{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T12:54:06Z","timestamp":1773752046866,"version":"3.50.1"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Complement Altern Med"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s12906-017-1857-2","type":"journal-article","created":{"date-parts":[[2017,7,14]],"date-time":"2017-07-14T11:09:00Z","timestamp":1500030540000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Xue-fu-Zhu-Yu decoction protects rats against retinal ischemia by downregulation of HIF-1\u03b1 and VEGF via inhibition of RBP2 and PKM2"],"prefix":"10.1186","volume":"17","author":[{"given":"Shu-Qiu","family":"Tan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xue","family":"Geng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorn-Hon","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wynn Hwai-Tzong","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Xiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui-Kang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsiao-Ming","family":"Chao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,7,14]]},"reference":[{"issue":"1","key":"1857_CR1","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.preteyeres.2003.12.001","volume":"23","author":"NN Osborne","year":"2004","unstructured":"Osborne NN, Casson RJ, Wood JP, Chidlow G, Graham M, Melena J. Retinal ischemia: mechanisms of damage and potential therapeutic strategies. Prog Retin Eye Res. 2004;23(1):91\u2013147. doi:\n10.1016\/j.preteyeres.2003.12.001\n\n.","journal-title":"Prog Retin Eye Res"},{"issue":"3","key":"1857_CR2","doi-asserted-by":"publisher","first-page":"238","DOI":"10.3109\/02713683.2010.539760","volume":"36","author":"PH Peng","year":"2011","unstructured":"Peng PH, Chao HM, Juan SH, Chen CF, Liu JH, Ko ML. Pharmacological preconditioning by low dose cobalt protoporphyrin induces heme oxygenase-1 overexpression and alleviates retinal ischemia-reperfusion injury in rats. Curr Eye Res. 2011;36(3):238\u201346. doi:\n10.3109\/02713683.2010.539760\n\n.","journal-title":"Curr Eye Res"},{"issue":"3","key":"1857_CR3","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1142\/S0192415X14500451","volume":"42","author":"HM Chao","year":"2014","unstructured":"Chao HM, Chen IL, Liu JH. S-allyl L-cysteine protects the retina against kainate excitotoxicity in the rat. Am J Chin Med. 2014;42(3):693\u2013708. doi:\n10.1142\/S0192415X14500451\n\n.","journal-title":"Am J Chin Med"},{"issue":"6","key":"1857_CR4","doi-asserted-by":"publisher","first-page":"3360","DOI":"10.1167\/iovs.10-6901","volume":"52","author":"A Wurm","year":"2011","unstructured":"Wurm A, Iandiev I, Uhlmann S, Wiedemann P, Reichenbach A, Bringmann A, et al. Effects of ischemia-reperfusion on physiological properties of M\u00fcller glial cells in the porcine retina. Invest Ophthalmol Vis Sci. 2011;52(6):3360\u20137. doi:\n10.1167\/iovs.10-6901\n\n.","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"4","key":"1857_CR5","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1001\/archopht.122.4.598","volume":"122","author":"MA Zarbin","year":"2004","unstructured":"Zarbin MA. Current concepts in the pathogenesis of age-related macular degeneration. Arch Ophthalmol. 2004;122(4):598\u2013614.","journal-title":"Arch Ophthalmol"},{"issue":"1","key":"1857_CR6","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1007\/s12177-010-9050-6","volume":"3","author":"G H\u00e5kansson","year":"2010","unstructured":"H\u00e5kansson G, Gesslein B, Gustafsson L, Englund-Johansson U, Malmsj\u00f6 M. Hypoxia-inducible factor and vascular endothelial growth factor in the neuroretina and retinal blood vessels after retinal ischemia. J Ocul Biol Dis Infor. 