{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:54:30Z","timestamp":1761746070585,"version":"3.40.3"},"reference-count":106,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T00:00:00Z","timestamp":1743033600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T00:00:00Z","timestamp":1743033600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"Faculty Research Funding Program, 2022, Enterprise Incubator Foundation, Armenia"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Complement Med Ther"],"DOI":"10.1186\/s12906-024-04715-8","type":"journal-article","created":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T13:03:22Z","timestamp":1743080602000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Teucrium Polium ameliorates amyloid \u03b2-induced brain network disorders in rats: electrophysiological and behavioral studies"],"prefix":"10.1186","volume":"25","author":[{"given":"Karen","family":"Simonyan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lilit","family":"Darbinyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lilia","family":"Hambardzumyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larisa","family":"Manukyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vergine","family":"Chavushyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,3,27]]},"reference":[{"doi-asserted-by":"crossref","unstructured":"Wilson DM 3rd, Cookson MR, Van Den Bosch L, Zetterberg H, Holtzman DM, Dewachter I. Hallmarks of neurodegenerative diseases. Cell. 2023 Feb 16;186(4):693\u2013714.","key":"4715_CR1","DOI":"10.1016\/j.cell.2022.12.032"},{"key":"4715_CR2","doi-asserted-by":"publisher","first-page":"782768","DOI":"10.3389\/fncel.2021.782768","volume":"15","author":"HB Taylor","year":"2021","unstructured":"Taylor HB, Jeans AF. Friend or foe? The varied faces of homeostatic synaptic plasticity in neurodegenerative disease. Front Cell Neurosci. 2021;15:782768.","journal-title":"Front Cell Neurosci"},{"key":"4715_CR3","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1016\/j.neuron.2013.09.044","volume":"80","author":"GW Davis","year":"2013","unstructured":"Davis GW. Homeostatic signaling and the stabilization of neural function. Neuron. 2013;80:718\u201328.","journal-title":"Neuron"},{"issue":"7010","key":"4715_CR4","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1038\/nature03010","volume":"431","author":"LF Abbott","year":"2004","unstructured":"Abbott LF, Regehr WG. Synaptic computation. Nature. 2004;431(7010):796\u2013803.","journal-title":"Nature"},{"key":"4715_CR5","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1186\/s13041-020-00617-1","volume":"13","author":"R Tong","year":"2020","unstructured":"Tong R, Emptage NJ, Padamsey Z. A two-compartment model of synaptic computation and plasticity. Mol Brain. 2020;13:79.","journal-title":"Mol Brain"},{"key":"4715_CR6","doi-asserted-by":"publisher","first-page":"196","DOI":"10.3389\/fncel.2020.00196","volume":"14","author":"P Goel","year":"2020","unstructured":"Goel P, Nishimura S, Chetlapalli K, Li X, Chen C, Dickman D. Distinct target-specific mechanisms homeostatically stabilize transmission at pre- and post-synaptic compartments. Front Cell Neurosci. 2020;14:196.","journal-title":"Front Cell Neurosci"},{"doi-asserted-by":"crossref","unstructured":"Kavalali ET et al. Targeting homeostatic synaptic plasticity for treatment of Mood disorders. Neuron 2020 Jun 3;106(5):715\u201326.","key":"4715_CR7","DOI":"10.1016\/j.neuron.2020.05.015"},{"issue":"2","key":"4715_CR8","first-page":"365","volume":"93","author":"PA Maher","year":"2020","unstructured":"Maher PA. Using plants as a source of potential therapeutics for the treatment of Alzheimer\u2019s Disease. Yale J Biol Med. 2020;93(2):365\u201373.","journal-title":"Yale J Biol Med"},{"issue":"1","key":"4715_CR9","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1186\/s12906-017-2040-5","volume":"17","author":"J Shi","year":"2017","unstructured":"Shi J, Ni J, Lu T, Zhang X, Wei M, Li T, Liu W, Wang Y, Shi Y, Tian J. Adding Chinese herbal medicine to conventional therapy brings cognitive benefits to patients with Alzheimer\u2019s disease: a retrospective analysis. BMC Complement Altern Med. 2017;17(1):533.","journal-title":"BMC Complement Altern Med"},{"issue":"1","key":"4715_CR10","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1039\/C0NP00027B","volume":"28","author":"P Williams","year":"2011","unstructured":"Williams P, Sorribas A, Howes MJ. Natural products as a source of Alzheimer\u2019s drug leads. Nat Prod Rep. 2011;28(1):48\u201377.","journal-title":"Nat Prod Rep"},{"issue":"10","key":"4715_CR11","doi-asserted-by":"publisher","first-page":"3222","DOI":"10.3390\/molecules27103222","volume":"27","author":"T Tuzimski","year":"2022","unstructured":"Tuzimski T, Petruczynik A. Determination of Anti-alzheimer\u2019s Disease activity of selected plant ingredients. Molecules. 