{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T01:19:23Z","timestamp":1789867163972,"version":"4.0.1"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Complement Altern Med"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s12906-017-1563-0","type":"journal-article","created":{"date-parts":[[2017,3,8]],"date-time":"2017-03-08T11:13:57Z","timestamp":1488971637000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Evaluation of the antimycobacterial activity of crude extracts and solvent fractions of selected Ethiopian medicinal plants"],"prefix":"10.1186","volume":"17","author":[{"given":"Wubayehu","family":"Kahaliw","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abraham","family":"Aseffa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markos","family":"Abebe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mekonen","family":"Teferi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ephrem","family":"Engidawork","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,3,8]]},"reference":[{"key":"1563_CR1","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1471-2180-6-23","volume":"6","author":"K Brudey","year":"2006","unstructured":"Brudey K, Driscoll JR, Rigouts L. Mycobacterium Tuberculosis complex genetic diversity: mining the fourth international spoligotyping database (SpolDB4) for classification. BMC Microbiol. 2006;6:23.","journal-title":"BMC Microbiol"},{"key":"1563_CR2","volume-title":"World TB report 2001. Global tuberculosis control: surveillance, planning, financing","author":"WHO","year":"2002","unstructured":"WHO. World TB report 2001. Global tuberculosis control: surveillance, planning, financing. Geneva: World Health Organization; 2002."},{"key":"1563_CR3","volume-title":"Global tuberculosis report 2014","author":"WHO","year":"2015","unstructured":"WHO. Global tuberculosis report 2014. Geneva: World Health Organization; 2015."},{"issue":"3","key":"1563_CR4","first-page":"771","volume":"2","author":"RM Mariita","year":"2010","unstructured":"Mariita RM, Okemo PO, Orodho JA, Kirimuhuzya C, Otieno JN, Magadula JJ. Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea causing bacteria and Candida Albicans. IJPT. 2010;2(3):771\u201391.","journal-title":"IJPT"},{"key":"1563_CR5","doi-asserted-by":"crossref","unstructured":"Raiz M, Zia-Ul Haq M, Saad B. Anthocyanins and human health: Biomolecular and Therapeutic Aspects. Switzerland: Springer International Publishing AG; 2016.","DOI":"10.1007\/978-3-319-26456-1"},{"key":"1563_CR6","unstructured":"Hamisi MM, Vitus AN, Andrew M. Anti\u2010TB Natural Products in Tanzanian Medicinal Plants. 2009. http:\/\/www.nimr.or.tz\/ Anti\u2010TB Natural Products in Tanzanian Medicinal Plants. Accessed 31 Oct 2015."},{"issue":"2","key":"1563_CR7","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1351\/pac199870020365","volume":"70","author":"LA Mitscher","year":"1998","unstructured":"Mitscher LA, Baker WR. A search for novel chemotherapy against tuberculosis amongst natural products. Pure Appl Chem. 1998;70(2):365\u2013271.","journal-title":"Pure Appl Chem"},{"issue":"3","key":"1563_CR8","first-page":"101","volume":"8","author":"G Andualem","year":"2014","unstructured":"Andualem G, Umar S, Getnet F, Tekewe A, Alemayehu H, Kebede N. Antimicrobial and phytochemical screening of methanol extracts of three medicinal plants in Ethiopia. Adv Biol Res. 2014;8(3):101\u20136.","journal-title":"Adv Biol Res"},{"issue":"6","key":"1563_CR9","first-page":"1217","volume":"31","author":"E Balcha","year":"2014","unstructured":"Balcha E, Mengiste B, Gebrelibanos M, Worku I, Ameni G. Evaluation of In-vitro Anti-mycobacterial Activity of Selected Medicinal Plants in Mekelle, Ethiopia. World Appl Sci J. 2014;31(6):1217\u201320.","journal-title":"World Appl Sci J"},{"key":"1563_CR10","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.4948","author":"A Endale","year":"2013","unstructured":"Endale A, Bisrat D, Animut A, Bucar F, Asres K. In vivo antimalarial activity of a Labdane Diterpenoid from the leaves of Otostegia integrifolia benth. Phytother Res. 2013. doi: 10.1002\/ptr.4948 .","journal-title":"Phytother Res"},{"key":"1563_CR11","unstructured":"Getahun A. Some Common Medicinal and Poisonous Plants Used in Ethiopian Folk Medicine. 1976. http:\/\/www.mrc.ac.za\/ . Accessed 14 Dec 2014."