{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T23:45:18Z","timestamp":1785714318407,"version":"3.56.0"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T00:00:00Z","timestamp":1779753600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T00:00:00Z","timestamp":1785715200000},"content-version":"vor","delay-in-days":69,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Women's Health"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Health-related quality of life (HRQoL) is a key outcome in breast cancer survivorship, yet population-referenced data for working-age women, a group facing distinct social and functional challenges, in Central and Eastern Europe remain scarce. We aimed to quantify HRQoL among Croatian working-age women with breast cancer and to benchmark patient-reported outcomes against national female population norms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a multicentre cross-sectional study in 2024 at two tertiary oncology centres in Croatia. Women aged 18\u201365 years attending outpatient breast cancer care completed the EQ-5D-5\u00a0L (dimensions, EQ-VAS and utility index) and the EORTC QLQ-BR23. EQ-5D-5\u00a0L utilities were calculated using the Slovenian value set and compared with age-stratified Croatian female population norms (2022). Group differences were analysed using appropriate non-parametric tests.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In total, 271 women participated, with 233 included in EQ-5D-5\u00a0L analyses. Mean EQ-5D-5\u00a0L utility was substantially lower among patients than in the general female population (0.76 vs. 0.91), accompanied by lower EQ-VAS scores (66.2 vs. 84.0). Problems were most frequently reported in pain\/discomfort and anxiety\/depression. HRQoL declined with age (utility 0.82 to 0.70;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03) and was significantly lower in women with metastatic disease compared with non-metastatic disease (0.70 vs. 0.77;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03). Disease-specific assessment revealed pronounced impairments in future perspective and sexual functioning\/enjoyment, alongside notable symptom burden related to systemic therapy side effects and arm and breast symptoms.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Working-age women with breast cancer in Croatia experience clinically meaningful reductions in HRQoL compared with national population norms, with higher burden among older women and those with metastatic disease. These findings highlight substantial unmet survivorship care needs and support the integration of routine patient-reported outcome monitoring into oncology follow-up, alongside targeted symptom management, psychosocial support, rehabilitation and sexual health care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12905-026-04562-4","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T06:05:11Z","timestamp":1779775511000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Health-related quality of life among working-age women with breast cancer in Croatia: a population-referenced cross-sectional study"],"prefix":"10.1186","volume":"26","author":[{"given":"Vid","family":"Duplan\u010di\u0107","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Bobinac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luka","family":"Von\u010dina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarina","family":"Hraste","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Te\u010di\u0107","family":"Vuger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"\u0160eparovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduard","family":"Vrdoljak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,26]]},"reference":[{"key":"4562_CR1","doi-asserted-by":"publisher","first-page":"1154","DOI":"10.1038\/s41591-025-03502-3","volume":"31","author":"J