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All the participants will be given and signed a written consent form before being recruited into our study. In case of essential protocol modifications, a new version of the protocol with appropriate amendments will be submitted to the ethics committee for approval. Further studies may begin when the new protocol or changes to the existing protocol have been approved by the ethics committee. In addition, if administrative changes to the protocol are minor corrections and\/or clarifications that have no effect on conducting the study, then these administrative changes will be agreed upon by the ethics committee, and will be documented in a memorandum. Substantive protocol amendments will also be transparently described in trial reports.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Participants signed informed consent regarding publishing their photographs.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"357"}}