{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T05:33:31Z","timestamp":1759815211430,"version":"3.37.3"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["102-2314-B-214-003-MY3"],"award-info":[{"award-number":["102-2314-B-214-003-MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004738","name":"E-Da Hospital","doi-asserted-by":"publisher","award":["EDAHP105031","EDAHP105049"],"award-info":[{"award-number":["EDAHP105031","EDAHP105049"]}],"id":[{"id":"10.13039\/501100004738","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Complement Altern Med"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s12906-017-1752-x","type":"journal-article","created":{"date-parts":[[2017,5,8]],"date-time":"2017-05-08T09:23:25Z","timestamp":1494235405000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Mechanism of resveratrol-induced relaxation in the human gallbladder"],"prefix":"10.1186","volume":"17","author":[{"given":"Ching-Chung","family":"Tsai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming-Che","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shu-Leei","family":"Tey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ching-Wen","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shih-Che","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,5,8]]},"reference":[{"key":"1752_CR1","doi-asserted-by":"publisher","first-page":"141","DOI":"10.3389\/fphar.2012.00141","volume":"3","author":"B Catalgol","year":"2012","unstructured":"Catalgol B, Batirel S, Taga Y, Ozer NK. Resveratrol: French paradox revisited. Front Pharmacol. 2012;3:141.","journal-title":"Front Pharmacol"},{"key":"1752_CR2","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1007\/BF01201331","volume":"196","author":"FZ Mattivi","year":"1993","unstructured":"Mattivi FZ. Solid phase extraction of trans-resveratrol from wines for HPLC analysis. Lebensm Unters Forsch. 1993;196:522\u20135.","journal-title":"Lebensm Unters Forsch"},{"key":"1752_CR3","first-page":"635","volume":"4","author":"RF Guerrero","year":"2009","unstructured":"Guerrero RF, Garc\u00eda-Parrilla MC, Puertas B, Cantos-Villar E. Wine, resveratrol and health: a review. Nat Prod Commun. 2009;4:635\u201358.","journal-title":"Nat Prod Commun"},{"key":"1752_CR4","doi-asserted-by":"publisher","unstructured":"Zordoky BN, Robertson IM, Dyck JR. Preclinical and clinical evidence for the role of resveratrol in the treatment of cardiovascular diseases. Biochim Biophys Acta. 2015;1852:1155\u201377.","DOI":"10.1016\/j.bbadis.2014.10.016"},{"key":"1752_CR5","doi-asserted-by":"publisher","DOI":"10.3390\/nu8050250","volume":"8","author":"D Bonnefont-Rousselot","year":"2016","unstructured":"Bonnefont-Rousselot D. Resveratrol and Cardiovascular Diseases. Nutrients. 2016;8:E250.","journal-title":"Nutrients"},{"key":"1752_CR6","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1016\/j.nut.2015.08.017","volume":"32","author":"GT Diaz-Gerevini","year":"2016","unstructured":"Diaz-Gerevini GT, Repossi G, Dain A, Tarres MC, Das UN, Eynard AR. Beneficial action of resveratrol: how and why? Nutrition. 2016;32:174\u20138.","journal-title":"Nutrition"},{"key":"1752_CR7","doi-asserted-by":"publisher","first-page":"1370","DOI":"10.1111\/j.1365-2036.2012.05115.x","volume":"35","author":"A Colli","year":"2012","unstructured":"Colli A, Conte D, Valle SD, Sciola V, Fraquelli M. Meta-analysis: nonsteroidal anti-inflammatory drugs in biliary colic. Aliment Pharmacol Ther. 2012;35:1370\u20138.","journal-title":"Aliment Pharmacol Ther"},{"key":"1752_CR8","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/S0736-4679(02)00524-3","volume":"23","author":"SO Henderson","year":"2002","unstructured":"Henderson SO, Swadron S, Newton E. Comparison of intravenous ketorolac and meperidine in the treatment of biliary colic. J Emerg Med. 2002;23:237\u201341.","journal-title":"J Emerg Med"},{"key":"1752_CR9","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.amjopharm.2006.03.008","volume":"4","author":"J Ness","year":"2006","unstructured":"Ness J, Hoth A, Barnett MJ, Shorr RI, Kaboli PJ. Anticholinergic medications in community-dwelling older veterans: prevalence of anticholinergic symptoms, symptom burden, and adverse drug events. Am J Geriatr Pharmacother. 