Kim","year":"2025","unstructured":"Kim J, Harper A, McCormack V, Sung H, Houssami N, Morgan E, et al. Global patterns and trends in breast cancer incidence and mortality across 185 countries. Nat Med. 2025;31:1154\u201362. https:\/\/doi.org\/10.1038\/s41591-025-03502-3.","journal-title":"Nat Med"},{"issue":"1","key":"4562_CR2","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1093\/jnci\/94.1.39","volume":"94","author":"PA Ganz","year":"2002","unstructured":"Ganz PA, Desmond KA, Leedham B, Rowland JH, Meyerowitz BE, Belin TR. Quality of life in long-term, disease-free survivors of breast cancer: a follow-up study. J Natl Cancer Inst. 2002;94(1):39\u201349. https:\/\/doi.org\/10.1093\/jnci\/94.1.39.","journal-title":"J Natl Cancer Inst"},{"issue":"1","key":"4562_CR3","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1186\/s12905-023-02769-3","volume":"23","author":"S Mahlaq","year":"2023","unstructured":"Mahlaq S, Lahlou L, Rammouz I, Abouqal R, Belayachi J. Factors associated with psychological burden of breast cancer in women in Morocco: cross-sectional study. BMC Womens Health. 2023;23(1):590. https:\/\/doi.org\/10.1186\/s12905-023-02769-3.","journal-title":"BMC Womens Health"},{"issue":"5","key":"4562_CR4","first-page":"161","volume":"47","author":"LL Northouse","year":"1992","unstructured":"Northouse LL. Psychological impact of the diagnosis of breast cancer on the patient and her family. J Am Med Womens Assoc (1972). 1992;47(5):161\u20134.","journal-title":"J Am Med Womens Assoc (1972)"},{"key":"4562_CR5","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1007\/s00520-024-08695-w","volume":"32","author":"S Sperlich","year":"2024","unstructured":"Sperlich S, Noeres D, Holthausen-Markou S, Park-Simon TW, Sahiti E, Geyer S. Social participation of women with breast cancer compared to the general population 5 years after primary surgery\u2014what role do medical data and cancer-related complaints play? Support Care Cancer. 2024;32:566. https:\/\/doi.org\/10.1007\/s00520-024-08695-w.","journal-title":"Support Care Cancer"},{"issue":"1","key":"4562_CR6","doi-asserted-by":"publisher","first-page":"e11","DOI":"10.1016\/S1470-2045(22)00540-X","volume":"24","author":"M Lawler","year":"2023","unstructured":"Lawler M, Davies L, Oberst S, Oliver K, Eggermont A, Schmutz A, et al. European Groundshot-addressing Europe\u2019s cancer research challenges: a Lancet Oncology Commission. Lancet Oncol. 2023;24(1):e11\u201356. https:\/\/doi.org\/10.1016\/S1470-2045(22)00540-X.","journal-title":"Lancet Oncol"},{"key":"4562_CR7","doi-asserted-by":"publisher","first-page":"1420178","DOI":"10.3389\/fonc.2024.1420178","volume":"14","author":"V Coppini","year":"2024","unstructured":"Coppini V, Ferraris G, Ferrari MV, Dah\u00f2 M, Kirac I, Renko I, et al. Patients\u2019 perspectives on cancer care disparities in Central and Eastern European countries: experiencing taboos, misinformation and barriers in the healthcare system. Front Oncol. 2024;14:1420178. https:\/\/doi.org\/10.3389\/fonc.2024.1420178.","journal-title":"Front Oncol"},{"key":"4562_CR8","doi-asserted-by":"publisher","first-page":"864","DOI":"10.3389\/fonc.2020.00864","volume":"10","author":"S Nardin","year":"2020","unstructured":"Nardin S, Mora E, Varughese FM, D\u2019Avanzo F, Vachanaram AR, Rossi V, et al. Breast Cancer Survivorship, Quality of Life, and Late Toxicities. Front Oncol. 