2022;27(10):3222.","journal-title":"Molecules"},{"issue":"10","key":"4715_CR12","doi-asserted-by":"publisher","first-page":"1579","DOI":"10.3390\/life12101579","volume":"12","author":"N Benchikha","year":"2022","unstructured":"Benchikha N, Messaoudi M, Larkem I, Ouakouak H, Rebiai A, Boubekeur S, Ferhat MA, Benarfa A, Begaa S, Benmohamed M, et al. Evaluation of possible Antioxidant, Anti-Hyperglycaemic, Anti-alzheimer and Anti-inflammatory effects of Teucrium Polium Aerial Parts (Lamiaceae). Life. 2022;12(10):1579.","journal-title":"Life"},{"key":"4715_CR13","first-page":"87","volume":"3","author":"N Suganthy","year":"2009","unstructured":"Suganthy N, Pandian SK, Devi KP. Cholinesterase inhibitors from plants: possible treatment strategy for neurological disorders\u2013a review. Int J Biomed Pharm Sci. 2009;3:87\u2013103.","journal-title":"Int J Biomed Pharm Sci"},{"key":"4715_CR14","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/S0166-4328(00)00215-1","volume":"113","author":"A Wevers","year":"2000","unstructured":"Wevers A, Burghaus L, Moser N, et al. Expression of nicotinic acetylcholine receptors in Alzheimer\u2019s disease: Postmortem investigations and experimental approaches. Behav Brain Res. 2000;113:207\u201315.","journal-title":"Behav Brain Res"},{"key":"4715_CR15","doi-asserted-by":"publisher","first-page":"1625","DOI":"10.1007\/s00702-006-0579-2","volume":"113","author":"R Schliebs","year":"2006","unstructured":"Schliebs R, Arendt T. The significance of the cholinergic system in the brain during aging and in Alzheimer\u2019s disease. J Neural Transm. 2006;113:1625\u201344.","journal-title":"J Neural Transm"},{"key":"4715_CR16","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1097\/NEN.0b013e31816a1df3","volume":"67","author":"C Geula","year":"2008","unstructured":"Geula C, Nagykery N, Nicholas A, Wu CK. Cholinergic neuronal and axonal abnormalities are present early in aging and in Alzheimer disease. J Neuropathol Exp Neurol. 2008;67:309\u201318.","journal-title":"J Neuropathol Exp Neurol"},{"issue":"2","key":"4715_CR17","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1136\/jnnp.66.2.137","volume":"66","author":"PT Francis","year":"1999","unstructured":"Francis PT, Palmer AM, Snape M, Wilcock GK. The cholinergic hypothesis of Alzheimer\u2019s disease: a review of progress. J NeurolNeurosurg Psychiatry. 1999;66(2):137\u201347.","journal-title":"J NeurolNeurosurg Psychiatry"},{"key":"4715_CR18","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1007\/s00213-006-0447-7","volume":"188","author":"A Kadir","year":"2006","unstructured":"Kadir A, Almkvist O, Wall A, Langstrom B, Nordberg A. PET imaging of cortical 11\u00a0C-nicotine binding correlates with the cognitive function of attention in Alzheimer\u2019s disease. Psychopharmacology. 2006;188:509\u201320.","journal-title":"Psychopharmacology"},{"key":"4715_CR19","doi-asserted-by":"publisher","first-page":"27","DOI":"10.2174\/156720510790274464","volume":"7","author":"RH Parri","year":"2010","unstructured":"Parri RH, Dineley TK. Nicotinic acetylcholine receptor interaction with beta-amyloid: molecular, cellular, and physiological consequences. Curr Alzheimer Res. 2010;7:27\u201339.","journal-title":"Curr Alzheimer Res"},{"issue":"4","key":"4715_CR20","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/S0011-393X(03)00059-6","volume":"64","author":"GT Grossberg","year":"2003","unstructured":"Grossberg GT. Cholinesterase inhibitors for the treatment of Alzheimer\u2019s disease:: getting on and staying on. Curr Ther Res Clin Exp. 2003;64(4):216\u201335.","journal-title":"Curr Ther Res Clin Exp"},{"key":"4715_CR21","doi-asserted-by":"publisher","first-page":"108352","DOI":"10.1016\/j.neuropharm.2020.108352","volume":"190","author":"G Marucci","year":"2021","unstructured":"Marucci G, Buccioni M, Ben DD, Lambertucci C, Volpini R, Amenta F. Efficacy of acetylcholinesterase inhibitors in Alzheimer\u2019s disease. Neuropharmacology. 2021;190:108352.","journal-title":"Neuropharmacology"},{"issue":"2","key":"4715_CR22","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1097\/00002093-200304000-00011","volume":"17","author":"S Darvesh","year":"2003","unstructured":"Darvesh S, Walsh R, Kumar R, et al. Inhibition of human cholinesterases by drugs used to treat Alzheimer disease. Alzheimer Dis AssocDisord. 2003;17(2):117\u201326.","journal-title":"Alzheimer Dis AssocDisord"},{"key":"4715_CR23","first-page":"273","volume":"4","author":"EK Perry","year":"1978","unstructured":"Perry EK, Perry RH, Blessed G, Tomlinson BE. Changes in brain cholinesterases in senile dementia of Alzheimer type. NeuropatholApplNeurobiol. 1978;4:273\u20137.","journal-title":"NeuropatholApplNeurobiol"},{"key":"4715_CR24","first-page":"31","volume-title":"Butyrylcholiesterase: its function and inhibitors","author":"MM Mesulam","year":"2003","unstructured":"Mesulam MM. Butyrylcholinesterase in the normal and Alzheimer brain. In: Giacobini E, editor. Butyrylcholiesterase: its function and inhibitors. London: Martin Dunitz; 2003. pp. 31\u20134."},{"issue":"11","key":"4715_CR25","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1007\/s40266-017-0499-x","volume":"34","author":"R Khoury","year":"2017","unstructured":"Khoury R, Patel K, Gold J, Hinds S, Grossberg GT. Recent progress in the Pharmacotherapy of Alzheimer\u2019s Disease. Drugs Aging. 2017;34(11):811\u201320.","journal-title":"Drugs Aging"},{"key":"4715_CR26","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.1002\/(SICI)1099-1166(199612)11:12<1063::AID-GPS532>3.0.CO;2-1","volume":"11","author":"N Perry","year":"1996","unstructured":"Perry N, Court G, Bidet N, et al. Cholinergic activities of European herbs and potential for dementia therapy. J Geriatr Psychiatry. 