},{"key":"1563_CR12","volume-title":"Guide for the care and use of laboratory animals","author":"Institute for Laboratory Animal Research (ILAR)","year":"2001","unstructured":"Institute for Laboratory Animal Research (ILAR). Guide for the care and use of laboratory animals. Washington: National Academy Press; 2001."},{"issue":"11","key":"1563_CR13","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.5897\/AJB08.438","volume":"7","author":"A Mann","year":"2008","unstructured":"Mann A, Amupitan JO, Oyewale AO, Okogun JI, Ibrahim K, Oladosu P, Lawson L, Olajide I, Nnamdi A. Evaluation of in vitro antimycobacterial activity of Nigerian plants used for treatment of respiratory diseases. Afr J Biotechnol. 2008;7(11):1630\u20136.","journal-title":"Afr J Biotechnol"},{"key":"1563_CR14","unstructured":"OECD guideline for testing of chemicals. Acute Oral Toxicity\u2013 Acute Toxic Class Method. 2001."},{"issue":"2","key":"1563_CR15","first-page":"188","volume":"3","author":"R Gomez-Flores","year":"2008","unstructured":"Gomez-Flores R, Arzate-Quintana C, Quintanilla-Licea R, Tamez-Guerra P, Tamez-Guerra R, Monreal-Cuevas E, Rodr\u00edguez-Padilla C. Antimicrobial Activity of Persea americana Mill (Lauraceae) and Gymnosperma glutinosum (Spreng.) (Asteraceae) leaf extracts and active fractions against Mycobacterium tuberculosis. Am-Euras J Sci Res. 2008;3(2):188\u201394.","journal-title":"Am-Euras J Sci Res"},{"issue":"9","key":"1563_CR16","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.5251\/abjna.2011.2.9.1270.1272","volume":"2","author":"JB Nvau","year":"2011","unstructured":"Nvau JB, Oladosu PO, Orishadipe AT. Antimycobacterial evaluation of some medicinal plants used in Plateau State of Nigeria for the Treatment of Tuberculosis. Agric Biol J N Am. 2011;2(9):1270\u20132.","journal-title":"Agric Biol J N Am"},{"key":"1563_CR17","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.jep.2011.04.062","volume":"137","author":"L Xuan","year":"2011","unstructured":"Xuan L, David P, Jose AA, Begona G, Silva M, Aida D, Elsa A, Maria-Jose UF. Antimycobacterial evaluation and preliminary phytochemical investigation of selected medicinal plants traditionally used in Mozambique. J Ethnopharmacol. 2011;137:114\u201320.","journal-title":"J Ethnopharmacol"},{"key":"1563_CR18","doi-asserted-by":"crossref","first-page":"8471","DOI":"10.3390\/molecules17078471","volume":"17","author":"CE Patricia","year":"2012","unstructured":"Patricia CE, Juan MJ, Elvira G, Noem\u00ed W, Mar\u00eda Y, Mar\u00edadel R. Antimycobacterial activity of constituents from Foeniculum Vulgare Var. Dulce Grown in Mexico. Molecules. 2012;17:8471\u201382.","journal-title":"Molecules"},{"issue":"3","key":"1563_CR19","first-page":"863","volume":"4","author":"R Deepthi","year":"2012","unstructured":"Deepthi R, Junise V, Shibin SS, Rajesh S. Isolation, identification and Antimycobacterial evaluation of Piperine from Piper longu. Pharm Lett. 2012;4(3):863\u20138.","journal-title":"Pharm Lett"},{"issue":"4","key":"1563_CR20","first-page":"81","volume":"3","author":"SS Nair","year":"2015","unstructured":"Nair SS, Pharande RR, Bannalikar AS, Mukne AP. In vitro anti-mycobacterial activity of acetone extract of glycyrrhiza glabra. J Pharm Pharmacogn Res. 2015;3(4):81.","journal-title":"J Pharm Pharmacogn Res"},{"key":"1563_CR21","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1016\/j.phytochem.2004.03.012","volume":"65","author":"H Tesso","year":"2004","unstructured":"Tesso H, K\u00f6nig A. Terpenes from Otostegia integrifolia. Phytochemistry. 2004;65:2057\u201362.","journal-title":"Phytochemistry"},{"issue":"12","key":"1563_CR22","first-page":"150","volume":"6","author":"AB Yusuf","year":"2012","unstructured":"Yusuf AB, Umar IA, Nok AJ. Effects of methanol extract of vernonia amygdalina leaf on survival and some biochemical parameters in acute trypanosoma brucei infection. Afr J Biochem Res. 2012;6(12):150\u20138.","journal-title":"Afr J Biochem Res"},{"key":"1563_CR23","unstructured":"Orwa C, Mutua A, Kindt R, Jamnadass R, Simons A. Agroforestree Database: a Tree Reference and Selection Guide Version 4.0. 2009. http:\/\/www.kemri.org\/ . Accessed 29 Oct 2015."