2020;10:864. https:\/\/doi.org\/10.3389\/fonc.2020.00864.","journal-title":"Front Oncol"},{"key":"4562_CR9","doi-asserted-by":"publisher","DOI":"10.1787\/b3704e14-en","volume-title":"Health at a Glance: Europe 2024: State of Health in the EU Cycle","author":"OECD\/European Commission","year":"2024","unstructured":"OECD\/European Commission. Health at a Glance: Europe 2024: State of Health in the EU Cycle. Paris: OECD Publishing; 2024. https:\/\/doi.org\/10.1787\/b3704e14-en."},{"issue":"4","key":"4562_CR10","first-page":"1335","volume":"36","author":"J Murgi\u0107","year":"2012","unstructured":"Murgi\u0107 J, Soldi\u0107 Z, Vrlji\u0107 D, Samija I, Kirac I, Bolanca A, et al. Quality of life of Croatian breast cancer patients receiving adjuvant treatment\u2013comparison to long-term breast cancer survivors. Coll Antropol. 2012;36(4):1335\u201341. PMID: 23390830.","journal-title":"Coll Antropol"},{"key":"4562_CR11","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1186\/s12889-018-5929-0","volume":"18","author":"S Pa\u010dari\u0107","year":"2018","unstructured":"Pa\u010dari\u0107 S, Kristek J, Mirat J, Kond\u017ea G, Turk T. The quality of life of Croatian women after mastectomy: a cross-sectional single-center study. BMC Public Health. 2018;18:999. https:\/\/doi.org\/10.1186\/s12889-018-5929-0. Far\u010di\u0107, N., et al.","journal-title":"BMC Public Health"},{"issue":"2","key":"4562_CR12","doi-asserted-by":"publisher","first-page":"209","DOI":"10.20471\/acc.2020.59.02.02","volume":"59","author":"T \u017digman","year":"2020","unstructured":"\u017digman T, Luk\u0161a I, Mihaljevi\u0107 G, \u017darkovi\u0107 M, Kirac I, Vrdoljak DV, et al. Defining health-related quality of life in localized and advanced stages of breast cancer - the first step towards hereditary cancer genetic counseling. Acta Clin Croat. 2020;59(2):209\u201315. https:\/\/doi.org\/10.20471\/acc.2020.59.02.02.","journal-title":"Acta Clin Croat"},{"issue":"10","key":"4562_CR13","doi-asserted-by":"publisher","first-page":"1727","DOI":"10.1007\/s11136-011-9903-x","volume":"20","author":"M Herdman","year":"2011","unstructured":"Herdman M, Gudex C, Lloyd A, Janssen M, Kind P, Parkin D, et al. Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5L). Qual Life Res. 2011;20(10):1727\u201336. https:\/\/doi.org\/10.1007\/s11136-011-9903-x.","journal-title":"Qual Life Res"},{"key":"4562_CR14","unstructured":"EuroQol Research Foundation. EQ-5D-5L User Guide: Basic information on how to use the EQ-5D-5L instrument. Rotterdam: EuroQol Research Foundation. 2019. Available from: https:\/\/euroqol.org\/information-and-support\/documentation\/user-guides\/. Accessed 2025 Dec 25."},{"issue":"11","key":"4562_CR15","doi-asserted-by":"publisher","first-page":"1515","DOI":"10.1007\/s40273-023-01280-9","volume":"41","author":"V Prevolnik Rupel","year":"2023","unstructured":"Prevolnik Rupel V, Ogorevc M. EQ-5D-5L Value Set for Slovenia. PharmacoEconomics. 2023;41(11):1515\u201324. https:\/\/doi.org\/10.1007\/s40273-023-01280-9.","journal-title":"PharmacoEconomics"},{"issue":"10","key":"4562_CR16","doi-asserted-by":"publisher","first-page":"2756","DOI":"10.1200\/JCO.1996.14.10.2756","volume":"14","author":"MAG Sprangers","year":"1996","unstructured":"Sprangers MAG, Groenvold M, Arraras JI, Franklin J, te Velde A, Muller M, et al. The European Organization for Research and Treatment of Cancer breast cancer-specific quality-of-life questionnaire module: first results from a three-country field study. J Clin Oncol. 