1996;11:1063\u201369.","journal-title":"J Geriatr Psychiatry"},{"key":"4715_CR27","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/ptr.1280","volume":"17","author":"MJR Howes","year":"2003","unstructured":"Howes MJR, Perry NSL, Houghton PJ. Plants with traditional uses and activities relevant to the management of Alzheimer\u2019s disease and other cognitive disorders. Phytother Res. 2003;17:1\u201318.","journal-title":"Phytother Res"},{"key":"4715_CR28","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/j.jep.2008.12.026","volume":"122","author":"I Orhan","year":"2009","unstructured":"Orhan I, Aslan M. Appraisal of scopolamine-induced antiamnesic effect in mice and in vitro antiacetylcholinesterase and antioxidant activities of some traditionally used Lamiaceae plants. J Ethnopharmacol. 2009;122:327\u201332.","journal-title":"J Ethnopharmacol"},{"key":"4715_CR29","doi-asserted-by":"publisher","first-page":"315","DOI":"10.3923\/ijp.2010.315.325","volume":"6","author":"S Hasani-Ranjbar","year":"2010","unstructured":"Hasani-Ranjbar S, Nayebi N, Larijani B, et al. A systematic review of the efficacy and safety of Teucrium species; from anti-oxidant to antidiabetic effects. Int J Pharmacol. 2010;6:315\u201325.","journal-title":"Int J Pharmacol"},{"issue":"11","key":"4715_CR30","doi-asserted-by":"publisher","first-page":"1581","DOI":"10.1002\/ptr.4617","volume":"26","author":"S Bahramikia","year":"2012","unstructured":"Bahramikia S, Yazdanparast R. Phytochemistry and Medicinal properties of Teucrium Polium L. (Lamiaceae). Phytother Res. 2012;26(11):1581\u201393.","journal-title":"Phytother Res"},{"key":"4715_CR31","doi-asserted-by":"publisher","first-page":"1","DOI":"10.14235\/bs.2014.233","volume":"1","author":"G Topcu","year":"2014","unstructured":"Topcu G, Kusman T. Lamiaceae Family Plants as a potential anticholinesterase source in the treatment of Alzheimer\u2019s Disease. Bezmialem Sci. 2014;1:1\u201325.","journal-title":"Bezmialem Sci"},{"key":"4715_CR32","doi-asserted-by":"publisher","first-page":"1247","DOI":"10.1016\/j.foodchem.2006.10.030","volume":"103","author":"I Orhan","year":"2007","unstructured":"Orhan I, Kartal M, Naz Q, Ejaz A, Yilmaz G, Kan Y, KonuklugilB, Choudhary MI. Antioxidant and anticholinesterase evaluation of selected Turkish Salvia species. Food Chem. 2007;103:1247\u201312254.","journal-title":"Food Chem"},{"issue":"49","key":"4715_CR33","first-page":"8257","volume":"9","author":"EA Adewusi","year":"2010","unstructured":"Adewusi EA, Moodley N, Steenkamp V. Medicinal plants with cholinesterase inhibitory activity: a review. Afr J Biotechnol. 2010;9(49):8257\u201376.","journal-title":"Afr J Biotechnol"},{"key":"4715_CR34","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1007\/BF00630353","volume":"27","author":"GB Oganesyan","year":"1991","unstructured":"Oganesyan GB, Galstyan AM, Mnatsakanyan VA, Shashkov AS, Agababyan PV. Phenylpropanoid glycosides of Teucrium Polium. Chem Nat Compd. 1991;27:556\u20139.","journal-title":"Chem Nat Compd"},{"key":"4715_CR35","first-page":"223","volume":"2","author":"HM Galstyan","year":"1992","unstructured":"Galstyan HM, Shashkov AS, et al. Structure of two new deterpenoids of Teucrium polium L. Chem Nat Compd. 1992;2:223\u201330.","journal-title":"Chem Nat Compd"},{"issue":"2","key":"4715_CR36","first-page":"53","volume":"8","author":"HM Galstyan","year":"2014","unstructured":"Galstyan HM. Standardization of Teucrium Polium L. by natural phytoestrogens- phenylpropanoid glycosids and flavonoids. NAMJ. 2014;8(2):53\u20138.","journal-title":"NAMJ"},{"issue":"24","key":"4715_CR37","doi-asserted-by":"publisher","first-page":"7646","DOI":"10.3390\/molecules26247646","volume":"26","author":"Y Amen","year":"2021","unstructured":"Amen Y, Elsbaey M, Othman A, Sallam M, Shimizu K. Naturally occurring Chromone glycosides: sources, bioactivities, and Spectroscopic features. Molecules. 2021;26(24):7646.","journal-title":"Molecules"},{"issue":"1","key":"4715_CR38","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1186\/s12906-016-1407-3","volume":"16","author":"KV Simonyan","year":"2016","unstructured":"Simonyan KV, Chavushyan V. A.Protective effects of hydroponic Teucrium polium on hippocampal neurodegeneration in ovariectomized rats. BMC Complement Altern Med. 2016;16(1):415.","journal-title":"BMC Complement Altern Med"},{"unstructured":"Tadevosyan NE, Tumanyan GHM, Forgan AA. B. B. Dynamics of cognitive processes in middle age women under administration of fraction of hydroponic Teucrium poliumLamiaceae. Russian Journal of Physiology. 