2010;3(1):20\u20139. doi:\n10.1007\/s12177-010-9050-6\n\n.","journal-title":"J Ocul Biol Dis Infor"},{"issue":"5","key":"1857_CR7","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1089\/jop.2010.0063","volume":"26","author":"JH Liu","year":"2010","unstructured":"Liu JH, Wann H, Chen MM, Pan WH, Chen YC, Liu CM, et al. Baicalein significantly protects human retinal pigment epithelium cells against H2 O2 -induced oxidative stress by scavenging reactive oxygen species and downregulating the expression of matrix metalloproteinase-9 and vascular endothelial growth factor. J Ocul Pharmacol Ther. 2010;26(5):421\u20139. doi:\n10.1089\/jop.2010.0063\n\n.","journal-title":"J Ocul Pharmacol Ther"},{"key":"1857_CR8","doi-asserted-by":"publisher","first-page":"2035","DOI":"10.1038\/ncomms3035","volume":"4","author":"L Wang","year":"2013","unstructured":"Wang L, Chang J, Varghese D, Dellinger M, Kumar S, Best AM, et al. A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth. Nat Commun. 2013;4:2035. doi:\n10.1038\/ncomms3035\n\n.","journal-title":"Nat Commun"},{"issue":"5","key":"1857_CR9","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1002\/mc.21988","volume":"53","author":"W Li","year":"2014","unstructured":"Li W, Liu J, Zhao Y. PKM2 inhibitor shikonin suppresses TPA-induced mitochondrial malfunction and proliferation of skin epidermal JB6 cells. Mol Carcinog. 2014 May;53(5):403\u201312. doi:\n10.1002\/mc.21988\n\n.","journal-title":"Mol Carcinog"},{"issue":"17","key":"1857_CR10","doi-asserted-by":"publisher","first-page":"3457","DOI":"10.1002\/jssc.201600083","volume":"39","author":"C Fu","year":"2016","unstructured":"Fu C, Xia Z, Liu Y, Lu H, Zhang Z, Wang Y, et al. Qualitative analysis of major constituents from Xue fu Zhu Yu decoction using ultra high performance liquid chromatography with hybrid ion trap time-of-flight mass spectrometry. J Sep Sci. 2016;39(17):3457\u201368. doi:\n10.1002\/jssc.201600083\n\n.","journal-title":"J Sep Sci"},{"issue":"3","key":"1857_CR11","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1016\/j.jep.2011.01.033","volume":"134","author":"JJ Lee","year":"2011","unstructured":"Lee JJ, Hsu WH, Yen TL, Chang NC, Luo YJ, Hsiao G, et al. Traditional Chinese medicine, Xue-fu-Zhu-Yu decoction, potentiates tissue plasminogen activator against thromboembolic stroke in rats. J Ethnopharmacol. 2011;134(3):824\u201330. doi:\n10.1016\/j.jep.2011.01.033\n\n.","journal-title":"J Ethnopharmacol"},{"issue":"3","key":"1857_CR12","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1016\/j.jep.2014.03.019","volume":"153","author":"YN Zhou","year":"2014","unstructured":"Zhou YN, Sun MY, Mu YP, Yang T, Ning BB, Ren S, et al. Xuefuzhuyu decoction inhibition of angiogenesis attenuates liver fibrosis induced by CCl4 in mice. J Ethnopharmacol. 2014;153(3):659\u201366. doi:\n10.1016\/j.jep.2014.03.019\n\n.","journal-title":"J Ethnopharmacol"},{"issue":"4","key":"1857_CR13","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1177\/0960327108092294","volume":"27","author":"HM Chao","year":"2008","unstructured":"Chao HM, Chen YH, Liu JH, Lee SM, Lee FL, Chang Y, et al. Iron-generated hydroxyl radicals kill retinal cells in vivo: effect of ferulic acid. Hum Exp Toxicol. 