1996;14(10):2756\u201368. https:\/\/doi.org\/10.1200\/JCO.1996.14.10.2756.","journal-title":"J Clin Oncol"},{"key":"4562_CR17","unstructured":"Fayers PM, Aaronson NK, Bjordal K, Groenvold M, Curran D, Bottomley A, on behalf of the EORTC Quality of Life Group. The EORTC QLQ-C30 Scoring Manual. 3rd ed [Internet]. Brussels: European Organisation for Research and Treatment of Cancer; 2001. Available from: https:\/\/www.eortc.org\/app\/uploads\/sites\/2\/2018\/02\/SCmanual.pdf. Accessed 2025 Dec 25."},{"issue":"1","key":"4562_CR18","doi-asserted-by":"publisher","first-page":"22","DOI":"10.4103\/2347-5625.135817","volume":"1","author":"ML Tan","year":"2014","unstructured":"Tan ML, Idris DB, Teo LW, Loh SY, Seow GC, Chia YY, et al. Validation of EORTC QLQ-C30 and QLQ-BR23 questionnaires in the measurement of quality of life of breast cancer patients in Singapore. Asia Pac J Oncol Nurs. 2014;1(1):22\u201332. https:\/\/doi.org\/10.4103\/2347-5625.135817.","journal-title":"Asia Pac J Oncol Nurs"},{"key":"4562_CR19","doi-asserted-by":"publisher","first-page":"1955","DOI":"10.3390\/healthcare11131955","volume":"11","author":"A Bobinac","year":"2023","unstructured":"Bobinac A. Access to Healthcare and Health Literacy in Croatia: Empirical Investigation. Healthcare. 2023;11:1955. https:\/\/doi.org\/10.3390\/healthcare11131955.","journal-title":"Healthcare"},{"key":"4562_CR20","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1186\/1477-7525-5-70","volume":"5","author":"AS Pickard","year":"2007","unstructured":"Pickard AS, Neary MP, Cella D. Estimation of minimally important differences in EQ-5D utility and VAS scores in cancer. Health Qual Life Outcomes. 2007;5:70. https:\/\/doi.org\/10.1186\/1477-7525-5-70.","journal-title":"Health Qual Life Outcomes"},{"issue":"4","key":"4562_CR21","doi-asserted-by":"publisher","first-page":"644","DOI":"10.1016\/j.jval.2016.11.015","volume":"20","author":"NS McClure","year":"2017","unstructured":"McClure NS, Sayah FA, Xie F, Luo N, Johnson JA. Instrument-Defined Estimates of the Minimally Important Difference for EQ-5D-5L Index Scores. Value Health. 2017;20(4):644\u201350. https:\/\/doi.org\/10.1016\/j.jval.2016.11.015.","journal-title":"Value Health"},{"issue":"e3","key":"4562_CR22","doi-asserted-by":"publisher","first-page":"e528","DOI":"10.1136\/bmjspcare-2022-003642","volume":"13","author":"A Javan Biparva","year":"2024","unstructured":"Javan Biparva A, Raoofi S, Rafiei S, Pashazadeh Kan F, Kazerooni M, Bagheribayati F, et al. Global quality of life in breast cancer: systematic review and meta-analysis. BMJ Support Palliat Care. 2024;13(e3):e528\u201336. https:\/\/doi.org\/10.1136\/bmjspcare-2022-003642.","journal-title":"BMJ Support Palliat Care"},{"key":"4562_CR23","doi-asserted-by":"publisher","first-page":"2061","DOI":"10.3390\/healthcare13162061","volume":"13","author":"P Kara\u00e7in","year":"2025","unstructured":"Kara\u00e7in P, K\u00fc\u00e7\u00fck\u015fahin \u0130. Sexual Dysfunction in Breast Cancer Survivors: The Role of Clinical, Hormonal, and Psychosocial Factors. Healthcare. 2025;13:2061. https:\/\/doi.org\/10.3390\/healthcare13162061.","journal-title":"Healthcare"},{"issue":"1","key":"4562_CR24","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1111\/j.1743-6109.2010.02034.x","volume":"8","author":"M Panjari","year":"2011","unstructured":"Panjari M, Bell RJ, Davis SR. Sexual function after breast cancer. J Sex Med. 2011;8(1):294\u2013302. https:\/\/doi.org\/10.1111\/j.1743-6109.2010.02034.x.","journal-title":"J Sex Med"},{"issue":"3","key":"4562_CR25","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1007\/s10549-023-07021-y","volume":"201","author":"SK Smedsland","year":"2023","unstructured":"Smedsland SK, Vandraas KF, Falk RS, Horn J, Reidunsdatter RJ, Kiserud CE, et al. Sexual health in long-term breast cancer survivors: a comparison with female population controls from the HUNT study. Breast Cancer Res Treat. 