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The use and treatment of animals, as well as how to design the study and the procedures that were taken during this investigation, including animal use and care, were reviewed and approved by the Guangzhou Ruiye Animal Experiments Ethics Committee (No: A202309014). The study is reported in accordance with ARRIVE guidelines.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"14"}}