2008a;27(4):327\u201339. doi:\n10.1177\/0960327108092294\n\n.","journal-title":"Hum Exp Toxicol"},{"issue":"5","key":"1857_CR14","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1177\/0960327108092294","volume":"24","author":"HM Chao","year":"2008","unstructured":"Chao HM, Lin DE, Chang Y, Hsu WM, Lee SM, Lee FL, et al. Ferulic acid, but not tetramethylpyrazine, significantly attenuates retinal ischemia\/reperfusion-induced alterations by acting as a hydroxyl radical scavenger. J Ocul Pharmacol Ther. 2008b;24(5):461\u201372. doi:\n10.1177\/0960327108092294\n\n.","journal-title":"J Ocul Pharmacol Ther"},{"key":"1857_CR15","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1186\/s13020-016-0096-7","volume":"11","author":"H Zhu","year":"2016","unstructured":"Zhu H, Wang Y, Liu Z, Wang J, Wan D, Feng S, et al. Antidiabetic and antioxidant effects of catalpol extracted from Rehmannia glutinosa (Di Huang) on rat diabetes induced by streptozotocin and high-fat, high-sugar feed. Chin Med. 2016;11:25\u201334. doi:\n10.1186\/s13020-016-0096-7\n\n.","journal-title":"Chin Med"},{"issue":"3","key":"1857_CR16","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1142\/S0192415X15500342","volume":"43","author":"Y Zhang","year":"2015","unstructured":"Zhang Y, Li H, Huang M, Huang M, Chu K, Xu W, et al. Paeoniflorin, a monoterpene glycoside, protects the brain from cerebral ischemic injury via inhibition of apoptosis. Am J Chin Med. 2015;43(3):543\u201357. doi:\n10.1142\/S0192415X15500342\n\n.","journal-title":"Am J Chin Med"},{"issue":"2","key":"1857_CR17","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/j.jep.2011.11.016","volume":"139","author":"L Liu","year":"2012","unstructured":"Liu L, Duan JA, Tang Y, Guo J, Yang N, Ma H, et al. Taoren\u2013Honghua herb pair and its main components promoting blood circulation through influencing on hemorheology, plasma coagulation and platelet aggregation. J Ethnopharmacol. 2012;139(2):381\u20137. doi:\n10.1016\/j.jep.2011.11.016\n\n.","journal-title":"J Ethnopharmacol"},{"issue":"2","key":"1857_CR18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1177\/1759091416642345","volume":"8","author":"X Wang","year":"2016","unstructured":"Wang X, Ma Z, Fu Z, Gao S, Yang L, Jin Y, et al. Hydroxysafflor yellow a protects neurons from excitotoxic death through inhibition of NMDARs. ASN Neuro. 2016;8(2):1\u201319. doi:\n10.1177\/1759091416642345\n\n.","journal-title":"ASN Neuro"},{"issue":"1","key":"1857_CR19","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1186\/s12974-016-0705-5","volume":"13","author":"X Xiong","year":"2016","unstructured":"Xiong X, Gu L, Wang Y, Luo Y, Zhang H, Lee J, et al. Glycyrrhizin protects against focal cerebral ischemia via inhibition of T cell activity and HMGB1-mediated mechanisms. J Neuroinflammation. 2016;13(1):241\u201352. doi:\n10.1186\/s12974-016-0705-5\n\n.","journal-title":"J Neuroinflammation"},{"issue":"7","key":"1857_CR20","doi-asserted-by":"publisher","first-page":"898","DOI":"10.3390\/molecules21070898","volume":"21","author":"CU Cheong","year":"2016","unstructured":"Cheong CU, Yeh CS, Hsieh YW, Lee YR, Lin MY, Chen CY, et al. Protective effects of Costunolide against hydrogen peroxide-induced injury in PC12 cells. Molecules. 2016 Jul 9;21(7):898\u2013907. doi:\n10.3390\/molecules21070898\n\n.","journal-title":"Molecules"},{"key":"1857_CR21","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.jep.2015.07.039","volume":"174","author":"WH Park","year":"2015","unstructured":"Park WH, Kang S, Piao Y, Pak CJ, Oh MS, Kim J, et al. Ethanol extract of Bupleurum Falcatum and saikosaponins inhibit neuroinflammation via inhibition of NF-\u03baB. J Ethnopharmacol. 2015 Nov 4;174:37\u201344. doi:\n10.1016\/j.jep.2015.07.039\n\n.","journal-title":"J Ethnopharmacol"},{"issue":"3","key":"1857_CR22","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1016\/j.carbpol.2008.08.003","volume":"75","author":"S Xue","year":"2009","unstructured":"Xue S, Chen X, Lu J, Jin L. Protective effect of sulfated Achyranthes bidentate polysaccharides on streptozotocin-induced oxidative stress in rats. Carbohydr Polym. 