2017, V. 103. N 9. P. 1069\u20131076.","key":"4715_CR39"},{"issue":"4\u20135","key":"4715_CR40","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.brainresbull.2009.06.006","volume":"80","author":"A Savioz","year":"2009","unstructured":"Savioz A, Leuba G, Vallet PG, Walzer C. Contribution of neural networks to Alzheimer disease\u2019s progression. Brain Res Bull. 2009;80(4\u20135):309\u201314.","journal-title":"Brain Res Bull"},{"key":"4715_CR41","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.molmed.2007.12.006","volume":"14","author":"DH Small","year":"2008","unstructured":"Small DH. Network dysfunction in Alzheimer\u2019s disease: does synaptic scaling drive disease progression? Trends Mol Med. 2008;14:103\u20138.","journal-title":"Trends Mol Med"},{"issue":"10","key":"4715_CR42","doi-asserted-by":"publisher","first-page":"297","DOI":"10.3390\/ph13100297","volume":"13","author":"V Chavushyan","year":"2020","unstructured":"Chavushyan V, Soghomonyan A, Karapetyan G, Simonyan K, Yenkoyan K. Disruption of Cholinergic circuits as an area for targeted drug treatment of Alzheimer\u2019s Disease: in vivo Assessment of short-term plasticity in rat brain. Pharmaceuticals (Basel). 2020;13(10):297.","journal-title":"Pharmaceuticals (Basel)"},{"issue":"2","key":"4715_CR43","doi-asserted-by":"publisher","first-page":"94","DOI":"10.4103\/0976-500X.72351","volume":"1","author":"C Kilkenny","year":"2010","unstructured":"Kilkenny C, Browne WJ, Cuthill IC, Emerson M, Altman DG. Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research. J Pharmacol Pharmacother. 2010;1(2):94\u20139.","journal-title":"J Pharmacol Pharmacother"},{"doi-asserted-by":"crossref","unstructured":"Chavushyan V, Simonyan K, Galstyan H. Toxicity studies of Teucrium poliumlamiaceae growing in nature and in culture. The Second International symposium Biopharma 2010: from science to industry May 17\u201320 Armenia. Yerevan: 2010. p. 11, 45.","key":"4715_CR44","DOI":"10.1176\/pn.45.6.psychnews_45_6_037"},{"issue":"3","key":"4715_CR45","first-page":"104","volume":"4","author":"HM Galstyan","year":"2010","unstructured":"Galstyan HM, Revazova LV, Topchyan HV. Digital indices and microscopic analyses of wild growing and overgrowing of Teucrium Polium L. in hidroponic conditions. New Armen Med J. 2010;4(3):104.","journal-title":"New Armen Med J"},{"key":"4715_CR46","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1016\/S0306-4522(97)00405-3","volume":"83","author":"T Maurice","year":"1998","unstructured":"Maurice T, Privat A. Sigma1 (sigma 1) receptor agonists and neurosteroids attenuate beta25\u201335-amyloid peptide-induced amnesia in mice through a common mechanism. Neuroscience. 1998;83:413\u201328.","journal-title":"Neuroscience"},{"unstructured":"Paxinos G, Watson C. The Rat Brain in Stereotaxic Coordinates. \/\/ 5th Edition. New York: Academic Press. 2005; P.367.","key":"4715_CR47"},{"issue":"4","key":"4715_CR48","first-page":"888","volume":"72","author":"K Simonyan","year":"2022","unstructured":"Simonyan K, Avetisyan L, Isoyan A, Chavushyan V. Plasticity in Motoneurons Following Spinal Cord Injury in Fructose-induced Diabetic rats. J MolNeurosci. 2022;72(4):888\u201399.","journal-title":"J MolNeurosci"},{"key":"4715_CR49","doi-asserted-by":"publisher","first-page":"102458","DOI":"10.1016\/j.jtherbio.2019.102458","volume":"87","author":"H Nakagawa","year":"2020","unstructured":"Nakagawa H, Matsunaga D, Ishiwata T. Effect of heat acclimation on anxiety-like behavior of rats in an open field. J Therm Biol. 2020;87:102458.","journal-title":"J Therm Biol"},{"doi-asserted-by":"crossref","unstructured":"Ballinger EC, Ananth M, Talmage DA, Role LW. Basal Forebrain Cholinergic Circuits and Signaling in Cognition and Cognitive Decline. Neuron. 2016;91(6):1199\u2013218.","key":"4715_CR50","DOI":"10.1016\/j.neuron.2016.09.006"},{"doi-asserted-by":"crossref","unstructured":"Lee JE, Jeong DU, Lee J, Chang WS, Chang JW. The effect of nucleus basalis magnocellularis deep brain stimulation on memory function in a rat model of dementia. BMC Neurol. 2016;16:6.","key":"4715_CR51","DOI":"10.1186\/s12883-016-0529-z"},{"issue":"1\u20133","key":"4715_CR52","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/S0014-2999(03)01272-X","volume":"463","author":"L Prut","year":"2003","unstructured":"Prut L, Belzung C. The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review. Eur J Pharmacol. 2003;463(1\u20133):3\u201333.","journal-title":"Eur J Pharmacol"},{"doi-asserted-by":"crossref","unstructured":"Mesulam MM, Hersh LB, Mash DC, Geula C. Differential cholinergic innervation within functional subdivisions of the human cerebral cortex: a choline acetyltransferase study. J Comp Neurol. 1992;318(3):316\u201328.","key":"4715_CR53","DOI":"10.1002\/cne.903180308"},{"doi-asserted-by":"crossref","unstructured":"Botly LCP, Baxter MG, De Rosa E. Basal Forebrain and Memory., in Encyclopedia of Neuroscience, 2009.","key":"4715_CR54","DOI":"10.1016\/B978-008045046-9.00748-8"},{"doi-asserted-by":"crossref","unstructured":"Mesulam M. The cholinergic lesion of Alzheimer\u2019s disease: pivotal factor or side show? Learn Mem. 2004 Jan-Feb;11(1):43\u2009\u2013\u20099.","key":"4715_CR55","DOI":"10.1101\/lm.69204"},{"issue":"6","key":"4715_CR56","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1016\/0361-9230(82)90102-2","volume":"8","author":"NJ Woolf","year":"1982","unstructured":"Woolf NJ. Butcher LL Cholinergic projections to the basolateral amygdala: a combined Evans Blue and acetylcholinesterase analysis. Brain Res Bull. 1982;8(6):751\u201363.","journal-title":"Brain Res Bull"},{"key":"4715_CR57","doi-asserted-by":"publisher","first-page":"1155","DOI":"10.1016\/j.cell.2015.07.057","volume":"162","author":"B Hangya","year":"2015","unstructured":"Hangya B, Ranade SP, Lorenc M, Kepecs