},{"issue":"15","key":"1563_CR24","first-page":"1517","volume":"4","author":"MF Tolo","year":"2010","unstructured":"Tolo MF, Rukung WG, Muli WF, Ochora MJ, Irungu NB, Muthaura NC, Wanjiku KC, Mungai MG, Quang N, Hashimoto K, Asakawa Y. The antiviral activity of compounds isolated from Kenyan Carissa edulis (Forssk.) vahl. JMPR. 2010;4(15):1517\u201322.","journal-title":"JMPR"},{"key":"1563_CR25","volume-title":"Dominican medicinal plants: a guide for health care providers","year":"2010","unstructured":"Yukes JE, Balick MJ, editors. Dominican medicinal plants: a guide for health care providers. 2nd ed. New York: The New York Botanical Garden; 2010.","edition":"2"},{"key":"1563_CR26","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1093\/jac\/dkm207","volume":"60","author":"NK Taneja","year":"2007","unstructured":"Taneja NK, Tyagi JS. Resazurin reduction assays for screening of anti- tubercular compounds against dormant and actively growing Mycobacterium tuberculosis, Mycobacterium bovis BCG and Mycobacterium smegmatis. J Antimicrob Chemother. 2007;60:288\u201393.","journal-title":"J Antimicrob Chemother"},{"key":"1563_CR27","volume-title":"Performance standards for antimicrobial susceptibility testing; twenty-fourth informational supplement. CLSI document M100-524","author":"CLSI","year":"2014","unstructured":"CLSI. Performance standards for antimicrobial susceptibility testing; twenty-fourth informational supplement. CLSI document M100-524. Wayne: Clinical and laboratory standards institute; 2014."},{"key":"1563_CR28","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.jep.2004.07.011","volume":"95","author":"F Tosun","year":"2004","unstructured":"Tosun F, Aky\u00fcz Kizilay C, Sener B, Vural M, Palittapongarnpim P. Antimycobacterial screening of some Turkish plants. J Ethnopharmacol. 2004;95:273\u20135.","journal-title":"J Ethnopharmacol"},{"key":"1563_CR29","first-page":"5","volume":"1","author":"CT Higuchi","year":"2008","unstructured":"Higuchi CT, Pavan FR, Sato DN. Apolar compounds with antitubercular activity. Compl Alt Med. 2008;1:5.","journal-title":"Compl Alt Med"},{"key":"1563_CR30","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1590\/S1517-83822010000200001","volume":"41","author":"JG S\u00e1nchez","year":"2010","unstructured":"S\u00e1nchez JG, Kouznetsov VV. Anti-mycobacterial susceptibility testing methods for natural products research. Braz J Microbiol. 2010;41:270\u20137.","journal-title":"Braz J Microbiol"},{"issue":"3","key":"1563_CR31","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.jep.2004.10.006","volume":"96","author":"M Billo","year":"2005","unstructured":"Billo M, Cabalion P, Waikredre J, Fourneau C, Bouttier S, Hocquemiller R, Fournet A. Screening of some New Caledonian and Vanuatu medicinal plants for anti-mycobacterial activity. J Ethnopharmacol. 2005;96(3):569\u201375.","journal-title":"J Ethnopharmacol"},{"key":"1563_CR32","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.jep.2006.11.033","volume":"111","author":"A Jim\u00e9nez-Arellanes","year":"2007","unstructured":"Jim\u00e9nez-Arellanes A, Meckes M, Torres J, Luna-Herrera J. Anti-mycobacterial Triterpenoids from Lantana hispida (Verbenaceae). J Ethnopharmacol. 2007;111:202\u20135.","journal-title":"J Ethnopharmacol"},{"key":"1563_CR33","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0378-8741(01)00350-6","volume":"79","author":"SM Newton","year":"2002","unstructured":"Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW. The evaluation of forty-three plant species for In vitro Antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis. J Ethnopharmacol. 2002;79:57\u201367.","journal-title":"J Ethnopharmacol"},{"key":"1563_CR34","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.jep.2006.12.031","volume":"110","author":"R Gautam","year":"2007","unstructured":"Gautam R, Saklani A, Jachak SM. Indian medicinal plants as a source of Antimycobacterial agents. J Ethnopharmacol. 2007;110:200\u201334.","journal-title":"J Ethnopharmacol"}],"container-title":["BMC Complementary and Alternative Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12906-017-1563-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T09:24:59Z","timestamp":1568885099000},"score":1,"resource":{"primary":{"URL":"http:\/\/bmccomplementalternmed.biomedcentral.com\/articles\/10.1186\/s12906-017-1563-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,8]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["1563"],"URL":"https:\/\/doi.org\/10.1186\/s12906-017-1563-0","relation":{},"ISSN":["1472-6882"],"issn-type":[{"value":"1472-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,8]]},"article-number":"143"}}