2009;75(3):415\u20139. doi:\n10.1016\/j.carbpol.2008.08.003\n\n.","journal-title":"Carbohydr Polym"},{"issue":"4","key":"1857_CR23","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1293\/tox.24.223","volume":"24","author":"JH Lim","year":"2011","unstructured":"Lim JH, Kim TW, Park SJ, Song IB, Kim MS, Kwon HJ, et al. Protective effects of Platycodon grandiflorum aqueous extract on thioacetamide-induced fulminant hepatic failure in mice. J Toxicol Pathol. 2011;24(4):223\u20138. doi:\n10.1293\/tox.24.223\n\n.","journal-title":"J Toxicol Pathol"},{"issue":"2","key":"1857_CR24","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1089\/jop.2011.0099","volume":"28","author":"YQ Chen","year":"2012","unstructured":"Chen YQ, Pan WH, Liu JH, Chen MM, Liu CM, Yeh MY, et al. The effects and underlying mechanisms of S-allyl l-cysteine treatment of the retina after ischemia\/reperfusion. J Ocul Pharmacol Ther. 2012;28(2):110\u20137. doi:\n10.1089\/jop.2011.0099\n\n.","journal-title":"J Ocul Pharmacol Ther"},{"issue":"6","key":"1857_CR25","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1089\/jop.2012.0179","volume":"29","author":"HM Chao","year":"2013","unstructured":"Chao HM, Chuang MJ, Liu JH, Liu XQ, Ho LK, Pan WH, et al. Baicalein protects against retinal ischemia by antioxidation, antiapoptosis, downregulation of HIF-1\u03b1, VEGF, and MMP-9 and upregulation of HO-1. J Ocul Pharmacol Ther. 2013;29(6):539\u201349. doi:\n10.1089\/jop.2012.0179\n\n.","journal-title":"J Ocul Pharmacol Ther"},{"issue":"1","key":"1857_CR26","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1136\/bjophthalmol-2013-304017","volume":"99","author":"RL Thomas","year":"2015","unstructured":"Thomas RL, Dunstan FD, Luzio SD, Chowdhury SR, North RV, Hale SL, et al. Prevalence of diabetic retinopathy within a national diabetic retinopathy screening service. Br J Ophthalmol. 2015;99(1):64\u20138. doi:\n10.1136\/bjophthalmol-2013-304017\n\n.","journal-title":"Br J Ophthalmol"},{"issue":"10","key":"1857_CR27","doi-asserted-by":"publisher","first-page":"2063","DOI":"10.1016\/j.ophtha.2015.06.018","volume":"122","author":"SJ Park","year":"2015","unstructured":"Park SJ, Kwon KE, Choi NK, Park KH, Woo SJ. Prevalence and incidence of exudative age-related macular degeneration in south Korea: a nationwide population-based study. Ophthalmology. 2015;122(10):2063\u201370. doi:\n10.1016\/j.ophtha.2015.06.018\n\n.","journal-title":"Ophthalmology"},{"key":"1857_CR28","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1097\/IAE.0b013e31814b1d6e","volume":"28","author":"E Opremcak","year":"2008","unstructured":"Opremcak E, Rehmar AJ, Ridenour CD, Borkowski LM, Kelley JK. Restoration of retinal blood flow via translumenal Nd:YAG embolysis\/embolectomy (TYL\/E) for central and branch retinal artery occlusion. Retina. 2008;28:226\u201335. doi:\n10.1097\/IAE.0b013e31814b1d6e\n\n.","journal-title":"Retina"},{"issue":"42","key":"1857_CR29","doi-asserted-by":"publisher","first-page":"28956","DOI":"10.1074\/jbc.M114.573725","volume":"289","author":"G Nishibuchi","year":"2014","unstructured":"Nishibuchi G, Shibata Y, Hayakawa T, Hayakawa N, Ohtani Y, Sinmyozu K, et al. Physical and functional interactions between the histone H3K4 demethylase KDM5A and the nucleosome remodeling and deacetylase (NuRD) complex. J Biol Chem. 2014 Oct 17;289(42):28956\u201370. doi:\n10.1074\/jbc.M114.573725\n\n.","journal-title":"J Biol Chem"},{"issue":"6","key":"1857_CR30","doi-asserted-by":"publisher","first-page":"2631","DOI":"10.1074\/jbc.M115.698449","volume":"291","author":"JR Horton","year":"2016","unstructured":"Horton JR, Engstrom A, Zoeller EL, Liu X, Shanks JR, Zhang X, et al. Characterization of a linked Jumonji domain of the KDM5\/JARID1 family of histone H3 lysine 4 demethylases. J Biol Chem. 2016 Feb 5;291(6):2631\u201346. doi:\n10.1074\/jbc.M115.698449\n\n.","journal-title":"J Biol Chem"},{"issue":"2","key":"1857_CR31","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/0009-9120(90)80029-I","volume":"23","author":"S Miwa","year":"1990","unstructured":"Miwa S, Fujii H. Pyruvate kinase deficiency. Clin Biochem. 