A. Central cholinergic neurons are rapidly recruited by reinforcement feedback. Cell. 2015;162:1155\u201368.","journal-title":"Cell"},{"issue":"12","key":"4715_CR58","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1101\/lm.675907","volume":"14","author":"E Baldi","year":"2007","unstructured":"Baldi E, Mariottini C, Bucherelli C. The role of the nucleus basalis magnocellularis in fear conditioning consolidation in the rat. Learn Mem. 2007;14(12):855\u201360.","journal-title":"Learn Mem"},{"issue":"1","key":"4715_CR59","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1007\/s00221-001-0917-4","volume":"142","author":"A Vale-Mart\u00ednez","year":"2002","unstructured":"Vale-Mart\u00ednez A, Guillazo-Blanch G, Mart\u00ed-Nicolovius M, Nadal R, Ar\u00e9valo-Garc\u00eda R, Morgado-Bernal I. Electrolytic and ibotenic acid lesions of the nucleus basalis magnocellularis interrupt long-term retention, but not acquisition of two-way active avoidance, in rats. Exp Brain Res. 2002;142(1):52\u201366.","journal-title":"Exp Brain Res"},{"key":"4715_CR60","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1016\/j.brainres.2016.11.013","volume":"1655","author":"N Hosseini","year":"2017","unstructured":"Hosseini N, Alaei H, Reisi P, Radahmadi M. The effects of NBM- lesion on synaptic plasticity in rats. Brain Res. 2017;1655:122\u20137.","journal-title":"Brain Res"},{"issue":"2","key":"4715_CR61","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/S0306-4522(01)00302-5","volume":"107","author":"ID Manns","year":"2001","unstructured":"Manns ID, Mainville L, Jones BE. Evidence for glutamate, in addition to acetylcholine and GABA, neurotransmitter synthesis in basal forebrain neurons projecting to the entorhinal cortex. Neuroscience. 2001;107(2):249\u201363.","journal-title":"Neuroscience"},{"key":"4715_CR62","first-page":"69","volume-title":"Alzheimer disease","author":"C Geula","year":"1999","unstructured":"Geula C, Mesulam MM. Cholinergic systems in Alzheimer\u2019s disease. In: Terry RD, et al. editors. Alzheimer disease. 2nd ed. Philadelphia, PA: Lippincott, Williams & Wilkins; 1999. pp. 69\u2013292.","edition":"2"},{"key":"4715_CR63","doi-asserted-by":"publisher","first-page":"1312","DOI":"10.1152\/jn.2001.86.3.1312","volume":"86","author":"JH Jhamandas","year":"2001","unstructured":"Jhamandas JH, Cho C, Jassar B, Harris K, MacTavish D, Easaw J. Cellular mechanisms for amyloid \u2013protein activation of rat cholinergic basal forebrain neurons. J Neurophysiol. 2001;86:1312\u201320.","journal-title":"J Neurophysiol"},{"doi-asserted-by":"crossref","unstructured":"Pe\u00f1a F, Guti\u00e9rrez-Lerma AI, Quiroz-Baez R, Arias C\/. \/ The role of \u03b2-Amyloid protein in synaptic function: implications for Alzheimer\u2019s Disease Therapy.\/\/ CurrNeuropharmacol. 2006; 4(2): 149\u201363.","key":"4715_CR64","DOI":"10.2174\/157015906776359531"},{"key":"4715_CR65","doi-asserted-by":"publisher","first-page":"841","DOI":"10.3233\/JAD-2012-121447","volume":"33","author":"R Ni","year":"2013","unstructured":"Ni R, Marutle A, Nordberg A. Modulation of \u03b17 nicotinic acetylcholine receptor and fibrillar amyloid-\u03b2 interactions in Alzheimer\u2019s disease brain. J Alzheimers Dis. 2013;33:841\u201351.","journal-title":"J Alzheimers Dis"},{"key":"4715_CR66","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/bs.irn.2015.08.002","volume":"124","author":"J Shen","year":"2015","unstructured":"Shen J, Wu J. Nicotinic cholinergic mechanisms in Alzheimer\u2019s disease. Int Rev Neurobiol. 2015;124:275\u201392.","journal-title":"Int Rev Neurobiol"},{"key":"4715_CR67","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1016\/j.conb.2004.10.011","volume":"14","author":"JM Ramirez","year":"2004","unstructured":"Ramirez JM, Tryba AK, Pena F. Pacemaker neurons and neuronal networks: an integrative view. Curr Opin Neurobiol. 2004;14:665\u201374.","journal-title":"Curr Opin Neurobiol"},{"issue":"14","key":"4715_CR68","doi-asserted-by":"publisher","first-page":"2170","DOI":"10.1016\/j.neuron.2023.04.020","volume":"111","author":"M Colom-Cadena","year":"2023","unstructured":"Colom-Cadena M, Davies C, Sirisi S, Lee JE, Simzer EM, Tzioras M, Querol-Vilaseca M, S\u00e1nchez-Aced \u00c9, Chang YY, Holt K, McGeachan RI, Rose J, Tulloch J, Wilkins L, Smith C, Andrian T, Belbin O, Pujals S, Horrocks MH, Lle\u00f3 A, Spires-Jones TL. Synaptic oligomeric tau in Alzheimer\u2019s disease - A potential culprit in the spread of tau pathology through the brain. Neuron. 2023;111(14):2170\u2013e21836.","journal-title":"Neuron"},{"key":"4715_CR69","doi-asserted-by":"publisher","first-page":"17301","DOI":"10.1074\/jbc.M010450200","volume":"276","author":"L Tong","year":"2001","unstructured":"Tong L, Thornton PL, Balazs R, Cotman CW. \u03b2-amyloid-1\u201342 impairs activity-dependent cAMP-response elementbinding protein signaling in neurons at concentrations in which cell survival is not compromised. J Biol Chem. 2001;276:17301\u20136.","journal-title":"J Biol Chem"},{"issue":"1","key":"4715_CR70","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1046\/j.1471-4159.2001.00054.x","volume":"76","author":"JD Sweatt","year":"2001","unstructured":"Sweatt JD. The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory. J Neurochem. 