2023;201(3):479\u201388. https:\/\/doi.org\/10.1007\/s10549-023-07021-y.","journal-title":"Breast Cancer Res Treat"},{"issue":"10","key":"4562_CR26","doi-asserted-by":"publisher","first-page":"e47384","DOI":"10.7759\/cureus.47384","volume":"15","author":"SA Salati","year":"2023","unstructured":"Salati SA, Alsulaim L, Alharbi MH, Alharbi NH, Alsenaid TM, Alaodah SA, et al. Postmastectomy Pain Syndrome: Narrative Rev Cureus. 2023;15(10):e47384. https:\/\/doi.org\/10.7759\/cureus.47384.","journal-title":"Postmastectomy Pain Syndrome: Narrative Rev Cureus"},{"issue":"28","key":"4562_CR27","doi-asserted-by":"publisher","first-page":"3325","DOI":"10.1200\/JCO.20.01399","volume":"38","author":"CL Loprinzi","year":"2020","unstructured":"Loprinzi CL, Lacchetti C, Bleeker J, Cavaletti G, Chauhan C, Hertz DL, et al. Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy in Survivors of Adult Cancers: ASCO Guideline Update. J Clin Oncol. 2020;38(28):3325\u201348. https:\/\/doi.org\/10.1200\/JCO.20.01399.","journal-title":"J Clin Oncol"},{"key":"4562_CR28","doi-asserted-by":"publisher","first-page":"103898","DOI":"10.1016\/j.critrevonc.2022.103898","volume":"181","author":"K Bae","year":"2023","unstructured":"Bae K, Lamoury G, Carroll S, Morgia M, Lim S, Baron-Hay S, et al. Comparison of the clinical effectiveness of treatments for aromatase inhibitor-induced arthralgia in breast cancer patients: a systematic review with network meta-analysis. Crit Rev Oncol Hematol. 2023;181:103898. https:\/\/doi.org\/10.1016\/j.critrevonc.2022.103898.","journal-title":"Crit Rev Oncol Hematol"},{"issue":"6","key":"4562_CR29","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1080\/0284186X.2023.2224052","volume":"62","author":"K Vandraas","year":"2023","unstructured":"Vandraas K, Reinertsen KV, Smedsland S, B\u00f8hn S, Kiserud C, Falk RS, et al. Fear of cancer recurrence eight years after early-stage breast cancer \u2013 results from a national survey. Acta Oncol. 2023;62(6):635\u201341. https:\/\/doi.org\/10.1080\/0284186X.2023.2224052.","journal-title":"Acta Oncol"},{"issue":"11","key":"4562_CR30","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.1016\/j.annonc.2022.07.1941","volume":"33","author":"I Vaz-Luis","year":"2022","unstructured":"Vaz-Luis I, Masiero M, Cavaletti G, Cervantes A, Chlebowski RT, Curigliano G, et al. ESMO Expert Consensus Statements on Cancer Survivorship: promoting high-quality survivorship care and research in Europe. Ann Oncol. 2022;33(11):1119\u201333. https:\/\/doi.org\/10.1016\/j.annonc.2022.07.1941.","journal-title":"Ann Oncol"},{"issue":"11","key":"4562_CR31","doi-asserted-by":"publisher","first-page":"3745","DOI":"10.26355\/eurrev_202406_36379","volume":"28","author":"M Milovic","year":"2024","unstructured":"Milovic M, Tamas T, Kolarov Bjelobrk I, Crnobrnja V, Stojsic Milosavljevic A, Paut Kusturica M. Health-related quality of life in different stages of breast cancer in Serbia. Eur Rev Med Pharmacol Sci. 2024;28(11):3745\u201351. https:\/\/doi.org\/10.26355\/eurrev_202406_36379.","journal-title":"Eur Rev Med Pharmacol Sci"},{"issue":"9","key":"4562_CR32","doi-asserted-by":"publisher","first-page":"4035","DOI":"10.1007\/s00520-016-3217-z","volume":"24","author":"C Ecclestone","year":"2016","unstructured":"Ecclestone C, Chow R, Pulenzas N, Zhang L, Leahey A, Hamer J, et al. Quality of life and symptom burden in patients with metastatic breast cancer. Support Care Cancer. 