2006;4:42\u201351.","journal-title":"Am J Geriatr Pharmacother"},{"key":"1752_CR10","doi-asserted-by":"publisher","unstructured":"Kline LW, Karpinski E. The resveratrol-induced relaxation of cholecystokinin octapeptide- or KCl-induced tension in male guinea pig gallbladder strips is mediated through L-type Ca2+ channels. J Neurogastroenterol Motil. 2015;21:62\u20138.","DOI":"10.5056\/jnm14093"},{"key":"1752_CR11","doi-asserted-by":"publisher","first-page":"4955","DOI":"10.3748\/wjg.14.4955","volume":"14","author":"LD Wang","year":"2008","unstructured":"Wang LD, Qiu XQ, Tian ZF, Zhang YF, Li HF. Inhibitory effects of genistein and resveratrol on guinea pig gallbladder contractility in vitro. World J Gastroenterol. 2008;14:4955\u201360.","journal-title":"World J Gastroenterol"},{"key":"1752_CR12","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1111\/jphp.12041","volume":"65","author":"F Jing","year":"2013","unstructured":"Jing F, Liu M, Yang N, Liu Y, Li X, Li JJ. Relaxant effect of chloroquine in rat ileum: possible involvement of nitric oxide and BKCa. Pharm Pharmacol. 2013;65:847\u201354.","journal-title":"Pharm Pharmacol"},{"key":"1752_CR13","doi-asserted-by":"publisher","unstructured":"Huang SC. Endothelin A receptors mediate relaxation of guinea pig internal anal sphincter through cGMP pathway. Neurogastroenterol Motil. 2010;22:1009\u201316.","DOI":"10.1111\/j.1365-2982.2010.01513.x"},{"key":"1752_CR14","doi-asserted-by":"publisher","first-page":"2363","DOI":"10.1021\/bi00060a030","volume":"32","author":"KM Giangiacomo","year":"1993","unstructured":"Giangiacomo KM, Sugg EE, Garcia-Calvo M, Leonard RJ, McManus OB, Kaczorowski GJ, Garcia ML. Synthetic charybdotoxin-iberiotoxin chimeric peptides define toxin binding sites on calcium-activated and voltage-dependent potassium channels. Biochemistry. 1993;32:2363\u201370.","journal-title":"Biochemistry"},{"key":"1752_CR15","doi-asserted-by":"publisher","first-page":"788","DOI":"10.1124\/mol.65.3.788","volume":"65","author":"OH Wittekindt","year":"2004","unstructured":"Wittekindt OH, Visan V, Tomita H, Imtiaz F, Gargus JJ, Lehmann-Horn F, Grissmer S, Morris-Rosendahl DJ. An apamin- and scyllatoxin-insensitive isoform of the human SK3 channel. Mol Pharmacol. 2004;65:788\u2013801.","journal-title":"Mol Pharmacol"},{"key":"1752_CR16","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1016\/j.pneurobio.2010.03.002","volume":"91","author":"KL Weatherall","year":"2010","unstructured":"Weatherall KL, Goodchild SJ, Jane DE, Marrion NV. Small conductance calcium-activated potassium channels: from structure to function. Prog Neurobiol. 2010;91:242\u201355.","journal-title":"Prog Neurobiol"},{"key":"1752_CR17","doi-asserted-by":"publisher","first-page":"G1322","DOI":"10.1152\/ajpgi.00325.2012","volume":"303","author":"J Zhang","year":"2012","unstructured":"Zhang J, Halm ST, Halm DR. Role of the BK channel (KCa1.1) during activation of electrogenic K+ secretion in guinea pig distal colon. Am J Physiol Gastrointest Liver Physiol. 2012;303:G1322\u201334.","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"1752_CR18","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1111\/j.1472-8206.2009.00761.x","volume":"24","author":"NM Matsuda","year":"2010","unstructured":"Matsuda NM, Miller SM. Non-adrenergic non-cholinergic inhibition of gastrointestinal smooth muscle and its intracellular mechanism(s). Fundam Clin Pharmacol. 2010;24:261\u20138.","journal-title":"Fundam Clin Pharmacol"},{"key":"1752_CR19","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1111\/j.1742-7843.2006.pto_531.x","volume":"99","author":"A Novakovic","year":"2006","unstructured":"Novakovic A, Bukarica LG, Kanjuh V, Heinle H. Potassium channels-mediated vasorelaxation of rat aorta induced by resveratrol. Basic Clin Pharmacol Toxicol. 2006;99:360\u20134.","journal-title":"Basic Clin Pharmacol Toxicol"},{"key":"1752_CR20","doi-asserted-by":"publisher","first-page":"4232","DOI":"10.1167\/iovs.07-0094","volume":"48","author":"T Nagaoka","year":"2007","unstructured":"Nagaoka T, Hein TW, Yoshida A, Kuo L. Resveratrol, a component of red wine, elicits dilation of isolated porcine retinal arterioles: role of nitric oxide and potassium channels. Invest Ophthalmol Vis Sci. 2007;48:4232\u20139.