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Important protocol modifications of the protocol will be reported to the committee, trial registries, and the journals. This study protocol follows the Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) checklist and the TIDieR checklist. It is per-registered at the Trial Register under registration number ChiCTR2100044553 (). Informed consent will be obtained from the adolescent participants, their parents and legally authorized representatives in this study. Participants in the project can get feedback reports of all test results and they were compensated for their participation. De-identified data will be used for statistical analysis and the results of this trial will be disseminated through publications in peer-reviewed journals and academic conferences.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"403"}}