{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,26]],"date-time":"2025-08-26T06:37:48Z","timestamp":1756190268089},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T00:00:00Z","timestamp":1720051200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T00:00:00Z","timestamp":1720051200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Complement Med Ther"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background and objectives<\/jats:title>\n                <jats:p>Considering the significant prevalence of ileus after abdominal surgery and the beneficial effects of <jats:italic>Cuminum cyminum<\/jats:italic> in digestive problems, this study aimed to examine whether <jats:italic>Cuminum cyminum<\/jats:italic> has any effect on the return of bowel motility after abdominal surgery.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Materials and methods<\/jats:title>\n                <jats:p>In this triple-blind clinical trial study, 74 patients undergoing abdominal surgery were assigned to the intervention and control groups using minimization methods. The patients in the intervention group consumed 250\u00a0mg capsules containing <jats:italic>Cuminum cyminum<\/jats:italic> extract 4\u00a0h after the surgery and another dose of the drug 1\u00a0h afterward. The patients in the control group consumed a 250\u00a0mg capsule containing starch as a placebo at hours similar to those in the intervention group. The instruments used to collect the data were a demographic questionnaire and a researcher-made checklist to assess bowel habits. The data were analyzed using SPSS-22 software.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The average time of gas passing in the intervention and control groups was 9.03\u2009\u00b1\u20093.41 and 11.72\u2009\u00b1\u20094.21\u00a0h, respectively. The defecation times in the intervention and control groups were 16.97\u2009\u00b1\u20095.02 and 26\u2009\u00b1\u20099.87\u00a0h, showing a significant difference between the two groups as indicated by the independent samples T-test (<jats:italic>P<\/jats:italic>\u2009&gt;\u20090.001). Furthermore, abdominal pain, abdominal bloating, nausea, and vomiting were significantly less frequent in the intervention group compared to the control group as confirmed by Fisher\u2019s exact test (<jats:italic>P<\/jats:italic>\u2009&gt;\u20090.001).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>According to the results, the consumption of <jats:italic>Cuminum cyminum<\/jats:italic> after abdominal surgery helps to reduce the time of gas passing, defecation, and the return of bowel motility. However, additional studies need to address the effectiveness of <jats:italic>Cuminum cyminum<\/jats:italic> by changing the time and duration of its use.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12906-024-04530-1","type":"journal-article","created":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T13:02:17Z","timestamp":1720098137000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The effect of Cuminum cyminum on the return of bowel motility after abdominal surgery: a triple-blind randomized clinical trial"],"prefix":"10.1186","volume":"24","author":[{"given":"Esmaeili Abdar","family":"Amin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elahabadi","family":"Ismail","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raeiszadeh","family":"Mahboobeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sadeghi","family":"Tabandeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,7,4]]},"reference":[{"issue":"7","key":"4530_CR1","first-page":"11","volume":"3","author":"C Bosc","year":"2021","unstructured":"Bosc C, Hebbard DP. 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The study objectives were explained to the patients, with their names and information kept confidential. In addition, the principles of confidentiality were met in publishing information, and the participants were assured to be free to leave the study at any time they desired.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not Applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"254"}}