2001;76(1):1\u201310.","journal-title":"J Neurochem"},{"key":"4715_CR71","doi-asserted-by":"publisher","first-page":"1317","DOI":"10.1016\/S0006-291X(02)02072-7","volume":"296","author":"C Rovira","year":"2002","unstructured":"Rovira C, Arbez N, Mariani J. A(25\u201335) and A(1\u201340) act on different calcium channels in CA1 hippocampal neurons. Biochem Biophys Res Commun. 2002;296:1317\u201321.","journal-title":"Biochem Biophys Res Commun"},{"key":"4715_CR72","doi-asserted-by":"publisher","first-page":"5703","DOI":"10.1523\/JNEUROSCI.21-15-05703.2001","volume":"21","author":"A Stephan","year":"2001","unstructured":"Stephan A, Laroche S, Davis S. Generation of aggregated-amyloid in the rat hippocampus impairs synaptic transmission and plasticity and causes memory deficits. J Neurosci. 2001;21:5703\u201314.","journal-title":"J Neurosci"},{"key":"4715_CR73","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1038\/416535a","volume":"416","author":"DM Walsh","year":"2002","unstructured":"Walsh DM, Klyubin I, Fadeeva JV, Cullen WK, Anwyl R, Wolfe MS, Rowan MJ. Selkoe D.J. naturally secreted oligomers of amyloid protein potently inhibit hippocampal longterm potentiation in vivo. Nature. 2002;416:535\u20139.","journal-title":"Nature"},{"key":"4715_CR74","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1146\/annurev.physiol.64.092501.114547","volume":"64","author":"RS Zucker","year":"2002","unstructured":"Zucker RS, Regehr WG. Short-term synaptic plasticity. Annu Rev Physiol. 2002;64:355\u2013405.","journal-title":"Annu Rev Physiol"},{"issue":"8","key":"4715_CR75","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1038\/nn1503","volume":"8","author":"EM Snyder","year":"2005","unstructured":"Snyder EM, Nong Y, Almeida CG, Paul S, Moran T, Choi EY, Nairn AC, Salter MW, Lombroso PJ, Gouras GK, Greengard P. Regulation of NMDA receptor trafficking by amyloid-beta. Nat Neurosci. 2005;8(8):1051\u20138.","journal-title":"Nat Neurosci"},{"key":"4715_CR76","doi-asserted-by":"publisher","first-page":"106711","DOI":"10.1016\/j.phrs.2023.106711","volume":"190","author":"F Bono","year":"2023","unstructured":"Bono F, Fiorentini C, Mutti V, Tomasoni Z, Sbrini G, Trebesova H, Marchi M, Grilli M, Missale C. Central nervous system interaction and crosstalk between nAChRs and other ionotropic and metabotropic neurotransmitter receptors. Pharmacol Res. 2023;190:106711.","journal-title":"Pharmacol Res"},{"key":"4715_CR77","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1038\/aps.2009.24","volume":"30","author":"XX Dong","year":"2009","unstructured":"Dong XX, Wang Y, Qin Z. Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases. Acta Pharmacol Sin. 2009;30:379\u201387.","journal-title":"Acta Pharmacol Sin"},{"issue":"2","key":"4715_CR78","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.pneurobio.2010.06.004","volume":"92","author":"M Marchi","year":"2010","unstructured":"Marchi M, Grilli M. Presynaptic nicotinic receptors modulating neurotransmitter release in the central nervous system: functional interactions with other coexisting receptors. Prog Neurobiol. 2010;92(2):105\u201311.","journal-title":"Prog Neurobiol"},{"key":"4715_CR79","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/S0896-6273(01)00332-4","volume":"31","author":"D Ji","year":"2001","unstructured":"Ji D, Lape R, Dani JA. Timing and location of nicotinic activity enhances or depresses hippocampal synaptic plasticity. Neuron. 2001;31:131\u201341.","journal-title":"Neuron"},{"issue":"3","key":"4715_CR80","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1177\/2040622310397691","volume":"2","author":"J Kawamata","year":"2011","unstructured":"Kawamata J, Suzuki S, Shimohama S. Enhancement of nicotinic receptors alleviates cytotoxicity in neurological disease models. Ther Adv Chronic Dis. 2011;2(3):197\u2013208.","journal-title":"Ther Adv Chronic Dis"},{"key":"4715_CR81","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1523\/JNEUROSCI.3501-06.2007","volume":"27","author":"PN Lacor","year":"2007","unstructured":"Lacor PN, Buniel MC, Furlow PW, et al. Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer\u2019s disease. J Neurosci. 2007;27:796\u2013807.","journal-title":"J Neurosci"},{"key":"4715_CR82","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1002\/cne.902750205","volume":"275","author":"MM Mesulam","year":"1988","unstructured":"Mesulam MM, C. Nucleus basalis (Ch4) and cortical cholinergic innervation in the human brain: observations based on the distribution of acetylcholinesterase and choline acetyltransferase. J Comp Neurol. 1988;275:216\u201340.","journal-title":"J Comp Neurol"},{"key":"4715_CR83","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/0306-4522(84)90234-3","volume":"13","author":"AI Levey","year":"1984","unstructured":"Levey AI, Wainer BH, Rye DB, Mufson EJ, Mesulam MM. Choline acetyltransferase-immunoreactive neurons intrinsic to rodent cortex and distinction from acetylcholinesterase-positive neurons. Neuroscience. 1984;13:341\u201353.","journal-title":"Neuroscience"},{"issue":"5","key":"4715_CR84","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1016\/j.neuron.2007.07.025","volume":"55","author":"JJ Palop","year":"2007","unstructured":"Palop JJ, Chin J, Roberson ED, Wang J, Thwin MT, Bien-Ly N, Yoo J, Ho KO, Yu GQ, Kreitzer A, Finkbeiner S, Noebels JL, Mucke L. Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer\u2019s disease. Neuron. 2007;55(5):697\u2013711.","journal-title":"Neuron"},{"key":"4715_CR85","doi-asserted-by":"publisher","first-page":"767","DOI":"10.3390\/molecules19010767","volume":"19","author":"S Vladimir-Kne\u017eevi\u00b4c","year":"2014","unstructured":"Vladimir-Kne\u017eevi\u00b4c S, Bla\u017eekovi\u00b4c B, Kindl M, Vladi\u00b4c J, Lower-Nedza AD, Brantner AH. Acetylcholinesterase inhibitory, antioxidant and phytochemical properties of selected medicinal plants of the Lamiaceae family. Molecules. 2014;19:767\u201382.","journal-title":"Molecules"},{"issue":"1","key":"4715_CR86","doi-asserted-by":"publisher","first-page":"BR41","DOI":"10.12659\/MSM.882201","volume":"18","author":"P Hasanein","year":"2012","unstructured":"Hasanein P, Shahidi S. Preventive effect of Teucrium Poliumon learning and memory deficits in diabetic rats. Med Sci Monit. 2012;18(1):BR41\u20136.","journal-title":"Med Sci Monit"},{"doi-asserted-by":"crossref","unstructured":"Bahramikia S, Yazdanparast R. Phytochemistry and Medicinal Properties of Teucrium polium L. (Lamiaceae). Phytother Res. 2012;26(11):1581\u201393.","key":"4715_CR87","DOI":"10.1002\/ptr.4617"},{"key":"4715_CR88","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.brainres.2009.05.101","volume":"1283","author":"H Wang","year":"2009","unstructured":"Wang H, Xu Y, Yan J, Zhao X, Sun X, Zhang Y, Guo J, Zhu C. Acteoside protects human neuroblastoma SH-SY5Y cells against beta-amyloid-induced cell injury. Brain Res. 2009;1283:139\u201347.","journal-title":"Brain Res"},{"key":"4715_CR89","doi-asserted-by":"publisher","first-page":"1329","DOI":"10.1271\/bbb.130101","volume":"77","author":"M Kurisu","year":"2013","unstructured":"Kurisu M, Miyamae Y, Murakami K, Han J, Isoda H, Irie K, Shigemor H. Inhibition of amyloid \u03b2 aggregation by Acteoside, a phenylethanoid glycoside. Biosci Biotechnol Biochem. 2013;77:1329\u201332.","journal-title":"Biosci Biotechnol Biochem"},{"key":"4715_CR90","first-page":"78","volume":"53","author":"L Korkina","year":"2006","unstructured":"Korkina L, Mikhal\u2019chik E, Suprun M, Pastore S. DT. Molecular mechanisms underlying wound healing and anti-inflammatory properties of naturally occurring biotechnologically produced phenylpropanoid glycosides. Cell Mol Biology. 2006;53:78\u201383.","journal-title":"Cell Mol Biology"},{"issue":"3","key":"4715_CR91","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1093\/ecam\/nel028","volume":"3","author":"P Ljubuncic","year":"2006","unstructured":"Ljubuncic P, Dakwar S, Portnaya I, Cogan U, Azaizeh H, Bomzon A. Aqueous extracts of Teucrium polium possess remarkable antioxidant activity in vitro. Evid Based Complement Alternat Med. 2006;3(3):329\u201338.","journal-title":"Evid Based Complement Alternat Med"},{"key":"4715_CR92","first-page":"493729","volume":"2015","author":"SM Mousavi","year":"2015","unstructured":"Mousavi SM, Niazmand S, Hosseini M, Hassanzadeh Z, Sadeghnia HR, Vafaee F, Keshavarzi Z. Beneficial effects of Teucrium Polium and Metformin on Diabetes-Induced memory impairments and brain tissue oxidative damage in rats. Int J Alzheimers Dis. 2015;2015:493729.","journal-title":"Int J Alzheimers Dis"},{"key":"4715_CR93","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.lfs.2018.01.013","volume":"196","author":"H Khan","year":"2018","unstructured":"Khan H, Amin S, Patel S. Targeting BDNF modulation by plant glycosides as a novel therapeutic strategy in the treatment of depression. Life Sci. 2018;196:18\u201327.","journal-title":"Life Sci"},{"key":"4715_CR94","doi-asserted-by":"publisher","first-page":"208","DOI":"10.12659\/MSMBR.889344","volume":"19","author":"M Rafieian-Kopaei","year":"2013","unstructured":"Rafieian-Kopaei M, Nasri H. Comment on: preventive effect of Teucrium polium on learning and memory deficits in diabetic rats. Med Sci Monit Basic Res. 2013;19:208\u20139.","journal-title":"Med Sci Monit Basic Res"},{"issue":"\u2013 4","key":"4715_CR95","first-page":"p49","volume":"\u2013 LV","author":"H\u041c Galstyan","year":"2015","unstructured":"Galstyan H\u041c, Pepanyan \u0410\u0410, Dagbashyan SS, Chichoyan NB, Simonyan KV, Chavushyan V\u0410. The effect of administration of fractions of hydroponic Teucrium poliumLamiaceae on the blood biochemical parameters characterizing the functional activity of the liver. J Med Sci Armen. 2015;\u2013 LV(\u2013 4):p49\u201358.","journal-title":"J Med Sci Armen"},{"key":"4715_CR96","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1007\/s12017-009-8091-0","volume":"12","author":"T Ondrejcak","year":"2010","unstructured":"Ondrejcak T, Klyubin I, Hu N-W, Barry AE, Cullen WK, Rowan MJ. Alzheimer\u2019s disease amyloid b-Protein and synaptic function. Neuromol Med. 2010;12:13\u201326.","journal-title":"Neuromol Med"},{"issue":"Pt 5","key":"4715_CR97","doi-asserted-by":"publisher","first-page":"1219","DOI":"10.1042\/BST0351219","volume":"35","author":"MJ Rowan","year":"2007","unstructured":"Rowan MJ, Klyubin I, Wang Q, Hu NW, Anwyl R. Synaptic memory mechanisms: Alzheimer\u2019s disease amyloid beta-peptide-induced dysfunction. Biochem Soc Trans. 