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1752_CR21","first-page":"720386","volume":"2014","author":"C Pullen","year":"2014","unstructured":"Pullen C, Coulson FR, Fenning A. Effects of resveratrol and nebivolol on isolated vascular and cardiac tissues from young rats. Adv Pharmacol Sci. 2014;2014:720386.","journal-title":"Adv Pharmacol Sci"},{"key":"1752_CR22","doi-asserted-by":"publisher","first-page":"8512","DOI":"10.1021\/bi00084a017","volume":"32","author":"ES Furfine","year":"1993","unstructured":"Furfine ES, Harmon MF, Paith JE, Garvey EP. Selective inhibition of constitutive nitric oxide synthase by L-NG-nitroarginine. Biochemistry. 1993;32:8512\u20137.","journal-title":"Biochemistry"},{"key":"1752_CR23","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1006\/abbi.1994.1232","volume":"311","author":"EP Garvey","year":"1994","unstructured":"Garvey EP, Tuttle JV, Covington K, Merrill BM, Wood ER, Baylis SA, Charles IG. Purification and characterization of the constitutive nitric oxide synthase from human placenta. Arch Biochem Biophys. 1994;311:235\u201341.","journal-title":"Arch Biochem Biophys"},{"key":"1752_CR24","doi-asserted-by":"crossref","first-page":"C1409","DOI":"10.1152\/ajpcell.1998.275.6.C1409","volume":"275","author":"KS Murthy","year":"1998","unstructured":"Murthy KS, Teng B, Jin J, Makhlouf GM. G protein-dependent activation of smooth muscle eNOS via natriuretic peptide clearance receptor. Am J Phys. 1998;275:C1409\u201316.","journal-title":"Am J Phys"},{"key":"1752_CR25","first-page":"G342","volume":"275","author":"B Teng","year":"1998","unstructured":"Teng B, Murthy KS, Kuemmerle JF, Grider JR, Sase K, Michel T, Makhlouf GM. Expression of endothelial nitric oxide synthase in human and rabbit gastrointestinal smooth muscle cells. Am J Phys. 1998;275:G342\u201351.","journal-title":"Am J Phys"},{"key":"1752_CR26","first-page":"276","volume-title":"Yamada's textbook of gastroenterology","author":"GM Makhlouf","year":"2016","unstructured":"Makhlouf GM, Murthy KS. Smooth muscle of the gut. In: Podolsky DK, Camilleri M, Fitz JG, Kalloo AN, Shanahan F, Wang TC, editors. Yamada's textbook of gastroenterology. Hoboken: Wiley-Blackwell; 2016. p. 276\u20138."},{"key":"1752_CR27","first-page":"a004549","volume":"3","author":"DC Hill-Eubanks","year":"2011","unstructured":"Hill-Eubanks DC, Werner ME, Heppner TJ, Nelson MT. Calcium signaling in smooth muscle. Cold Spring Harb Perspect Biol. 2011;3:a004549.","journal-title":"Cold Spring Harb Perspect Biol"},{"key":"1752_CR28","doi-asserted-by":"publisher","first-page":"1412","DOI":"10.1002\/ptr.5145","volume":"28","author":"D Proti\u0107","year":"2014","unstructured":"Proti\u0107 D, Beleslin-\u010coki\u0107 B, Spremovi\u0107-Ra\u0111enovi\u0107 S, Radunovi\u0107 N, Heinle H, S\u0107epanovi\u0107 R, Gojkovi\u0107 Bukarica L. The different effects of resveratrol and naringenin on isolated human umbilical vein: the role of ATP-sensitive K+ channels. Phytother Res. 2014;28:1412\u20138.","journal-title":"Phytother Res"},{"key":"1752_CR29","doi-asserted-by":"publisher","first-page":"47","DOI":"10.4103\/0973-1296.126658","volume":"10","author":"S Dalaklioglu","year":"2014","unstructured":"Dalaklioglu S, Ozbey G. Role of different types of potassium channels in the relaxation of corpus cavernosum induced by resveratrol. Pharmacogn Mag. 2014;10:47\u201352.","journal-title":"Pharmacogn Mag"}],"container-title":["BMC Complementary and Alternative Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12906-017-1752-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,23]],"date-time":"2019-09-23T16:15:30Z","timestamp":1569255330000},"score":1,"resource":{"primary":{"URL":"http:\/\/bmccomplementalternmed.biomedcentral.com\/articles\/10.1186\/s12906-017-1752-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,8]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["1752"],"URL":"https:\/\/doi.org\/10.1186\/s12906-017-1752-x","relation":{},"ISSN":["1472-6882"],"issn-type":[{"type":"electronic","value":"1472-6882"}],"subject":[],"published":{"date-parts":[[2017,5,8]]},"article-number":"254"}}