2016;24(9):4035\u201343. https:\/\/doi.org\/10.1007\/s00520-016-3217-z.","journal-title":"Support Care Cancer"},{"issue":"5","key":"4562_CR33","doi-asserted-by":"publisher","first-page":"450","DOI":"10.6004\/jnccn.2023.0026","volume":"21","author":"MB Riba","year":"2023","unstructured":"Riba MB, Donovan KA, Ahmed K, Andersen B, Braun I, Breitbart WS, et al. NCCN Guidelines\u00ae Insights: Distress Management, Version 2.2023. J Natl Compr Canc Netw. 2023;21(5):450\u20137. https:\/\/doi.org\/10.6004\/jnccn.2023.0026.","journal-title":"J Natl Compr Canc Netw"},{"issue":"18","key":"4562_CR34","doi-asserted-by":"publisher","first-page":"3426","DOI":"10.1200\/JCO.23.00293","volume":"41","author":"BL Andersen","year":"2023","unstructured":"Andersen BL, Lacchetti C, Ashing KT, Berek JS, Berman BS, Bolte S, et al. Management of Anxiety and Depression in Adult Survivors of Cancer: ASCO Guideline Update. J Clin Oncol. 2023;41(18):3426\u201353. https:\/\/doi.org\/10.1200\/JCO.23.00293.","journal-title":"J Clin Oncol"},{"issue":"9","key":"4562_CR35","doi-asserted-by":"publisher","first-page":"878","DOI":"10.1016\/j.annonc.2022.04.007","volume":"33","author":"M Di Maio","year":"2022","unstructured":"Di Maio M, Basch E, Denis F, Fallowfield LJ, Ganz PA, Howell D, et al. ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org. The role of patient-reported outcome measures in the continuum of cancer clinical care: ESMO Clinical Practice Guideline. Ann Oncol. 2022;33(9):878\u201392. https:\/\/doi.org\/10.1016\/j.annonc.2022.04.007.","journal-title":"Ann Oncol"},{"key":"4562_CR36","unstructured":"Rubio I, Maravic Z. Time to Accelerate: The Use of Patient-Reported Outcome Measures in European Oncology. Brussels: European Cancer Organisation; 2024. Available from: https:\/\/www.europeancancer.org\/download-file\/1353.html. Accessed 2026 Apr 8."},{"issue":"7","key":"4562_CR37","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1200\/JCO.20.02015","volume":"39","author":"K Absolom","year":"2021","unstructured":"Absolom K, Warrington L, Hudson E, Hewison J, Morris C, Holch P, et al. Phase III Randomized Controlled Trial of eRAPID: eHealth Intervention During Chemotherapy. J Clin Oncol. 2021;39(7):734\u201347. https:\/\/doi.org\/10.1200\/JCO.20.02015.","journal-title":"J Clin Oncol"},{"key":"4562_CR38","doi-asserted-by":"publisher","unstructured":"Maguire R, McCann L, Kotronoulas G, Kearney N, Ream E, Armes J et al. Real time remote symptom monitoring during chemotherapy for cancer: European multicentre randomised controlled trial (eSMART). BMJ. 2021;374:n1647. https:\/\/doi.org\/10.1136\/bmj.n1647. Erratum in: BMJ. 2021;374:n2116. doi: 10.1136\/bmj.n2116.","DOI":"10.1136\/bmj.n1647"},{"issue":"3","key":"4562_CR39","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1007\/s11136-015-1207-0","volume":"25","author":"LM Schougaard","year":"2016","unstructured":"Schougaard LM, Larsen LP, Jessen A, Sidenius P, Dorflinger L, de Thurah A, et al. AmbuFlex: tele-patient-reported outcomes (telePRO) as the basis for follow-up in chronic and malignant diseases. Qual Life Res. 2016;25(3):525\u201334. https:\/\/doi.org\/10.1007\/s11136-015-1207-0. Epub 2016 Jan 20.","journal-title":"Qual Life Res"},{"key":"4562_CR40","doi-asserted-by":"publisher","first-page":"101005","DOI":"10.1016\/j.lanepe.2024.101005","volume":"44","author":"MA Franzoi","year":"2024","unstructured":"Franzoi MA, Ferreira AR, Lemaire A, Rodriguez J, Grosjean J, Ribeiro JM, et al. Implementation of a remote symptom monitoring pathway in oncology care: analysis of real-world experience across 33 cancer centres in France and Belgium. Lancet Reg Health Eur. 