2007;35(Pt 5):1219\u201323.","journal-title":"Biochem Soc Trans"},{"issue":"4","key":"4715_CR98","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1038\/s41593-018-0080-x","volume":"21","author":"B Styr","year":"2018","unstructured":"Styr B, Slutsky I. Imbalance between firing homeostasis and synaptic plasticity drives early-phase Alzheimer\u2019s disease. Nat Neurosci. 2018;21(4):463\u201373.","journal-title":"Nat Neurosci"},{"issue":"4","key":"4715_CR99","doi-asserted-by":"publisher","first-page":"106315","DOI":"10.1016\/j.isci.2023.106315","volume":"26","author":"C Li","year":"2023","unstructured":"Li C, Zhang X, Chen P, Zhou K, Yu J, Wu G, Xiang D, Jiang H, Wang M, Liu Q. Short-term synaptic plasticity in emerging devices for neuromorphic computing. iScience. 2023;26(4):106315.","journal-title":"iScience"},{"issue":"2","key":"4715_CR100","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1038\/nrn1327","volume":"5","author":"GG Turrigiano","year":"2004","unstructured":"Turrigiano GG, Nelson SB. Homeostatic plasticity in the developing nervous system. Nat Rev Neurosci. 2004;5(2):97\u2013107.","journal-title":"Nat Rev Neurosci"},{"issue":"2","key":"4715_CR101","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.tins.2004.12.003","volume":"28","author":"WC Abraham","year":"2005","unstructured":"Abraham WC, Robins A. Memory retention\u2013the synaptic stability versus plasticity dilemma. Trends Neurosci. 2005;28(2):73\u20138.","journal-title":"Trends Neurosci"},{"issue":"2","key":"4715_CR102","doi-asserted-by":"publisher","first-page":"181","DOI":"10.31887\/DCNS.2017.19.2\/wcarlezon","volume":"19","author":"KR Lezak","year":"2017","unstructured":"Lezak KR, Missig G, Carlezon WA Jr. Behavioral methods to study anxiety in rodents. Dialogues Clin Neurosci. 2017;19(2):181\u201391.","journal-title":"Dialogues Clin Neurosci"},{"issue":"22","key":"4715_CR103","doi-asserted-by":"publisher","first-page":"e2203680119","DOI":"10.1073\/pnas.2203680119","volume":"119","author":"YF Chen","year":"2022","unstructured":"Chen YF, Song Q, Colucci P, Maltese F, Siller-P\u00e9rez C, Prins K, McGaugh JL, Hermans EJ, Campolongo P, Nadif Kasri N, Roozendaal B. Basolateral amygdala activation enhances object recognition memory by inhibiting anterior insular cortex activity. Proc Natl Acad Sci U S A. 2022;119(22):e2203680119.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"4715_CR104","doi-asserted-by":"publisher","first-page":"e27756","DOI":"10.7554\/eLife.27756","volume":"6","author":"Z Brzosko","year":"2017","unstructured":"Brzosko Z, Zannone S, Schultz W, Clopath C, Paulsen O. Sequential neuromodulation of hebbian plasticity offers mechanism for effective reward-based navigation. Elife. 2017;6:e27756.","journal-title":"Elife"},{"issue":"16","key":"4715_CR105","doi-asserted-by":"publisher","first-page":"2557","DOI":"10.1016\/j.cub.2018.06.064","volume":"28","author":"T Aitta-Aho","year":"2018","unstructured":"Aitta-Aho T, Hay YA, Phillips BU, Saksida LM, Bussey TJ, Paulsen O, Apergis-Schoute J. Basal forebrain and brainstem cholinergic neurons differentially Impact Amygdala circuits and Learning-related behavior. Curr Biol. 2018;28(16):2557\u2013e25694.","journal-title":"Curr Biol"},{"issue":"1","key":"4715_CR106","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.neuroimage.2003.09.042","volume":"21","author":"K Herholz","year":"2004","unstructured":"Herholz K, Weisenbach S, Z\u00fcndorf G, Lenz O, Schr\u00f6der H, Bauer B, Kalbe E, Heiss WD. In vivo study of acetylcholine esterase in basal forebrain, amygdala, and cortex in mild to moderate Alzheimer disease. NeuroImage. 2004;21(1):136\u201343.","journal-title":"NeuroImage"}],"container-title":["BMC Complementary Medicine and Therapies"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12906-024-04715-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12906-024-04715-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12906-024-04715-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,30]],"date-time":"2025-03-30T17:24:24Z","timestamp":1743355464000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmccomplementalternmed.biomedcentral.com\/articles\/10.1186\/s12906-024-04715-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,27]]},"references-count":106,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["4715"],"URL":"https:\/\/doi.org\/10.1186\/s12906-024-04715-8","relation":{},"ISSN":["2662-7671"],"issn-type":[{"type":"electronic","value":"2662-7671"}],"subject":[],"published":{"date-parts":[[2025,3,27]]},"assertion":[{"value":"15 October 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 November 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 March 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"<!--Emphasis Type='Bold' removed-->Ethics declarations"}},{"value":"All animal procedures were performed under the supervision of the institutional ethics committee of Yerevan State Medical University after Mkhitar Heratsi, Yerevan, Armenia (approved code: N4 IRB). The ARRIVE guidelines for the care and use of laboratory animals were also followed.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"There are no actual or potential competing interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"116"}}