1990;23(2):155\u20137. PMID: 2197027","journal-title":"Clin Biochem"},{"key":"1857_CR32","doi-asserted-by":"crossref","unstructured":"Imamura, K., Tanaka, T. Pyruvate kinase isozymes from rat. In: Willis, AW, editor. Methods in Enzymology. Academic Press; 1982. p. 150-165.","DOI":"10.1016\/S0076-6879(82)90121-5"},{"issue":"1","key":"1857_CR33","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.molcel.2014.10.027","volume":"57","author":"SY Lunt","year":"2015","unstructured":"Lunt SY, Muralidhar V, Hosios AM, Israelsen WJ, Gui DY, Newhouse L, et al. Pyruvate kinase isoform expression alters nucleotide synthesis to impact cell proliferation. Mol Cell. 2015;57(1):95\u2013107. doi:\n10.1016\/j.molcel.2014.10.027\n\n.","journal-title":"Mol Cell"},{"key":"1857_CR34","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/s12943-015-0490-2","volume":"15","author":"N Azoitei","year":"2016","unstructured":"Azoitei N, Becher A, Steinestel K, Rouhi A, Diepold K, Genze F, et al. PKM2 promotes tumor angiogenesis by regulating HIF-1\u03b1 through NF-\u03baB activation. Mol Cancer. 2016;15:3\u201317. doi:\n10.1186\/s12943-015-0490-2\n\n.","journal-title":"Mol Cancer"},{"issue":"8","key":"1857_CR35","doi-asserted-by":"publisher","first-page":"e106032","DOI":"10.1371\/journal.pone.0106032","volume":"9","author":"L Qi","year":"2014","unstructured":"Qi L. Zhu, Li SH, Si LB, Hu LK, Tian H. Retinoblastoma binding protein 2 (RBP2) promotes HIF-1\u03b1-VEGF-induced angiogenesis of non-small cell lung cancer via the Akt pathway. PLoS One. 2014;9(8):e106032\u201343. doi:\n10.1371\/journal.pone.0106032\n\n.","journal-title":"PLoS One"},{"issue":"4","key":"1857_CR36","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1111\/ceo.12462","volume":"43","author":"SK Ng","year":"2015","unstructured":"Ng SK, Wood JP, Chidlow G, Han G, Kittipassorn T, Peet DJ, et al. Cancer-like metabolism of the mammalian retina. Clin Exp Ophthalmol. 2015;43(4):367\u201376. doi:\n10.1111\/ceo.12462\n\n.","journal-title":"Clin Exp Ophthalmol"},{"key":"1857_CR37","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/j.jep.2016.07.023","volume":"192","author":"SH Kim","year":"2016","unstructured":"Kim SH, Park HS, Hong MJ, Yoo JY, Lee H, Lee JA, et al. Tongqiaohuoxue decoction ameliorates obesity-induced inflammation and the prothrombotic state by regulating adiponectin and plasminogen activator inhibitor-1. J Ethnopharmacol. 2016 Nov 4;192:201\u20139. doi:\n10.1016\/j.jep.2016.07.023\n\n.","journal-title":"J Ethnopharmacol"},{"issue":"6","key":"1857_CR38","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/0042-6989(68)90041-2","volume":"8","author":"KT Brown","year":"1968","unstructured":"Brown KT. The electroretinogram: its components and their origins. Vis Res. 1968;8(6):633\u201377. PMID: \n4978009","journal-title":"Vis Res"},{"issue":"1","key":"1857_CR39","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1085\/jgp.93.1.101","volume":"93","author":"RA Stockton","year":"1989","unstructured":"Stockton RA, Slaughter MM. B-wave of the electroretinogram. A reflection of ON bipolar cell activity. J Gen Physiol. 1989;93(1):101\u201322. PMCID: \nPMC2216200","journal-title":"J Gen Physiol"},{"issue":"5","key":"1857_CR40","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1016\/j.cell.2011.03.054","volume":"145","author":"W Luo","year":"2011","unstructured":"Luo W, Hu H, Chang R, Zhong J, Knabel M, O'Meally R, et al. Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1. Cell. 2011;145(5):732\u201344. doi:\n10.1016\/j.cell.2011.03.054\n\n.","journal-title":"Cell"},{"key":"1857_CR41","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/S0002-9394(00)00384-6","volume":"129","author":"SS Hayreh","year":"2000","unstructured":"Hayreh SS, Jonas JB. Optic disk and retinal nerve fiber layer damage after transient central retinal artery occlusion: an experimental study in rhesus monkeys. Am J Ophthalmol. 2000;129:786\u201395. PMID: \n10926989","journal-title":"Am J Ophthalmol"},{"key":"1857_CR42","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/S0014-4835(03)00214-8","volume":"78","author":"SS Hayreh","year":"2004","unstructured":"Hayreh SS, Zimmerman MB, Kimura A, Sanon A. Central retinal artery occlusion. Retinal survival time. Exp. Eye Res. 2004;78:723\u201336. PMID: \n15106952","journal-title":"Eye Res"},{"key":"1857_CR43","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1016\/j.ajo.2008.05.009","volume":"146","author":"JO Mason III","year":"2008","unstructured":"Mason JO III, Shah AA, Vail RS, Nixon PA, Ready EL, Kimble JA. Branch retinal artery occlusion: visual prognosis. Am J Ophthalmol. 2008;146:455\u20137. doi:\n10.1016\/j.ajo.2008.05.009\n\n.","journal-title":"Am J Ophthalmol"},{"issue":"3","key":"1857_CR44","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1097\/ICB.0b013e3182852370","volume":"7","author":"TK Hsu","year":"2013","unstructured":"Hsu TK, Chen SJ, Lei J, Wu Z, Lin CC, Chen MM, et al. Embolus-induced branch retinal artery occlusion with a presenting best-corrected visual acuity of <6\/12 and visual field defect: yag embolectomy safely restores arteriolar perfusion and\/or visual function. Retin Cases Brief Rep. 2013;7(3):210\u20136. doi:\n10.1097\/ICB.0b013e3182852370\n\n.","journal-title":"Retin Cases Brief Rep"},{"issue":"26","key":"1857_CR45","doi-asserted-by":"crossref","first-page":"3251","DOI":"10.2174\/09298673113209990024","volume":"20","author":"C Hernandez","year":"2013","unstructured":"Hernandez C, Simo R. Somatostatin replacement: a new strategy for treating diabetic retinopathy. Curr Med Chem. 2013;20(26):3251\u20137. PMID: \n23745546","journal-title":"Curr Med Chem"},{"key":"1857_CR46","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1055\/s-0030-1255355","volume":"30","author":"O Rosmorduc","year":"2010","unstructured":"Rosmorduc O, Housset C. Hypoxia: a link between fibrogenesis, angiogenesis, and carcinogenesis in liver disease. Semin Liver Dis. 2010;30:258\u201370. doi:\n10.1055\/s-0030-1255355\n\n.","journal-title":"Semin Liver Dis"},{"key":"1857_CR47","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1002\/hep.25497","volume":"55","author":"B Nath","year":"2012","unstructured":"Nath B, Szabo G. Hypoxia and hypoxia inducible factors: diverse roles in liver diseases. Hepatology. 2012;55:622\u201333. doi:\n10.1002\/hep.25497\n\n.","journal-title":"Hepatology"}],"container-title":["BMC Complementary and Alternative Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12906-017-1857-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,7,14]],"date-time":"2017-07-14T11:09:10Z","timestamp":1500030550000},"score":1,"resource":{"primary":{"URL":"http:\/\/bmccomplementalternmed.biomedcentral.com\/articles\/10.1186\/s12906-017-1857-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,14]]},"references-count":47,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["1857"],"URL":"https:\/\/doi.org\/10.1186\/s12906-017-1857-2","relation":{},"ISSN":["1472-6882"],"issn-type":[{"value":"1472-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7,14]]},"article-number":"365"}}