2024;44:101005. https:\/\/doi.org\/10.1016\/j.lanepe.2024.101005.","journal-title":"Lancet Reg Health Eur"},{"issue":"2","key":"4562_CR41","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/S1470-2045(25)00679-5","volume":"27","author":"LM Wintner","year":"2026","unstructured":"Wintner LM, Sztankay M, Abdel-Razeq H, Hamdan-Mansour R, Caocci G, Mouillet G, et al. EORTC Quality of Life Group. Inter-rater reliability of CTCAE assessments with or without EORTC patient-reported outcome data in a mixed cancer population: a multinational, open-label, randomised controlled trial. Lancet Oncol. 2026;27(2):233\u201342. https:\/\/doi.org\/10.1016\/S1470-2045(25)00679-5.","journal-title":"Lancet Oncol"},{"issue":"17","key":"4562_CR42","doi-asserted-by":"publisher","first-page":"2038","DOI":"10.1200\/JCO.23.01447","volume":"42","author":"L Saltb\u00e6k","year":"2024","unstructured":"Saltb\u00e6k L, Bidstrup PE, Karlsen RV, H\u00f8eg BL, Horsboel TA, Belmonte F, et al. Nurse-Led Individualized Follow-Up Versus Regular Physician-Led Visits After Early Breast Cancer (MyHealth): A Phase III Randomized, Controlled Trial. J Clin Oncol. 2024;42(17):2038\u201349. https:\/\/doi.org\/10.1200\/JCO.23.01447.","journal-title":"J Clin Oncol"},{"issue":"7","key":"4562_CR43","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.1016\/j.ejca.2010.12.003","volume":"47","author":"ML Kimman","year":"2011","unstructured":"Kimman ML, Dirksen CD, Voogd AC, Falger P, Gijsen BC, Thuring M, et al. Nurse-led telephone follow-up and an educational group programme after breast cancer treatment: results of a 2 \u00d7 2 randomised controlled trial. Eur J Cancer. 2011;47(7):1027\u201336. https:\/\/doi.org\/10.1016\/j.ejca.2010.12.003.","journal-title":"Eur J Cancer"},{"key":"4562_CR44","unstructured":"EORTC Quality of Life Group. Breast Cancer (update of QLQ-BR23): QLQ-BR42 [Internet]. Available from: https:\/\/qol.eortc.org\/questionnaire\/update-qlq-br23\/. Accessed 2025 Dec 25."},{"key":"4562_CR45","doi-asserted-by":"publisher","unstructured":"Runowicz CD, Leach CR, Henry NL, Henry KS, Mackey HT, Cowens-Alvarado RL et al. American Cancer Society\/American Society of Clinical Oncology Breast Cancer Survivorship Care Guideline. CA Cancer J Clin 2016 Jan-Feb;66(1):43\u201373. https:\/\/doi.org\/10.3322\/caac.21319.","DOI":"10.3322\/caac.21319"}],"container-title":["BMC Women's Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12905-026-04562-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12905-026-04562-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12905-026-04562-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T23:23:20Z","timestamp":1785713000000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12905-026-04562-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,26]]},"references-count":45,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["4562"],"URL":"https:\/\/doi.org\/10.1186\/s12905-026-04562-4","relation":{},"ISSN":["1472-6874"],"issn-type":[{"value":"1472-6874","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,26]]},"assertion":[{"value":"11 February 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The study was conducted in accordance with the Declaration of Helsinki and approved by the Ethics Committee of the University Hospital Centre Split and the Ethics Committee of University Hospital Centre Sestre milosrdnice, Zagreb.All participants received written information about the study and provided written informed consent prior to participation. No personal identifiers were collected, and all data were analysed anonymously.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"388"}}