-Analysis. J Clin Med. 2024;13(2):412.","journal-title":"J Clin Med"},{"issue":"6","key":"3929_CR53","doi-asserted-by":"publisher","first-page":"e27132","DOI":"10.2196\/27132","volume":"23","author":"NA Martin-Key","year":"2021","unstructured":"Martin-Key NA, Spadaro B, Schei TS, Bahn S. Proof-of-Concept support for the development and implementation of a digital assessment for perinatal mental health: mixed methods study. J Med Internet Res. 2021;23(6):e27132.","journal-title":"J Med Internet Res"},{"issue":"2","key":"3929_CR54","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1080\/13284207.2021.1892453","volume":"25","author":"S Smith","year":"2021","unstructured":"Smith S, Paparo J, Wootton BM. Understanding psychological treatment barriers, preferences and histories of individuals with clinically significant depressive symptoms in australia: a preliminary study. Clin Psychol. 2021;25(2):223\u201333.","journal-title":"Clin Psychol"},{"issue":"10","key":"3929_CR55","doi-asserted-by":"publisher","first-page":"4660","DOI":"10.1210\/jc.2019-01603","volume":"104","author":"SR Davis","year":"2019","unstructured":"Davis SR, Baber R, Panay N, Bitzer J, Perez SC, Islam RM, Kaunitz AM, Kingsberg SA, Lambrinoudaki I, Liu J, Parish SJ, Pinkerton J, Rymer J, Simon JA, Vignozzi L, Wierman ME. Global consensus position statement on the use of testosterone therapy for women. J Clin Endocrinol Metabolism. 2019;104(10):4660\u20136.","journal-title":"J Clin Endocrinol Metabolism"},{"issue":"12","key":"3929_CR56","doi-asserted-by":"publisher","first-page":"980","DOI":"10.1016\/S2213-8587(15)00284-3","volume":"3","author":"SR Davis","year":"2015","unstructured":"Davis SR, Wahlin-Jacobsen S. Testosterone in women\u2013the clinical significance. Lancet Diabetes Endocrinol. 2015;3(12):980\u201392.","journal-title":"Lancet Diabetes Endocrinol"},{"key":"3929_CR57","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.maturitas.2022.08.009","volume":"166","author":"BE Macpherson","year":"2022","unstructured":"Macpherson BE, Quinton ND. Menopause and healthcare professional education: A scoping review. Maturitas. 2022;166:89\u201395.","journal-title":"Maturitas"},{"key":"3929_CR58","doi-asserted-by":"publisher","first-page":"2971","DOI":"10.2147\/PPA.S430203","volume":"17","author":"K Barber","year":"2023","unstructured":"Barber K, Charles A. Barriers to accessing effective treatment and support for menopausal symptoms: A qualitative study capturing the behaviours, beliefs and experiences of key stakeholders. Patient Prefer Adherence. 2023;17:2971\u201380.","journal-title":"Patient Prefer Adherence"},{"issue":"6","key":"3929_CR59","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1080\/13697137.2024.2395986","volume":"27","author":"D Farah","year":"2024","unstructured":"Farah D, Ceccaldi PF, Farah L, Ayoubi JM, Vall\u00e9e A. Willingness to use clinical scales for menopause management among general practitioners. Climacteric. 2024;27(6):555\u201360.","journal-title":"Climacteric"},{"issue":"jul16 1","key":"3929_CR60","doi-asserted-by":"publisher","first-page":"a485","DOI":"10.1136\/bmj.a485","volume":"337","author":"P Kinnersley","year":"2008","unstructured":"Kinnersley P, Edwards A, Hood K, Ryan R, Prout H, Cadbury N, et al. Interventions before consultations to help patients address their information needs by encouraging question asking: systematic review. BMJ. 2008;337(jul16 1):a485\u20135.","journal-title":"BMJ"},{"key":"3929_CR61","doi-asserted-by":"crossref","unstructured":"Turner GM, Mullis R, Lim L, Kreit L, Mant J. Using a checklist to facilitate management of long-term care needs after stroke: insights from focus groups and a feasibility study. BMC Fam Pract. 2019;20(1).","DOI":"10.1186\/s12875-018-0894-3"},{"issue":"5","key":"3929_CR62","doi-asserted-by":"publisher","first-page":"e2316283","DOI":"10.1001\/jamanetworkopen.2023.16283","volume":"6","author":"TE Matson","year":"2023","unstructured":"Matson TE, Hallgren KA, Lapham GT, Oliver M, Wang X, Williams EC, et al. Psychometric performance of a substance use symptom checklist to help clinicians assess substance use disorder in primary care. JAMA Netw Open. 2023;6(5):e2316283\u20133.","journal-title":"JAMA Netw Open"},{"issue":"11","key":"3929_CR63","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1097\/GME.0000000000002061","volume":"29","author":"A Pershad","year":"2022","unstructured":"Pershad A, Morris JM, Pace D, Khanna P. Racial disparities in menopausal hormone therapy acceptance: a pilot study. Menopause. 2022;29(11):1263\u20138.","journal-title":"Menopause"}],"container-title":["BMC Women's Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12905-025-03929-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12905-025-03929-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12905-025-03929-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T14:00:16Z","timestamp":1757340016000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcwomenshealth.biomedcentral.com\/articles\/10.1186\/s12905-025-03929-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,4]]},"references-count":63,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["3929"],"URL":"https:\/\/doi.org\/10.1186\/s12905-025-03929-3","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-4957731\/v1","asserted-by":"object"}]},"ISSN":["1472-6874"],"issn-type":[{"value":"1472-6874","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,4]]},"assertion":[{"value":"22 August 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 July 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 August 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was approved by the University of Cambridge Psychology Research Ethics Committee (approval number PRE.2023.123). All participants provided informed consent electronically to participate in the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Author SB holds shares in Psyomics Ltd but declares no non-financial competing interests. Author EF is a paid consultant for Psyomics Ltd but declares no non-financial competing interests. Author JT received payment for licensing unrelated research data to Psyomics Ltd. Author NM-K declares no financial or non-financial competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"384"}}